Resolution of tumor pain with EMLA cream.

abstract：STUDY OBJECTIVE:To develop and evaluate a peer review group (PRG) meeting using feedback data on a patient level to improve the quality of drug therapy for prevention of recurrent myocardial infarction. DESIGN:Prospective follow-up study. DATA SOURCE:General practitioners' computerized patients records (intervention ...

journal_title：Pharmacotherapy

authors： van der Elst ME,Bouvy ML,de Blaey CJ,de Boer A

更新日期：2006-02-01 00:00:00

abstract：:Diurnal variation in plasma norepinephrine (PNE) levels is well documented in healthy individuals but not in patients with heart failure. Therefore, we attempted to determine variations in PNE levels over 24 hours, measured hourly, in six patients with an ejection fraction below 40% and a history of heart failure of l...

journal_title：Pharmacotherapy

authors： Bleske BE,Chung HS,DiMagno M,Nicklas JM

更新日期：1999-08-01 00:00:00

abstract：:Nausea and vomiting are common complaints in the postoperative period and contribute to patient distress and delay of discharge for outpatient surgical procedures. Laparoscopic procedures are associated with a high incidence of postoperative nausea and vomiting (PONV) episodes. Parenteral use of metoclopramide prevent...

journal_title：Pharmacotherapy

authors： Wagner BK,Berman SL,Devitt PA,Halvorsen MB,O'Hara DA

更新日期：1996-11-01 00:00:00

abstract：STUDY OBJECTIVE:To categorize institutional review board (IRB) challenges and solutions encountered in a multicenter practice-based research network (PBRN) study and to assess the impact of IRB requirements on the willingness of individual principal investigators (PIs) to participate in future PBRN studies. DESIGN:Des...

journal_title：Pharmacotherapy

authors： Maclaughlin EJ,Ardery G,Jackson EA,Ives TJ,Young RB,Fike DS,Carter BL

更新日期：2013-09-01 00:00:00

abstract：STUDY OBJECTIVE:To investigate the relationship between two widely used, generic health-related quality of life (HRQOL) measures, Short Form-12 (SF-12) and EuroQol's EQ-5D, and potentially inappropriate drug use in an elderly cohort. DESIGN:Longitudinal retrospective cohort study. DATA SOURCE:Medical Expenditure Pane...

journal_title：Pharmacotherapy

authors： Franic DM,Jiang JZ

更新日期：2006-06-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the prevalence, over 40 years, of using the last-observation-carried-forward (LOCF) imputation method in clinical trials, the association between use of LOCF and how the trials were conducted, and the extent of information about attrition and LOCF use in published reports. DESIGN:Retrospec...

journal_title：Pharmacotherapy

authors： Woolley SB,Cardoni AA,Goethe JW

更新日期：2009-12-01 00:00:00

abstract：:Hormonal emergency contraceptives have been used to prevent unwanted pregnancy for more than 3 decades. The mechanisms of action of the regimen containing a combination of estrogen and progestin, known as the Yuzpe regimen, and those of the levonorgestrel regimen continue to be controversial, especially over the possi...

journal_title：Pharmacotherapy

authors： Leung VW,Levine M,Soon JA

更新日期：2010-02-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the pharmacokinetics and use of intravenous human cytomegalovirus immune globulin (CytoGam) in allogeneic bone marrow transplantation (BMT). DESIGN:Prospective, nonrandomized, nonblinded, single-center study. SETTING:University teaching hospital. PATIENTS:Five consecutive patients with he...

journal_title：Pharmacotherapy

authors： DeRienzo SY,Chiang KY,O'Neal WM,Godder K,Abhyankar S,Christiansen NP,Bridges KD,Henslee-Downey PJ

更新日期：2000-10-01 00:00:00

abstract：:Cisplatin in combination with other cytotoxic agents is the backbone for a potential cure of testicular germ cell neoplasms and is a critical factor in the substantial activity observed in the treatment of small cell lung cancer, bladder cancer, and ovarian germ cell tumors. Resistance to cisplatin at the onset of tre...

journal_title：Pharmacotherapy

authors： Gosland M,Lum B,Schimmelpfennig J,Baker J,Doukas M

更新日期：1996-01-01 00:00:00

abstract：:A major factor in delivering patient care is documenting activities by pharmacists. This documentation is not only essential to sustain existing programs but necessary to justify future growth of resources. A computerized documentation system for clinical interventions and workload activities was developed in a 340-be...

