Temporal lobe epilepsy subtypes: differential patterns of cerebral perfusion on ictal SPECT.

abstract：PURPOSE:Epileptic spasms are seizures that occur predominantly in children and are characterized by clusters of brief axial movements. Epileptic spasms may occur in the context of a variety of syndromes. Previous research has found that epileptic spasms occur in a sleep/wake and diurnal rhythm. The purpose of this stud...

journal_title：Epilepsia

authors： Ramgopal S,Shah A,Zarowski M,Vendrame M,Gregas M,Alexopoulos AV,Loddenkemper T,Kothare SV

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:Deep brain stimulation has been used by several investigators to prevent the occurrence of spontaneous seizures in patients with intractable epilepsy. With the kainic acid rat model of spontaneous recurrent seizures, we examined the consequences of subthreshold electrical stimulation of commissural pathways and...

journal_title：Epilepsia

authors： Bragin A,Wilson CL,Engel J Jr

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to systematically review the literature on the interictal language profile in adult patients with epilepsy. METHODS:An extensive literature search was performed using MEDLINE, Embase, PsycINFO, Cochrane Central Register of Controlled Trials, PASCAL, and PSYNDEXplus databases. Ke...

journal_title：Epilepsia

authors： Bartha-Doering L,Trinka E

更新日期：2014-10-01 00:00:00

abstract：:Over the past decade, much progress has been made in understanding the mechanisms of ketogenic diet (KD) action. From the complex systemic and metabolic changes induced by the KD have emerged innovative hypotheses attempting to link biochemical adaptations to its clinical effects. Despite such developments, the fundam...

journal_title：Epilepsia

authors： Rho JM,Sankar R

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:We studied heart-rate (HR) changes at the transition from the preictal to the ictal state in patients with focal epilepsies to gain some insight into the mechanisms involved in the neuronal regulation of cardiovascular function. METHODS:We assessed ECG changes during 145 seizures recorded with scalp EEG in 58 ...

journal_title：Epilepsia

authors： Leutmezer F,Schernthaner C,Lurger S,Pötzelberger K,Baumgartner C

更新日期：2003-03-01 00:00:00

abstract：:The relationship between dreams and epilepsy is illustrated by two patients whose awake epileptic seizures and recurrent dreams during night sleep had similar content. In both of our cases the EEG showed right anterior temporal spike discharge, suggesting a role for the temporal lobe in the association between dreams ...

journal_title：Epilepsia

authors： Reami DO,Silva DF,Albuquerque M,Campos CJ

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:Ictal asystole (IA) and ictal bradycardia (IB) are rare autonomic symptoms during epileptic seizures and may be potentially life-threatening. Guidelines for the care of these patients are missing. The aim of this multicenter study was to evaluate the management and long-term outcome in patients with IA and IB. ...

journal_title：Epilepsia

authors： Strzelczyk A,Cenusa M,Bauer S,Hamer HM,Mothersill IW,Grunwald T,Hillenbrand B,Ebner A,Steinhoff BJ,Krämer G,Rosenow F

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Previous studies have established the importance of the insular cortex and temporal lobe in cardiovascular autonomic modulation. Some investigators, based on the results of cortical stimulation response, functional imaging, EEG recordings of seizures, and lesional studies, have suggested that cardiac sympatheti...

journal_title：Epilepsia

authors： Britton JW,Ghearing GR,Benarroch EE,Cascino GD

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:High-dose i.v. opioids (e.g., alfentanil, 50 microg/kg bolus) are known to increase the intraoperative reading of epileptiform activity during epilepsy surgery (ES), thereby facilitating localization of the epileptogenic zone (i.e., the site of ictal onset and initial seizure propagation). However, this phenome...

journal_title：Epilepsia

authors： Wass CT,Grady RE,Fessler AJ,Cascino GD,Lozada L,Bechtle PS,Marsh WR,Sharbrough FW,Schroeder DR

更新日期：2001-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize the incidence and etiology of temporal lobe epilepsy (TLE) in a community-based cohort of children with new-onset disease. METHODS:A community-based cohort of 30 children with TLE was studied. The patients had new-onset disease before age 14 years between 1995 and 1999...

journal_title：Epilepsia

authors： Sztriha L,Gururaj AK,Bener A,Nork M

更新日期：2002-01-01 00:00:00

abstract：:In order to evaluate immediate recall and learning in epileptic patients, four tests were chosen: Wechsler's memory span for digits, graphic reproduction of geometric figures from the Wechsler Memory Scale, learning of a list of words from the Rey Memory Scale, and recognition of these words. These tests were performe...

