Chlorophyllin-M: A new substance for photodynamic therapy in the retina and choroid.

abstract：INTRODUCTION:Leg telangiectasias have been reported to have been treated with a variety of lasers. This study was designed to measure response to treatment of leg telangiectasias with a unique coupled 585 nm and 1064 nm pulse. METHODS:Sixty female patients (24-62 y.o., skin types II-IV) with leg vein varicosities were...

journal_title：Lasers in surgery and medicine

authors： Trelles MA,Weiss R,Moreno-Moragas J,Romero C,Vélez M,Alvarez X

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Basal cell carcinoma (BCC) is an indolent form of skin cancer that is rarely life threatening, but can cause significant cosmetic and functional morbidity. Surgical treatments often result in disfiguring scars, while topical therapies frequently result in recurrence. The need for a more effecti...

journal_title：Lasers in surgery and medicine

authors： Ortiz AE,Anderson RR,DiGiorgio C,Jiang SIB,Shafiq F,Avram MM

更新日期：2018-02-13 00:00:00

abstract：:Thirty-six deep hepatic lesions of localized photocoagulation were induced in 11 pigs by means of a neodymium-YAG laser. Laser applications of 80 W/10 sec (10.190 W/cm2) were transmitted through a handpiece coupled to a water-cooling circulation system to protect the quartz fiber and positioned through an echo-guided ...

journal_title：Lasers in surgery and medicine

authors： Godlewski G,Rouy S,Pignodel C,Ould-Said H,Eledjam JJ,Bourgeois JM,Sambuc P

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Although topical corticosteroids are still the first-line option for vitiligo, its efficacy is still unsatisfactory for stable vitiligo. A few studies have focused on laser-assisted drug delivery (LADD) but were limited by their sample deficiency and analyses of the influencing factors. To det...

journal_title：Lasers in surgery and medicine

authors： Huang C,Li P,Wang B,Deng Y,Li J,Mao M,Jian D

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of the in vitro study was to examine the clinical efficacy of semiconductor laser periodontal pocket irradiation as an adjunct to conventional scaling and root planing. MATERIALS AND METHODS:Twenty-two healthy patients with a need of periodontal treatment (15 women, 7 men, mean age 45...

journal_title：Lasers in surgery and medicine

authors： Kreisler M,Al Haj H,d'Hoedt B

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Laser light of various wavelengths is being used for surgical procedures in otolaryngology. Apart from well-known fiber guided laser systems such as Nd:YAG- and Ho:YAG-lasers, newly developed diode-laser systems of different wavelengths have recently become popular in surgery. In order to comp...

journal_title：Lasers in surgery and medicine

authors： Janda P,Sroka R,Mundweil B,Betz CS,Baumgartner R,Leunig A

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The aim was to evaluate the influence of Er,Cr:YSGG laser irradiation associated with different final irrigation protocols on the bond strength of epoxy resin-based root canal sealer to root dentin, on the dentin/filling material interface and in the temperature variation during irradiation. METHODOLOGY:Nine...

journal_title：Lasers in surgery and medicine

authors： Franceschini KA,Silva-Sousa YT,Lopes FC,Pereira RD,Palma-Dibb RG,de Sousa-Neto MD

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Lasers can be used to modify the chemical composition of dental enamel to increase the bond strength to restorative materials and to render the mineral phase more resistant to acid dissolution. Previous studies have suggested a synergistic relationship between CO(2) laser irradiation and fluor...

journal_title：Lasers in surgery and medicine

authors： Wheeler CR,Fried D,Featherstone JD,Watanabe LG,Le CQ

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) offers the potential for enhanced treatment of nonmelanoma skin cancer (NMSC) with minimal scarring. Yet, PDT has not achieved consistent long term effectiveness to gain widespread clinical acceptance for treatment of skin cancer. Therapeutic response varies between practitioners, ...

journal_title：Lasers in surgery and medicine

authors： Saager RB,Cuccia DJ,Saggese S,Kelly KM,Durkin AJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:As a potential therapy for malignant glioma, we tested the phthalocyanine photosensitizer Pc 4 for: (1) rapid clearance from the vasculature, (2) specificity for glioma, and (3) tumoricidal photosensitizing capability. STUDY DESIGN/MATERIALS AND METHODS:Parenchymal injection of U87 cells into...

journal_title：Lasers in surgery and medicine

authors： George JE 3rd,Ahmad Y,Varghai D,Li X,Berlin J,Jackowe D,Jungermann M,Wolfe MS,Lilge L,Totonchi A,Morris RL,Peterson A,Lust WD,Kenney ME,Hoppel CL,Sun J,Oleinick NL,Dean D

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Endoscopic examination followed by tissue biopsy is the gold standard in the evaluation of lesions of the upper aerodigestive tract. However, it can be difficult to distinguish between healthy mucosa, dysplasia, and invasive carcinoma. Optical coherence tomography (OCT) is a non-invasive technique which acqui...

journal_title：Lasers in surgery and medicine

authors： Englhard AS,Betz T,Volgger V,Lankenau E,Ledderose GJ,Stepp H,Homann C,Betz CS

