Pharmacokinetics of pyropheophorbide-a-hexyl ether in the dog.

abstract：OBJECTIVE:To determine whether laser light can improve healing of skin wounds by killing wound bacteria while simultaneously accelerating host tissue activity. MATERIALS AND METHODS:Wounds on the rat dorsum were irradiated or sham-irradiated three times weekly from days 1 to 19 using 635 or 808 nm diode lasers at 1 or...

journal_title：Lasers in surgery and medicine

authors： Nussbaum EL,Mazzulli T,Pritzker KP,Heras FL,Jing F,Lilge L

更新日期：2009-07-01 00:00:00

abstract：:Hyperthermia induced by a microwave source (2,450 MHz) was used alone and in combination with photodynamic therapy (PDT) to treat the SMT-F, EMT-6, and RIF animal tumors in vivo. PDT was administered using either Photofrin I or II as the photosensitizer and an argon-pumped tunable dye laser (630 nm) as the light sourc...

journal_title：Lasers in surgery and medicine

authors： Waldow SM,Henderson BW,Dougherty TJ

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Biofilm-related diseases such as caries and periodontal disease are prevalent chronic oral infections which pose significant oral and general health risks. Biofilms are sessile communities attached to surfaces. Photodynamic therapy (PDT) has been demonstrated to have a significant anti-microbi...

journal_title：Lasers in surgery and medicine

authors： Mang TS,Tayal DP,Baier R

更新日期：2012-09-01 00:00:00

abstract：:We report the first study of the application of excimer lasers in dentistry for the treatment of dental root canals. High-energy ultraviolet (UV) radiation emitted by an XeCl excimer laser (308 nm) and delivered through suitable optical fibers can be used to remove residual organic tissue from the canals. To this aim,...

journal_title：Lasers in surgery and medicine

authors： Pini R,Salimbeni R,Vannini M,Barone R,Clauser C

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The reactive oxygen mechanisms associated with cell damage after photodynamic therapy (PDT) may be exploited to enhance tumor destruction. Pharmacological reduction of glutathione (GSH), an inhibitor of reactive oxygen species, can be induced by administration of buthionine sulfoximine (BSO). ...

journal_title：Lasers in surgery and medicine

authors： Jiang F,Lilge L,Belcuig M,Singh G,Grenier J,Li Y,Chopp M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To functionally evaluate the efficacy of glatiramer acetate (Cop-1) as a neuroprotective treatment for laser-induced retinal injuries in rats. STUDY DESIGN/MATERIALS AND METHODS:Using standard lasering and flash ERG techniques, we evaluated the effect of photocoagulation and of Cop-1 treatmen...

journal_title：Lasers in surgery and medicine

authors： Belokopytov M,Ben-Shlomo G,Rosner M,Belkin M,Dubinski G,Epstein Y,Ofri R

更新日期：2008-03-01 00:00:00

abstract：:The acute or emergency treatment of traumatic tattoos has been based on the principles of immediate and thorough removal of all particles. The delayed treatment of traumatic tattoos has classically been with overgrafting or dermabrasion. We developed an animal model for traumatic tattoos. Two levels of wounds were mad...

journal_title：Lasers in surgery and medicine

authors： Sunde D,Apfelberg DB,Sergott T

更新日期：1990-01-01 00:00:00

abstract：:The distribution of light in laser-irradiated biological medium is computed using four different procedures. Values computed with Beer's law of attenuation, Kubelka-Munk theory, the diffusion approximation, and a seven-flux model are compared. The proper conditions for using each model are discussed. ...

journal_title：Lasers in surgery and medicine

authors： Welch AJ,Yoon G,van Gemert MJ

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Laser ablation of stratum corneum (SC) enhances transdermal delivery of hydrophilic drugs. The influence of the infrared (IR) (lambda = 1,064 nm), visible (lambda = 532 nm), and ultraviolet (UV) (lambda = 355 nm) radiations of a Nd:YAG laser on transdermal delivery of 5-Fluorouracil (5-Fu) acro...

journal_title：Lasers in surgery and medicine

authors： Gómez C,Costela A,García-Moreno I,Llanes F,Teijón JM,Blanco D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In order to improve selectivity of photodynamic therapy (PDT) to choroidal neovascularization (CNV) associated with age-related macular degeneration, a laser scanning technique was applied to perform focal laser irradiation to the retina, and the occlusion effects of a new device to the chorio...

