Graves' Disease Pharmacotherapy in Women of Reproductive Age.

abstract：STUDY OBJECTIVE:To compare the effectiveness of weight-management medications used to assist with weight loss in real-world clinical practice in the Veterans Health Administration (VHA). DESIGN:Retrospective, multicenter, observational cohort study. DATA SOURCE:National VA Corporate Data Warehouse. PATIENTS:A total ...

journal_title：Pharmacotherapy

authors： Grabarczyk TR

更新日期：2018-01-01 00:00:00

abstract：STUDY OBJECTIVE:To compare the effectiveness of darbepoetin alfa with epoetin alfa (recombinant human erythropoietin [rHuEPO]) for achieving transfusion independence and increasing hemoglobin concentrations in critically ill patients. DESIGN:Retrospective, descriptive study. SETTING:Level I trauma center intensive ca...

journal_title：Pharmacotherapy

authors： Voils SA,Harpe SH,Brophy GM

更新日期：2007-04-01 00:00:00

abstract：:A few reports in the literature describe zidovudine (AZT) pharmacokinetics in patients undergoing hemodialysis; however, the effect of continuous ambulatory peritoneal dialysis (CAPD) on the drug's disposition has not been studied. The pharmacokinetics of AZT were evaluated in five patients, age 37-62 years, who were ...

journal_title：Pharmacotherapy

authors： Kremer D,Munar MY,Kohlhepp SJ,Swan SK,Stinnett EA,Gilbert DN,Young EW,Bennett WM

更新日期：1992-01-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the feasibility of therapeutic drug monitoring for adjusting low serum antimycobacterial concentrations in patients with both tuberculosis and advanced human immunodeficiency virus (HIV). DESIGN:Retrospective cohort study. DATA SOURCE:De-identified dataset from a tuberculosis clinic. PAT...

journal_title：Pharmacotherapy

authors： Holland DP,Hamilton CD,Weintrob AC,Engemann JJ,Fortenberry ER,Peloquin CA,Stout JE

更新日期：2009-05-01 00:00:00

abstract：:We reviewed the spectrum of activity, pharmacokinetics, clinical efficacy, adverse effects, and relative advantages of piperacillin-tazobactam, a new beta-lactam-beta-lactamase inhibitor. Piperacillin-tazobactam has a wide spectrum of activity that includes gram-positive organisms such as staphylococci and streptococc...

journal_title：Pharmacotherapy

authors： Daniel KP,Krop LC

更新日期：1996-03-01 00:00:00

abstract：:Struvite calculi result from urinary tract infections secondary to urease-producing bacteria. To prevent recurrent infection and stone formation complete removal of struvite calculi is recommended. Two illustrative reports of patients with renal struvite calculi are presented in which 10% hemiacidrin (Renacidin) irrig...

journal_title：Pharmacotherapy

authors： Massaro FJ,Weiner B,Sant GR,Meares EM Jr

更新日期：1983-11-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the prevalence, over 40 years, of using the last-observation-carried-forward (LOCF) imputation method in clinical trials, the association between use of LOCF and how the trials were conducted, and the extent of information about attrition and LOCF use in published reports. DESIGN:Retrospec...

journal_title：Pharmacotherapy

authors： Woolley SB,Cardoni AA,Goethe JW

更新日期：2009-12-01 00:00:00

abstract：:The purpose of the American College of Clinical Pharmacy (ACCP) is to advance human health by extending the frontiers of clinical pharmacy. Consistent with this mission and its core values, ACCP is committed to ensuring that clinical pharmacists possess the knowledge, skills, attitudes, and behaviors necessary to deli...

journal_title：Pharmacotherapy

authors： Saseen JJ,Ripley TL,Bondi D,Burke JM,Cohen LJ,McBane S,McConnell KJ,Sackey B,Sanoski C,Simonyan A,Taylor J,Vande Griend JP

更新日期：2017-05-01 00:00:00

abstract：:The pharmacokinetics of methylprednisolone sodium succinate (MPHS) and methylprednisolone (MP) were determined in six patients undergoing open heart surgery with cardiopulmonary bypass. Plasma concentrations of both compounds were measured by high-performance liquid chromatography after doses of MPHS of 1.7-2.4 g. The...

journal_title：Pharmacotherapy

authors： Kong AN,Jungbluth GL,Pasko MT,Beam TR,Jusko WJ

更新日期：1990-01-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) has become the most prevalent cause of acute hematogenous osteomyelitis (AHO) in pediatric patients. This increase in MRSA is due to the rise in community-acquired MRSA. Therefore, it is important that clinicians are aware of the various and upcoming therapies that co...

