Gross and microscopic changes in the viscera induced by photodynamic therapy applied to the lower abdomen of intact rats.

abstract：:Hematoporphyrin derivative (HpD) is a photoactive, oncophilic substance that produces cutaneous photosensitivity as its only significant side effect. Twenty-three patients who received systemic HpD and the usual light-avoidance precautions were studied prospectively to determine the incidence and severity of cutaneous...

journal_title：Lasers in surgery and medicine

authors： Wooten RS,Smith KC,Ahlquist DA,Muller SA,Balm RK

更新日期：1988-01-01 00:00:00

abstract：:Serial gross and histopathologic examinations of the prostate following interstitial laser prostatectomy in the canine model demonstrated distinct zonal thermal changes around the entire active area of the interstitial thermal therapy (ITT) fiber. A large, well-demarcated area of acute coagulative necrosis immediately...

journal_title：Lasers in surgery and medicine

authors： Johnson DE,Cromeens DM,Price RE

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Alternative treatments are needed to achieve consistent and more complete port wine stain (PWS) removal, especially in darker skin types; photodynamic therapy (PDT) is a promising alternative treatment. To this end, we previously reported on Talaporfin Sodium (TS)-mediated PDT. It is essential ...

journal_title：Lasers in surgery and medicine

authors： Moy WJ,Yao J,de Feraudy SM,White SM,Salvador J,Kelly KM,Choi B

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cosmeceuticals, chemical peels and collagen injections are used to rejuvenate skin, but none of these methods is effective or permanent. Recently, laser resurfacing has been found to be effective, but the incidence of side effects is relatively high. Two years ago, the non-ablative wrinkle red...

journal_title：Lasers in surgery and medicine

authors： Omi T,Kawana S,Sato S,Honda M

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:During transmyocardial laser revascularization (TMLR), multiple microembolic signals (MES) can be detected in cerebral arteries. We sought to characterize composition and clinical relevance of these MES and to evaluate strategies to reduce cerebral microembolization during TMLR. STUDY DESIGN/...

journal_title：Lasers in surgery and medicine

authors： Gerriets T,Grossherr M,Misfeld M,Nees U,Reusche E,Stolz E,Sievers HH,Kaps M,Kraatz EG

更新日期：2004-01-01 00:00:00

abstract：:Heat-induced oxygen tension changes in RIF-1 tumors in C3H male mice were analyzed in an attempt to correlate these changes with tumor response to Nd:YAG laser heating. A low power, microprocessor-controlled Nd:YAG laser was used to superficially heat 250-300 mm3 tumors to base temperatures of 44, 45, 46, or 48 degree...

journal_title：Lasers in surgery and medicine

authors： Fahy AK,Waldow SM

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:A port wine stain (PWS) is a type of capillary vascular malformation composed of malformed, dilated blood vessels within the papillary and reticular dermis. Currently, pulsed dye laser (PDL) is considered the therapeutic gold standard, although greater than 90% of lesions may be refractory to t...

journal_title：Lasers in surgery and medicine

authors： Griffin TD Jr,Foshee JP,Finney R,Saedi N

更新日期：2016-02-01 00:00:00

abstract：:Interstitial thermotherapy using Nd:YAG-laser induced hyperthermia is a new stereotactic method for the treatment of brain tumors in poorly accessible regions. To provide a basis for the underlying tissue alterations, we have analyzed the spatial and temporal pattern of interstitial laser hyperthermia lesions in the n...

journal_title：Lasers in surgery and medicine

authors： Schober R,Bettag M,Sabel M,Ulrich F,Hessel S

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To produce controlled, spatially confined thermal effects in dermis. STUDY DESIGNS/MATERIALS AND METHODS:A 1 W, 1,500 nm fiber-coupled diode laser was focused with a high numerical aperture (NA) objective to achieve a tight optical focus within the upper dermis of skin held in contact with a ...

journal_title：Lasers in surgery and medicine

authors： Khan MH,Sink RK,Manstein D,Eimerl D,Anderson RR

更新日期：2005-04-01 00:00:00

abstract：:In this study, we examined short-term strength and histology of experimental argon and CO2 laser-welded and control-sutured enterotomies in a rabbit model. Longitudinal 1.0-cm enterotomies were closed with the argon laser at 0.5 (n = 10) or 1.0 (n = 10) W power and a spot diameter of 2.8 mm resulting in energy fluence...

