Laser soldering of rat skin, using fiberoptic temperature controlled system.

Abstract:

BACKGROUND AND OBJECTIVE:Laser soldering of tissues is based on the application of a biological solder on the approximated edges of a cut. Our goal was to use laser soldering for sealing cuts in skin under temperature feedback control and compare the results with ones obtained using standard sutures. STUDY DESIGN/MATERIALS AND METHODS:Albumin solder was applied onto the approximated edges of cuts created in rat skin. A fiberoptic system was used to deliver the radiation of a CO(2) laser, to heat a spot near the cut edges, and to control the temperature. Laser soldering was carried out, spot by spot, where the temperature at each spot was kept at 65-70 degrees C for 10 sec. RESULTS:The tensile strength of laser-soldered cuts was measured after 3-28 days postoperatively and was found comparable to that of sutured cuts. Histopathological studies showed no thermal damage and less inflammatory reaction than that caused by standard sutures (P = 0.04). CONCLUSIONS:Temperature controlled laser soldering of cuts in rat skin gave strong bonding. The cosmetic and histological results were very good, in comparison to those of standard sutures.

journal_name

Lasers Surg Med

authors

Simhon D,Ravid A,Halpern M,Cilesiz I,Brosh T,Kariv N,Leviav A,Katzir A

doi

10.1002/lsm.1118

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

265-73

issue

3

eissn

0196-8092

issn

1096-9101

pii

10.1002/lsm.1118

journal_volume

29

pub_type

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