Methylene blue-mediated photodynamic therapy: a possible alternative treatment for oral lichen planus.

Abstract:

BACKGROUND AND OBJECTIVES:In this study, methylene blue-mediated photodynamic therapy (MB-PDT) was used as a possible alternative method for the treatment of oral lichen planus (OLP). STUDY DESIGN/MATERIALS AND METHODS:Thirteen patients with 26 OLP lesions were enrolled in this study. Patients were instructed to gargle a 5% methylene blue solution in water for 5 minutes. Ten minutes later, irradiation was performed by laser light (lambda = 632 nm, light exposure dose = 120 J/cm(2)). Lesions were evaluated pre and post-operatively and at follow-up sessions by changes in sign and symptom (pain) scores, and size of lesions. RESULTS:Improvement in sign scores was achieved in 16 lesions. Four keratotic lesions disappeared completely. There was a statistically significant decrease in sign and symptom scores 1 week after treatment and at follow-up sessions up to 12 weeks. Average reduction in size of lesions was 44.3%. CONCLUSION:MB-PDT seems to be an effective alternative treatment for control of OLP. In our opinion, this preliminary result warrant further studies in order to show the efficacy of MB-PDT in control of OLP for a longer period of time.

journal_name

Lasers Surg Med

authors

Aghahosseini F,Arbabi-Kalati F,Fashtami LA,Djavid GE,Fateh M,Beitollahi JM

doi

10.1002/lsm.20278

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

33-8

issue

1

eissn

0196-8092

issn

1096-9101

journal_volume

38

pub_type

杂志文章
  • Comparison of thermal tissue effects induced by contact application of fiber guided laser systems.

    abstract:BACKGROUND AND OBJECTIVES:Laser light of various wavelengths is being used for surgical procedures in otolaryngology. Apart from well-known fiber guided laser systems such as Nd:YAG- and Ho:YAG-lasers, newly developed diode-laser systems of different wavelengths have recently become popular in surgery. In order to comp...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.10199

    authors: Janda P,Sroka R,Mundweil B,Betz CS,Baumgartner R,Leunig A

    更新日期:2003-01-01 00:00:00

  • Low level laser irradiation stimulates mitochondrial membrane potential and disperses subnuclear promyelocytic leukemia protein.

    abstract:BACKGROUND AND OBJECTIVES:Low level laser irradiation (LLLI) is used to promote wound healing. Molecularly it is known to stimulate mitochondrial membrane potential (MMP), cytokine secretion, and cell proliferation. This study was designed to determine the influence of LLLI on the kinetics of MMP stimulation and decay,...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20108

    authors: Gavish L,Asher Y,Becker Y,Kleinman Y

    更新日期:2004-01-01 00:00:00

  • Ultrastructural changes elicited by a non-ablative wrinkle reduction laser.

    abstract:BACKGROUND AND OBJECTIVES:Cosmeceuticals, chemical peels and collagen injections are used to rejuvenate skin, but none of these methods is effective or permanent. Recently, laser resurfacing has been found to be effective, but the incidence of side effects is relatively high. Two years ago, the non-ablative wrinkle red...

    journal_title:Lasers in surgery and medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/lsm.10119

    authors: Omi T,Kawana S,Sato S,Honda M

    更新日期:2003-01-01 00:00:00

  • Effects of Er:YAG and Nd:YAG laser irradiation on radicular dentine permeability using different irrigating solutions.

    abstract:BACKGROUND AND OBJECTIVES:To evaluate the effect of Er:YAG and Nd:YAG laser on radicular dentine permeability when using distilled and deionized water and 1% NaClO as irrigating solutions. STUDY DESIGN/MATERIALS AND METHODS:Thirty human maxillary canines were divided randomly into six groups. The root canals were inst...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.10214

    authors: Brugnera A Jr,Zanin F,Barbin EL,Spanó JC,Santana R,Pécora JD

    更新日期:2003-01-01 00:00:00

  • Thulium laser-assisted endoscopic third ventriculostomy: Determining safe laser settings using in vitro model and 2 year follow-up results in 106 patients.

    abstract:BACKGROUND AND OBJECTIVE:Endoscopic third ventriculostomy is used to treat hydrocephalus. Different laser wavelengths have been proposed for laser-assisted endoscopic third ventriculostomies over the last decades. The aim of this study was to evaluate Thulium laser endoscopic third ventriculostomy heat penetration in t...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22779

    authors: de Boorder T,Brouwers HB,Noordmans HJ,Woerdeman PA,Han KS,Verdaasdonk RM

    更新日期:2017-12-07 00:00:00

  • Treatment of distal ureteral tumors using endoscopic argon photoirradiation.

