Critical care management of head trauma in children.

abstract：OBJECTIVES:Corticosteroid therapy is frequently used in septic patients given the rationale that there is an increased demand for corticosteroid in sepsis, and up to 60% of severe septic patients experience adrenal insufficiency. However, the efficacy of corticosteroid therapy and whether the therapy should be based on...

journal_title：Critical care medicine

authors： Ai J,Guo L,Zheng Z,Wang SX,Huang B,Li XA

更新日期：2015-11-01 00:00:00

abstract：:The current definition of sepsis is life-threatening, acute organ dysfunction secondary to a dysregulated host response to infection. Criteria to operationalize this definition can be judged by six domains of usefulness (reliability, content, construct and criterion validity, measurement burden, and timeliness). The r...

journal_title：Critical care medicine

authors： Seymour CW,Coopersmith CM,Deutschman CS,Gesten F,Klompas M,Levy M,Martin GS,Osborn TM,Rhee C,Warren DK,Watson RS,Angus DC

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To review the rationale for the regionalization of adult critical care and discuss how lessons from the trauma experience may be relevant to this debate. DESIGN:Narrative review and opinion. RESULTS:Variation in the quality of critical care among hospitals has prompted calls for regionalization of care for ...

journal_title：Critical care medicine

authors： Kahn JM,Branas CC,Schwab CW,Asch DA

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Neutropenia recovery may be associated with an increased risk of respiratory function deterioration. A history of pneumonia complicating neutropenia has been identified as the leading cause of adult respiratory distress syndrome during neutropenia recovery in patients receiving anticancer chemotherapy, sugges...

journal_title：Critical care medicine

authors： Azoulay E,Attalah H,Yang K,Herigault S,Jouault H,Brun-Buisson C,Brochard L,Harf A,Schlemmer B,Delclaux C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:Despite having dysregulated iron metabolism, critically ill patients may receive exogenous iron for the treatment of anemia. Iron is associated with increased tissue apoptosis and may facilitate bacterial growth. We hypothesized that exogenous iron administration given after the onset of sepsis would lead to...

journal_title：Critical care medicine

authors： Javadi P,Buchman TG,Stromberg PE,Husain KD,Dunne WM,Woolsey CA,Turnbull IR,Hotchkiss RS,Karl IE,Coopersmith CM

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:To define the hemodynamic and gastric intramucosal PCO2 (PiCO2) changes during the first 48 hrs after burn trauma and to analyze their relationship with outcome. DESIGN:Prospective, observational study in a cohort of consecutively admitted critically ill burn patients. SETTING:Intensive care burn unit in a...

journal_title：Critical care medicine

authors： Lorente JA,Ezpeleta A,Esteban A,Gordo F,de la Cal MA,Díaz C,Arévalo JM,Tejedor C,Pascual T

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVES:To outline the concepts involved in optimizing antibacterial dosing in critically ill patients with acute renal failure undergoing continuous renal replacement therapy (CRRT), provide a strategy for optimizing dosing, and summarize the data required to implement the strategy. DATA SOURCES:MEDLINE search fro...

journal_title：Critical care medicine

authors： Choi G,Gomersall CD,Tian Q,Joynt GM,Freebairn R,Lipman J

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:Our first objective was to determine a blood lactate threshold predictive of survival in human immunodeficiency virus patients experiencing lactic acidosis related to nucleoside analogs, and second, to test l-carnitine for the treatment of patients exceeding that threshold. DESIGN:a) Retrospective study usin...

journal_title：Critical care medicine

authors： Claessens YE,Cariou A,Monchi M,Soufir L,Azoulay E,Rouges P,Goldgran-Toledano D,Branche F,Dhainaut JF

更新日期：2003-04-01 00:00:00

abstract：:Because determining cardiac output is difficult in premature infants, little is known about the hemodynamic effects of PEEP in this age group. We used pulsed-wave Doppler echocardiography to assess the hemodynamic effects of PEEP increments in ten premature infants with respiratory distress syndrome. At a PEEP of 4 cm...

journal_title：Critical care medicine

authors： Hausdorf G,Hellwege HH

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:Intrahospital transport of critically ill patients is often necessary for optimal patient care. However, transport of intensive care unit (ICU) patients within the hospital has been associated with a high rate of potentially detrimental complications. This study was designed to determine the occurrence rate o...

journal_title：Critical care medicine

authors： Szem JW,Hydo LJ,Fischer E,Kapur S,Klemperer J,Barie PS

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:To determine the association of pulmonary artery catheter (PAC) use with in-hospital mortality. DESIGN:Prospective, observational study. SETTING:The medical intensive care units (MICU) of two teaching hospitals. METHODS:The study included 751 adults who were admitted to the MICU, excluding those who stayed...