journal_title：Pharmacotherapy

authors： Zimmerman CR,Smolarek RT,Stevenson JG

更新日期：1995-03-01 00:00:00

abstract：STUDY OBJECTIVE:To determine whether recommendations made by pharmacists and accepted by hospital physicians resulted in fewer postdischarge readmissions and urgent care visits compared with recommendations that were not implemented. DESIGN:Prospective substudy of pharmacist recommendations. SETTING:Tertiary care aca...

journal_title：Pharmacotherapy

authors： Anderegg SV,Demik DE,Carter BL,Dawson JD,Farris K,Shelsky C,Kaboli P

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy of a single dose of basiliximab with two doses in preventing acute rejection in selected low-risk renal transplant recipients. METHODS:This observational study of 760 kidney transplant recipients considered to be at low immunologic risk (peak panel reactive antibody less than 10%) co...

journal_title：Pharmacotherapy

authors： Cunningham KC,Hager DR,Fischer J,D'Alessandro AM,Leverson GE,Kaufman DB,Djamali A

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of alfuzosin treatment on rate and time of stone expulsion in patients with uncomplicated distal ureteral stones. PATIENTS AND METHODS:Prospective, randomized, open-label, controlled study. Patients > 18 years of age presenting to the outpatient urology clinic with uncompl...

journal_title：Pharmacotherapy

authors： El Said NO,El Wakeel L,Kamal KM,Morad Ael R

更新日期：2015-05-01 00:00:00

abstract：:A 58-year-old man experienced an asthma exacerbation after administration of nicotine nasal spray for smoking cessation. His medical history was significant for asthma, chronic obstructive pulmonary disease, hypertension, and tobacco use when he was prescribed nicotine nasal spray for smoking cessation in an outpatien...

journal_title：Pharmacotherapy

authors： Roth MT,Westman EC

更新日期：2002-06-01 00:00:00

abstract：:Neuroleptic malignant syndrome (NMS) is an idiosyncratic and uncommon but serious adverse effect that has been reported with both typical and atypical antipsychotic agents. We describe a 58-year-old man with Down syndrome and dementia who was receiving low-dose olanzapine and rivastigmine therapy; he developed NMS 4 m...

journal_title：Pharmacotherapy

authors： Stevens DL,Lee MR,Padua Y

更新日期：2008-03-01 00:00:00

abstract：:We examined whether low doses of phenytoin, which should be associated with few dose-related side effects, may increase the levels of high-density lipoprotein (HDL) cholesterol. Of 35 healthy adult men who consented to participate, 31 completed the study. They took no medications and consumed no alcohol during the stu...

journal_title：Pharmacotherapy

authors： McKenney JM,Petrizzi KS,Briggs GC,Wright JT Jr

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Anticoagulation monitoring during transition from direct oral anticoagulants (DOAC) to heparin infusions is a significant challenge. Factor Xa inhibitors influence the heparin calibrated antifactor Xa assay. The University of Virginia (UVA) Medical Center utilized a corrected antifactor Xa assay (c-AXA) duri...

journal_title：Pharmacotherapy

authors： Plum MD,Hedrick JN,Hockman R,Bazydlo L,Palkimas S

更新日期：2020-09-01 00:00:00

abstract：:An 87-year-old African-American man came to the internal medicine clinic for a routine anticoagulation management visit. He had no complaints. His medical history was significant for stage IV-A follicular non-Hodgkin's lymphoma, atrial fibrillation, and hypertension. His long-term drug therapy consisted of warfarin, f...

journal_title：Pharmacotherapy

authors： Lee NJ,Fermo JD

更新日期：2006-04-01 00:00:00

abstract：:Use of the Molecular Adsorbent Recirculating System (MARS) as a liver support device continues to grow worldwide. Various components of the MARS circuit remove both protein-bound and water-soluble molecules. Little is known about the extent of the enhanced clearance mechanisms used in MARS therapy on drug elimination....

journal_title：Pharmacotherapy

authors： Personett HA,Larson SL,Frazee EN,Nyberg SL,El-Zoghby ZM

更新日期：2015-08-01 00:00:00

abstract：:Graves' disease is an autoimmune disorder in which inappropriate stimulation of the thyroid gland results in unregulated secretion of thyroid hormones resulting in hyperthyroidism. Graves' disease is the most common cause of autoimmune hyperthyroidism during pregnancy. Treatment options for Graves' disease include thi...