journal_title：Epilepsia

authors： Loiseau P,Strube E,Broustet D,Battellochi S,Gomeni C,Morselli PL

更新日期：1983-04-01 00:00:00

abstract：PURPOSE:To describe the semiologic features of aggressive behaviors observed in human epileptic seizures with particular reference to the act of biting a conspecific. METHODS:We analyzed the biting behavior (BB) and other aggressive gestures occurring in a group of 11 patients retrospectively selected from >1,000 pati...

journal_title：Epilepsia

authors： Tassinari CA,Tassi L,Calandra-Buonaura G,Stanzani-Maserati M,Fini N,Pizza F,Sartori I,Michelucci R,Lo Russo G,Meletti S

更新日期：2005-05-01 00:00:00

abstract：:The tendency for four strains of parathyroidectomized (PTx) rats to convulse after pinealectomy (Px) was observed in this experiment; telencephalic serotonin, norepinephrine, and dopamine were examined to note any correlation between amines and convulsions. The strains of rats tested were Sprague-Dawley, Wistar, Long-...

journal_title：Epilepsia

authors： Philo R,Reiter RJ

更新日期：1978-04-01 00:00:00

abstract：PURPOSE:Brivaracetam (BRV) is a new anticonvulsant under development. Although BRV is an analog of levetiracetam (LEV), in addition to being an SV2A ligand, it also inhibits sodium channels in a voltage-dependent manner. The cognitive effects of BRV are uncertain. METHODS:A randomized, double-blind, placebo-controlled...

journal_title：Epilepsia

authors： Meador KJ,Gevins A,Leese PT,Otoul C,Loring DW

更新日期：2011-02-01 00:00:00

abstract：:Despite the introduction of newer antiepileptic drugs (AEDs), nonresponsiveness to AEDs remains a common problem in epilepsy clinics. There may be important genetic determinants for responsiveness, and this discussion focused on some potential areas: drug transporters; drug-metabolizing enzymes, and ion channels. We r...

journal_title：Epilepsia

authors： Ramachandran V,Shorvon SD

更新日期：2003-01-01 00:00:00

abstract：:We examined the clinical significance of bisynchronous spike-wave complexes which appear in EEGs of some patients with focal spikes in one or both temporal lobes. Few features distinguished patients with bisynchronous spike-waves from those with only focal temporal spikes: a higher incidence of patients with more than...

journal_title：Epilepsia

authors： Sadler RM,Blume WT

更新日期：1989-03-01 00:00:00

abstract：:We studied 36 drop seizures in 5 patients with myoclonic astatic epilepsy of early childhood (MAEE) with simultaneous split-screen video recording and polygraph. Sixteen were falling attacks and 20 were either less severe attacks exhibiting only deep head nodding or seizures equivalent to drop attacks in terms of icta...

journal_title：Epilepsia

authors： Oguni H,Fukuyama Y,Imaizumi Y,Uehara T

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:Pathogenic variants of KCNQ2, which encode a potassium channel subunit, cause either benign (familial) neonatal epilepsy-B(F)NE)-or KCNQ2 encephalopathy (KCNQ2 DEE). We examined the characteristics of KCNQ2 variants. METHODS:KCNQ2 pathogenic variants were collected from in-house data and two large disease da...

journal_title：Epilepsia

authors： Goto A,Ishii A,Shibata M,Ihara Y,Cooper EC,Hirose S

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:In patients with mesial temporal lobe epilepsy (MTLE) it remains an unresolved issue whether the interictal decrease in N-acetyl aspartate (NAA) detected by proton magnetic resonance spectroscopy ((1)H-MRS) reflects the epilepsy-associated loss of hippocampal pyramidal neurons or metabolic dysfunction. METHODS...

journal_title：Epilepsia

authors： Vielhaber S,Niessen HG,Debska-Vielhaber G,Kudin AP,Wellmer J,Kaufmann J,Schönfeld MA,Fendrich R,Willker W,Leibfritz D,Schramm J,Elger CE,Heinze HJ,Kunz WS

更新日期：2008-01-01 00:00:00

abstract：:The course and outcome of epilepsy following central nervous system (CNS) infections has been poorly characterized. Likewise, the impact of antimicrobial treatment as well as other preventative and therapeutic interventions on the development of epilepsy following neurological infectious disorders has been insufficien...

