Abstract:
BACKGROUND AND OBJECTIVES:Intense pulsed light (IPL) is regarded as the gold standard of nonablative photo-rejuvenation. Yet there is still a need to observe its efficacy and safety on dark skin using a split-face module. STUDY DESIGN/MATERIALS AND METHODS:Twenty-four Chinese women with photoaging were enrolled in this study. Patients were randomized to receive four IPL treatments at 3- to 4-week intervals on one side of face, with the other side spared as control. Changes of photoaging were evaluated using a global evaluation, an overall self-assessment, a Mexameter and a Corneometer. Skin biopsies were taken after four sessions of treatment on one side of face. The melanocyte density and the contents of melanin, collagen fibers, and elastic fibers were stained and used to evaluate the improvement on dyschromia and other signs of photoaging. RESULTS:The global scores of photoaging on treated side decreased significantly from 3.02 to 1.22, while it remained unchanged on the untreated side. Twenty-one of 24 patients (87.5%) rated their improvement as excellent or good. The difference on the values of melanin index and erythema index on treated side were significantly larger than those on untreated side after the 1st session, the 4th session and at 3-month follow-up (P<0.05). The melanin contents were significantly decreased and the collagen fibers were obviously increased only on treated side (P<0.05). Adverse effects of treated side were limited to mild pain and transient erythema. CONCLUSION:Using this split-face module, IPL treatment is proved both clinically and histologically to be effective in treating photoaging skin in Chinese population. Adverse effects were minimal and acceptable.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Li YH,Wu Y,Chen JZ,Zhu X,Xu YY,Chen J,Dong GH,Gao XH,Chen HDdoi
10.1002/lsm.20889subject
Has Abstractpub_date
2010-02-01 00:00:00pages
185-91issue
2eissn
0196-8092issn
1096-9101journal_volume
42pub_type
杂志文章,随机对照试验abstract::Rapidly expanding laser technology has created a void in surgical instrumentation when the carbon dioxide laser is applied to intra-abdominal microlaser fertility-promoting procedures. By using proper instruments, the laser microsurgeon will be able to enhance his surgical technique as well as reduce his frustrations....
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900020307
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to evaluate the efficacy and safety of the intense pulsed light source (IPL) and the Nd:YAG laser in the treatment of facial rhytids. Both systems can be used in a non-ablative manner and cause a dermal wound. This is thought to stimulate the production of new collagen...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
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abstract:BACKGROUND AND OBJECTIVES:Energy-based treatments have been found to be a promising treatment modality for improving stress urinary incontinence (SUI) symptoms. This prospective two-center study was designed to evaluate the efficacy of fractional-pixel CO2 laser for the treatment of SUI. STUDY DESIGN/MATERIALS AND MET...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVE:The clinical application of laser-assisted vascular anastomosis is afflicted by unreliable and low bonding strengths as well as tedious handling during microvascular surgery. The challenge to be met arises from the flow-off of the chromophore during soldering that changes the absorption and sta...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVE:To evaluate the effects on disruption of hair growth of the non-coherent filtered flashlamp intense pulsed light (IPL) source. MATERIALS AND METHODS:Twenty-eight sites on 23 patients with Fitzpatrick type I-III were enrolled using a single treatment IPL followed for three months post-treatment...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章,随机对照试验
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abstract:BACKGROUND AND OBJECTIVE:Both photodynamic (PDT) and photothermal (PTT) therapy have proven to be effective treatment strategies for cancer, but the approach of combining them into a single treatment modality may offer better treatment efficacy. We compare the treatment efficacy of such combined treatment with the indi...
journal_title:Lasers in surgery and medicine
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abstract:BACKGROUND:The treatment of acne scars with fractional CO(2) lasers is gaining increasing impact, but has so far not been compared side-by-side to untreated control skin. OBJECTIVE:In a randomized controlled study to examine efficacy and adverse effects of fractional CO(2) laser resurfacing for atrophic acne scars com...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章,随机对照试验
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更新日期:2012-08-01 00:00:00
abstract::Ablative lasers (CO2 and Er:YAG) provide the greatest improvement in photoaging, but significant adverse effects limit their use. Nonablative lasers have reduced adverse effects, but limited efficacy. Fractional photothermolysis (FP) produces arrays of microscopic thermal wounds called microscopic treatment zones (MTZ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Although several studies on laser-assisted hair removal have been published, data on long-term follow-up are few. The present study investigated the long-term efficacy and safety of normal-mode ruby laser pulses on hair removal. STUDY DESIGN/MATERIALS AND METHODS:The normal-mode ruby laser (Ep...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVE:A port wine stain (PWS) is a type of capillary vascular malformation composed of malformed, dilated blood vessels within the papillary and reticular dermis. Currently, pulsed dye laser (PDL) is considered the therapeutic gold standard, although greater than 90% of lesions may be refractory to t...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVE:Soft tissue sarcomas (STS) are a rare and heterogeneous group of malignant tumors that are often treated through surgical resection. Current intraoperative margin assessment methods are limited and highlight the need for an improved approach with respect to time and specificity. Here we investi...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/(sici)1096-9101(1999)24:3<194::aid-lsm4>3.
