Abstract:
:Beta-blockers are an important cardiovascular drug class, recommended as first-line treatment of numerous diseases such as heart failure, hypertension, and angina, as well as treatment after myocardial infarction. However, responses to a beta-blocker are variable among patients. Results of numerous studies now suggest that genetic polymorphisms may contribute to variability in responses to beta-blockers. This review summarizes the pharmacogenetic data for beta-blockers in patients with various diseases and discusses the potential implications of beta-blocker pharmacogenetics in clinical practice.
journal_name
Pharmacotherapyjournal_title
Pharmacotherapyauthors
Shin J,Johnson JAdoi
10.1592/phco.27.6.874subject
Has Abstractpub_date
2007-06-01 00:00:00pages
874-87issue
6eissn
0277-0008issn
1875-9114journal_volume
27pub_type
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