journal_title：Epilepsia

authors： Singh G,Prabhakar S

更新日期：2008-08-01 00:00:00

abstract：:Male and female sexuality and reproductive functions are complex systems with cortical, limbic system, hypothalamic, pituitary, and end organ interactions. Sexual steroids are produced in the sexual glands, the adrenals, and the brain. They undergo interconversion in the brain, bind to different brain areas, and have ...

journal_title：Epilepsia

authors： Penovich PE

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:Generalized convulsive status epilepticus (GCSE) needs immediate management. Despite guidelines, adherence to management protocols is often poor, this contributing to poor outcome. We aimed to evaluate the usefulness of a management protocol in GCSE. METHODS:This is a prospective population-based study of cons...

journal_title：Epilepsia

authors： Aranda A,Foucart G,Ducassé JL,Grolleau S,McGonigal A,Valton L

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Identifying adverse outcomes and examining trends and causes of nonelective admissions among persons with epilepsy would be beneficial to optimize patient care and reduce health services utilization. We examined the association of epilepsy with discharge status, in-hospital mortality, length-of-stay, and char...

journal_title：Epilepsia

authors： Kwon CS,Wong B,Agarwal P,Lin JY,Mazumdar M,Dhamoon M,Jetté N

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To describe the long-term outcome of childhood-onset secondarily generalized epilepsies (SGEs). METHODS:Children were identified from the Nova Scotia population-based epilepsy study (n=692). Onset of epilepsy was between 1977 and 1985, and follow-up was mainly in 2003. SGE was defined as having a mixture of mo...

journal_title：Epilepsia

authors： Camfield P,Camfield C

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:Vigabatrin (VGB) and lamotrigine (LTG) are two new antiepileptic drugs (AEDs) with different mechanisms of action for treatment of refractory epilepsies. Previous reports have indicated efficacy of both drugs in a number of epileptic syndromes. METHODS:We compared these new AEDs drugs to determine their respec...

journal_title：Epilepsia

authors： Bélanger S,Coulombe G,Carmant L

更新日期：1998-08-01 00:00:00

abstract：:The incidence of biochemical signs of vitamin D deficiency and the effects of vitamin D supplementation were investigated in 83 children and 95 adults on chronic antiepileptic therapy and 40 mentally retarded controls living under comparable conditions. Low 25-hydroxyvitamin D and serum calcium, and elevated immunorea...

journal_title：Epilepsia

authors： Offermann G,Pinto V,Kruse R

更新日期：1979-02-01 00:00:00

abstract：:We report the case of a 3-year-old boy with status gelasticus symptomatic to a giant hypothalamic hamartoma despite two previous hypothalamic hamartoma surgeries using pterional approaches from each side. Following his third resection employing an endoscopic, transventricular approach, he has been seizure free for 6 m...

journal_title：Epilepsia

authors： Ng YT,Rekate HL

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Movement-based wearable sensors are used for detection of convulsive seizures. The identification of the absence of motion following a seizure, known as post-ictal immobility (PI), may represent a potential additional application of wearables. PI has been associated with potentially life-threatening complicat...

journal_title：Epilepsia

authors： Bruno E,Böttcher S,Biondi A,Epitashvili N,Manyakov NV,Lees S,Schulze-Bonhage A,Richardson MP,RADAR-CNS Consortium.

更新日期：2020-07-01 00:00:00

abstract：:A variety of experimental paradigms have been utilized to study verbal learning and memory ability in patients with epilepsy. One commonly used paradigm, the free recall of a list(s) of related or unrelated words, has revealed a variety of performance anomalies in patients with complex partial seizures (CPS) of tempor...

journal_title：Epilepsia

authors： Hermann BP,Wyler AR,Richey ET,Rea JM

更新日期：1987-09-01 00:00:00

abstract：:Periventricular nodular heterotopia (PNH) is a common structural malformation of cortical development. Mutations in the filamin A gene are frequent in familial cases with X-linked PNH. However, many cases with sporadic PNH remain genetically unexplained. Although medically refractory epilepsy often brings attention to...

journal_title：Epilepsia

authors： Montier L,Haneef Z,Gavvala J,Yoshor D,North R,Verla T,Van Ness PC,Drabek J,Goldman AM

更新日期：2019-10-01 00:00:00