journal_title：Lasers in surgery and medicine

authors： Vlasak JW,Kopchok GE,White RA

更新日期：1988-01-01 00:00:00

abstract：:Percutaneous endoscopic approaches to cholelithiasis would be facilitated by methods for welding gallbladder tissues. We evaluated the bursting pressure and histologic appearance of canine gallbladder tissue welded with a thulium-holmium-chromium:YAG (THC:YAG) laser producing a 2.15 microns pulsed output. The tissue a...

journal_title：Lasers in surgery and medicine

authors： Popp HW,Oz MC,Bass LS,Chuck RS,Trokel SL,Treat MR

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interstitial photodynamic therapy (iPDT) of non-resectable recurrent glioblastoma using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has shown a promising outcome. It remained unclear, however, to what extent inter- and intra-tumoural differences of PpIX concentrations influence...

journal_title：Lasers in surgery and medicine

authors： Johansson A,Faber F,Kniebühler G,Stepp H,Sroka R,Egensperger R,Beyer W,Kreth FW

更新日期：2013-04-01 00:00:00

abstract：:This article reviews the principle uses of ophthalmic lasers, providing historical background with an emphasis on new applications and areas of investigation. Ophthalmic photocoagulation was the first medical laser application and has restored or maintained vision in millions of people. More recently, photodisruption ...

journal_title：Lasers in surgery and medicine

authors： Krauss JM,Puliafito CA

更新日期：1995-01-01 00:00:00

abstract：:This study was designed to examine the acute response of normal arterial wall to pulsed laser irradiation. Irradiation with an Excimer or a Holmium YAG laser was performed in 15 normal iliac sites of 8 male New Zealand white rabbits. The excimer laser was operated at 308 nm, 25 Hz, 50 mJ/mm2/pulse, and 135 nsec/pulse ...

journal_title：Lasers in surgery and medicine

authors： Nakamura F,Kvasnicka J,Levame M,Lange F,Bousbaa H,Geschwind HJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Lasers can be used to modify the chemical composition of dental enamel to increase the bond strength to restorative materials and to render the mineral phase more resistant to acid dissolution. Previous studies have suggested a synergistic relationship between CO(2) laser irradiation and fluor...

journal_title：Lasers in surgery and medicine

authors： Wheeler CR,Fried D,Featherstone JD,Watanabe LG,Le CQ

更新日期：2003-01-01 00:00:00

abstract：:Diagnostic endoscopy has generally been done under intravenous sedation. Diazepam and meperidine are the two most frequent drugs used. Even though these drugs produce sedation, analgesia, and amnesia, they do not provide a quiet field. Therapeutic laser endoscopy requires a quiet field. We conclude that an anesthesiol...

journal_title：Lasers in surgery and medicine

authors： Lichtiger M,Russin DJ

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Femtosecond (fs) Laser Ionisation Mass Spectrometry (fs-LIMS) on colon tissues are described and investigated using ionization/fragmentation processes in details to present a new application in this study. Linear Time of Flight (L-TOF) mass analyzer was utilized to investigate paraffin-embedded human tissue ...

journal_title：Lasers in surgery and medicine

authors： Gündoğdu Y,Alptekin H,Karabağlı P,Şahin M,Kilic HŞ

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Optical energy-based devices, including intense pulsed light (IPL) and potassium titanyl phosphate (KTP) lasers achieve reduction of pigmented and vascular lesions in a relatively similar number of treatments. This study aimed to evaluate the efficacy and safety of an IPL with a "KTP-like" filter emitting a ...

journal_title：Lasers in surgery and medicine

authors： Friedmann DP,Peterson JD

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hypertrophic scarring and rigid scar contracture are disorders of wound healing for which there is presently no effective therapy. The dermal fibroblast plays a major role in scar fibrillogenesis and contracture. The objective of this study was to establish a selective and effective method to d...

