Treg subsets in inflammatory bowel disease and colorectal carcinoma: Characteristics, role, and therapeutic targets.

abstract：BACKGROUND:The expressions of CD95 (Fas/APO-1) and Bcl-2 are determinants of apoptosis in normal lymphocytes, and abnormalities in their expressions might contribute to the induction of autoimmunity. In this study, we examined the expressions of CD95 and Bcl-2 on freshly isolated T and B cells from patients with autoim...

journal_title：Journal of gastroenterology and hepatology

authors： Ogawa S,Sakaguchi K,Takaki A,Shiraga K,Sawayama T,Mouri H,Miyashita M,Koide N,Tsuji T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The pathogenesis of non-alcoholic steatohepatitis (NASH) is unclear. Recent studies suggested that oxidative stress plays an important role in the mechanism of NASH. Excessive accumulation of iron in the liver causes oxidative stress. The aim of the present study was to evaluate the grade of hepatic iron acc...

journal_title：Journal of gastroenterology and hepatology

authors： Yamamoto M,Iwasa M,Iwata K,Kaito M,Sugimoto R,Urawa N,Mifuji R,Konishi M,Kobayashi Y,Adachi Y

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Absolute lymphocyte count (ALC) and the recovery of ALC after treatment have been identified as a prognostic biomarker for several malignancies. In this study, we aimed to investigate the prognostic role of peritransplant ALC and ALC recovery after liver transplantation (LT) in hepatocellular carcin...

journal_title：Journal of gastroenterology and hepatology

authors： Zheng Z,Lin B,Zhang J,Yang Z,Xie H,Zhou L,Zhang M,Zheng S

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND AIM:Histological criteria for intracapsular venous invasion (IVI) that would allow its discrimination between portal and hepatic venous invasion in hepatocellular carcinoma (HCC) have not been established. METHODS:We evaluated IVI immunohistochemically to discriminate between portal and hepatic venous i...

journal_title：Journal of gastroenterology and hepatology

authors： Ohashi M,Wakai T,Korita PV,Ajioka Y,Shirai Y,Hatakeyama K

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Liver biopsy is the gold standard test to determine the grade of fibrosis, but there are associated problems. Because gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid is secreted partially in hepatocytes and bile, it is possible that ethoxybenzyl-magnetic resonance imaging (EOB-MRI) corre...

journal_title：Journal of gastroenterology and hepatology

authors： Nojiri S,Kusakabe A,Fujiwara K,Shinkai N,Matsuura K,Iio E,Miyaki T,Joh T

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:It has been reported that cathepsin E (CTSE) is a non-secretory and intracellular aspartic proteinase found in the superficial epithelial cells of the stomach and that it is also expressed in pancreatic ductal adenocarcinoma. We evaluated the diagnostic value of CTSE in the pancreatic juice in the diagnosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Uno K,Azuma T,Nakajima M,Yasuda K,Hayakumo T,Mukai H,Sakai T,Kawai K

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND AIM:Splenomegaly in a common finding in liver cirrhosis that should determine changes in the spleen's density because of portal and splenic congestion and/or because of tissue hyperplasia and fibrosis. These changes might be quantified by elastography, so the aim of the study was to investigate whether s...

journal_title：Journal of gastroenterology and hepatology

authors： Stefanescu H,Grigorescu M,Lupsor M,Procopet B,Maniu A,Badea R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:A daily injection of glycyrrhizin (Stronger Neo-Minophagen C (SNMC) containing 40 mg glycyrrhizin in a 20 mL ampoule) lowers alanine aminotransferase (ALT) levels in patients with chronic viral hepatitis. METHODS:The therapeutic effects of intermittent administration of SNMC three times a week for 12 weeks ...

journal_title：Journal of gastroenterology and hepatology

authors： Miyake K,Tango T,Ota Y,Mitamura K,Yoshiba M,Kako M,Hayashi S,Ikeda Y,Hayashida N,Iwabuchi S,Sato Y,Tomi T,Funaki N,Hashimoto N,Umeda T,Miyazaki J,Tanaka K,Endo Y,Suzuki H

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND AND AIM:The PyloriTek Test Kit (a 1-h rapid urease test) was developed for the rapid diagnosis of Helicobacter pylori (H. pylori) during endoscopy. Most studies were performed in Western populations. The aim of this study was to evaluate the PyloriTek test for the diagnosis of H. pylori infection in Chinese ...

journal_title：Journal of gastroenterology and hepatology

authors： Wong WM,Wong BC,Tang VS,Lai KC,Yuen ST,Leung SY,Hu WH,Lam SK

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The high recurrence of hepatolithiasis and high operative trauma of hepatectomy necessitate new therapeutic approaches. Thus, this study was designed to (i) investigate the effectiveness of chemical biliary duct embolization (CBDE) for chemical hepatectomy; and (ii) to determine the mechanism of CBD...

