Evaluation of the half-life of intravenous human cytomegalovirus immune globulin in patients receiving partially mismatched related donor bone marrow transplantation.

abstract：:Apixaban, a direct factor Xa inhibitor, is a novel oral anticoagulant (NOAC) indicated for prevention of embolic events in patients with nonvalvular atrial fibrillation. The agent is associated with a lower risk of bleeding compared with vitamin K antagonists such as warfarin. Hemopericardium is a life-threatening ble...

journal_title：Pharmacotherapy

authors： Sigawy C,Apter S,Vine J,Grossman E

更新日期：2015-07-01 00:00:00

abstract：:Although in the last few years new antidepressants have become available in the United States, responses in many patients differ, from none, to partial, to delayed therapeutic response to the agents. If the antidepressant properties of these drugs could be enhanced or accelerated, it might be possible to improve patie...

journal_title：Pharmacotherapy

authors： Puzantian T,Kawase K

更新日期：1999-02-01 00:00:00

abstract：:Carbamazepine is a potent anticonvulsant agent with proven efficacy in the treatment of partial and tonic-clonic seizures. An epileptic child treated with therapeutic dosages of carbamazepine developed severe hepatitis and hepatic insufficiency. She had a positive response to withdrawal of the drug and administration ...

journal_title：Pharmacotherapy

authors： Morales-Diaz M,Pinilla-Roa E,Ruiz I

更新日期：1999-02-01 00:00:00

abstract：:A man anticoagulated with warfarin 57.5 mg/week (international normalized ratio [INR] 1.94) was diagnosed with nonsmall cell lung cancer and prescribed weekly gemcitabine. With the first dose of the first cycle, his INR rose to 3.52, and his weekly warfarin dose was decreased to 52.5 mg. The lower warfarin dose was co...

journal_title：Pharmacotherapy

authors： Kinikar SA,Kolesar JM

更新日期：1999-11-01 00:00:00

abstract：:We have developed a method for measuring the efficacy of a single dose of an analgesic for 12 hours after administration to outpatients with postoperative oral surgery pain. Using a self-rating record, patients evaluate their pain and its relief for 12 hours after medication. We have used this method successfully in a...

journal_title：Pharmacotherapy

authors： Beaver WT,Forbes JA,Shackleford RW

更新日期：1983-03-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the accuracy of four equations based on serum creatinine concentration-the original Schwartz equation and the Leger, Bedside Chronic Kidney Disease in Children (CKiD), and Counahan-Barratt equations-for determining glomerular filtration rate (GFR) in pediatric patients with chronic kidney di...

journal_title：Pharmacotherapy

authors： Lee CK,Swinford RD,Cerda RD,Portman RJ,Hwang W,Furth SL

更新日期：2012-07-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the effect of acarbose on glycemic control and glycemic variability, using a continuous glucose-monitoring system, in patients with type 2 diabetes mellitus who were not well controlled on metformin and vildagliptin therapy. DESIGN:Multicenter, randomized, double-blind, placebo-controlled s...

journal_title：Pharmacotherapy

authors： Derosa G,Franzetti I,Querci F,D'Angelo A,Maffioli P

更新日期：2015-11-01 00:00:00

abstract：:3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors are a frequently prescribed class of drugs that are generally well tolerated by most patients. A rare, yet serious side effect associated with these drugs is rhabdomyolysis. Although all HMG-CoA reductase inhibitors can cause this adverse effect, pre...

journal_title：Pharmacotherapy

authors： Ravnan SL,Locke C,Yee WP,Haase K

更新日期：2002-04-01 00:00:00

abstract：:A 12-year-old girl with cystic fibrosis was diagnosed with a high-grade glioma after radiographic and biopsy results confirmed the primary intracranial lesion. She was treated with single-agent erlotinib during and after daily localized radiation therapy. Pharmacokinetic studies were conducted to assess the effect of ...

journal_title：Pharmacotherapy

authors： Christiansen SR,Broniscer A,Panetta JC,Stewart CF

更新日期：2009-07-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the frequency of medication errors, as well as the severity of harm resulting from these errors, related to the prescription, transcription, preparation, and administration of parenteral nutrition formulations. DESIGN:Prospective, observational study. SETTING:471-bed, academic teaching ho...

