Complexity modeling: identify instability early.

abstract：OBJECTIVE:Pump-driven extracorporeal gas exchange systems have been advocated in patients suffering from severe acute respiratory distress syndrome who are at risk for life-threatening hypoxemia and/or hypercapnia. This requires extended technical and staff support. DESIGN:We report retrospectively our experience with...

journal_title：Critical care medicine

authors： Bein T,Weber F,Philipp A,Prasser C,Pfeifer M,Schmid FX,Butz B,Birnbaum D,Taeger K,Schlitt HJ

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:This study was designed to assess the effects on macrocirculation and microcirculation of adding an intra-aortic balloon pump to peripheral venoarterial extracorporeal membrane oxygenation in patients with severe cardiogenic shock and little/no residual left ventricular ejection. DESIGN:A prospective, singl...

journal_title：Critical care medicine

authors： Petroni T,Harrois A,Amour J,Lebreton G,Brechot N,Tanaka S,Luyt CE,Trouillet JL,Chastre J,Leprince P,Duranteau J,Combes A

更新日期：2014-09-01 00:00:00

abstract：:Transfusion-associated circulatory overload is the most frequent serious adverse transfusion reaction, with an incidence close to 1% of transfused patients in the general adult population. Patients in ICUs are probably more at risk of transfusion-associated circulatory overload as they are more frequently transfused a...

journal_title：Critical care medicine

authors： De Cloedt L,Savy N,Gauvin F,Taylor S,Lacroix J,Emeriaud G

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To describe the long-term health-related quality of life (HRQL) of survivors of sepsis and to evaluate the reliability and validity of the medical outcomes study Short Form-36 (SF-36) in this population. STUDY DESIGN:Cross-sectional survey. SETTING:University intensive care unit. PATIENTS:Surviving patient...

journal_title：Critical care medicine

authors： Heyland DK,Hopman W,Coo H,Tranmer J,McColl MA

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVES:Less than half of the thousands of children who suffer in-hospital cardiac arrests annually survive, and neurologic injury is common among survivors. Hemodynamic-directed cardiopulmonary resuscitation improves short-term survival, but its impact on longer term survival and mitochondrial respiration-a potenti...

journal_title：Critical care medicine

authors： Lautz AJ,Morgan RW,Karlsson M,Mavroudis CD,Ko TS,Licht DJ,Nadkarni VM,Berg RA,Sutton RM,Kilbaugh TJ

更新日期：2019-03-01 00:00:00

abstract：:The resolution time of pneumothorax in neonates requiring tube thoracotomy is not known. We found that 28%, 50%, and 83% of 54 pneumothoraces in 40 neonates resolved within 24, 96, and 168 h of tube thoracotomy, respectively. Pneumothoraces that persisted beyond 168 h were in infants requiring ventilatory assistance. ...

journal_title：Critical care medicine

authors： Bhatia J,Mathew OP

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:To study the course of gastric regional PCO2 (PrCO2) in patients with cardiogenic shock requiring intra-aortic balloon (IAB) counterpulsation and the prognostic value of PrCO2 in this patient population. DESIGN:A prospective, observational clinical study. SETTING:Medical intensive care unit in a university ...

journal_title：Critical care medicine

authors： Janssens U,Graf J,Koch KC,vom Dahl J,Hanrath P

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Addressing the quality gap in ICU-based palliative care is limited by uncertainty about acceptable models of collaborative specialist and generalist care. Therefore, we characterized the attitudes of physicians and nurses about palliative care delivery in an ICU environment. DESIGN:Mixed-methods study. SETT...

journal_title：Critical care medicine

authors： Wysham NG,Hua M,Hough CL,Gundel S,Docherty SL,Jones DM,Reagan O,Goucher H,Mcfarlin J,Cox CE

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The goals of this review article are to review the importance and value of standardized definitions in clinical research, as well as to propose the necessary tools and infrastructure needed to advance nosology and medial taxonomy to improve the quality of clinical trials in the field of critical care. DATA S...

journal_title：Critical care medicine

authors： Singh JM,Ferguson ND

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:The mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway is an essential component of innate immunity necessary for mediating proinflammatory responses in the setting of sepsis. We previously demonstrated that the mitogen-activated protein kinase 1/2 inhibitor trametinib pr...

