Abstract:
BACKGROUND AND OBJECTIVES:This preliminary report describes a new laser-assisted treatment option for the emerging complication of bisphosphonate related osteonecrosis (BON) of the jaw. MATERIALS AND METHODS:In eight tumour patients (three women, five men) ten bony lesions in the maxilla and mandible in the course of intravenous bisphosphonate therapy were treated with a variable square pulsed (VSP) Er:YAG laser. For the treatment, the Er:YAG laser was applied with a pulse energy of 1,000 mJ, a pulse duration of 300 microseconds, and a frequency of 12 Hz (energy density 157 J/cm(2)). The spot size was 0.9 mm and the handpiece was kept at a distance of about 10 mm from the bone surface. The diseased bone was ablated exclusively with the Er:YAG laser by subsequently sweeping the bone surface in a well directed scanning mode. RESULTS:The surgical procedure and postoperative wound healing were without any complications and a complete soft tissue recovering was achieved within 4 weeks. During follow-up examinations over 12 months soft tissue conditions were stable. The pulsed laser ablation caused a characteristic microstructured and craggy bone surface without a condensation or a smear layer on the laser rims. CONCLUSION:The bone ablation technique using a VSP Er:YAG laser yielded promising clinical results without impairment of wound healing. A further analyse of the chemical, physical and pharmacological aspects of laser assisted treatment of BON lesions is necessary to get a safe and reliable treatment protocol for bisphosphonate-related osteonecrosis of the jaw.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Stübinger S,Dissmann JP,Pinho NC,Saldamli B,Seitz O,Sader Rdoi
10.1002/lsm.20730subject
Has Abstractpub_date
2009-01-01 00:00:00pages
26-30issue
1eissn
0196-8092issn
1096-9101journal_volume
41pub_type
临床试验,杂志文章abstract::The potential problem of rethrombosis after laser recanalization was studied in 16 thrombus-occluded canine femoral arteries. Balloon de-endothelialization and thrombin-human blood injection produced adherent, completely occlusive thrombi 4.13 +/- 1.54 cm in length; laser exposure of the thrombi occurred at 18.35 +/- ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900050311
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abstract:BACKGROUND AND OBJECTIVES:Recently, there have been several attempts to apply the laser therapy to hypertrophic scars (HTS). In particular, the fractional laser is in the spotlight for its usefulness in rapid wound healing and dermal remodeling. However, most previous studies have focused on the ablative fractional las...
journal_title:Lasers in surgery and medicine
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doi:10.1002/lsm.23334
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abstract:BACKGROUND AND OBJECTIVES:Intralipid (IP) is a scatterer extensively used in the building of phantoms for Biomedical Optics measurements. Recently, deviations from the linearity have been shown for the concentration scaling law of the scattering coefficient of IP water solutions at visible wavelengths. In this work thi...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20157
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abstract:OBJECTIVES:Cryolipolysis of the arms has been demonstrated to be an effective treatment for non-invasive reduction of subcutaneous fat. This study evaluated the safety and efficacy of the concurrent use of a new commercially-available small applicator in conjunction with an existing medium sized applicator for the cust...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22811
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abstract::A technique for partial nephrectomy using a combination of an Ultrasonic Surgical Aspirator and a neodymium:YAG laser provided better hemostasis and decreased total operative time compared to standard methods. Delayed hemorrhage was not seen, and thermal damage to the remaining renal parenchyma was minimal. ...
journal_title:Lasers in surgery and medicine
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abstract:BACKGROUND AND OBJECTIVES:Kenalog application onto surgical wounds has been used to control dynamic pain following Laser-Assisted-Uvulo-Palatoplasty (LAUP) with good results in our department. When the effect was sub-optimal, insufficient ointment over the superior-lateral corner of wounds were always noted. Fulfilling...
journal_title:Lasers in surgery and medicine
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,多中心研究,随机对照试验
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abstract:BACKGROUND AND OBJECTIVES:In this study, methylene blue-mediated photodynamic therapy (MB-PDT) was used as a possible alternative method for the treatment of oral lichen planus (OLP). STUDY DESIGN/MATERIALS AND METHODS:Thirteen patients with 26 OLP lesions were enrolled in this study. Patients were instructed to gargl...
journal_title:Lasers in surgery and medicine
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abstract::A low-energy Nd:YAG laser was used to irradiate extracted human teeth coated with a black energy-absorbent laser initiator in a study to determine the extent of the morphologic changes produced in the enamel surface. The laser initiator was applied to a cleaned enamel surface and irradiated at an energy output of 30 m...
journal_title:Lasers in surgery and medicine
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:2008-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Laser-assisted tissue repair is often accompanied by a high dehiscence rate, which may be due to alterations in suture material after laser exposure. The goal of this study was to investigate the effect of CO2 laser irradiation on the tensile strength of microsurgical suture material. STUDY DE...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.22050
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abstract:BACKGROUND AND OBJECTIVE:Some oral bacteria are susceptible to killing by red light after their sensitization with toluidine blue O (TBO). The photochemotherapy of periodontal disease in vivo would require a therapeutic window where bacteria could be killed without adjacent normal tissue damage. STUDY DESIGN/MATERIALS...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVE:The reactive oxygen mechanisms associated with cell damage after photodynamic therapy (PDT) may be exploited to enhance tumor destruction. Pharmacological reduction of glutathione (GSH), an inhibitor of reactive oxygen species, can be induced by administration of buthionine sulfoximine (BSO). ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/(sici)1096-9101(1998)23:3<161::aid-lsm5>3.
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Nanotechnology may increase the speed of penetration into the skin. This study evaluated the efficacy, safety, and pharmacokinetics of a novel topical anesthetic nanocapsule formulation (2 g) containing 2.5% lidocaine and 2.5% prilocaine (nanorap-test formulation) compared to placebo (control ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
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abstract::A laser endoscope was devised using optic fibers in order to provide a means of visualization and removal of atheromatous plaques from arteries in cadavers and experimental animals. Atheromatous plaques were satisfactorily lased off in a few seconds, although contraction of lased vessels was observed. A self-focusing ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
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doi:10.1002/(sici)1096-9101(1997)21:2<134::aid-lsm4>3.
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVE:Lines of radiofrequency ablation for cure of atrial fibrillation are broad, and the consequent loss of atrial mass may impair atrial function and contribute to the risk of stroke. We studied whether Nd:YAG laser could produce deep but narrower lesions. STUDY DESIGN/MATERIALS AND METHODS:Laser ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1065
更新日期:2001-01-01 00:00:00
abstract::Laser physiology has shown that while wound healing is generally excellent after laser impaction, it nevertheless is delayed. It is thought that this factor may be important in the treatment of hypertrophic and keloid scars. These scars have been treated in a variety of ways with the laser, and the results, which have...
journal_title:Lasers in surgery and medicine
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journal_title:Lasers in surgery and medicine
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
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更新日期:2016-12-01 00:00:00
abstract::The acute or emergency treatment of traumatic tattoos has been based on the principles of immediate and thorough removal of all particles. The delayed treatment of traumatic tattoos has classically been with overgrafting or dermabrasion. We developed an animal model for traumatic tattoos. Two levels of wounds were mad...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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