journal_title：Lasers in surgery and medicine

authors： Strong LH,Berthiaume F,Yarmush ML

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Recent studies have sought to utilize diode laser "micropulsing" in order to preserve therapeutic efficacy of retinal photocoagulation while minimizing pain and subjacent tissue injury. A model for the transient thermal tissue response to continuous and micropulsed diode laser output is present...

journal_title：Lasers in surgery and medicine

authors： Berger JW

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Chronic sun-exposure results in five main changes to exposed skin: telangiectasia, hyperpigmentation, rhytides, enlarged pores, and sagging skin. Various laser and non-laser modalities have been used to improve sun-damaged skin. The pulsed-dye laser (PDL) has an unparalleled safety record and ...

journal_title：Lasers in surgery and medicine

authors： Bernstein EF

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Erbium lasers are potential tools to remove caries and dental hard tissue but bond strengths of composites to those preparations are reported to be lower than conventional methods. The purpose of this study was to evaluate the effect of mechanical excavation and/or chemical alteration on bond s...

journal_title：Lasers in surgery and medicine

authors： Obeidi A,McCracken MS,Liu PR,Litaker MS,Beck P,Rahemtulla F

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Postoperative scarring after thyroidectomy is a problem for both patients and clinicians. Recently, both non-ablative and ablative fractional laser (NFL and AFL) systems have attracted attention as potential therapies for the revision of thyroidectomy scars. The present split-scar study was des...

journal_title：Lasers in surgery and medicine

authors： Shin JU,Gantsetseg D,Jung JY,Jung I,Shin S,Lee JH

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Nonmelanoma skin cancers, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common skin cancers, presenting nearly as many cases as all other cancers combined. The current gold-standard for clinical diagnosis of these lesions is histopathologic examination, a...

journal_title：Lasers in surgery and medicine

authors： Lieber CA,Majumder SK,Ellis DL,Billheimer DD,Mahadevan-Jansen A

更新日期：2008-09-01 00:00:00

abstract：:Near-infrared radiation from a Nd:YAG laser at 1,064 nm was used interstitially or superficially to induce hyperthermia in RIF-1 tumors in C3H male mice. A single 600-microns quartz fiber with a 0.5-cm cylindrical diffusor or a weakly diverging microlens at its distal end was used to deliver laser energy to tumors in ...

journal_title：Lasers in surgery and medicine

authors： Waldow SM,Russell GE,Wallner PE

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The nonablative application of holmium:yttrium-aluminum-garnet (Ho:YAG) laser energy to the joint capsule of patients with glenohumeral instability has been found to shrink capsular tissue and to help stabilize the joint. The purpose of this study was to evaluate the effect of nonablative laser...

journal_title：Lasers in surgery and medicine

authors： Hayashi K,Nieckarz JA,Thabit G 3rd,Bogdanske JJ,Cooley AJ,Markel MD

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Q-switched lasers had been used in the treatment of lentigo maligna but their role remains controversial. While previous studies have addressed the change in adhesion molecule expression after sub-lethal laser damage, no study has addressed the impact of sub-lethal laser damage at a molecular ...

journal_title：Lasers in surgery and medicine

authors： Chan HH,Xiang L,Leung JC,Tsang KW,Lai KN

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The difficulties typically encountered in studying the effects of restorations on tooth reinforcement are often due to the 3-dimensional (3D) nature of deformation. Therefore, electronic 3D-Speckle-Interferometry (3D-ESPI) was used to assess the impact of different restorative materials on the...

journal_title：Lasers in surgery and medicine

authors： Lang H,Rampado M,Müllejans R,Raab WH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The Holmium: YAG (Ho: YAG) laser has been used for the ablation of prolapsed discs but alternative techniques are available, and this application remains controversial. It also has potential for the decompression of nerve roots within narrowed foraminae with the technique of endoscopic laser fo...

journal_title：Lasers in surgery and medicine

authors： Hafez MI,Zhou S,Coombs RR,McCarthy ID

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Low-intensity laser irradiation (LILI) has been used to modulate a variety of biological processes, including diabetic wound healing. The mechanism of action is thought to exist primarily with the mitochondria. This study aimed to determine the effect of irradiation on normal, diabetic, and isc...

journal_title：Lasers in surgery and medicine

authors： Houreld NN,Masha RT,Abrahamse H

更新日期：2012-07-01 00:00:00