journal_title：Critical care medicine

authors： Smith JA,Mayeux PR,Schnellmann RG

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to: 1) describe a newly mechanism of blood flow to the brain during cardiopulmonary resuscitation using the impedance threshold device in a piglet model of cardiac arrest, and 2) describe the survival benefits in humans of applying all of the highly recommended changes in the 2005...

journal_title：Critical care medicine

authors： Aufderheide TP,Alexander C,Lick C,Myers B,Romig L,Vartanian L,Stothert J,McKnite S,Matsuura T,Yannopoulos D,Lurie K

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:Light chains κ and λ are immunoglobulin constituents but also circulate independently in blood as free light chains. We investigated whether a concomitant abnormality in free light chain and immunoglobulin levels could identify a high risk of death sepsis subpopulation to inform future IV immunoglobulin tria...

journal_title：Critical care medicine

authors： Shankar-Hari M,Singer M,Spencer J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To describe critical illnesses that occur commonly in patients with human immunodeficiency virus (HIV) infection. METHODS:We reviewed and summarized the literature on critical illness in HIV infection using a computerized MEDLINE search. SUMMARY:In the last 10 yrs, our perception of HIV infection and acquir...

journal_title：Critical care medicine

authors： Rosen MJ,Narasimhan M

更新日期：2006-09-01 00:00:00

abstract：INTRODUCTION:Ventilator settings for patients with severe acute respiratory distress syndrome supported by venovenous extracorporeal membrane oxygenation are currently set arbitrarily. The impact on serum and pulmonary biotrauma markers of the transition to ultra-protective ventilation settings following extracorporeal...

journal_title：Critical care medicine

authors： Rozencwajg S,Guihot A,Franchineau G,Lescroat M,Bréchot N,Hékimian G,Lebreton G,Autran B,Luyt CE,Combes A,Schmidt M

更新日期：2019-11-01 00:00:00

abstract：:Total parenteral nutrition (TPN) increases CO2 production (VCO2) in patients on intermittent positive-pressure ventilation who cannot match their CO2 excretion to the CO2 load, leading to an increase in PaCO2. We studied gas exchange and blood gas values in six patients with chronic respiratory failure, who were venti...

journal_title：Critical care medicine

authors： Herve P,Simonneau G,Girard P,Cerrina J,Mathieu M,Duroux P

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Neurologic dysfunction, coma, and seizures are common in obstetric patients in the intensive care unit. OBJECTIVE:To review common neurologic disorders resulting in critical illness in pregnancy. REVIEW:Obstetric disorders causing coma and seizures include eclampsia, acute fatty liver of pregnancy, and amn...

journal_title：Critical care medicine

authors： Karnad DR,Guntupalli KK

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:Critical care ultrasonography has become established within ICUs as a diagnostic tool and to guide management strategies and practical procedures. Following an international consensus statement in 2011, various national professional societies and organizations have sought to develop and deliver training prog...

journal_title：Critical care medicine

authors： Wong A,Galarza L,Duska F

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:To create a novel tool to predict favorable neurologic outcomes during ICU stay among children with critical illness. DESIGN:Logistic regression models using adaptive lasso methodology were used to identify independent factors associated with favorable neurologic outcomes. A mixed effects logistic regressio...

journal_title：Critical care medicine

authors： Gupta P,Rettiganti M,Gossett JM,Daufeldt J,Rice TB,Wetzel RC

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:During cardiopulmonary resuscitation (CPR), elimination of CO2 was shown to be limited by low tissue perfusion, especially when very low perfusion pressures were generated. It has therefore been suggested that sodium bicarbonate (NaHCO3), by producing CO2, might aggravate the hypercarbic component of the exi...

journal_title：Critical care medicine

authors： Bar-Joseph G,Weinberger T,Castel T,Bar-Joseph N,Laor A,Bursztein S,Ben Haim S

更新日期：1998-08-01 00:00:00

abstract：:Right ventricular size and contractility were evaluated using two-dimensional echocardiography during the first days of respiratory support in 23 patients requiring mechanical ventilation for acute respiratory failure. Nine patients had normal echocardiographic right ventricular function, and nine other patients had a...

