The endothelium in sepsis: source of and a target for inflammation.

abstract：OBJECTIVES:To determine the frequency of advance directives or directives disclosed by healthcare agents and their influence on decisions to withdraw/withhold life-sustaining care in neurocritically ill adults. DATA SOURCES:PubMed, Embase, and Cochrane databases. STUDY SELECTION:Screening was performed using predefin...

journal_title：Critical care medicine

authors： Sutter R,Meyer-Zehnder B,Baumann SM,Marsch S,Pargger H

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:When treating patients with cardiac arrest with mild therapeutic hypothermia, a reliable and easy-to-use temperature probe is desirable. This study was conducted to investigate the accuracy and safety of tracheal temperature as a measurement of body temperature. DESIGN:Observational cohort study. SETTING:Em...

journal_title：Critical care medicine

authors： Haugk M,Stratil P,Sterz F,Krizanac D,Testori C,Uray T,Koller J,Behringer W,Holzer M,Herkner H

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:We reviewed randomized trials of adult ICU patients of interventions hypothesized to reduce delirium burden to determine whether interventions that are more effective at reducing delirium duration are associated with a reduction in short-term mortality. DATA SOURCES:We searched CINHAHL, EMBASE, MEDLINE, and...

journal_title：Critical care medicine

authors： Al-Qadheeb NS,Balk EM,Fraser GL,Skrobik Y,Riker RR,Kress JP,Whitehead S,Devlin JW

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:To synthesize the literature describing interventions to improve hand hygiene in ICUs, to evaluate the quality of the extant research, and to outline the type, and efficacy, of interventions described. DATA SOURCES:Systematic searches were conducted in November 2016 using five electronic databases: Medline,...

journal_title：Critical care medicine

authors： Lydon S,Power M,McSharry J,Byrne M,Madden C,Squires JE,O'Connor P

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:To compare in the same patient with septic shock, respective effects of epinephrine, norepinephrine, and the combination of norepinephrine and dobutamine (5 microg/kg/min) on systemic hemodynamic parameters and gastric mucosal perfusion using gastric tonometry and laser-Doppler flowmetry techniques. DESIGN:...

journal_title：Critical care medicine

authors： Duranteau J,Sitbon P,Teboul JL,Vicaut E,Anguel N,Richard C,Samii K

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:Within minutes of reperfusing ischemic cardiomyocytes, oxidant stress dramatically increases and is associated with postresuscitation injury. Because mitochondria produce deleterious oxidants and useful metabolic substrates, utilization of electron transport chain inhibitors against reperfusion injury, though...

journal_title：Critical care medicine

authors： Anderson TC,Li CQ,Shao ZH,Hoang T,Chan KC,Hamann KJ,Becker LB,Vanden Hoek TL

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:The role of systemic corticosteroids in pathophysiology and treatment of acute respiratory distress syndrome is controversial. Use of prehospital systemic corticosteroid therapy may prevent the development of acute respiratory distress syndrome and improve hospital outcomes. DESIGN:This is a preplanned retro...

journal_title：Critical care medicine

authors： Karnatovskaia LV,Lee AS,Gajic O,Festic E,U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS).

更新日期：2013-07-01 00:00:00

abstract：:Previous studies have confirmed the improved tolerance of a peptide enteral compared to standard enteral alimentation in hypoalbuminemic, critically ill patients. Animal studies, including hypoproteinemic, volume-expanded rats, demonstrated that the protein hydrolysate of a peptide enteral formula was responsible for ...

journal_title：Critical care medicine

authors： Brinson RR,Pitts VL,Taylor AE

更新日期：1989-07-01 00:00:00

abstract：:Pulmonary artery wedge pressure (PAWP) will only reflect left atrial pressure (LAP) if continuity of fluid exists from the catheter tip to the left atrium. Either increased airway pressure or decreased hydrostatic pressure may lead to discontinuity of the fluid column and midinterpretation of PAWP. Simultaneous measur...

journal_title：Critical care medicine

authors： Kane PB,Askanazi J,Neville JF Jr,Mon RL,Hanson EL,Webb WR

更新日期：1978-01-01 00:00:00

abstract：:The heart rate variability (HRV) of 82 patients exhibiting sinus rhythm and admitted for possible myocardial infarction (MI) was evaluated. Using a simple information entropy measure to quantify the HRV, patients subsequently diagnosed with MI or experiencing significant dysrhythmia (n = 35) exhibited less entropy (0....

