Serum sickness associated with 6-mercaptopurine in a patient with Crohn's disease.

Abstract:

:A 43-year-old man with a 19-year history of Crohn's disease experienced serum sickness with acute lobular panniculitis and vasculitis within 2 weeks of initiating 6-mercaptopurine therapy. He had no history of extraintestinal manifestations of Crohn's disease or drug allergy. Symptoms included disabling joint pain, proteinuria, fever, rash, and malaise. To our knowledge, this adverse drug reaction has not been described in association with 6-mercaptopurine.

journal_name

Pharmacotherapy

journal_title

Pharmacotherapy

authors

Andersen JM,Tiede JJ

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

173-6

issue

1

eissn

0277-0008

issn

1875-9114

journal_volume

17

pub_type

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