Antibiotic-Associated Apoptotic Enterocolitis in the Absence of a Defined Pathogen: The Role of Intestinal Microbiota Depletion.

abstract：BACKGROUND AND METHODS:We postulated that low-dose heparin (10 IU/kg.hr) administered as a continuous iv infusion may prevent or ameliorate the induction of thrombin-induced disseminated intravascular coagulation in baboons under general anesthesia. In a nonrandomized experiment lasting 8 hrs, animals were divided into...

journal_title：Critical care medicine

authors： du Toit HJ,Coetzee AR,Chalton DO

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:To review the incidence, diagnosis, and management of septic emboli caused by vascular catheters after surgery for congenital heart disease. DESIGN:Retrospective clinical review. All patients were computer registered. Our database includes daily follow-up and every sign of infection registered. SETTING:Pedi...

journal_title：Critical care medicine

authors： Erez E,Sharoni E,Ovadia B,Vidne BA,Dagan O

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:This report will describe the preparations for and the provision of care of two patients with Ebola virus disease in the biocontainment unit at the University of Nebraska Medical Center. DATA SOURCES:Patient medical records. STUDY SELECTION:Not applicable. DATA EXTRACTION:Not applicable. DATA SYNTHESIS:No...

journal_title：Critical care medicine

authors： Johnson DW,Sullivan JN,Piquette CA,Hewlett AL,Bailey KL,Smith PW,Kalil AC,Lisco SJ

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:Anaphylactic shock is associated with severe hypotension. Potassium channel blockers, such as 4-aminopyridine, induce vasoconstriction. The objective of this study was to test the ability of 4-aminopyridine to restore blood pressure and increase survival in anaphylactic shock. DESIGN:Experimental study. SE...

journal_title：Critical care medicine

authors： Bellou A,Al-Hammadi S,Aburawi EH,Dhanasekaran S,Nemmar A,Oulhaj A,Shafiuallah M,Zerrouki M,Yasin J,Bellou L,Alper SL,Bellou S,Kazzam E

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Exosomes are small, cell-released vesicles (40-100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) too...

journal_title：Critical care medicine

authors： Terrasini N,Lionetti V

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Microcirculatory alterations are associated with adverse outcome in subsets of critically ill patients. The prevalence and significance of microcirculatory alterations in the general ICU population are unknown. We studied the prevalence of microcirculatory alterations in a heterogeneous ICU population and it...

journal_title：Critical care medicine

authors： Vellinga NA,Boerma EC,Koopmans M,Donati A,Dubin A,Shapiro NI,Pearse RM,Machado FR,Fries M,Akarsu-Ayazoglu T,Pranskunas A,Hollenberg S,Balestra G,van Iterson M,van der Voort PH,Sadaka F,Minto G,Aypar U,Hurtado FJ,Mar

更新日期：2015-01-01 00:00:00

abstract：:Critical Care Medicine encompasses an extremely broad scope. Examination questions were, therefore, chosen to cover a wide variety of critical care topics. A near Gaussian distribution of scores was found for all physician groups studied. We believe the low mean score of 15% reflects the general difficulty of the exam...

journal_title：Critical care medicine

authors： Veremakis C,Taylor RW

更新日期：1983-05-01 00:00:00

abstract：OBJECTIVE:To provide a comprehensive review of the issue related to the administration of sedative, analgesic, and neuromuscular blocking agents (NMBA) to patients who are receiving ventilatory support for acute respiratory distress syndrome (ARDS) with high-frequency oscillatory ventilation. RESULTS:Sedative, analges...

journal_title：Critical care medicine

authors： Sessler CN

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of routine intensive care unit surveillance compared with frequent 12-lead electrocardiogram monitoring for detecting electrocardiogram evidence suggestive of prolonged myocardial ischemia in vascular surgery patients. DESIGN:Prospective cohort trial. SETTING:Intensive care unit....

journal_title：Critical care medicine

authors： Martinez EA,Kim LJ,Faraday N,Rosenfeld B,Bass EB,Perler BA,Williams GM,Dorman T,Pronovost PJ

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to test the hypothesis that the right ventricle is more dilated during resuscitation from cardiac arrest caused by pulmonary embolism, compared with hypoxia and primary arrhythmia. DESIGN:Twenty-four pigs were anesthetized and cardiac arrest was induced using three different method...

