Abstract：
:To differentiate the contributing factors (blood or encapsulated dye) leading to the release of encapsulated dyes from liposomes after laser exposure, we initiated an in vitro experimental study. The release of encapsulated calcein was quantified under various experimental conditions in whole blood and in buffered solution containing high-density lipoprotein. Generally, the amount of dye release improved with an increase in laser power, with a maximum release of approximately 80% of encapsulated dye. Because the laser exposure was not continuous, only 80% of each sample was actually exposed. Therefore, 80% release may be thought of as total release. In a lipoprotein/buffer mixture, the 488 nm wavelength caused greater dye release than the 577 nm wavelength, because the maximum absorption of calcein is near 488 nm. The laser wavelength at 577 nm, however, caused greater release in the blood mixture, reflecting the peak absorption of hemoglobin at near 577 nm. At a 3 x higher liposome concentration, the differences in the effects of wavelengths on the release of dye from liposomes were insignificant. Although the 577 nm wavelength is an optimum wavelength for dye and drug delivery in the presence of blood, the 488 nm wavelength might also be suitable for the release of dye from the liposomes.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Khoobehi B,Char CA,Peyman GA,Schuele KMdoi
10.1002/lsm.1900100312subject
Has Abstractpub_date
1990-01-01 00:00:00pages
303-9issue
3eissn
0196-8092issn
1096-9101journal_volume
10pub_type
杂志文章abstract：:This is the first report on the use of endoscopic argon photoirradiation to treat patients with low-grade ureteral tumors involving the distal ureter. Using a rigid ureteropyeloscope, a 300 mu or 600 mu quartz fiber, and 5 watts (W) of power in a continuous-wave mode, the lesions were ablated without complication. Pat...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900120506
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:Endoscopic examination followed by tissue biopsy is the gold standard in the evaluation of lesions of the upper aerodigestive tract. However, it can be difficult to distinguish between healthy mucosa, dysplasia, and invasive carcinoma. Optical coherence tomography (OCT) is a non-invasive technique which acqui...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22632
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The use of pulsed dye laser (PDL) and fractional CO2 (FX CO2 ) laser therapy to treat and/or prevent scarring following burn injury is becoming more widespread with a number of studies reporting reduction in scar erythema and pruritus following treatment with lasers. While the majority of studi...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22702
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:This preliminary report describes a new laser-assisted treatment option for the emerging complication of bisphosphonate related osteonecrosis (BON) of the jaw. MATERIALS AND METHODS:In eight tumour patients (three women, five men) ten bony lesions in the maxilla and mandible in the course of ...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.20730
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Interstitial photodynamic therapy (iPDT) of non-resectable recurrent glioblastoma using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has shown a promising outcome. It remained unclear, however, to what extent inter- and intra-tumoural differences of PpIX concentrations influence...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.22126
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Er:YAG laser has been used for caries removal and cavity preparation, using ablative parameters. Its effect on the margins of restorations submitted to cariogenic challenge has not yet been sufficiently investigated. The aim of this study was to assess the enamel adjacent to restored Er:YAG la...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章,随机对照试验
doi：10.1002/lsm.20684
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:During transmyocardial laser revascularization (TMLR), multiple microembolic signals (MES) can be detected in cerebral arteries. We sought to characterize composition and clinical relevance of these MES and to evaluate strategies to reduce cerebral microembolization during TMLR. STUDY DESIGN/...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20030
更新日期：2004-01-01 00:00:00
abstract：:New instruments to facilitate laser operations are presented. These devices are based on the Kocher bronchocoele sound and are useful as dissecting tools and optical backstops to prevent iatrogenic injury. ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900100613
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Recently developed laser lipolysis systems have been disappointing because they require more time to remove the same amount of fat than other liposuction methods. A new Nd:YAG laser has been introduced that uses the 1,444 nm wavelength, better absorbed by fat. STUDY DESIGN/MATERIALS AND METHO...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20786
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:This laboratory animal study is a comparison of Nd:YAG 1064 nm and diode 810 nm laser wavelengths in brain interstitial laser photocoagulation (ILP). Specific goals were to identify potential complications and physical characteristics of the thermal damage at both wavelengths prior to undertaki...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1997)21:1<50::aid-lsm8>3.0
更新日期：1997-01-01 00:00:00
abstract：:Laser physiology has shown that while wound healing is generally excellent after laser impaction, it nevertheless is delayed. It is thought that this factor may be important in the treatment of hypertrophic and keloid scars. These scars have been treated in a variety of ways with the laser, and the results, which have...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900030402
更新日期：1984-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Fifty percent human albumin solder significantly improves weld strength when compared to lower concentrations [Wright et al., ASLMS meeting, April, 1995]. We developed a method for preparing 50% human albumin that may be considered compatible for clinical applications. STUDY DESIGN/MATERIALS A...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(SICI)1096-9101(1996)19:1<2::AID-LSM1>3.0.