journal_title：Lasers in surgery and medicine

authors： Obana A,Gohto Y

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Oral mucositis is a dose-limiting and painful side effect of radiotherapy (RT) and/or chemotherapy in cancer patients. The purpose of the present study was to analyze the effect of different protocols of laser phototherapy (LPT) on the grade of mucositis and degree of pain in patients under RT....

journal_title：Lasers in surgery and medicine

authors： Simões A,Eduardo FP,Luiz AC,Campos L,Sá PH,Cristófaro M,Marques MM,Eduardo CP

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In recent years, clinical low-intensity laser therapy practice has used pulsed radiation, mainly from semiconductor lasers. Experimental works devoted to the study of relationships between biological and clinical effects and parameters of pulsed radiation are practically absent. STUDY DESIGN/M...

journal_title：Lasers in surgery and medicine

authors： Karu TI,Pyatibrat LV,Ryabykh TP

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:An ideal treatment for pilonidal disease should feature a low recurrence rate, minimal incision, and rapid return to daily activities. We compared the outcomes of the well-defined Karydakis technique (KT) and a combination of pit excision (PE) and sinus tract ablation using 1,470-nm diode lase...

journal_title：Lasers in surgery and medicine

authors： Yardimci VH

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Knowledge about optical parameters and the resultant light distribution in laser-treated tissue is important for predicting the effects of laser-induced thermotherapy of liver metastases (LITT). MATERIALS AND METHODS:The absorption and scattering coefficients as well as the anisotropy factors ...

journal_title：Lasers in surgery and medicine

authors： Germer CT,Roggan A,Ritz JP,Isbert C,Albrecht D,Müller G,Buhr HJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Q-switched lasers had been used in the treatment of lentigo maligna but their role remains controversial. While previous studies have addressed the change in adhesion molecule expression after sub-lethal laser damage, no study has addressed the impact of sub-lethal laser damage at a molecular ...

journal_title：Lasers in surgery and medicine

authors： Chan HH,Xiang L,Leung JC,Tsang KW,Lai KN

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This laboratory animal study is a comparison of Nd:YAG 1064 nm and diode 810 nm laser wavelengths in brain interstitial laser photocoagulation (ILP). Specific goals were to identify potential complications and physical characteristics of the thermal damage at both wavelengths prior to undertaki...

journal_title：Lasers in surgery and medicine

authors： Wyman DR,Schatz SW,Maguire JA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previously, we have shown that a 43°C pretreatment can provide thermotolerance to a following, more severe, thermal stress at 45°C. Using cells that lack the Hsp70 gene, we have also shown that there is still some thermotolerance in the absence of HSP70 protein. The purpose of this study was t...

journal_title：Lasers in surgery and medicine

authors： Beckham JT,Wilmink GJ,Opalenik SR,Mackanos MA,Abraham AA,Takahashi K,Contag CH,Takahashi T,Jansen ED

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The conventional pulsed-dye laser (wavelength 585 nm, pulse duration 0.5 milliseconds) is seen as the standard treatment for port wine stains (PWS). Using the pulsed-dye laser at wavelengths of 590, 595, and 600 nm and at varying pulse durations of 1.5-40 milliseconds is one of the newest deve...

journal_title：Lasers in surgery and medicine

authors： Greve B,Raulin C

更新日期：2004-01-01 00:00:00

abstract：:This study characterizes the special properties of hematoporphyrin derivative (HpD) (Photofrin I) and Photofrin II with respect to the absorption and fluorescence spectra of the subfractions of the compounds in both solution and cells. In addition, data are presented demonstrating variation in the spectral amplitudes ...

journal_title：Lasers in surgery and medicine

authors： Sun CH,Duzman E,Mellott J,Liaw LH,Berns MW

更新日期：1987-01-01 00:00:00

abstract：:Histological investigation of the dog's myocardium performed 7 and 25 days after irradiation with different doses of Nd-YAG laser show that the damage zone has the shape of a hollow sphere with minor changes in cardiomyocytes in the central part of the sphere. The small blood vessels in the irradiated zone remained un...

journal_title：Lasers in surgery and medicine

authors： Obelienius V,Knepa A,Lubite Y,Ambartzumian R,Isakov V,Koshelev E,Markin E