journal_title：Pharmacotherapy

authors： DeRonde KJ,Girotto JE,Nicolau DP

更新日期：2018-10-01 00:00:00

abstract：STUDY OBJECTIVE:To describe the pharmacokinetic disposition of tobramycin in children undergoing stem cell transplantation (SCT) after intravenous administration either every 24 hours or every 8 hours, and to use this information to create initial dosing guidelines for administration every 24 hours in this patient popu...

journal_title：Pharmacotherapy

authors： Dupuis LL,Sung L,Taylor T,Abdolell M,Allen U,Doyle J,Taddio A

更新日期：2004-05-01 00:00:00

abstract：:Cancer therapeutics is undergoing a revolution with the advent of new drugs that can selectively target molecules responsible for carcinogenesis and tumor growth. The type and mechanism of these targeting drugs vary. Some are small molecules that specifically target a binding site on a receptor or signal transduction ...

journal_title：Pharmacotherapy

authors： Jarkowski A 3rd,Glode AE,Spangenthal EJ,Wong MK

更新日期：2011-01-01 00:00:00

abstract：STUDY OBJECTIVE:To determine whether recommendations made by pharmacists and accepted by hospital physicians resulted in fewer postdischarge readmissions and urgent care visits compared with recommendations that were not implemented. DESIGN:Prospective substudy of pharmacist recommendations. SETTING:Tertiary care aca...

journal_title：Pharmacotherapy

authors： Anderegg SV,Demik DE,Carter BL,Dawson JD,Farris K,Shelsky C,Kaboli P

更新日期：2013-01-01 00:00:00

abstract：:We retrospectively reviewed the charts of 120 patients who received an initial prescription of iron from a resident physician in internal medicine to determine how accurately house officers diagnose iron-deficiency anemia before initiating iron therapy. Each patient's laboratory records were reviewed for the 3-month p...

journal_title：Pharmacotherapy

authors： Abernathy KA,Meuleman JR

更新日期：1996-05-01 00:00:00

abstract：:Nausea and vomiting are common complaints in the postoperative period and contribute to patient distress and delay of discharge for outpatient surgical procedures. Laparoscopic procedures are associated with a high incidence of postoperative nausea and vomiting (PONV) episodes. Parenteral use of metoclopramide prevent...

journal_title：Pharmacotherapy

authors： Wagner BK,Berman SL,Devitt PA,Halvorsen MB,O'Hara DA

更新日期：1996-11-01 00:00:00

abstract：:The antiretroviral combination of emtricitabine-tenofovir disoproxil fumarate (FTC/TDF) was approved by the U.S. Food and Drug Administration for use as pre-exposure prophylaxis (PrEP) in individuals at high risk for acquiring human immunodeficiency virus (HIV) in July 2012. Since then, Centers for Disease Control and...

journal_title：Pharmacotherapy

authors： Adams JL,Shelley K,Nicol MR

更新日期：2019-04-01 00:00:00

abstract：:Verapamil and diltiazem are effective in terminating paroxysmal supraventricular tachycardias and slowing ventricular response during atrial fibrillation or flutter. Results from clinical trials for each individual drug demonstrate comparative efficacy rates, and both drugs share the same contraindications and relativ...

journal_title：Pharmacotherapy

authors： Cheiman DM,Shea BF,Kelly RA

更新日期：1996-09-01 00:00:00

abstract：STUDY OBJECTIVES:To compare the antiemetic effectiveness and safety of oral granisetron plus dexamethasone with those of oral ondansetron plus dexamethasone administered before emetogenic chemotherapy. DESIGN:Randomized, prospective, multicenter, open-label study. SETTINGS:University-teaching hospital and veterans he...

journal_title：Pharmacotherapy

authors： Herrington JD,Kwan P,Young RR,Lagow E,Lagrone L,Riggs MW

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVES:To explore the illicit use of specific prescription stimulants among college students and add to our understanding of reasons (motives) and routes of administration associated with illicit use of these drugs. METHODS:A random sample of 4580 college students self-administered a Web-based survey. The survey c...

journal_title：Pharmacotherapy

authors： Teter CJ,McCabe SE,LaGrange K,Cranford JA,Boyd CJ

更新日期：2006-10-01 00:00:00

abstract：STUDY OBJECTIVES:To determine if low-dose lovastatin in combination with niacin causes a greater percentage reduction in low-density lipoprotein (LDL) cholesterol than lovastatin alone, and to determine if the combination increases the risk of serious adverse effects. design. Prospective, randomized, open-label, clinic...