journal_title：Critical care medicine

authors： Afessa B,Spencer S,Khan W,LaGatta M,Bridges L,Freire AX

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:Extracellular mitochondrial DNA and N-formyl peptides released following tissue damage may contribute to systemic inflammation through stimulation of the innate immune system. In this review, we evaluate existing in vivo human data regarding a role for mitochondrial DNA and N-formyl peptides in producing sys...

journal_title：Critical care medicine

authors： Lubkin DT,Bishawi M,Barbas AS,Brennan TV,Kirk AD

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To determine whether the absence or presence of clinical pharmacists in intensive care units (ICUs) results in differences in mortality rates, length of ICU stay, and ICU charges for Medicare patients with nosocomial-acquired infections, community-acquired infections, and sepsis. DESIGN, SETTING, AND PATIENT...

journal_title：Critical care medicine

authors： MacLaren R,Bond CA,Martin SJ,Fike D

更新日期：2008-12-01 00:00:00

abstract：:Pulmonary barotrauma developed in 18/430 patients receiving respirator support for longer than 12 hours. Pneumothorax occurred in 15 of these patients and was treated with tube thoracostomy and 15-20 cm H2O pleural suction. Full reexpansion of the lungs were achieved in all but three patients, two of whom had bronchop...

journal_title：Critical care medicine

authors： Zimmerman JE,Dunbar BS,Klingenmaier CH

更新日期：1975-03-01 00:00:00

abstract：OBJECTIVE:We hypothesized that the extent of injury and release of xanthine oxidase, an oxidant generator, into the circulation would be less in normal-flow hypoxia-reoxygenation than in equal duration no-flow ischemia-reperfusion. DESIGN:Randomized study. SETTING:University-based animal research facility. SUBJECTS:...

journal_title：Critical care medicine

authors： Tan S,Yokoyama Y,Wang Z,Zhou F,Nielsen V,Murdoch AD,Adams C,Parks DA

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:The neuroprotective effects of the noble gas xenon are well known. Argon, in contrast to xenon, is abundant, inexpensive, and therefore widely applicable. In this study, we analyzed the possible neuroprotective role of argon in an in vivo rat model of acute focal cerebral ischemia. DESIGN:Controlled laborato...

journal_title：Critical care medicine

authors： Ryang YM,Fahlenkamp AV,Rossaint R,Wesp D,Loetscher PD,Beyer C,Coburn M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a bolus infusion of diaspirin cross-linked hemoglobin (DCLHb or hemoglobin crosfumaril) on the ileal mucosal microcirculation in septic rats. DESIGN:Prospective, randomized, single-blinded study. SETTING:University-affiliated animal research laboratory. SUBJECTS:Twenty-four male ...

journal_title：Critical care medicine

authors： Sielenkämper AW,Eichelbrönner O,Martin CM,Madorin SW,Chin-Yee IH,Sibbald WJ

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVES:During cardiopulmonary resuscitation (CPR), elimination of CO2 was shown to be limited by low tissue perfusion, especially when very low perfusion pressures were generated. It has therefore been suggested that sodium bicarbonate (NaHCO3), by producing CO2, might aggravate the hypercarbic component of the exi...

journal_title：Critical care medicine

authors： Bar-Joseph G,Weinberger T,Castel T,Bar-Joseph N,Laor A,Bursztein S,Ben Haim S

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:In patients undergoing surgical repair of aortic dissection, false lumen perfusion during cardiopulmonary bypass may produce central nervous system damage, myocardial ischemia, aortic rupture, and death. We describe a method to detect false lumen perfusion at the beginning of retrograde aortic perfusion that ...

journal_title：Critical care medicine

authors： Voci P,Testa G,Tritapepe L,Menichetti A,Caretta Q

更新日期：2000-06-01 00:00:00

abstract：:The relationship between oxygen uptake (Vo2) and delivery (Do2) was examined in 64 patients immediately after cardiopulmonary bypass. In 44 patients with lactate levels below 2.5 mmol/L, Vo2 decreased proportionally when Do2 decreased below 300 ml/min X m2. At a Do2 over this level, Vo2 plateaued at 105 +/- 13 (SD) ml...

journal_title：Critical care medicine

authors： Komatsu T,Shibutani K,Okamoto K,Kumar V,Kubal K,Sanchala V,Lees DE

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVES:In-hospital pediatric sepsis mortality has decreased substantially, but long-term mortality and morbidity among children initially surviving sepsis, is unknown. Accordingly, the Life After Pediatric Sepsis Evaluation investigation was conducted to describe the trajectory of mortality and health-related quali...