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The argon laser-assisted vascular anastomosis may solve the problems of conventional sutured anastomosis, such as vascular stenosis and arrest of growth owing to a foreign-body reaction to suture material. STUDY DESIGN/MATERIALS AND METHODS:Twelve argon laser-assisted vascular anastomoses, se...

journal_title：Lasers in surgery and medicine

authors： Chikamatsu E,Sakurai T,Nishikimi N,Yano T,Nimura Y

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Photodynamic therapy (PDT) may be a less invasive treatment for lung cancer. Our newly developed surface layer-preserving PDT (SPPDT) technique enables us to irradiate deep tumor while preserving the overlying tissue. The aim of this basic study was to verify that the SPPDT technique might be ...

journal_title：Lasers in surgery and medicine

authors： Kawakubo M,Eguchi K,Arai T,Kobayashi K,Hamblin MR

更新日期：2012-08-01 00:00:00

abstract：:The fourth harmonic wavelength (266 nm) of a neodymium YAG laser was used to cut precise grooves on the surface of the human cornea. Well-controlled cuts were made using the laser operating at 1.3 kHz. The width of the grooves was 2-3 micron. The depth could be controlled by varying the amount of laser exposure. ...

journal_title：Lasers in surgery and medicine

authors： Berns MW,Gaster RN

更新日期：1985-01-01 00:00:00

abstract：:Laser photocoagulation has proven to be valuable in the treatment of port-wine stains. In this application, the minimal blanching technique is used as an indicator of suitable dosage since it has been demonstrated that the immediate appearance a white mark is required to achieve permanent blanching a few months later....

journal_title：Lasers in surgery and medicine

authors： Mordon S,Beacco C,Rotteleur G,Brunetaud JM

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The use of pulsed dye laser (PDL) and fractional CO2 (FX CO2 ) laser therapy to treat and/or prevent scarring following burn injury is becoming more widespread with a number of studies reporting reduction in scar erythema and pruritus following treatment with lasers. While the majority of studi...

journal_title：Lasers in surgery and medicine

authors： Bailey JK,Blackstone BN,DeBruler DM,Kim JY,Baumann ME,McFarland KL,Imeokparia FO,Supp DM,Powell HM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Kenalog application onto surgical wounds has been used to control dynamic pain following Laser-Assisted-Uvulo-Palatoplasty (LAUP) with good results in our department. When the effect was sub-optimal, insufficient ointment over the superior-lateral corner of wounds were always noted. Fulfilling...

journal_title：Lasers in surgery and medicine

authors： Li LP,Lee SS,Chuang AY,Niddam DM,Tung TH,Chen JK

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Energy-based treatments have been found to be a promising treatment modality for improving stress urinary incontinence (SUI) symptoms. This prospective two-center study was designed to evaluate the efficacy of fractional-pixel CO2 laser for the treatment of SUI. STUDY DESIGN/MATERIALS AND MET...

journal_title：Lasers in surgery and medicine

authors： Franić D,Fistonić I,Franić-Ivanišević M,Perdija Ž,Križmarić M

更新日期：2020-09-08 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In coupling laser with micromanipulator through fiberoptics, the resulting diameter of the spot is limited by the laws of geometrical optics, because of the high numerical aperture (N.A.) of fiberoptic radiation. A new method for the reduction of spot size diameter is suggested. STUDY DESIGN/M...

journal_title：Lasers in surgery and medicine

authors： Logunov SL,Lemberg VG

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Attempts at using the pulsed dye laser (PDL) operating at 585 nm wavelength and 0.45 milliseconds pulse duration to treat leg veins have been notably unsuccessful. The aim of this study is to evaluate the efficacy and complications of the 595 nm long PDL in the treatment of leg veins. STUDY D...

journal_title：Lasers in surgery and medicine

authors： Kono T,Yamaki T,Erçöçen AR,Fujiwara O,Nozaki M

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The sanitation of the root canal system and the adjacent dentin has always been a key requirement for successful endodontics. In recent years, various laser systems have provided a major contribution to this aim, namely the Nd:YAG-, the 810 nm Diode-, the Er:YAG-, and the Er,Cr:YSGG laser. Num...

journal_title：Lasers in surgery and medicine

authors： Schoop U,Kluger W,Dervisbegovic S,Goharkhay K,Wernisch J,Georgopoulos A,Sperr W,Moritz A

更新日期：2006-07-01 00:00:00