journal_title：Critical care medicine

authors： Zbilut JP,Lawson L

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To document the effects of propofol on the hemodynamic and inflammatory responses to endotoxemia in an animal model. DESIGN:Randomized, prospective laboratory study. SETTING:University experimental laboratory. SUBJECTS:Thirty-two male rats. INTERVENTIONS:The animals were randomly assigned to one of four g...

journal_title：Critical care medicine

authors： Taniguchi T,Yamamoto K,Ohmoto N,Ohta K,Kobayashi T

更新日期：2000-04-01 00:00:00

abstract：:The disadvantages of external ventricular drainage are the threat of sepsis and the nuisance of dislodging a precarious system in routine care. The experience of the authors with nearly 200 cases using a long ventricular catheter demonstrates that a subgaleal tunnel can be easily made for the ventricular catheter usin...

journal_title：Critical care medicine

authors： Saunders RL,Lyons TA

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:To describe critical illnesses that occur commonly in patients with human immunodeficiency virus (HIV) infection. METHODS:We reviewed and summarized the literature on critical illness in HIV infection using a computerized MEDLINE search. SUMMARY:In the last 10 yrs, our perception of HIV infection and acquir...

journal_title：Critical care medicine

authors： Rosen MJ,Narasimhan M

更新日期：2006-09-01 00:00:00

abstract：:Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 +/- 2.7 micrograms/kg . min) increased both cardiac index (from 1.7 +/- 0.4 to 2.3 +/- 0.6 L/min . m2, p less t...

journal_title：Critical care medicine

authors： Jardin F,Genevray B,Brun-Ney D,Margairaz A

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To determine the effect of two doses of prostaglandin E1 (PGE1, alprostadil) combined with unfractionated heparin on the hemofilter life-span and the coagulation profile during continuous venovenous hemofiltration. DESIGN:Prospective, randomized, controlled trial. SETTING:Intensive care unit at a university...

journal_title：Critical care medicine

authors： Kozek-Langenecker SA,Kettner SC,Oismueller C,Gonano C,Speiser W,Zimpfer M

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVES:Augmented renal clearance might lead to subtherapeutic plasma levels of drugs with predominant renal clearance. Early identification of augmented renal clearance remains challenging for the ICU physician. We developed and validated our augmented renal clearance predictor, a clinical prediction model for augm...

journal_title：Critical care medicine

authors： Gijsen M,Huang CY,Flechet M,Van Daele R,Declercq P,Debaveye Y,Meersseman P,Meyfroidt G,Wauters J,Spriet I

更新日期：2020-12-01 00:00:00

abstract：:Comparative hemodynamic measurements recorded in 19 cases of septic shock associated with Neisseria meningitidis bacteremia and in 20 shock cases associated with bacteremia due to other Gram-negative bacilli showed a significantly higher incidence of early myocardial depression in the cases with meningococcal infectio...

journal_title：Critical care medicine

authors： Monsalve F,Rucabado L,Salvador A,Bonastre J,Cuñat J,Ruano M

更新日期：1984-12-01 00:00:00

abstract：:The resolution time of pneumothorax in neonates requiring tube thoracotomy is not known. We found that 28%, 50%, and 83% of 54 pneumothoraces in 40 neonates resolved within 24, 96, and 168 h of tube thoracotomy, respectively. Pneumothoraces that persisted beyond 168 h were in infants requiring ventilatory assistance. ...

journal_title：Critical care medicine

authors： Bhatia J,Mathew OP

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVES:To test the hypothesis that after cecal ligation and puncture in the rat, there is increased expression of the tumor necrosis factor (TNF)/interleukin-1-dependent, acute-phase reactant alpha 1-acid glycoprotein in the liver, and that this change correlates temporally with increased abundance of TNF-alpha in ...

journal_title：Critical care medicine

authors： Andrejko KM,Deutschman CS

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:Neurologic damage following cardiac arrest remains a major burden for modern resuscitation medicine. Cardiopulmonary resuscitation with extracorporeal circulatory support holds the potential to reduce morbidity and mortality. Furthermore, the endogenous gasotransmitter carbon monoxide attracts attention in r...

journal_title：Critical care medicine

authors： Wollborn J,Steiger C,Doostkam S,Schallner N,Schroeter N,Kari FA,Meinel L,Buerkle H,Schick MA,Goebel U