    abstract::This is the first report on the use of endoscopic argon photoirradiation to treat patients with low-grade ureteral tumors involving the distal ureter. Using a rigid ureteropyeloscope, a 300 mu or 600 mu quartz fiber, and 5 watts (W) of power in a continuous-wave mode, the lesions were ablated without complication. Pat...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900120506

    authors: Johnson DE

    更新日期:1992-01-01 00:00:00

  • In vitro study of the variable square pulse Er:YAG laser cutting efficacy for apicectomy.

    abstract:BACKGROUND AND OBJECTIVES:Variable square pulse (VSP) Er:YAG laser should be quicker than older Er:YAG lasers. The objectives were: (1) comparison of VSP laser and mechanical handpiece efficacy for apicectomy and (2) determination of optimal pulse width/energy/frequency combination. STUDY DESIGN/MATERIALS AND METHODS:...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20168

    authors: Grgurević J,Grgurević L,Miletić I,Karlović Z,Krmek SJ,Anić I

    更新日期:2005-06-01 00:00:00

  • Protoporphyrin IX fluorescence and photobleaching during interstitial photodynamic therapy of malignant gliomas for early treatment prognosis.

    abstract:BACKGROUND AND OBJECTIVE:Interstitial photodynamic therapy (iPDT) of non-resectable recurrent glioblastoma using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has shown a promising outcome. It remained unclear, however, to what extent inter- and intra-tumoural differences of PpIX concentrations influence...

    journal_title:Lasers in surgery and medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/lsm.22126

    authors: Johansson A,Faber F,Kniebühler G,Stepp H,Sroka R,Egensperger R,Beyer W,Kreth FW

    更新日期:2013-04-01 00:00:00

  • Injuries as an adverse reaction to clinically used laser devices.

    abstract::Since the first use of lasers in ophthalmology in the early 1960s, applications for the medical laser have been found in many medical specialties. Despite their increasing usefulness, lasers have been reported to induce injuries. Few studies have tried to quantify the number of injuries caused by the clinical use of l...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900070603

    authors: Rodriguez JG,Sattin RW

    更新日期:1987-01-01 00:00:00

  • 193 nm excimer laser ablation of bone.

    abstract::The argon fluoride excimer laser is investigated as a cutting-ablating tool for bone surgery. Quantitative measurements are presented for various fluences of laser energy and number of pulses. Histological data are presented that demonstrate the minimal damage to the surrounding material from the laser interaction. Co...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900110111

    authors: Lustmann J,Ulmansky M,Fuxbrunner A,Lewis A

    更新日期:1991-01-01 00:00:00

  • Laser threshold and cell damage mechanism for intravascular photoacoustic imaging.

    abstract:OBJECTIVES:Intravascular photoacoustic (IVPA) imaging is being developed to image atherosclerotic plaques, a leading cause of morbidity and mortality in the United States. However, the safety of this imaging modality, which requires repeated irradiation with short laser pulses, has not yet been investigated. This study...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.23026

    authors: Sowers T,VanderLaan D,Karpiouk A,Donnelly EM,Smith E,Emelianov S

    更新日期:2018-10-10 00:00:00

  • Enhanced cell death in NR-S1 tumor by photodynamic therapy: possible involvement of Fas and Fas ligand system.

    abstract:BACKGROUND AND OBJECTIVES:To investigate the effect of photodynamic therapy (PDT) on cell death in malignant tumor tissue, the frequency of terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL)-positive cells and the possible involvement of Fas and Fas ligand system were evaluated. STUDY DESIGN...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/1096-9101(2000)26:5<449::aid-lsm4>3.0.co;2

    authors: Yokota T,Ikeda H,Inokuchi T,Sano K,Koji T

    更新日期:2000-01-01 00:00:00

  • Measurement of thermal effects on the optical properties of prostate tissue at wavelengths of 1,064 and 633 nm.

    abstract:BACKGROUND AND OBJECTIVE:The extent of thermal injury during laser prostatectomy is dependent on the light distribution in laser-irradiated tissue. As tissue is irradiated, the optical properties change as a function of temperature due to an alteration of molecular and cellular structure. The purpose of the present stu...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9101(1999)24:1<38::aid-lsm7>3.0

    authors: Nau WH,Roselli RJ,Milam DF

    更新日期:1999-01-01 00:00:00

  • Stone/tissue differentiation for Holmium laser lithotripsy using autofluorescence: Clinical proof of concept study.

