Abstract：
:This study examined both the effect of variations in optical fiber tip and in light wavelength on laser-induced hyperthermia in rat brain. Normal rat brains were exposed to argon laser light (454-514.5 nm) delivered through an intracerebral end-emitting (bare-tipped) or a diffusion-emitting (sapphire-tipped) optical fiber probe. Interstitial thermistor probes recorded temperatures after thermal equilibration at varying distances from the emitting source. The end-emitting fiber produced significantly (P less than 0.05) higher elevations in tissue temperature than the diffusion-emitting fiber at the same laser power output. This is due to the smaller surface area (1.2 mm2 versus 7.8 mm2) of the end-emitting fiber, which results in a greater rate of energy delivery to tissue adjacent to the fiber tip. Changes in intracerebral temperature measurements were also recorded at similar distances from a diffusion-emitting fiber at a continuous total laser power output of 150 mW for light wavelengths of 454-514.5 nm, 700 nm, and 750 nm and at a total laser output of 1.1 W for 1,060 nm. Variations in brain tissue temperature with distance from the laser emission source were compared for each laser group with the tissue temperature profile generated by a radiofrequency (wavelength 600-625 m) interstitial probe. Similar temperature changes were found for all visible wavelengths near the probe, suggesting that the thermal response of brain adjacent to an interstitial laser fiber is primarily dependent upon the rate of energy delivery and not upon wavelength. The thermal profile versus distance from the light source depends mostly upon the level of temperature rise near the interstitial laser fiber tip and not the wavelength of laser light used. These results have important implications in interstitial applications of laser for hyperthermia and photochemotherapy.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Elias Z,Powers SK,Atstupenas E,Brown JTdoi
10.1002/lsm.1900070413subject
Has Abstractpub_date
1987-01-01 00:00:00pages
370-5issue
4eissn
0196-8092issn
1096-9101journal_volume
7pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVES:The argon laser-assisted vascular anastomosis may solve the problems of conventional sutured anastomosis, such as vascular stenosis and arrest of growth owing to a foreign-body reaction to suture material. STUDY DESIGN/MATERIALS AND METHODS:Twelve argon laser-assisted vascular anastomoses, se...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900160105
更新日期：1995-01-01 00:00:00
abstract：:Hyperthermia induced by a microwave source (2,450 MHz) was used alone and in combination with photodynamic therapy (PDT) to treat the SMT-F, EMT-6, and RIF animal tumors in vivo. PDT was administered using either Photofrin I or II as the photosensitizer and an argon-pumped tunable dye laser (630 nm) as the light sourc...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900070104
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Phototherapy plus dynamic exercise can enhance physical performance and improve health. The aim of our study was to evaluate the effect of low-level laser therapy (LLLT) associated with high intensity resistance training (HIT) on cardiac autonomic and muscle metabolic responses in rats. STUDY ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22298
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The identification of parathyroid glands can be a major problem in parathyroid surgery. The purpose of this study was to evaluate the feasibility of optical coherence tomography (OCT) in distinguishing between parathyroid tissue, thyroid tissue, lymph nodes, and adipose tissue. METHODS:Ex vivo...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22195
更新日期：2013-12-01 00:00:00
abstract：INTRODUCTION:Leg telangiectasias have been reported to have been treated with a variety of lasers. This study was designed to measure response to treatment of leg telangiectasias with a unique coupled 585 nm and 1064 nm pulse. METHODS:Sixty female patients (24-62 y.o., skin types II-IV) with leg vein varicosities were...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20972
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Transient optical nerve stimulation is a promising new non-contact, spatially precise, artifact-free neural excitation technique useful in research and clinical settings. This study evaluates safety of this pulsed infrared laser technique by histopathologic examination of stimulated peripheral ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20522
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Basal cell carcinoma (BCC) is an indolent form of skin cancer that is rarely life threatening, but can cause significant cosmetic and functional morbidity. Surgical treatments often result in disfiguring scars, while topical therapies frequently result in recurrence. The need for a more effecti...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22803
更新日期：2018-02-13 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Concerning current clinical practice, laser-assisted lipoplasty is still secondary to other procedures. In order to evaluate effects of thermal interaction with fatty-tissue, a near infrared diode laser was examined under reproducible conditions. METHODS:Based on optical spectroscopy of fatty-...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20602
更新日期：2008-02-01 00:00:00
abstract：:Seven cases of cerebral tumors (four deep-seated sovratentorial gliomas located in motor area, occipital region, parietal region and frontal region; one deep-seated cystic cerebellar spongioblastoma; one sphenoidal wing meningioma, and one spinal cord intradural tumor) were simultaneously irradiated in the same area w...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900020205
更新日期：1982-01-01 00:00:00
abstract：:This study was designed to examine the acute response of normal arterial wall to pulsed laser irradiation. Irradiation with an Excimer or a Holmium YAG laser was performed in 15 normal iliac sites of 8 male New Zealand white rabbits. The excimer laser was operated at 308 nm, 25 Hz, 50 mJ/mm2/pulse, and 135 nsec/pulse ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900130404
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The conventional pulsed-dye laser (wavelength 585 nm, pulse duration 0.5 milliseconds) is seen as the standard treatment for port wine stains (PWS). Using the pulsed-dye laser at wavelengths of 590, 595, and 600 nm and at varying pulse durations of 1.5-40 milliseconds is one of the newest deve...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1002/lsm.20003
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:While controlled thermal changes in subcutaneous tissue have been used to trigger apoptosis of fat cells and have been proven clinically efficacious, another mechanism of electromagnetic stress suggests that fat apoptosis could be achieved by a non-thermal manner as well. This animal model study investigates...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.23039
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:We reported the use of Holmium-YAG laser in the management of a foreign body impacted in the esophagus. STUDY DESIGN/PATIENTS AND METHODS:Esophagoscopy was performed on a man with a denture impacted in the esophagus. The denture was disimpacted into the stomach and fractured with Holmium-YAG l...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1997)20:4<480::aid-lsm16>3
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:Dental composite restorative materials are color matched to the tooth and are difficult to remove by mechanical means without excessive removal or damage to peripheral enamel and dentin. Lasers are ideally suited for selective ablation to minimize healthy tissue loss when replacing existing restorations, seal...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.21111
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The objective of this study was to quantitatively measure changes in the elastic moduli of rabbit nasal septal cartilage during laser heating. While the efficacy of laser cartilage reshaping has been established for use in nasal surgery, few studies have investigated the temperature-dependent ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.10176
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Postoperative scarring after thyroidectomy is a problem for both patients and clinicians. Recently, both non-ablative and ablative fractional laser (NFL and AFL) systems have attracted attention as potential therapies for the revision of thyroidectomy scars. The present split-scar study was des...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.22297
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The clinical use of lasers to cut and coagulate tissue necessitates a better understanding of how the residual thermal damage affects healing. This study was designed to evaluate the effects of varying degrees of thermal damage on the healing process. STUDY DESIGN, MATERIALS AND METHODS:Partia...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(SICI)1096-9101(1996)18:1<1::AID-LSM1>3.0.