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the comparative efficacy of enteral cisapride, metoclopramide, erythromycin, and placebo for promoting gastric emptying in critically ill patients with intolerance to gastric enteral nutrition (EN). DESIGN:A randomized, crossover study. SETTING:Adult medical intensive care unit at a university-a...

journal_title：Critical care medicine

authors： MacLaren R,Kuhl DA,Gervasio JM,Brown RO,Dickerson RN,Livingston TN,Swift K,Headley S,Kudsk KA,Lima JJ

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVES:Increasing time to mechanical ventilation and high-flow nasal cannula use may be associated with mortality in coronavirus disease 2019. We examined the impact of time to intubation and use of high-flow nasal cannula on clinical outcomes in patients with coronavirus disease 2019. DESIGN:Retrospective cohort ...

journal_title：Critical care medicine

authors： Hernandez-Romieu AC,Adelman MW,Hockstein MA,Robichaux CJ,Edwards JA,Fazio JC,Blum JM,Jabaley CS,Caridi-Scheible M,Martin GS,Murphy DJ,Auld SC,Emory COVID-19 Quality and Clinical Research Collaborative.

更新日期：2020-11-01 00:00:00

abstract：:Bradycardia is common in critical care units. It may be transient, asymptomatic and of little consequence, or life-threatening. Bradycardia may result from abnormalities of the sinus node, atrioventricular node, or the His-Purkinje system. It may also be precipitated by drug effects or enhanced vagal tone. Proper diag...

journal_title：Critical care medicine

authors： Kaushik V,Leon AR,Forrester JS Jr,Trohman RG

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Acute renal failure remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key components in the development of acute renal failure. Although the Duffy antigen receptor for chemokines (DARC) is present in several tissues and a highly specific ligand for vari...

journal_title：Critical care medicine

authors： Zarbock A,Schmolke M,Bockhorn SG,Scharte M,Buschmann K,Ley K,Singbartl K

更新日期：2007-09-01 00:00:00

abstract：:Percutaneous cholecystostomy was employed successfully as an alternative to cholecystectomy for the treatment of acute cholecystitis with perforation in an elderly woman. The procedure, performed portably in the cardiac care unit, was selected because progressive cardiac and renal decompensation made the patient an ex...

journal_title：Critical care medicine

authors： Longmaid HE 3rd,Bassett JG,Gottlieb H

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVES:Conflict is common between physicians and surrogate decision makers around end-of-life care in ICU. Involving experts in conflict management improve outcomes, but little is known about what differences in conflict management styles may explain the benefit. We used simulation to examine potential differences ...

journal_title：Critical care medicine

authors： Chiarchiaro J,White DB,Ernecoff NC,Buddadhumaruk P,Schuster RA,Arnold RM

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Millions of patients are discharged from intensive care units annually. These intensive care survivors and their families frequently report a wide range of impairments in their health status which may last for months and years after hospital discharge. OBJECTIVES:To report on a 2-day Society of Critical Car...

journal_title：Critical care medicine

authors： Needham DM,Davidson J,Cohen H,Hopkins RO,Weinert C,Wunsch H,Zawistowski C,Bemis-Dougherty A,Berney SC,Bienvenu OJ,Brady SL,Brodsky MB,Denehy L,Elliott D,Flatley C,Harabin AL,Jones C,Louis D,Meltzer W,Muldoon SR,Pa

更新日期：2012-02-01 00:00:00

abstract：:Position of the CVP port on a flow-directed balloon-tip pulmonary arterial catheter affects the accuracy of both thermodilution cardiac output determinations and CVP measurements. Systemic allometry (the study of the growth of a part in relation to the total organism) has been used to determine an easily measured inde...

journal_title：Critical care medicine

authors： Borland LM

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:To review the anti-inflammatory and anti-apoptotic properties of drotrecogin alfa (activated) (recombinant human activated protein C), emphasizing its modulatory effects on endothelial nuclear factor-kappaB. We propose a broad anti-inflammatory effect of drotrecogin alfa (activated), acting on both endotheliu...

journal_title：Critical care medicine

authors： Joyce DE,Grinnell BW

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Noncuffed, percutaneously inserted central venous catheters (CVCs) are widely used and cause at least 250,000 bloodstream infections (BSIs) in U.S. hospitals each year. We report a prospective study to determine whether inflammation at the insertion site is predictive of CVC-related BSI. METHODS:Percutaneou...

journal_title：Critical care medicine

authors： Safdar N,Maki DG

更新日期：2002-12-01 00:00:00