Management of subcutaneous emphysema, pneumomediastinum, and pneumothorax during respirator therapy.

abstract：OBJECTIVES:The aim of this study was to evaluate the relative frequency of pediatric in-hospital cardiopulmonary resuscitation events occurring in ICUs compared to general wards. We hypothesized that the proportion of pediatric cardiopulmonary resuscitation provided in ICUs versus general wards has increased over the p...

journal_title：Critical care medicine

authors： Berg RA,Sutton RM,Holubkov R,Nicholson CE,Dean JM,Harrison R,Heidemann S,Meert K,Newth C,Moler F,Pollack M,Dalton H,Doctor A,Wessel D,Berger J,Shanley T,Carcillo J,Nadkarni VM,Eunice Kennedy Shriver National Institute

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:This pilot study was designed to identify which contextual factors facilitate/hinder the implementation of the awakening, breathing, coordination, delirium, and early mobility (ABCDE) bundle for guidance in future studies. DESIGN:The sources of data for this study included document review, planned site visit...

journal_title：Critical care medicine

authors： Carrothers KM,Barr J,Spurlock B,Ridgely MS,Damberg CL,Ely EW

更新日期：2013-09-01 00:00:00

abstract：:Colloid osmotic pressure (COP) was measured simultaneously with cardiorespiratory measurements in 103 surgical patients suspected of having circulatory problems. In a small subset of 28 patients, measurements were taken before, during, and after surgical operations. Similarly, data sets were taken before, during, and ...

journal_title：Critical care medicine

authors： Shippy CR,Shoemaker WC

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:To determine whether four stages of weaning (acute, prewean, wean, and outcome) could be identified by using clinical instruments designed to quantify severity of illness, patient stability, or weaning readiness. The instruments used were the Acute Physiology and Chronic Health Evaluation (APACHE III), the Th...

journal_title：Critical care medicine

authors： Burns SM,Ryan B,Burns JE

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:The requirement for a blood transfusion after trauma is associated with an increased risk of acute lung injury. Residual leukocytes contaminating red cells are potential mediators of this syndrome. The goal of this trial was to test our hypothesis that prestorage leukoreduction of blood would reduce rates of ...

journal_title：Critical care medicine

authors： Watkins TR,Rubenfeld GD,Martin TR,Nester TA,Caldwell E,Billgren J,Ruzinski J,Nathens AB

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:To assess whether sepsis-associated coagulopathy predicts hospital mortality. DESIGN:Retrospective cohort study. SETTING:One-thousand three-hundred beds urban academic medical center. PATIENTS:Six-thousand one-hundred forty-eight consecutive patients hospitalized between January 1, 2010, and December 31, ...

journal_title：Critical care medicine

authors： Lyons PG,Micek ST,Hampton N,Kollef MH

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Increasing evidence, including publication of the Transfusion Requirements in Critical Care trial in 1999, supports a lower hemoglobin threshold for RBC transfusion in ICU patients. However, little is known regarding the influence of this evidence on clinical practice over time in a large population-based coh...

journal_title：Critical care medicine

authors： Murphy DJ,Needham DM,Netzer G,Zeger SL,Colantuoni E,Ness P,Pronovost PJ,Berenholtz SM

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To define a biomarker panel to predict organ dysfunction, shock, and in-hospital mortality in emergency department (ED) patients with suspected sepsis. DESIGN:Prospective observational study. SETTING:EDs of ten academic medical centers. PATIENTS:There were 971 patients enrolled. INCLUSION CRITERIA:1) ED p...

journal_title：Critical care medicine

authors： Shapiro NI,Trzeciak S,Hollander JE,Birkhahn R,Otero R,Osborn TM,Moretti E,Nguyen HB,Gunnerson KJ,Milzman D,Gaieski DF,Goyal M,Cairns CB,Ngo L,Rivers EP

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Critically ill patients routinely receive vancomycin as empiric antibiotic therapy. A continuous infusion administration strategy may be superior to intermittent infusion by minimizing peak concentrations and variability thereby optimizing safety. We performed a systematic review and meta-analysis to investi...

journal_title：Critical care medicine

authors： Flannery AH,Bissell BD,Bastin MT,Morris PE,Neyra JA

更新日期：2020-06-01 00:00:00

abstract：:Fifteen patients with septic shock and perfusion failure received a 20-min infusion of glucose-insulin-potassium (GIK, glucose 50%, 1 g/kg body weight; insulin 1.5 U/kg, potassium, 10 mMol) after volume loading and vasoactive medication had failed to eliminate hypotension and lactacidemia. Hemodynamic and oxygen measu...