journal_title：Critical care medicine

authors： Aagaard R,Caap P,Hansson NC,Bøtker MT,Granfeldt A,Løfgren B

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of norepinephrine on static (right atrial pressure, pulmonary artery occlusion pressure ) and dynamic (pulse pressure variation and arterial systolic pressure variation) preload indicators in experimental hemorrhagic shock. DESIGN:Prospective controlled experimental study. SETTING:...

journal_title：Critical care medicine

authors： Nouira S,Elatrous S,Dimassi S,Besbes L,Boukef R,Mohamed B,Abroug F

更新日期：2005-10-01 00:00:00

abstract：:High-risk patients who survived general (noncardiac) surgery were observed to have cardiac index (CI) values averaging 4.5 L/min.m2, oxygen delivery (DO2) greater than 600 ml/min.m2, and oxygen consumption (VO2) 170 ml/min.m2 during the first 2 or three days postoperatively. Patients who subsequently died maintained r...

journal_title：Critical care medicine

authors： Shoemaker WC,Kram HB,Appel PL

更新日期：1990-01-01 00:00:00

abstract：:Conventional wisdom suggests that the "human factor" in critical care environments is reason for inadequate medication and patient safety. "Human factors" (or human factors engineering) is also a scientific discipline and practice of improving human performance. Using decades of human factors research, this paper eval...

journal_title：Critical care medicine

authors： Scanlon MC,Karsh BT

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND AND METHODS:Twelve adult male albino rabbits were assigned alternately to normotensive and hypotensive groups to assess the effect of hypovolemic shock on spontaneous correction of dilutional coagulopathy. All animals underwent dilutional exchange transfusion with 200 mL of rabbit RBCs and 5% human albumin. ...

journal_title：Critical care medicine

authors： Hewson JR,Prodger D,Roberts RS,Davis C,Fuller HD,Gregor P,Thomas EJ,Shragge BW,Russett J,Neame PB

更新日期：1991-02-01 00:00:00

abstract：:Bed rest is frequently prescribed for critically ill patients because it is assumed to be beneficial for preventing complications, for conserving scarce metabolic resources, and for providing patient comfort. Furthermore, higher levels of physical activity in critically ill patients have been assumed to be impractical...

journal_title：Critical care medicine

authors： Brower RG

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Acute aneurysmal subarachnoid hemorrhage (SAH) is a complex multifaceted disorder that plays out over days to weeks. Many patients with SAH are seriously ill and require a prolonged intensive care unit stay. Cardiopulmonary complications are common. The management of patients with SAH focuses on the anticipat...

journal_title：Critical care medicine

authors： Diringer MN

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the lectin-like domain of tumor necrosis factor, mimicked by the TIP peptide, can improve lung function after unilateral orthotopic lung isotransplantation. Because of a lack of a specific treatment for ischemia reperfusion-mediated lung injury, accompanied by a disrupted barrier i...

journal_title：Critical care medicine

authors： Hamacher J,Stammberger U,Roux J,Kumar S,Yang G,Xiong C,Schmid RA,Fakin RM,Chakraborty T,Hossain HM,Pittet JF,Wendel A,Black SM,Lucas R

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To describe three female patients of one family with different phenotypes of the same mutation of the ornithine transcarbamylase gene. X-linked inherited ornithine transcarbamylase deficiency is the most frequent urea cycle disorder. Many of the hemizygous males die during the neonatal period. Women, who are ...

journal_title：Critical care medicine

authors： Legras A,Labarthe F,Maillot F,Garrigue MA,Kouatchet A,Ogier de Baulny H

更新日期：2002-01-01 00:00:00

abstract：:To achieve synchronized differential pulmonary ventilation, an Ohio 560 ventilator was modified through separation of the outputs of the deep breath bellows and the tidal volume bellows and providing independent volume, flow rate, PEEP, oxygen-humidification, and alarm systems. The described ventilator modification is...

journal_title：Critical care medicine

authors： Popovich J Jr,Sanders OJ Jr,Vij D,Polanski JJ,Conway WA

更新日期：1981-06-01 00:00:00

abstract：:Transcutaneous PO2 (PtcO2), PaO2, PtcO2 arterial index (ARI; PtcO2/PaO2), and the initial slope index (ISI; [delta PO2/min]/starting PtcO2) were measured in 42 healthy volunteers, 12 patients with stable circulation and respiratory insufficiency, and ten patients with insufficient peripheral circulation in cardiogenic...