更新日期:1999-01-01 00:00:00
abstract::Thirty-six deep hepatic lesions of localized photocoagulation were induced in 11 pigs by means of a neodymium-YAG laser. Laser applications of 80 W/10 sec (10.190 W/cm2) were transmitted through a handpiece coupled to a water-cooling circulation system to protect the quartz fiber and positioned through an echo-guided ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900080509
更新日期:1988-01-01 00:00:00
abstract::The photocoagulating properties of the water-jet-cooled Nd:YAG laser (1,064 nm) have been studied in a rat tumor model. A colon carcinoma CC531 was implanted in the liver; 20 days after inoculation, laser therapy was performed with 600 J, 850 J, 1,200 J, 1,700 J, or 2,400 J at a power setting of either 10 or 20 W. Liv...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.1900110510
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Transient optical nerve stimulation is a promising new non-contact, spatially precise, artifact-free neural excitation technique useful in research and clinical settings. This study evaluates safety of this pulsed infrared laser technique by histopathologic examination of stimulated peripheral ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/lsm.20522
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Acne scarring is a common complication of acne but no effective single treatment modality has been developed. To compare the efficacy of 1,550 nm Er:Glass fractional laser and chemical reconstruction of skin scar (CROSS) method in the treatment of acne scars. STUDY DESIGN/MATERIALS AND METHODS...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
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abstract:BACKGROUND AND OBJECTIVE:The reactive oxygen mechanisms associated with cell damage after photodynamic therapy (PDT) may be exploited to enhance tumor destruction. Pharmacological reduction of glutathione (GSH), an inhibitor of reactive oxygen species, can be induced by administration of buthionine sulfoximine (BSO). ...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
doi:10.1002/(sici)1096-9101(1998)23:3<161::aid-lsm5>3.
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:A randomized clinical trial using the argon-green (514 nm) and the double-frequency Nd:YAG (532 nm) lasers was carried out on 42 eyes with proliferative diabetic retinopathy (PDR), with the aim of assessing the long-term effects of double-frequency Nd:YAG panretinal photocoagulation (PRP). MAT...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-01-01 00:00:00
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:2011-01-01 00:00:00
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:2005-06-01 00:00:00
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journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVES:During transmyocardial laser revascularization (TMLR), multiple microembolic signals (MES) can be detected in cerebral arteries. We sought to characterize composition and clinical relevance of these MES and to evaluate strategies to reduce cerebral microembolization during TMLR. STUDY DESIGN/...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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abstract:BACKGROUND AND OBJECTIVE:To further understand the precise process of the tumor cell degeneration after photodynamic therapy (PDT), laser hyperthermic therapy (LH), and combined treatments using an Nd:YAG laser. It is important to examine initial morphological alteration of tumor cells after these treatments. STUDY DE...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
abstract::Laser physiology has shown that while wound healing is generally excellent after laser impaction, it nevertheless is delayed. It is thought that this factor may be important in the treatment of hypertrophic and keloid scars. These scars have been treated in a variety of ways with the laser, and the results, which have...
journal_title:Lasers in surgery and medicine
pub_type: 杂志文章
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更新日期:1984-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The recently introduced Er:YAG laser seems to be a promising alternative in periodontal treatment due to its thermo-mechanical ablation mechanism. The present study attempted to compare the effects of an Er:YAG laser on periodontally involved root surfaces at different power settings in vivo an...
journal_title:Lasers in surgery and medicine
pub_type: 临床试验,杂志文章
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更新日期:2001-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:An ideal treatment for pilonidal disease should feature a low recurrence rate, minimal incision, and rapid return to daily activities. We compared the outcomes of the well-defined Karydakis technique (KT) and a combination of pit excision (PE) and sinus tract ablation using 1,470-nm diode lase...
journal_title:Lasers in surgery and medicine
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更新日期:2020-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Although topical corticosteroids are still the first-line option for vitiligo, its efficacy is still unsatisfactory for stable vitiligo. A few studies have focused on laser-assisted drug delivery (LADD) but were limited by their sample deficiency and analyses of the influencing factors. To det...
journal_title:Lasers in surgery and medicine
pub_type:
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