Abstract:
BACKGROUND AND OBJECTIVES:The sanitation of the root canal system and the adjacent dentin has always been a key requirement for successful endodontics. In recent years, various laser systems have provided a major contribution to this aim, namely the Nd:YAG-, the 810 nm Diode-, the Er:YAG-, and the Er,Cr:YSGG laser. Numerous studies could prove their efficiency within the endodontic procedure. Recently, two new wavelengths have been introduced to the field of oral laser applications: The KTP laser emitting at 532 nm and the 980 nm diode laser. The present in vitro investigation was performed to evaluate the effects of these laser systems focusing on their antibacterial effect in deep layers of dentin and their impact on the root canal dentin. STUDY DESIGN/MATERIALS AND METHODS:Two-hundred slices of root dentin with a thickness of 1 mm were obtained by longitudinal cuts of freshly extracted human premolars. The samples were steam sterilized and subsequently inoculated with a suspension of either Escherichia coli or Enterococcus faecalis. After the incubation, the samples were randomly assigned to the two different laser systems tested. Each laser group consisted of two different operational settings and a control. The dentinal samples underwent "indirect" laser irradiation through the dentin from the bacteria-free side and were then subjected to a classical quantitative microbiologic evaluation. To assess the temperature increase during the irradiation procedure, additional measurements were carried out using a thermocouple. To assess the impacts on the root canal walls, 20 additional samples underwent laser irradiation at two different settings and were subjected to scanning electron microscopy. RESULTS:Microbiology indicated that both laser systems were capable of significant reductions in both test strains. At an effective output power of 1 W, E. coli was reduced by at least 3 log steps in most of the samples by the tested wavelengths, with the best results for the KTP laser showing complete eradication of E. coli in 75% of the samples. E. faecalis, a stubborn invader of the root canal, showed minor changes in bacterial count at 1 W. Using the higher setting of 1.5 W, significant reductions of E. coli were again observed with both laser systems, where the lasers were capable of complete eradication of E. faecalis to a significant extent. There was no significant relation between the temperature increase and the bactericidal effect. CONCLUSIONS:The present study demonstrates that both wavelengths investigated could be suitable for the disinfection of even the deeper layers of dentin and equal the results achieved by established wavelengths in state-of-the-art endodontics.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Schoop U,Kluger W,Dervisbegovic S,Goharkhay K,Wernisch J,Georgopoulos A,Sperr W,Moritz Adoi
10.1002/lsm.20331subject
Has Abstractpub_date
2006-07-01 00:00:00pages
624-30issue
6eissn
0196-8092issn
1096-9101journal_volume
38pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVE:The goal of this study was to use an inexpensive macroscopic imaging system to monitor tumor progression in mouse models in real-time with minimal intervention. STUDY DESIGN/MATERIALS AND METHODS:Illumination is provided via a xenon arc lamp and a fiber optic probe which delivers white light o...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20409
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Interstitial photodynamic therapy (iPDT) of non-resectable recurrent glioblastoma using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has shown a promising outcome. It remained unclear, however, to what extent inter- and intra-tumoural differences of PpIX concentrations influence...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
doi:10.1002/lsm.22126
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abstract:BACKGROUND AND OBJECTIVE:In recent years, selective photothermolysis (PT) based on broadband light and assisted by skin vacuum (Photopneumatic Technology or PPx, by Aesthera) was introduced into the aesthetic market for epilation (hair removal) procedures. The present study aims to: (a) determine the overall effect of ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20743
更新日期:2009-02-01 00:00:00
abstract:INTRODUCTION:The pulsed dye laser (PDL) using varying fluences and pulse durations have been used to treat hemangiomas. This study aims to examine the efficacy and safety of the 595-nm PDL for the treatment of infantile hemangiomas using short (1.5-3 milliseconds) versus long (10 milliseconds) pulse durations and high ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.21159
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The clinical application of laser-assisted vascular anastomosis is afflicted by unreliable and low bonding strengths as well as tedious handling during microvascular surgery. The challenge to be met arises from the flow-off of the chromophore during soldering that changes the absorption and sta...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22701
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abstract:BACKGROUND:Lymphangioma circumscriptum (LC) is a rare, benign, vascular malformation of dilated superficial lymphatic channels. Treatment is typically undertaken for cosmetic reasons or complications such as fluid drainage, pain, and infection risk that can negatively impact quality of life. Management of LC remains ch...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVES:Pores in the sclera are a candidate pathway for aqueous transport and therefore can be utilized to decrease the intraocular pressure (IOP) in glaucomatous eyes. Since pore formation is a well-known mechanism for stress relaxation in solids, laser-induced creation of pores in cartilage increase...
