Transient coagulation abnormalities after incompatible blood transfusion.

Abstract:

:This report describes an unusual hemolytic transfusion reaction. A group O donor was inadvertently transfused with 100 ml of group A red cells during the course of plasmapheresis. Granulocytopenia, thrombocytopenia, hypofibrinogenemia and low levels of factors V, VIII, and IX developed immediately after the infusion. The levels of the cellular elements and coagulation proteins returned to normal in less than an hour; too rapid for a de novo synthesis after consumption of coagulation proteins. We postulate that activation of the kinin system was responsible for the phenomena rather than intravascular coagulation with secondary fibrinolysis.

journal_name

Crit Care Med

journal_title

Critical care medicine

authors

McKenna PJ,Scheinman HZ

doi

10.1097/00003246-197501000-00003

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

8-12

issue

1

eissn

0090-3493

issn

1530-0293

journal_volume

3

pub_type

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