journal_title：Journal of gastroenterology and hepatology

authors： Li FY,Cheng JQ,Li N,He S,Zhang MM,Dong JH,Jiang LS,Cheng NS

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Enriched blood vessels occur in the stroma of Barrett's esophagus and are related to the ease of tumor invasion in the early stage of the cancer. Hypoxia-inducible factor (HIF) is closely related with angiogenesis through expression of vascular endothelial growth factor. The aim of the present study was to d...

journal_title：Journal of gastroenterology and hepatology

authors： Moriyama N,Amano Y,Mishima Y,Okita K,Takahashi Y,Yuki T,Ishimura N,Ishihara S,Kinoshita Y

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Anti-neutrophil cytoplasmic antibodies (ANCA) against proteinase 3 are diagnostic of Wegener's granulomatosis, but ANCA occur also in patients with other inflammatory disorders, such as ulcerative colitis, primary sclerosing cholangitis (PSC) and autoimmune hepatitis. As their predictive value for autoimmune...

journal_title：Journal of gastroenterology and hepatology

authors： Lindgren S,Nilsson S,Nässberger L,Verbaan H,Wieslander J

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Antibody against hepatitis B surface antigen (HBsAg) is used for passive immunotherapy in certain cases of hepatitis B infection. The authors have earlier reported a high-affinity mouse monoclonal (5S) against HBsAg. However, this mouse antibody cannot be used for therapeutic purposes because it may elicit a...

journal_title：Journal of gastroenterology and hepatology

authors： Bose B,Khanna N,Acharya SK,Sinha S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known about the role of hepatitis B virus (HBV) factors in the long-term prognosis of hepatocellular carcinoma (HCC) after resection. The objective of the present study was to identify the changing patterns of HBV levels and its effect on outcome after resection. METHODS:This study recruit...

journal_title：Journal of gastroenterology and hepatology

authors： An HJ,Jang JW,Bae SH,Choi JY,Cho SH,Yoon SK,Han JY,Lee KH,Kim DG,Jung ES

更新日期：2010-12-01 00:00:00

abstract：:The incidence of obesity is increasing in Asia, with implications on gastrointestinal (GI) and liver diseases. The Gut and Obesity in Asia Workgroup comprises regional experts with the aim of studying relationship between obesity and the GI and liver diseases in Asia. Through literature review and the modified Delphi ...

journal_title：Journal of gastroenterology and hepatology

authors： Koh JC,Loo WM,Goh KL,Sugano K,Chan WK,Chiu WY,Choi MG,Gonlachanvit S,Lee WJ,Lee WJ,Lee YY,Lesmana LA,Li YM,Liu CJ,Matsuura B,Nakajima A,Ng EK,Sollano JD,Wong SK,Wong VW,Yang Y,Ho KY,Dan YY

更新日期：2016-08-01 00:00:00

abstract：:This study evaluates the immune response of 20 haemodialysis (HD) patients vaccinated with hepatitis A (HA) vaccine and eight patients vaccinated with hepatitis B (HB) vaccine. Twenty patients and 22 healthy adults were immunized three times (months 0, 1 and 6) intramuscularly with a 0.5 microgram dose. All members of...

journal_title：Journal of gastroenterology and hepatology

authors： Kuramoto I,Fujiyama S,Matsushita K,Sato T

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND AIM:Non-invasive diagnosis of colorectal disease remains problematic, fecal biomarkers presenting the only current option. Colorectal mucus is the diagnostically informative element of stool samples, but its separation from stool is difficult. We aimed to: (i) test a novel method of non-invasive colorect...

journal_title：Journal of gastroenterology and hepatology

authors： Loktionov A,Chhaya V,Bandaletova T,Poullis A

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND AIM:Little information is available about the antiviral efficacy of lamivudine (LAM) and entecavir (ETV) in patients with hepatitis B virus (HBV)-related advanced hepatocellular carcinoma (HCC). Thus, we compared the antiviral efficacy of LAM and ETV in these patients. METHODS:The medical records of 134...

journal_title：Journal of gastroenterology and hepatology

authors： Shin HS,Kim SU,Park JY,Kim DY,Han KH,Chon CY,Baatarkhuu O,Ahn SH

更新日期：2012-09-01 00:00:00

abstract：:First-degree relatives of colorectal cancer patients are at increased risk for developing colorectal neoplasms. In order to assess the potentiality of colonoscopy screening in this high-risk population, 213 asymptomatic family members (age range 30-69 years, mean 42.8 years) of those patients with colorectal cancer re...

journal_title：Journal of gastroenterology and hepatology

authors： Wu CS,Tung SY,Chen PC,Kuo YC

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to evaluate the influence of a younger age at the time of ileal pouch-anal anastomosis (IPAA) on functional outcome and quality of life in patients with familial adenomatous polyposis (FAP). METHOD:A total of 105 patients with FAP who had undergone IPAA were retrieved from a...