    abstract:BACKGROUND AND OBJECTIVES:Holmium laser lithotripsy is the gold standard for intracorporeal fragmentation of urinary calculi. Usually, a visible beam is superimposed on the IR treatment laser as an aiming beam to guide the surgeon. In vitro tests showed that this aiming beam (532 nm, power <1 mW) excites strong fluores...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22611

    authors: Lange B,Jocham D,Brinkmann R,Cordes J

    更新日期:2017-04-01 00:00:00

  • Laser-induced thermal events in empty and pulp-filled dental pulp chambers.

    abstract:BACKGROUND AND OBJECTIVE:The purpose of this investigation was to evaluate: 1. thermal events during laser irradiation @2.1 microns of the pulp; 2. whether these effects are adequately modeled using an empty pulp chamber/root canal. STUDY DESIGN/MATERIALS AND METHODS:In extracted human teeth, pulpal access was prepare...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9101(1998)22:1<46::aid-lsm11>3.

    authors: Chang JC,Wilder-Smith P

    更新日期:1998-01-01 00:00:00

  • Ventricular remodeling after acute myocardial infarction: effect of low-intensity laser irradiation.

    abstract:BACKGROUND AND OBJECTIVE:Low-intensity laser irradiation is claimed to enhance wound healing. Healing after myocardial infarction results in ventricular enlargement and wall thinning. If laser treatment accelerated cardiac healing, we speculated that ventricular remodeling would be attenuated. STUDY DESIGN/MATERIALS A...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/1096-9101(2000)27:1<29::aid-lsm4>3.0.co;2-

    authors: Whittaker P,Patterson MJ

    更新日期:2000-01-01 00:00:00

  • Synthesis and in vitro PDT evaluation of new porphyrins containing meso-epoxymethylaryl cationic groups.

    abstract:OBJECTIVES:Photodynamic therapy (PDT) is an effective cancer treatment that uses photosensitizers, light, and oxygen to destroy malignant cells. Porphyrins, and in particular the cationic derivatives, are the most investigated photosensitizers for PDT. In this context, it is important to study new methodologies to deve...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22824

    authors: Carneiro J,Gonçalves A,Zhou Z,Griffin KE,Kaufman NEM,Vicente MDGH

    更新日期:2018-07-01 00:00:00

  • Laser modulation of angiogenic factor production by T-lymphocytes.

    abstract:BACKGROUND AND OBJECTIVE:In previous investigations, small variations in the energy densities of low level light therapy (LLLT) were found to produce significant differences in the proliferation of resting T-lymphocytes in vitro. Pulsing these cells with mitogen in addition to laser therapy produced inhibitory effects ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9101(2000)26:4<357::aid-lsm3>3.

    authors: Agaiby AD,Ghali LR,Wilson R,Dyson M

    更新日期:2000-01-01 00:00:00

  • In vitro study examining the effect of sub-lethal QS 755 nm lasers on the expression of p16INK4a on melanoma cell lines.

    abstract:BACKGROUND AND OBJECTIVES:Q-switched lasers had been used in the treatment of lentigo maligna but their role remains controversial. While previous studies have addressed the change in adhesion molecule expression after sub-lethal laser damage, no study has addressed the impact of sub-lethal laser damage at a molecular ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.10118

    authors: Chan HH,Xiang L,Leung JC,Tsang KW,Lai KN

    更新日期:2003-01-01 00:00:00

  • Renal evaluation after CUSA plus Nd:YAG laser for partial nephrectomy.

    abstract::A technique for partial nephrectomy using a combination of an Ultrasonic Surgical Aspirator and a neodymium:YAG laser provided better hemostasis and decreased total operative time compared to standard methods. Delayed hemorrhage was not seen, and thermal damage to the remaining renal parenchyma was minimal. ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900060210

    authors: Landau ST,Wood TW,Melzer RB,Lee RG,Smith JA Jr

    更新日期:1986-01-01 00:00:00

  • Effect of low-level laser therapy (LLLT) on viscoelasticity of the contracted knee joint: comparison with whirlpool treatment in rats.

    abstract:BACKGROUND AND OBJECTIVE:The purpose of this study was to compare the effect of Low-Level Laser Therapy (LLLT) with sham and whirlpool treatment on the contracted knee joint in rat. STUDY DESIGN/MATERIALS AND METHODS:Forty-eight Wistar rats were operated on to immobilize knee joint, and 1 week after operation they wer...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9101(1998)22:2<81::aid-lsm3>3.0

    authors: Usuba M,Akai M,Shirasaki Y

    更新日期:1998-01-01 00:00:00

  • Scanning laser system for photodynamic therapy of choroidal neovascularization.