journal_title：Critical care medicine

authors： Zimmerman JJ,Banks R,Berg RA,Zuppa A,Newth CJ,Wessel D,Pollack MM,Meert KL,Hall MW,Quasney M,Sapru A,Carcillo JA,McQuillen PS,Mourani PM,Wong H,Chima RS,Holubkov R,Coleman W,Sorenson S,Varni JW,McGalliard J,Haal

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To compare prone positioning and continuous rotational therapy with respect to oxygenation and hemodynamics in patients suffering from adult respiratory distress syndrome (ARDS). DESIGN:Randomized, prospective pilot study. SETTING:Intensive care unit at a university hospital. PATIENTS:Twenty-six mechanical...

journal_title：Critical care medicine

authors： Staudinger T,Kofler J,Müllner M,Locker GJ,Laczika K,Knapp S,Losert H,Frass M

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Although hepatic cytochrome P-450 protein concentrations are altered following endotoxin shock, changes in P-450 isoforms in sepsis have not been fully investigated. The aim of this study was to determine whether the major P-450 isoform in rat liver (i.e., CYP1A2) is down-regulated during the progression of s...

journal_title：Critical care medicine

authors： Crawford JH,Yang S,Zhou M,Simms HH,Wang P

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of bulk diffusion in maintaining oxygenation during apnea testing for brain death. DESIGN:Case series. SETTING:ICU in a primary care hospital. PATIENTS:Twenty-four consecutive patients with suspected brain death. Most patients suffered cerebral trauma from vehicular accidents. INTER...

journal_title：Critical care medicine

authors： al Jumah M,McLean DR,al Rajeh S,Crow N

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To assess the effect of a helium-oxygen mixture on intubation rate and clinical outcomes during noninvasive ventilation in acute exacerbation of chronic obstructive pulmonary disease. DESIGN:Multicenter, prospective, randomized, controlled trial. SETTING:Seven intensive care units. PATIENTS:A total of 204 ...

journal_title：Critical care medicine

authors： Maggiore SM,Richard JC,Abroug F,Diehl JL,Antonelli M,Sauder P,Mancebo J,Ferrer M,Lellouche F,Lecourt L,Beduneau G,Brochard L

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:Lung CT is the reference imaging technique for acute respiratory distress syndrome, but requires transportation outside the intensive care and x-ray exposure. Lung ultrasound is a promising, inexpensive, radiation-free, tool for bedside imaging. Aim of the present study was to compare the global and regional...

journal_title：Critical care medicine

authors： Chiumello D,Umbrello M,Sferrazza Papa GF,Angileri A,Gurgitano M,Formenti P,Coppola S,Froio S,Cammaroto A,Carrafiello G

更新日期：2019-11-01 00:00:00

abstract：:To determine whether end-tidal carbon dioxide tension (PETCO2) accurately reflects PaCO2 during high-frequency jet ventilation (HFJV), 43 studies were performed on eight mongrel dogs with normal lungs. During HFJV, minute volume was modified to obtain a range of PaCO2 values from 15.5 to 74.5 torr. When PETCO2 was mea...

journal_title：Critical care medicine

authors： Algora-Weber A,Rubio JJ,Dominguez de Villota E,Cortes JL,Gomez D,Mosquera JM

更新日期：1986-10-01 00:00:00

abstract：:Oral amiodarone's slow absorption handicaps rapid treatment of life-threatening arrhythmias. We used iv amiodarone to treat ten patients with hemodynamically significant atrial arrhythmias and life-threatening ventricular arrhythmias refractory to all conventional medical treatment. Arrhythmias were controlled in nine...

journal_title：Critical care medicine

authors： Alves LE,Rose EP,Cahill TB Jr

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:To assess protective and risk factors for mortality among pediatric patients during initial care after hematopoietic stem cell transplantation (HSCT) and to evaluate changes in hospital mortality. DESIGN:Retrospective cohort using the 1997, 2000, and 2003 Kids Inpatient Database, a probabilistic sample of ch...

journal_title：Critical care medicine

authors： Bratton SL,Van Duker H,Statler KD,Pulsipher MA,McArthur J,Keenan HT

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:Recent in vivo studies of both septic humans and animals demonstrate that leukocyte delivery is attenuated to sites remote from the primary infection. The mechanisms for this are not entirely clear. L-selectin is integral to rolling, the first step in leukocyte recruitment to an inflammatory site. L-selectin ...

journal_title：Critical care medicine

authors： Ferri LE,Swartz D,Christou NV

更新日期：2001-01-01 00:00:00