当前位置： SCI文献检索 > LASERS IN SURGERY AND MEDICINE期刊下所有文献 > The new-generation, high-energy, 595-nm, long pulse-duration pulsed-dye laser improves the appearance of photodamaged skin.

The new-generation, high-energy, 595-nm, long pulse-duration pulsed-dye laser improves the appearance of photodamaged skin.

Abstract：

BACKGROUND AND OBJECTIVES:Chronic sun-exposure results in five main changes to exposed skin: telangiectasia, hyperpigmentation, rhytides, enlarged pores, and sagging skin. Various laser and non-laser modalities have been used to improve sun-damaged skin. The pulsed-dye laser (PDL) has an unparalleled safety record and an ideal wavelength for treating the signs of photodamage. In this study, we investigate the ability of the long pulse-duration PDL to improve the appearance of photodamaged skin. STUDY DESIGN/MATERIALS AND METHODS:Ten subjects with cutaneous photodamage were treated with the high-energy, long pulse-duration PDL using fluences ranging from 8.0 to 10.0 J/cm(2), a 10-mm spot, and a 10-millisecond pulse-duration. Five subjects judged to have discrete solar lentigos or ephiledes were also treated to these lesions using a compression handpiece. Improvement was determined by blinded evaluation of photographs taken before and after the final treatment, and by subjects' self-evaluation 8 weeks following the final treatment. RESULTS:Subjects rated overall improvement as 65%, facial veins as 72% improved, hyperpigmentation 65% improved, enlarged pores 65% improved, and wrinkles 62% improved. Improvement was also determined by 3 physicians rating digital photographs and blinded as to which photos were pre- or post-treatment. They rated wrinkles as improved in 50% of photographs, veins as improved in 82%, diffuse redness as improved in 80%, pigmentary alterations as improved in 61.4%, and pore size as improved in 25%. CONCLUSIONS:The high-energy, long pulse-duration PDL improves photodamaged skin using non-purpuric settings.

journal_name

Lasers Surg Med

journal_title

Lasers in surgery and medicine

authors

Bernstein EF

doi

10.1002/lsm.20463

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

157-63

issue

2

eissn

0196-8092

issn

1096-9101

journal_volume

39

pub_type

杂志文章

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