journal_title:Lasers in surgery and medicine
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abstract:BACKGROUND AND OBJECTIVE:This work evaluates the application of a 810 nm diode laser operating in the range of 400-1,200 mW for bacterial reduction at periodontal treatment. The aim of this study is to examine the immediate effect of the diode medium power laser in reducing the bacterial concentration at periodontal po...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20039
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abstract:BACKGROUND AND OBJECTIVE:Photodynamic therapy (PDT) has been used as a therapeutic alternative to treat periodontitis, especially in challenging sites that require additional periodontal therapy such as residual pockets. The aim of this split-mouth randomized trial was to evaluate the microbiological and clinical effec...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
doi:10.1002/lsm.22449
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Local recurrence after surgical resection for breast cancer is a significant problem and is often not controlled by radiation or chemotherapy treatments. Local recurrence is thought to be, at least in part, due to residual disease, and/or due to the contamination of the surgical field during re...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The conventional pulsed-dye laser (wavelength 585 nm, pulse duration 0.5 milliseconds) is seen as the standard treatment for port wine stains (PWS). Using the pulsed-dye laser at wavelengths of 590, 595, and 600 nm and at varying pulse durations of 1.5-40 milliseconds is one of the newest deve...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/lsm.20003
更新日期:2004-01-01 00:00:00
abstract::Using an optically shielded fiber optic laser catheter, the amount of gas produced when firing an argon ion laser into 0.9% saline solution or blood alone and into atheromatous aorta in either a blood or 0.9% saline medium was quantitated. Energies from 0.25 to 4 joules (J) were used at powers of 2, 5, and 8 W. We fou...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900080113
更新日期:1988-01-01 00:00:00
abstract::During a ten-year period 642 abdominal hollow organ resections have been performed by means of a new, original technique--that is, CO2 laser irradiation combined with specially designed instrumentation. This resulted in a remarkable decrease in postoperative morbidity and mortality. The article describes the laser pro...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900070402
更新日期:1987-01-01 00:00:00
abstract::The fourth harmonic wavelength (266 nm) of a neodymium YAG laser was used to cut precise grooves on the surface of the human cornea. Well-controlled cuts were made using the laser operating at 1.3 kHz. The width of the grooves was 2-3 micron. The depth could be controlled by varying the amount of laser exposure. ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900050405
更新日期:1985-01-01 00:00:00
abstract::Previous investigators, using relatively high irradiance levels, have been unable to demonstrate viable tissue in the plume during carbon dioxide laser vaporization. Our study was undertaken to reinvestigate this possibility, particularly at the lower irradiance levels that are currently in clinical use. Fresh post-mo...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900060117
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In this study, methylene blue-mediated photodynamic therapy (MB-PDT) was used as a possible alternative method for the treatment of oral lichen planus (OLP). STUDY DESIGN/MATERIALS AND METHODS:Thirteen patients with 26 OLP lesions were enrolled in this study. Patients were instructed to gargl...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20278
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Concerning current clinical practice, laser-assisted lipoplasty is still secondary to other procedures. In order to evaluate effects of thermal interaction with fatty-tissue, a near infrared diode laser was examined under reproducible conditions. METHODS:Based on optical spectroscopy of fatty-...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20602
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In recent years, clinical low-intensity laser therapy practice has used pulsed radiation, mainly from semiconductor lasers. Experimental works devoted to the study of relationships between biological and clinical effects and parameters of pulsed radiation are practically absent. STUDY DESIGN/M...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/(sici)1096-9101(1997)21:5<485::aid-lsm11>3
更新日期:1997-01-01 00:00:00