journal_title：Pharmacotherapy

authors： Sacks GS,Rough S,Kudsk KA

更新日期：2009-08-01 00:00:00

abstract：:Levonorgestrel implants (Norplant) are an alternative to oral contraceptives and medroxyprogesterone acetate intramuscular injections. An interaction may exist between levonorgestrel and agents that induce the hepatic microsomal enzyme system. A 21-year-old woman with a history of a seizure disorder, treated with phen...

journal_title：Pharmacotherapy

authors： Shane-McWhorter L,Cerveny JD,MacFarlane LL,Osborn C

更新日期：1998-11-01 00:00:00

abstract：:Postoperative pain is one of the most common forms of acute pain. Optimal pain management decreases the stress response to surgery, reduces complications, improves recovery time, and results in improved economic and quality-of-life outcomes. A preoperative, multimodal approach to postoperative analgesia can be achieve...

journal_title：Pharmacotherapy

authors： Stephens JM,Pashos CL,Haider S,Wong JM

更新日期：2004-12-01 00:00:00

abstract：:Patients undergoing cardiopulmonary bypass may develop clinically significant physiologic alterations in the perioperative period, including alteration of thyroid hormone concentrations. Alterations in the concentration of thyroid hormones are of concern due to the effects of these hormones on cardiac function. Hypoth...

journal_title：Pharmacotherapy

authors： Reichert MG,Verzino KC

更新日期：2001-11-01 00:00:00

abstract：:A retrospective study evaluated the success of dosages of simvastatin lower than the 10-20 mg/day recommended by the manufacturer in patients with hypercholesterolemia. Records of 95 patients enrolled in a pharmacist-managed lipid clinic receiving stable dosages of simvastatin were reviewed. Data collected were demogr...

journal_title：Pharmacotherapy

authors： Rindone JP

更新日期：1999-04-01 00:00:00

abstract：:Colistin, the most widely used polymyxin antibiotic, was originally introduced in the late 1950s before the establishment of the present-day drug approval process. Originally shelved due to toxicity concerns, colistin, in the form of its inactive prodrug colistin methanesulfonate, has undergone a renaissance in the pa...

journal_title：Pharmacotherapy

authors： Ortwine JK,Kaye KS,Li J,Pogue JM

更新日期：2015-01-01 00:00:00

abstract：:The Internet is an excellent source of drug and poison information. Despite the relative case and minimal costs associated with accessing the Internet, many pharmacists and other health care professionals have been slow to adopt this new technology. ...

journal_title：Pharmacotherapy

authors： Marra CA,Lynd LD,McKerrow R,Carleton BC

更新日期：1996-07-01 00:00:00

abstract：:Meclofenamate sodium was compared, double-blind, with codeine and placebo for the treatment of acute episiotomy pain. One hundred sixty-eight women with moderate or severe episiotomy pain after normal delivery were assigned randomly to one of four treatment groups: one received meclofenamate sodium 200 mg at dose 1 an...

journal_title：Pharmacotherapy

authors： Hebertson RM,Storey N,Turner JL

更新日期：1986-09-01 00:00:00

abstract：:Many physiologic differences between children and adults can result in age-related differences in pharmacokinetics. Understanding the effects of age on bioavailability, volume of distribution, protein binding, hepatic metabolic isoenzymes, and renal elimination can provide insight into optimizing doses for pediatric p...

journal_title：Pharmacotherapy

authors： Anderson GD,Lynn AM

更新日期：2009-06-01 00:00:00

abstract：:Fatigue is one of the most debilitating and common symptoms associated with hematologic and oncologic disorders and treatment strategies. Patient factors influence etiology and symptom manifestation, which in turn affect diagnosis, management, and monitoring. Fatigue instruments can assist with the identification, man...

journal_title：Pharmacotherapy

authors： Schwartz AH

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Modification of guideline-directed medical therapy (GDMT) in hospitalized patients with heart failure (HF) has not been extensively evaluated. METHODS:The community surveillance arm of the Atherosclerosis Risk in Communities Study identified 6959 HF hospitalizations from 2005-2011. Predictors of GDMT modifi...

journal_title：Pharmacotherapy

authors： Tran RH,Aldemerdash A,Chang P,Sueta CA,Kaufman B,Asafu-Adjei J,Vardeny O,Daubert E,Alburikan KA,Kucharska-Newton AM,Stearns SC,Rodgers JE