journal_title：Journal of gastroenterology and hepatology

authors： Erkek AB,Church JM,Remzi FH

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Balloon-occluded retrograde transvenous obliteration (B-RTO) is an effective treatment for gastric varices (GVx), as well as hepatic encephalopathy. The aim of this study was to examine the changes of the hepatic vein pressure gradient (HVPG) after B-RTO and determine the relation between the change...

journal_title：Journal of gastroenterology and hepatology

authors： Uehara H,Akahoshi T,Tomikawa M,Kinjo N,Hashimoto N,Nagao Y,Kamori M,Maehara Y

更新日期：2012-01-01 00:00:00

abstract：:AL amyloidosis complicating multiple myeloma is rare but well recognized. Endoscopic appearances of amyloid in the gastrointestinal tract can, however, be highly variable. Macroscopic appearances of the duodenum can range from scalloping (often seen in celiac disease) to that of duodenitis; erosive disease, frank ulce...

journal_title：Journal of gastroenterology and hepatology

authors： Hurlstone DP

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:A nitroxide radical, 4-hydroxyl-2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPOL), is directly reduced to hydroxylamine by ascorbic acid (AsA). Ascorbic acid is oxidized to dehydroascorbic acid (DHA) by ascorbic acid oxidase (AAOx), and DHA is reduced to AsA by glutathione (GSH). In the present study, in vivo and...

journal_title：Journal of gastroenterology and hepatology

authors： Tada M,Yokoyama H,Ito O,Ohya H,Ogata T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND AIM:Increased production of reactive oxygen species, which cause oxidative DNA damage, is considered to be related to hepatocarcinogenesis. 8-Hydroxy-2'-deoxy-guanosine (8-OHdG) is a useful marker of DNA damage induced by oxidative stress. The aim of this study was to determine whether expression of 8-OH...

journal_title：Journal of gastroenterology and hepatology

authors： Chuma M,Hige S,Nakanishi M,Ogawa K,Natsuizaka M,Yamamoto Y,Asaka M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND AIM:Although several molecular biomarkers for esophageal adenocarcinoma (EAC) have been shown to be useful disease indicators, none has been established as a reliable indicator for risk of EAC or have progressed to routine use. The aim was to identify biomarkers of high risk for EAC in patients with Barr...

journal_title：Journal of gastroenterology and hepatology

authors： Murao T,Shiotani A,Fujita Y,Yamanaka Y,Kamada T,Manabe N,Hata J,Nishio K,Haruma K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Aberrant right subclavian artery (ARSA) is the most common congenital anomaly of the aortic arch occurring in 0.4-2.0% of the general population. Instead of arising from the brachiocephalic artery, the ARSA arises as the last branch from the aortic arch. The aim of this study was to determine the pr...

journal_title：Journal of gastroenterology and hepatology

authors： Yusuf TE,Levy MJ,Wiersema MJ,Clain JE,Harewood GC,Rajan E,Topazian MD,Wang KK

更新日期：2007-11-01 00:00:00

abstract：:Significant bile leak is an uncommon but serious complication of biliary tract surgery. Of twenty-five patients presenting with postoperative bile leak, 11 had complete tie-off of common bile duct and required surgery, while the remaining 14 had injury without complete obstruction and could be managed by endoscopic me...

journal_title：Journal of gastroenterology and hepatology

authors： Saraswat VA,Choudhuri G,Sharma BC,Agarwal DK,Gupta R,Baijal SS,Sikora SS,Saxena R,Kapoor VK

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of the study was to develop a method of quantitation of endoscopic ultrasonography (EUS) changes of chronic pancreatitis (CP). METHODS:Twenty-three patients with chronic pancreatitis by EUS were compared with nine normal subjects. Hyperechogenicity was evaluated as the size of the hyperechoi...

journal_title：Journal of gastroenterology and hepatology

authors： Irisawa A,Mishra G,Hernandez LV,Bhutani MS

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND AIM:After selective biliary access following precut fistulotomy in difficult biliary cannulations (DBC), there are several methods of completely opening the remaining papillary roof for the removal of biliary stones. We evaluated the efficacy of one-step transfistula balloon dilation following fistulotom...

journal_title：Journal of gastroenterology and hepatology

authors： Jun BG,Lee TH,Jeong S,Hwang JC,Yang MJ,Song TJ,Choi HJ,Moon JH,Park SH

更新日期：2014-01-01 00:00:00

abstract：:Although the advancement of molecular oncology in gastric cancer lags behind that of colorectal cancer, the rapid developments witnessed in recent years have improved our understanding of the carcinogenesis, aetiology, progression and metastasis of gastric cancer. The different molecular genetic alterations in intesti...

journal_title：Journal of gastroenterology and hepatology

authors： Chan AO,Luk JM,Hui WM,Lam SK

更新日期：1999-12-01 00:00:00