journal_title：Critical care medicine

authors： Lemke R,Klaus D,Lübbers DW,Oevermann G

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:To determine the influence of a selective, sterile central nervous system surgery on immune reactivity, particularly whether a decrease of monocytic human leukocyte antigen-DR expression, indicating immunodepression, occurs after neurosurgery and if this measurement is useful for identification of patients wi...

journal_title：Critical care medicine

authors： Asadullah K,Woiciechowsky C,Döcke WD,Liebenthal C,Wauer H,Kox W,Volk HD,Vogel S,Von Baehr R

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To examine the frequency of obtaining Institutional Review Board (IRB) approval and informed consent in critical care research. DATA SOURCES AND DATA EXTRACTION:One-year retrospective review of original critical care research in humans published in seven journals, including American Journal of Respiratory an...

journal_title：Critical care medicine

authors： Matot I,Pizov R,Sprung CL

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Neutropenia recovery may be associated with an increased risk of respiratory function deterioration. A history of pneumonia complicating neutropenia has been identified as the leading cause of adult respiratory distress syndrome during neutropenia recovery in patients receiving anticancer chemotherapy, sugges...

journal_title：Critical care medicine

authors： Azoulay E,Attalah H,Yang K,Herigault S,Jouault H,Brun-Buisson C,Brochard L,Harf A,Schlemmer B,Delclaux C

更新日期：2003-01-01 00:00:00

abstract：:Pentoxifylline has been shown to increase red blood cell malleability, thus increasing capillary blood flow in a number of disease states. The present study was undertaken to determine whether pentoxifylline might improve tissue oxygenation after anesthesia and during an operation in rats. Rats were anesthetized and d...

journal_title：Critical care medicine

authors： Soliman MH,O'Neal K,Waxman K

更新日期：1987-02-01 00:00:00

abstract：OBJECTIVES:Interventions that reduce the generation or the effects of reactive oxygen species exert controversial effects in animal models of lung injury, and these could be secondary to the pro-oxidant effects of antioxidants generally by their interaction with iron. We here describe the effects of N-acetylcysteine, d...

journal_title：Critical care medicine

authors： Ritter C,da Cunha AA,Echer IC,Andrades M,Reinke A,Lucchiari N,Rocha J,Streck EL,Menna-Barreto S,Moreira JC,Dal-Pizzol F

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the occurrence of complications and patient deteriorations during the air and ground transportation of intubated pediatric patients, performed by a nonphysician-based team under the direction of an intensive care attending physician or fellow. DESIGN:Retrospective chart review. SETTING:A 600-bed...

journal_title：Critical care medicine

authors： Beyer AJ 3rd,Land G,Zaritsky A

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:To compare the results of cardiac output measurements obtained by lithium dilution and thermodilution. DESIGN:Case series, observational study. SETTING:High-dependency postoperative unit and intensive care unit of a teaching hospital. PATIENTS:Forty patients were studied. Thirty-four patients had undergoin...

journal_title：Critical care medicine

authors： Linton R,Band D,O'Brien T,Jonas M,Leach R

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:Transarterial chemoembolization is a widely used therapy for the treatment of hepatocellular carcinoma. A rare adverse event is acute respiratory distress syndrome from pulmonary embolization of Lipiodol, an iodinated oil commonly used during the procedure. The objective of this report is to describe an atypi...

journal_title：Critical care medicine

authors： Taupin D,Mukherjee V,Nathavitharana R,Green DA,Fridman D

更新日期：2014-06-01 00:00:00

abstract：:Trauma is the leading cause of both morbidity and mortality in the pediatric population, and traumatic injury causes > 50% of all childhood deaths. Significant mortality rates have been reported for children with traumatic brain injury. Although children have better survival rates as compared with adults with traumati...

journal_title：Critical care medicine

authors： Mazzola CA,Adelson PD

更新日期：2002-11-01 00:00:00

abstract：:Utilizing a well-established porcine model of cardiac arrest, we found that end-tidal CO2 concentration (ETCO2) strikingly decreased to approximately 24% of control levels, immediately after cardiac arrest and before precordial compression. During precordial compression, ETCO2 progressively increased to 46% of control...

journal_title：Critical care medicine

authors： Trevino RP,Bisera J,Weil MH,Rackow EC,Grundler WG

更新日期：1985-11-01 00:00:00