journal_title：Critical care medicine

authors： Bronsveld W,van den Bos GC,Thijs LG

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:To discuss a possible role of the endothelium in sepsis. DATA SOURCES:Studies published in biomedical journals and our own experimental results. STUDY SELECTION:Studies on endothelial mechanisms in the context of sepsis. DATA EXTRACTION AND SYNTHESIS:Changes in endothelial cells on activation by inflammato...

journal_title：Critical care medicine

authors： Hack CE,Zeerleder S

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To review the institutional experience of a national tertiary referral center for extracorporeal life support (ECLS) in severe varicella pneumonia. DATA SOURCES:Hospital records and ECLS flow sheets. STUDY SELECTION:All pediatric (nonneonatal) and adult patients who were treated for varicella pneumonia with...

journal_title：Critical care medicine

authors： Lee WA,Kolla S,Schreiner RJ Jr,Hirschl RB,Bartlett RH

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:Myofibroblasts express alpha-smooth muscle actin (alphaSMA), are important in tissue repair, and are present in the early phase of acute lung injury/acute respiratory distress syndrome (ALI/ARDS). We wished to determine whether bronchoalveolar lavage fluid (BALF) from ALI/ARDS patients can induce myofibroblas...

journal_title：Critical care medicine

authors： Synenki L,Chandel NS,Budinger GR,Donnelly HK,Topin J,Eisenbart J,Jovanovic B,Jain M

更新日期：2007-03-01 00:00:00

abstract：:Ischemia of the intestines damages the permeability of the intestinal wall, allowing lipopolysaccharide (LPS) (endotoxin) to leak from the gut lumen into the blood circulation, causing shock and death. We measured LPS levels associated with corticosteroid treatment vs. no treatment in cats whose superior mesenteric ar...

journal_title：Critical care medicine

authors： Gaffin SL,Gathiram P,Wells MT,Brock-Utne JG

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVES:a) To investigate whether the patient work of breathing needed to trigger inspiration is affected by the type of ventilator delivering pressure-support ventilation for mechanically ventilated pediatric patients. b) To determine whether changes in oxygen consumption (VO2) trend with changes in work of breathi...

journal_title：Critical care medicine

authors： el-Khatib MF,Chatburn RL,Potts DL,Blumer JL,Smith PG

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Glycemic control is increasingly being recognized as a priority in the treatment of critically ill patients. Titration and monitoring of insulin infusions involve frequent blood glucose measurement to achieve target glucose ranges and prevent adverse events related to hypoglycemia. Therefore, it is imperativ...

journal_title：Critical care medicine

authors： Kanji S,Buffie J,Hutton B,Bunting PS,Singh A,McDonald K,Fergusson D,McIntyre LA,Hebert PC

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:Exposure of neutrophils to low doses of bacterial lipopolysaccharides enhances their readiness to respond with inflammatory mediator generation including oxygen radical formation to a subsequently applied inflammatory stimulus ("priming"). In the present study, we investigated the role of lipid mediator synth...

journal_title：Critical care medicine

authors： Sibelius U,Hattar K,Hoffmann S,Mayer K,Grandel U,Schenkel A,Seeger W,Grimminger F

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To derive a target range of optimal sedation for the COMFORT Scale and to prospectively test that target range against intensivist assessment of adequacy of sedation. DESIGN:Serial prospective agreement cohort studies. SETTING:Twelve-bed pediatric intensive care unit in an urban academic teaching hospital. ...

journal_title：Critical care medicine

authors： Marx CM,Smith PG,Lowrie LH,Hamlett KW,Ambuel B,Yamashita TS,Blumer JL

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To compare four different methods of endotracheal lidocaine administration with respect to the site of administration. DESIGN:Randomized controlled trial. SETTING:University hospital. PATIENTS:Thirty-two female patients (43.6 +/- 11.5 years old) undergoing elective gynecologic operations with an anesthesio...

journal_title：Critical care medicine

authors： Prengel AW,Lindner KH,Hähnel J,Ahnefeld FW

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVE:To determine the specific effect of peak volume history pressure on the inflation limb of the pressure-volume curve and peak pressure-volume curve pressure on the deflation limb of the pressure-volume curve. DESIGN:Prospective assessment of pressure-volume curves in saline, lung lavage injured sheep. SETTIN...