    abstract:BACKGROUND AND OBJECTIVES:In order to improve selectivity of photodynamic therapy (PDT) to choroidal neovascularization (CNV) associated with age-related macular degeneration, a laser scanning technique was applied to perform focal laser irradiation to the retina, and the occlusion effects of a new device to the chorio...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.10056

    authors: Obana A,Gohto Y

    更新日期:2002-01-01 00:00:00

  • Gross and microscopic changes in the viscera induced by photodynamic therapy applied to the lower abdomen of intact rats.

    abstract::Photodynamic therapy (PDT) is a promising approach to the treatment of cancer. Preferential retention of the photosensitizer by malignant tissue has been considered a hallmark of this treatment modality. However, photosensitivity can be observed in normal, non-neoplastic tissues, and the present study investigated the...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900110110

    authors: Chazen MD,Baggs RB,Gibson SL,Albert MS,Hilf R

    更新日期:1991-01-01 00:00:00

  • Local physiological changes during photodynamic therapy.

    abstract:BACKGROUND AND OBJECTIVE:Herein an overview is provided of the causes, consequences, and significance of photodynamic therapy (PDT)-mediated effects on tumor oxygenation and blood flow during illumination. STUDY DESIGN/MATERIALS AND METHODS:Techniques particularly valuable to this research have included tissue oxygen ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,评审

    doi:10.1002/lsm.20355

    authors: Busch TM

    更新日期:2006-06-01 00:00:00

  • Reduced in vivo local recurrence with contact neodymium: Yttrium-Aluminium-Garnet (Nd:YAG) laser scalpels.

    abstract:BACKGROUND AND OBJECTIVE:Local recurrence after surgical resection for breast cancer is a significant problem and is often not controlled by radiation or chemotherapy treatments. Local recurrence is thought to be, at least in part, due to residual disease, and/or due to the contamination of the surgical field during re...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900170406

    authors: Maker VK,Elseth KM,Radosevich JA

    更新日期:1995-01-01 00:00:00

  • Practical models for light distribution in laser-irradiated tissue.

    abstract::The distribution of light in laser-irradiated biological medium is computed using four different procedures. Values computed with Beer's law of attenuation, Kubelka-Munk theory, the diffusion approximation, and a seven-flux model are compared. The proper conditions for using each model are discussed. ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900060603

    authors: Welch AJ,Yoon G,van Gemert MJ

    更新日期:1987-01-01 00:00:00

  • The Use of a 1,540 nm Fractional Erbium-Glass Laser in Treatment of Alopecia Areata.

    abstract:BACKGROUND AND OBJECTIVES:Varieties of laser and light sources have been tried for treatment of alopecia areata (AA) and some success has been reported. To assess the effectiveness of 1,540  nm fractional erbium-glass laser in treatment of AA. STUDY DESIGN/MATERIALS AND METHODS:The patches of AA were divided into two ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.23133

    authors: Al-Dhalimi MA,Al-Janabi MH,Abd Al Hussein RA

    更新日期:2019-12-01 00:00:00

  • A light emitting diode (LED) based spatial frequency domain imaging system for optimization of photodynamic therapy of nonmelanoma skin cancer: quantitative reflectance imaging.

    abstract:BACKGROUND:Photodynamic therapy (PDT) offers the potential for enhanced treatment of nonmelanoma skin cancer (NMSC) with minimal scarring. Yet, PDT has not achieved consistent long term effectiveness to gain widespread clinical acceptance for treatment of skin cancer. Therapeutic response varies between practitioners, ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22139

    authors: Saager RB,Cuccia DJ,Saggese S,Kelly KM,Durkin AJ

    更新日期:2013-04-01 00:00:00

  • Laser recannalization of atheromatous vessels using fiber optics.

    abstract::A laser endoscope was devised using optic fibers in order to provide a means of visualization and removal of atheromatous plaques from arteries in cadavers and experimental animals. Atheromatous plaques were satisfactorily lased off in a few seconds, although contraction of lased vessels was observed. A self-focusing ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900040408

    authors: Ward H

    更新日期:1984-01-01 00:00:00

  • Intradermally focused infrared laser pulses: thermal effects at defined tissue depths.

    abstract:BACKGROUND AND OBJECTIVES:To produce controlled, spatially confined thermal effects in dermis. STUDY DESIGNS/MATERIALS AND METHODS:A 1 W, 1,500 nm fiber-coupled diode laser was focused with a high numerical aperture (NA) objective to achieve a tight optical focus within the upper dermis of skin held in contact with a ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20142

    authors: Khan MH,Sink RK,Manstein D,Eimerl D,Anderson RR

    更新日期:2005-04-01 00:00:00