更新日期：1996-01-01 00:00:00
abstract：OBJECTIVES:Intravascular photoacoustic (IVPA) imaging is being developed to image atherosclerotic plaques, a leading cause of morbidity and mortality in the United States. However, the safety of this imaging modality, which requires repeated irradiation with short laser pulses, has not yet been investigated. This study...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.23026
更新日期：2018-10-10 00:00:00
abstract：BACKGROUND:Patients suffering from malignant gliomas have a poor prognosis. For the surgical treatment of these tumors, 5-aminolevulinic acid (5-ALA) has become a new standard. AIMS:This review intends to provide an overview over current status, significance, limitations, and future perspectives of 5-ALA based fluores...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章,评审
doi：10.1002/lsm.22933
更新日期：2018-07-01 00:00:00
abstract：:The use of pulsed laser radiation to recanalize occluded biliary endoprostheses was examined. In vitro measurements demonstrated that a repetitively pulsed organic dye laser transmitted through a small diameter quartz fiber can recanalize an occluded stent in less than 10 sec without causing visible damage to the sten...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900070503
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Interstitial laser thermotherapy was used to treat rat liver tumours. The aim was to investigate the influence of temperature and temporary hepatic inflow occlusion on tumour growth and blood perfusion. STUDY DESIGN/MATERIALS AND METHODS:Liver tumours were treated at 44°C at the tumour border ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.21024
更新日期：2011-01-01 00:00:00
abstract：UNLABELLED:BACKGROUND AND OBJECTIVE To examine the biophysical effects of photothermal heating on herniated intervertebral discs during laser decompression surgery. STUDY DESIGN/MATERIALS AND METHODS:Ex vivo bovine nucleus pulposus specimens were irradiated with a Nd: YAG laser (lambda = 1.32 microm, 100 seconds expos...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1046
更新日期：2001-01-01 00:00:00
abstract：:The acute or emergency treatment of traumatic tattoos has been based on the principles of immediate and thorough removal of all particles. The delayed treatment of traumatic tattoos has classically been with overgrafting or dermabrasion. We developed an animal model for traumatic tattoos. Two levels of wounds were mad...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900100208
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Laryngeal lesions are usually investigated by microlaryngoscopy, biopsy, and histopathology. This study aimed to evaluate the combined use of Narrow Band Imaging (NBI) and High-Speed Imaging (HSI) in the differentiation of glottic lesions in awake patients. STUDY DESIGN:Prospective diagnostic ...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.22652
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The Holmium: YAG (Ho: YAG) laser has been used for the ablation of prolapsed discs but alternative techniques are available, and this application remains controversial. It also has potential for the decompression of nerve roots within narrowed foraminae with the technique of endoscopic laser fo...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1083
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:We sought to investigate risk factors for recurrence of vaginal intraepithelial neoplasia (VAIN) in the vaginal vault after laser vaporization. MATERIALS AND METHODS:Among 162 patients treated with laser vaporization in the vaginal vault after hysterectomy between March 1998 and August 2007, the clinical da...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20741
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:A prospective, double-blind, randomized, and controlled trial was conducted in patients with knee osteoarthritis (OA) to evaluate the efficacy of infrared low-power Gallium-Arsenide (Ga-As) laser therapy (LPLT) and compared two different laser therapy regimes. STUDY DESIGN/MATERIALS AND METHO...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1002/lsm.10236
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Fiber-assisted laser surgery has been employed as a minimally invasive method in various medical fields. In spite of multiple sweeping on tissue during laser treatments, the rate of tissue removal gradually decreases and eventually leads to longer irradiation times as well as deeper thermal inj...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22505
更新日期：2016-08-01 00:00:00
abstract：:Methods used to revascularize ischemic myocardium have included arterial reconstruction, coronary artery bypass grafting, providing direct circulation from the intraventricular chamber, and techniques to promote collateral circulation. Ventricular channels from the epicardial surface through the endocardium are readil...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900030307
更新日期：1983-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to evaluate the effectiveness of the pulsed dye laser (585 nm, 450 ms) in the treatment of sun induced wrinkles. DESIGN:Patients had one pulsed dye laser (585 nm) treatment. The treated areas were assessed by the following methods: grading of skin wrinkles at 6 weeks, 12 weeks...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1999)25:3<229::aid-lsm7>3.
更新日期：1999-01-01 00:00:00