journal_title：Critical care medicine

authors： Nishida T,Suchodolski K,Schettino GP,Sedeek K,Takeuch M,Kacmarek RM

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Recent studies have demonstrated the therapeutic effectiveness and pharmacologic mechanisms of hyperbaric oxygen therapy (HBOT) in the treatment of a systemic shock state. To elucidate the in vivo role of HBOT during sepsis, we evaluated the effects of HBOT on intestinal mucosal injury and bacterial transloca...

journal_title：Critical care medicine

authors： Sakoda M,Ueno S,Kihara K,Arikawa K,Dogomori H,Nuruki K,Takao S,Aikou T

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:The acute respiratory distress syndrome may complicate postpartum hemorrhagic shock and resuscitation, but its mechanisms are not yet well defined. We studied the lung inflammatory response to postpartum hemorrhagic shock and resuscitation in a rabbit model and the role of the nuclear factor-κB pathway. DESI...

journal_title：Critical care medicine

authors： Sheng C,Yu YH,Zhao KS,Huang LP,Lodato RF,Wang ZJ,Wang CH,Wang SH,Zha DS

更新日期：2012-05-01 00:00:00

abstract：:Trauma is the leading cause of both morbidity and mortality in the pediatric population, and traumatic injury causes > 50% of all childhood deaths. Significant mortality rates have been reported for children with traumatic brain injury. Although children have better survival rates as compared with adults with traumati...

journal_title：Critical care medicine

authors： Mazzola CA,Adelson PD

更新日期：2002-11-01 00:00:00

abstract：:The authors evaluated the effectiveness of 6% hydroxyethyl starch (hetastarch) solution for treatment of hypovolemia in 46 critically ill patients. Thirty-two of the patients were studied retrospectively and in 14 patients, cardiopulmonary variables were prospectively measured. A total of 29 patients were in shock sec...

journal_title：Critical care medicine

authors： Puri VK,Paidipaty B,White L

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVES:A cuffed tracheostomy tube facilitates prolonged mechanical ventilation and weaning but usually leads to prolonged voicelessness, which can be one of the most negative experiences of hospitalization. No randomized trials have examined the effects of targeted early communication intervention for the restorati...

journal_title：Critical care medicine

authors： Freeman-Sanderson AL,Togher L,Elkins MR,Phipps PR

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Because anemia of inflammation is common in ICU patients and hepcidin is the key regulator of iron homeostasis, we examined time-dependent changes in hepcidin, erythropoietin, iron, and inflammatory markers in surgical ICU patients with anemia. DESIGN:Prospective single-center clinical noninterventional stud...

journal_title：Critical care medicine

authors： Cherry-Bukowiec JR,Engoren M,Wiktor A,Raghavendran K,Napolitano LM

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To determine the influence of a selective, sterile central nervous system surgery on immune reactivity, particularly whether a decrease of monocytic human leukocyte antigen-DR expression, indicating immunodepression, occurs after neurosurgery and if this measurement is useful for identification of patients wi...

journal_title：Critical care medicine

authors： Asadullah K,Woiciechowsky C,Döcke WD,Liebenthal C,Wauer H,Kox W,Volk HD,Vogel S,Von Baehr R

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Despite concern over the appropriateness and quality of care provided in an intensive care unit (ICU) at the end of life, the number of Americans who receive ICU care at the end of life is unknown. We sought to describe the use of ICU care at the end of life in the United States using hospital discharge data ...

journal_title：Critical care medicine

authors： Angus DC,Barnato AE,Linde-Zwirble WT,Weissfeld LA,Watson RS,Rickert T,Rubenfeld GD,Robert Wood Johnson Foundation ICU End-Of-Life Peer Group.

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:The elevation of the percentage of regulatory CD4+CD25+ T lymphocytes (Treg) has been recently described during septic shock. The objective of the present study was to investigate whether this increased percentage was due to Treg proliferation. DESIGN:Observational study. SETTING:Adult intensive care units ...

journal_title：Critical care medicine

authors： Venet F,Pachot A,Debard AL,Bohé J,Bienvenu J,Lepape A,Monneret G

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:The role of systemic corticosteroids in pathophysiology and treatment of acute respiratory distress syndrome is controversial. Use of prehospital systemic corticosteroid therapy may prevent the development of acute respiratory distress syndrome and improve hospital outcomes. DESIGN:This is a preplanned retro...

journal_title：Critical care medicine

authors： Karnatovskaia LV,Lee AS,Gajic O,Festic E,U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS).

更新日期：2013-07-01 00:00:00