journal_title：Pharmacotherapy

authors： Prunty JJ,Heise CD,Chaffin DG

更新日期：2016-01-01 00:00:00

abstract：:Clinical pharmacists must often interpret and use data derived from observational studies when making clinical decisions and recommendations, answering drug information questions, and educating patients about drug therapy. This is the third article in a three-part series intended to enhance clinical pharmacists' under...

journal_title：Pharmacotherapy

authors： Shields KM,DiPietro NA,Kier KL

更新日期：2011-02-01 00:00:00

abstract：:After injecting the solution extracted from a Primatene Mist inhaler, a patient experienced epinephrine overdose that resulted in an acute myocardial infarction and acute renal failure. The exact amount of epinephrine injected was unknown, but was thought to be between 82.5 and 124 mg, more than 25 times higher than t...

journal_title：Pharmacotherapy

authors： Woodard ML,Brent LD

更新日期：1998-05-01 00:00:00

abstract：:Beta-blockers are an important cardiovascular drug class, recommended as first-line treatment of numerous diseases such as heart failure, hypertension, and angina, as well as treatment after myocardial infarction. However, responses to a beta-blocker are variable among patients. Results of numerous studies now suggest...

journal_title：Pharmacotherapy

authors： Shin J,Johnson JA

更新日期：2007-06-01 00:00:00

abstract：:Methamphetamine is a highly potent and addictive drug that is abused in the United States and around the world. The drug is inexpensive and easily manufactured from simple chemicals such as pseudoephedrine. These features, coupled with its long half-life and highly addictive nature, contribute to the increasing proble...

journal_title：Pharmacotherapy

authors： Romanelli F,Smith KM

更新日期：2006-08-01 00:00:00

abstract：:During the past decade, patient safety issues during care transitions have gained greater attention at both the local and national level. Readmission rates to U.S. hospitals are high, often because of poor care transitions. Serious adverse drug events (ADEs) caused by an incomplete understanding of changes in complex ...

journal_title：Pharmacotherapy

authors： American College of Clinical Pharmacy.,Hume AL,Kirwin J,Bieber HL,Couchenour RL,Hall DL,Kennedy AK,LaPointe NM,Burkhardt CD,Schilli K,Seaton T,Trujillo J,Wiggins B

更新日期：2012-11-01 00:00:00

abstract：:Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (sALCL), which is a subtype of non-Hodgkin lymphoma, are relatively uncommon lymphoproliferative types of cancer. These malignancies are highly curable with initial treatment. Nonetheless, some patients are refractory to or relapse after first- and seco...

journal_title：Pharmacotherapy

authors： Newland AM,Li JX,Wasco LE,Aziz MT,Lowe DK

更新日期：2013-01-01 00:00:00

abstract：STUDY OBJECTIVE:Bevacizumab is used in the treatment of recurrent glioblastoma, but evidence is limited on the incidence of thromboembolic complications regarding the use of this drug in real-world settings. We evaluated the risk of arterial thromboembolism (ATE) and venous thromboembolism (VTE) associated with the use...

journal_title：Pharmacotherapy

authors： Lee I,Adimadhyam S,Nutescu EA,Zhou J,Asfaw AA,Sweiss KI,Patel PR,Calip GS

更新日期：2019-09-01 00:00:00

abstract：:The management of heart failure is complex. Initiating and maintaining drug therapy in patients with heart failure can be challenging. Many factors influence the heart failure syndrome and are important to account for when evaluating these patients. Concomitant diseases such as ischemic heart disease and hypertension ...

journal_title：Pharmacotherapy

authors： Gattis WA

更新日期：2000-11-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the hemodynamic and electrocardiographic effects of a single dose of commercially available bitter-orange dried-fruit extract, which is increasingly being used in dietary supplements. DESIGN:Randomized, double-blind, placebo-controlled, crossover study. SETTING:University of Connecticut, S...

journal_title：Pharmacotherapy

authors： Min B,Cios D,Kluger J,White CM

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:There are limited markers that could facilitate individualized tacrolimus treatment in the early posttransplantation period. Genetic factors have been found to play critical roles in determining tacrolimus pharmacokinetics. OBJECTIVE:We aimed to examine the association of donor and recipient Toll-like recep...

journal_title：Pharmacotherapy

authors： Ou B,Liu Y,Zhang T,Sun Y,Chen J,Peng Z

更新日期：2019-01-01 00:00:00