journal_title：Critical care medicine

authors： Jardin F,Gueret P,Dubourg O,Farcot JC,Margairaz A,Bourdarias JP

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVES:Muscle weakness associated with critical illness can be due to the illness itself, immobilization associated with it, and/or to concomitant use of drugs that affect neuromuscular transmission. This study investigated the contribution of immobilization per se to the muscle dysfunction, as well as the associat...

journal_title：Critical care medicine

authors： Ibebunjo C,Martyn JA

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:To characterize the landscape of process of care and safety outcomes for tracheal intubation across pediatric intensive care units BACKGROUND:Procedural process of care and safety outcomes of tracheal intubation across pediatric intensive care units has not been described. We hypothesize that the novel Nati...

journal_title：Critical care medicine

authors： Nishisaki A,Turner DA,Brown CA 3rd,Walls RM,Nadkarni VM,National Emergency Airway Registry for Children (NEAR4KIDS).,Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To determine if autopsies performed on patients who die in the medical intensive care unit (ICU) provide clinically important new information. DESIGN:Retrospective review. SETTING:A 16-bed medical-coronary ICU. PATIENTS:Patients who underwent autopsy during a 1-yr period. INTERVENTIONS:Pre mortem diagnose...

journal_title：Critical care medicine

authors： Blosser SA,Zimmerman HE,Stauffer JL

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of monoclonal antibody to tumor necrosis factor (TNF)-alpha on the hemodynamic alterations and survival rate in rats subjected to intestinal ischemia/reperfusion. DESIGN:Prospective, randomized study. SETTING:Animal laboratory of an institute for research in traumatology. SUBJECTS:M...

journal_title：Critical care medicine

authors： Yao YM,Bahrami S,Redl H,Schlag G

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:Oxygenation measured 24 hours after acute respiratory distress syndrome onset more accurately stratifies risk, relative to oxygenation at onset, in both children and adults. However, waiting 24 hours is problematic, especially for interventions that are more efficacious early in the disease course. We aimed t...

journal_title：Critical care medicine

authors： Yehya N,Thomas NJ,Khemani RG

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To compare measurement of cardiac output by the CO2 rebreathing method vs. the thermodilution cardiac output technique in the setting of acute respiratory failure in patients with chronic obstructive pulmonary disease. DESIGN:Prospective, comparative study of two methods in a consecutive sample. SETTING:Int...

journal_title：Critical care medicine

authors： Neviere R,Mathieu D,Riou Y,Guimez P,Renaud N,Chagnon JL,Wattel F

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:Sepsis results in organ dysfunction caused by a dysregulated host response, in part related to the immune response of a severe infection. Mesenchymal stromal cells are known to modulate the immune response, and expression of stromal cell-derived factor-1 regulates mobilization of neutrophils from the bone ma...

journal_title：Critical care medicine

authors： Kwon MY,Ghanta S,Ng J,Tsoyi K,Lederer JA,Bronson RT,El-Chemaly S,Chung SW,Liu X,Perrella MA

更新日期：2020-05-01 00:00:00

abstract：:The authors determined the correction factor (Ct) for three sizes of commonly available central venous catheters. These catheters are used as the injectate catheter when a 2.5 Fr transthoracic thermistor is used to determine cardiac output by thermodilution. The valves for Ct were highly reproducible. These determinat...

journal_title：Critical care medicine

authors： Baskoff JD,Maruschak GF

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVES:Low tidal volume (= tidal volume ≤ 6 mL/kg, predicted body weight) ventilation using volume control benefits patients with acute respiratory distress syndrome. Airway pressure release ventilation is an alternative to low tidal volume-volume control ventilation, but the release breaths generated are variable ...

journal_title：Critical care medicine

authors： Hirshberg EL,Lanspa MJ,Peterson J,Carpenter L,Wilson EL,Brown SM,Dean NC,Orme J,Grissom CK

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:The administration of vasopressin during cardiopulmonary resuscitation (CPR) provides significantly more vital organ blood flow when compared with epinephrine during cardiac arrest in pigs. The effects of this potent vasoconstrictor on postresuscitation cardiovascular function remain unknown. The purpose of t...

journal_title：Critical care medicine

authors： Prengel AW,Lindner KH,Keller A,Lurie KG

更新日期：1996-12-01 00:00:00