更新日期：2018-04-01 00:00:00

abstract：:Cephalosporins are often administered to prevent infections that can follow total joint replacements (TJR) and other arthroplastic procedures. However, recommendations contained within published guidelines and review articles vary greatly from those given by the manufacturer in product information circulars. Similarly...

journal_title：Pharmacotherapy

authors： Heath AF

更新日期：1991-01-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the influence of withholding continuous enteral nutrition for 1 hour before and after warfarin administration compared with the coadministration of warfarin with continuous enteral nutrition on changes in international normalized ratios (INRs). DESIGN:Retrospective, crossover case series. SE...

journal_title：Pharmacotherapy

authors： Dickerson RN,Garmon WM,Kuhl DA,Minard G,Brown RO

更新日期：2008-03-01 00:00:00

abstract：:Neuroleptic malignant syndrome (NMS) is an idiosyncratic and uncommon but serious adverse effect that has been reported with both typical and atypical antipsychotic agents. We describe a 58-year-old man with Down syndrome and dementia who was receiving low-dose olanzapine and rivastigmine therapy; he developed NMS 4 m...

journal_title：Pharmacotherapy

authors： Stevens DL,Lee MR,Padua Y

更新日期：2008-03-01 00:00:00

abstract：:Among various forms of hearing loss, there are acute (within 72 hrs) or subacute (weeks to months) presentations that may be reversible with early pharmacological intervention. The workup of a patient presenting with hypoacusia includes the usual history and physical examination in conjunction with an audiometric asse...

journal_title：Pharmacotherapy

authors： Fazel MT,Jedlowski PM,Cravens RB Jr,Erstad BL

更新日期：2017-12-01 00:00:00

abstract：:Our objective was to describe the implementation and clinical outcomes of an employer-sponsored, pharmacist-provided medication therapy management (MTM) program for health plan beneficiaries with diabetes mellitus and/or hypertension. We conducted a single-center retrospective medical record review. The setting was a ...

journal_title：Pharmacotherapy

authors： Theising KM,Fritschle TL,Scholfield AM,Hicks EL,Schymik ML

更新日期：2015-11-01 00:00:00

abstract：STUDY OBJECTIVE:To determine whether recommendations made by pharmacists and accepted by hospital physicians resulted in fewer postdischarge readmissions and urgent care visits compared with recommendations that were not implemented. DESIGN:Prospective substudy of pharmacist recommendations. SETTING:Tertiary care aca...

journal_title：Pharmacotherapy

authors： Anderegg SV,Demik DE,Carter BL,Dawson JD,Farris K,Shelsky C,Kaboli P

更新日期：2013-01-01 00:00:00

abstract：:Nucleoside analogs (zidovudine, didanosine, zalcitabine, stavudine, abacavir, lamivudine) have been administered as antiretroviral agents for more than a decade. They undergo anabolic phosphorylation by intracellular kinases to form triphosphates, which inhibit human immunodeficiency virus replication by competitively...

journal_title：Pharmacotherapy

authors： Stein DS,Moore KH

更新日期：2001-01-01 00:00:00

abstract：:A 38-year-old woman with type 1 diabetes underwent kidney-pancreas transplantation. Her postoperative course was complicated due to recurrent acute graft rejections and pancreatitis. After initial immunosuppression with microemulsion cyclosporine, mycophenolate mofetil, and prednisone with muromonab-CD3 induction, cyc...

journal_title：Pharmacotherapy

authors： Min DI,Ku YM,Rayhill S,Corwin C,Wu YM,Hunsicker LG

更新日期：1999-07-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the relationship between impaired renal function and antifactor Xa activity in patients receiving dalteparin. DESIGN:Open-label prospective study. SETTING:Inpatient and outpatient units of a large teaching hospital. SUBJECTS:Eleven patients with renal impairment and 11 control subjects wi...

journal_title：Pharmacotherapy

authors： Shprecher AR,Cheng-Lai A,Madsen EM,Cohen HW,Sinnett MJ,Wong ST,Billett HH

更新日期：2005-06-01 00:00:00

abstract：:The prevalence of diabetes mellitus has grown to staggering numbers, and its incidence is expected to rise in the next 2 decades. The need for novel approaches to treat hyperglycemia cannot be ignored. Current agents have been shown to modestly improve glycemia and in some cases prevent complications of diabetes, but ...

journal_title：Pharmacotherapy

authors： Shah NK,Deeb WE,Choksi R,Epstein BJ

更新日期：2012-01-01 00:00:00