journal_title：Pharmacotherapy

authors： Gardner SF,Schneider EF,Granberry MC,Carter IR

更新日期：1996-05-01 00:00:00

abstract：:Obesity is a worldwide epidemic often complicated by multiple comorbidities, including type 2 diabetes mellitus (T2DM). Bariatric surgery is an increasingly common and effective weight-loss strategy for obese patients that may result in resolution of metabolic-related disease states, such as T2DM. Although bariatric s...

journal_title：Pharmacotherapy

authors： Howard ML,Steuber TD,Nisly SA

更新日期：2018-06-01 00:00:00

abstract：:The efficacy of the sodium-glucose cotransporter 2 (SGLT2) inhibitors canagliflozin, dapagliflozin, and empagliflozin in reducing hyperglycemia in patients with type 2 diabetes is well documented. In addition, positive effects have been observed with these agents on nonglycemic variables, such as reductions in body we...

journal_title：Pharmacotherapy

authors： Trujillo JM,Nuffer WA

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The bispectral index (BIS), a processed variable derived from the raw electroencephalogram (EEG) used to guide sedation in the intensive care unit (ICU), has not been tested during barbiturate therapy for elevated intracranial pressure. We determined the BIS and suppression ratio (SR) values during traditiona...

journal_title：Pharmacotherapy

authors： Riker RR,Fraser GL,Wilkins ML

更新日期：2003-09-01 00:00:00

abstract：:A 43-year-old man with a 19-year history of Crohn's disease experienced serum sickness with acute lobular panniculitis and vasculitis within 2 weeks of initiating 6-mercaptopurine therapy. He had no history of extraintestinal manifestations of Crohn's disease or drug allergy. Symptoms included disabling joint pain, pr...

journal_title：Pharmacotherapy

authors： Andersen JM,Tiede JJ

更新日期：1997-01-01 00:00:00

abstract：:Atorvastatin calcium is an HMG-coenzyme A (CoA) reductase inhibitor that was approved by the Food and Drug Administration on December 17, 1996. Like other such agents, it inhibits the action of HMG-CoA reductase and thereby decreases endogenous cholesterol synthesis, leading to a decrease in circulating low-density li...

journal_title：Pharmacotherapy

authors： Chong PH,Seeger JD

更新日期：1997-11-01 00:00:00

abstract：STUDY OBJECTIVES:To determine changes in bone mineral density (BMD) and T scores of patients after 2 years of teriparatide therapy, and to determine the number of fractures that occurred during therapy. DESIGN:Prospective, observational study. SETTING:Pharmacist-run teriparatide clinic in a private-practice endocrino...

journal_title：Pharmacotherapy

authors： Stroup JS,Rivers SM,Abu-Baker AM,Kane MP

更新日期：2007-06-01 00:00:00

abstract：STUDY OBJECTIVE:To determine whether alvimopan for prevention of postoperative ileus in patients undergoing small- or large-bowel resection by laparotomy is associated with lower total costs compared with standard care. DESIGN:Pharmacoeconomic analysis using a formal decision model. DATA SOURCE:Four phase III clinica...

journal_title：Pharmacotherapy

authors： Touchette DR,Yang Y,Tiryaki F,Galanter WL

更新日期：2012-02-01 00:00:00

abstract：:Buspirone is the first of a new class of anxioselective agents, the azaspirodecanediones. It achieves peak serum concentrations within one hour and has a serum half-life of 2 to 5 hours. Animal studies have suggested antianxiety activity and the absence of abuse potential. Buspirone is both a dopamine agonist and anta...

journal_title：Pharmacotherapy

authors： Goldberg HL

更新日期：1984-11-01 00:00:00

abstract：STUDY OBJECTIVE:To compare the performance of polyclonal fluorescence polarization immunoassay (pFPIA) with that of enzyme-multiplied immunoassay technique (EMIT) in patients receiving vancomycin and hemodialysis. SETTING:Outpatient hemodialysis center. PATIENTS:Seven subjects with end-stage renal disease treated wit...

journal_title：Pharmacotherapy

authors： Kingery JR,Sowinski KM,Kraus MA,Klaunig JE,Mueller BA

更新日期：2000-06-01 00:00:00

abstract：:Fifteen percent of premenopausal women, 10-40% of postmenopausal women, and 10-25% of women receiving systemic hormone therapy experience urogenital atrophy. The most common symptoms are dryness, burning, pruritus, irritation, and dyspareunia. Estrogen loss, drugs, and chemical sensitivities are causes. Estrogen or ho...

journal_title：Pharmacotherapy

authors： Willhite LA,O'Connell MB

更新日期：2001-04-01 00:00:00