abstract::The potential problem of rethrombosis after laser recanalization was studied in 16 thrombus-occluded canine femoral arteries. Balloon de-endothelialization and thrombin-human blood injection produced adherent, completely occlusive thrombi 4.13 +/- 1.54 cm in length; laser exposure of the thrombi occurred at 18.35 +/- ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900050311
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Autofluorescence (AF) emission is an intrinsic parameter that can provide real-time information on morpho-functional properties of biological tissue, being strictly related with their biochemical composition and structural organization. The diagnostic potentials of AF-based techniques have been...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:Dental composite restorative materials are color matched to the tooth and are difficult to remove by mechanical means without excessive removal or damage to peripheral enamel and dentin. Lasers are ideally suited for selective ablation to minimize healthy tissue loss when replacing existing restorations, seal...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.21111
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Reflectance confocal microscopy (RCM) is a developing approach for noninvasive detection of oral lesions with label-free contrast and cellular-level resolution. For access into the oral cavity, confocal microscopes are being configured with small-diameter telescopic probes and small objective lenses. However...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.23090
更新日期:2019-05-08 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Whether light emitting diode (LED) irradiation has effects on "beta-amyloid (A beta) induced apoptosis," a leading hypothesis of the cause of Alzheimer's disease (AD), or not? STUDY DESIGN/MATERIALS AND METHODS:Monolayer cell cultures of PC12 were subjected to A beta or/and LED irradiation at...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.10216
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Most women with early stage breast cancer have the option of breast conserving therapy, which involves a partial mastectomy for removal of the primary tumor, usually followed by radiotherapy. The presence of tumor at or near the margin is strongly correlated with the risk of local tumor recurre...
journal_title:Lasers in surgery and medicine
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doi:10.1002/lsm.20865
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Nanotechnology may increase the speed of penetration into the skin. This study evaluated the efficacy, safety, and pharmacokinetics of a novel topical anesthetic nanocapsule formulation (2 g) containing 2.5% lidocaine and 2.5% prilocaine (nanorap-test formulation) compared to placebo (control ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
doi:10.1002/lsm.23071
更新日期:2019-09-01 00:00:00
abstract::Methods used to revascularize ischemic myocardium have included arterial reconstruction, coronary artery bypass grafting, providing direct circulation from the intraventricular chamber, and techniques to promote collateral circulation. Ventricular channels from the epicardial surface through the endocardium are readil...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900030307
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Helium plasma skin regeneration (PSR) is a novel skin rejuvenation technology with significant differences compared with nitrogen PSR technology but that may exert similar skin tissue effects. Study objectives included a comparison of acute and chronic skin tissue changes among the two plasmas...
journal_title:Lasers in surgery and medicine
pub_type:
doi:10.1002/lsm.23167
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Optical coherence tomography (OCT) provides ultrahigh-resolution imaging of tissues within a depth of a few millimeters, whereas ultrasonography provides good imaging further below the surface. We aimed to develop a minimally invasive rabbit model of VX2 laryngeal cancer, suitable for these two...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22409
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Repair of peripheral nerve injuries remains a major challenge in restorative medicine. Effective therapies that can be used in conjunction with surgical nerve repair to improve nerve regeneration and functional recovery are being actively investigated. It has been demonstrated by a number of pe...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22212
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of the in vitro study was to examine the clinical efficacy of semiconductor laser periodontal pocket irradiation as an adjunct to conventional scaling and root planing. MATERIALS AND METHODS:Twenty-two healthy patients with a need of periodontal treatment (15 women, 7 men, mean age 45...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20252
更新日期:2005-12-01 00:00:00