更新日期：1996-01-01 00:00:00
abstract：:A low-energy Nd:YAG laser was used to irradiate extracted human teeth coated with a black energy-absorbent laser initiator in a study to determine the extent of the morphologic changes produced in the enamel surface. The laser initiator was applied to a cleaned enamel surface and irradiated at an energy output of 30 m...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900100510
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The goal of this study was to use an inexpensive macroscopic imaging system to monitor tumor progression in mouse models in real-time with minimal intervention. STUDY DESIGN/MATERIALS AND METHODS:Illumination is provided via a xenon arc lamp and a fiber optic probe which delivers white light o...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20409
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To further understand the precise process of the tumor cell degeneration after photodynamic therapy (PDT), laser hyperthermic therapy (LH), and combined treatments using an Nd:YAG laser. It is important to examine initial morphological alteration of tumor cells after these treatments. STUDY DE...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900160308
更新日期：1995-01-01 00:00:00
abstract：:This work presents measurements of time-resolved fluorescence microscopy of hematoporphyrin-derivative (HpD) in single cells of mice tissue (both tumor and normal cells), in HeLa Cells, and in solution. The measurements were performed using a pulsed-laser microfluorometer with high spatial and temporal resolution. In ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900020103
更新日期：1982-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The nonablative application of holmium:yttrium-aluminum-garnet (Ho:YAG) laser energy to the joint capsule of patients with glenohumeral instability has been found to shrink capsular tissue and to help stabilize the joint. The purpose of this study was to evaluate the effect of nonablative laser...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1997)20:2<164::aid-lsm7>3.
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Despite laser applications targetted toward tonsillar tissue, there has been no characterization of underlying optical and thermal events during laser irradiation of tonsillar tissue. STUDY DESIGN/MATERIALS AND METHODS:The optical properties of canine and human tonsils were determined at 805 n...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1055
更新日期：2001-01-01 00:00:00
abstract：:For our study of the effect of low energy laser irradiation (LELI) on living tissue we used HeNe laser on rats. The exponential absorption was reaffirmed in the living tissues overlying the sciatic nerve. An optimal range of energy between 3.5 and 7 J--associated with energy concentration of 4-10 J/cm2 delivered trans...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900060502
更新日期：1986-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Hypervascular skin lesions (HVSL) are treated with medical lasers characterized by a variety of parameters such as wavelength lambda, pulse duration t(p), and radiant exposure E that can be adjusted for different pathology and blood vessel size. Treatment parameters have been optimized assumin...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20154
更新日期：2005-04-01 00:00:00
abstract：:Current laser dentistry since our initial studies in 1964 is reviewed. Three areas are considered: routine dental office practice, tooth restoration, and oral surgery. For tooth restoration and oral surgery, CO2 and neodymium:YAG lasers are used and lasers are used in photodynamic therapy for oral cancer. Dental offic...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900060616
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:To investigate the effect of photodynamic therapy (PDT) on cell death in malignant tumor tissue, the frequency of terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL)-positive cells and the possible involvement of Fas and Fas ligand system were evaluated. STUDY DESIGN...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/1096-9101(2000)26:5<449::aid-lsm4>3.0.co;2
更新日期：2000-01-01 00:00:00
abstract：:Our experiments on transmitting high-power excimer laser pulses through optical fibers and our investigations on excimer laser ablation of hard tissue show the feasibility of using the excimer laser as an additional instrument in general and accident surgery involving minimal invasive surgery. By combining XeCl-excime...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900110612
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The current study (for which ethical approval was obtained) sought to assess the effect of low intensity monochromatic infrared therapy (LIMIRT) on experimentally induced delayed onset muscle soreness (DOMS). STUDY DESIGN/MATERIALS AND METHODS:Healthy volunteers were recruited (n = 24, 12M:12F...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1002/1096-9101(2001)28:1<33::AID-LSM1012>3.0.CO
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Autofluorescence (AF) emission is an intrinsic parameter that can provide real-time information on morpho-functional properties of biological tissue, being strictly related with their biochemical composition and structural organization. The diagnostic potentials of AF-based techniques have been...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20923
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Most women with early stage breast cancer have the option of breast conserving therapy, which involves a partial mastectomy for removal of the primary tumor, usually followed by radiotherapy. The presence of tumor at or near the margin is strongly correlated with the risk of local tumor recurre...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20865
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:A randomized clinical trial using the argon-green (514 nm) and the double-frequency Nd:YAG (532 nm) lasers was carried out on 42 eyes with proliferative diabetic retinopathy (PDR), with the aim of assessing the long-term effects of double-frequency Nd:YAG panretinal photocoagulation (PRP). MAT...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1002/(SICI)1096-9101(1996)19:2<173::AID-LSM8>3.
更新日期：1996-01-01 00:00:00
abstract：:To date, there are two fairly well-established alternatives for laser-induced shock-wave lithotripsy in clinical practice. The Q-switched Nd:YAG laser is distinguished by the high-stone selectivity of its coupler systems. The necessity of a coupler system and its fairly small conversion rate of light energy into mecha...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900080405
更新日期：1988-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Intense pulsed light (IPL) is regarded as the gold standard of nonablative photo-rejuvenation. Yet there is still a need to observe its efficacy and safety on dark skin using a split-face module. STUDY DESIGN/MATERIALS AND METHODS:Twenty-four Chinese women with photoaging were enrolled in thi...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章,随机对照试验
doi：10.1002/lsm.20889
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In recent years, selective photothermolysis (PT) based on broadband light and assisted by skin vacuum (Photopneumatic Technology or PPx, by Aesthera) was introduced into the aesthetic market for epilation (hair removal) procedures. The present study aims to: (a) determine the overall effect of ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20743
更新日期：2009-02-01 00:00:00