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) using topical aminolevulinic acid (ALA) depends on local drug uptake, metabolism to porphyrins, and depth of light penetration using different wavelengths. Topical ALA-PDT has limited depth of drug penetration. We studied induced porphyrin distribution and PDT after intradermal ALA...

journal_title：Lasers in surgery and medicine

authors： Sakamoto FH,Doukas AG,Farinelli WA,Tannous Z,Su Y,Smith NA,Zurakowski D,Anderson RR

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Recent studies have sought to utilize diode laser "micropulsing" in order to preserve therapeutic efficacy of retinal photocoagulation while minimizing pain and subjacent tissue injury. A model for the transient thermal tissue response to continuous and micropulsed diode laser output is present...

journal_title：Lasers in surgery and medicine

authors： Berger JW

更新日期：1997-01-01 00:00:00

abstract：:Progress in the young field of laser recanalization of occluded arteries and applications in cardiovascular disease to which many investigators have contributed is briefly summarized. Specific problems remaining to be solved are set forth. In conclusion, the author makes a cautious prediction of success for the percut...

journal_title：Lasers in surgery and medicine

authors： Choy DS

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Many studies have investigated the application of micro-insulated needles with radio frequency (RF) to treat acne in humans; however, the use of a micro-insulated needle RF applicator has not yet been studied in an animal model. The purpose of this study was to evaluate the effectiveness of a ...

journal_title：Lasers in surgery and medicine

authors： Kwon TR,Choi EJ,Oh CT,Bak DH,Im SI,Ko EJ,Hong HK,Choi YS,Seok J,Choi SY,Ahn GY,Kim BJ

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Low level laser irradiation (LLLI) is used to promote wound healing. Molecularly it is known to stimulate mitochondrial membrane potential (MMP), cytokine secretion, and cell proliferation. This study was designed to determine the influence of LLLI on the kinetics of MMP stimulation and decay,...

journal_title：Lasers in surgery and medicine

authors： Gavish L,Asher Y,Becker Y,Kleinman Y

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The main factors in photodynamic therapy (PDT) are: photosensitizer retention, photon absorption, and oxygen supply. Each factor has its unique set of problems that poses limitation to the treatment. Both light delivery and oxygen supply are significant bottlenecks in PDT. Vascular closure duri...

journal_title：Lasers in surgery and medicine

authors： Yang L,Wei Y,Xing D,Chen Q

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To determine the true efficacy of the 308-nm excimer laser for the treatment of vitiligo, while taking into account confounding factors such as anatomic site of treatment, age, sex, skin type, MED, and duration of evolution of the vitiligo. STUDY DESIGN/MATERIALS AND METHODS:Thirty-five patie...

journal_title：Lasers in surgery and medicine

authors： Ostovari N,Passeron T,Zakaria W,Fontas E,Larouy JC,Blot JF,Lacour JP,Ortonne JP

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Varied physical and chemical characteristic of root canal sealers and different irrigant agitation systems can influence the depth of penetration. The aim of this in vitro study was to use a laser scanning confocal microscope in order to assess the dentinal tubules penetration of various sealer...

journal_title：Lasers in surgery and medicine

authors： Akcay M,Arslan H,Durmus N,Mese M,Capar ID

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In recent years, clinical low-intensity laser therapy practice has used pulsed radiation, mainly from semiconductor lasers. Experimental works devoted to the study of relationships between biological and clinical effects and parameters of pulsed radiation are practically absent. STUDY DESIGN/M...

journal_title：Lasers in surgery and medicine

authors： Karu TI,Pyatibrat LV,Ryabykh TP

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The risk of adverse skin effects following light-based hair removal is greater in pigmented skin based on the theory of selective photothermolysis. Thus sunlight-induced pigment i.e., facultative pigmentation, increases the risk of adverse skin effects, perhaps disproportionately. The aim of t...

journal_title：Lasers in surgery and medicine

authors： Thaysen-Petersen D,Lin JY,Nash J,Beerwerth F,Wulf HC,Philipsen PA,Haedersdal M

更新日期：2014-02-01 00:00:00

abstract：:The in vivo biological activity of uroporphyrin I has been studied by determining the amount of necrosis produced in murine tumors exposed to various total doses of light at 615 nm. Similarly, the in vitro photosensitizing activity of uroporphyrin I was examined by measuring the percentage of cells killed in a cell cu...

journal_title：Lasers in surgery and medicine

authors： Nelson JS,Sun CH,Berns MW

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The use of pulsed dye laser (PDL) and fractional CO2 (FX CO2 ) laser therapy to treat and/or prevent scarring following burn injury is becoming more widespread with a number of studies reporting reduction in scar erythema and pruritus following treatment with lasers. While the majority of studi...

journal_title：Lasers in surgery and medicine

authors： Bailey JK,Blackstone BN,DeBruler DM,Kim JY,Baumann ME,McFarland KL,Imeokparia FO,Supp DM,Powell HM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:We sought to investigate risk factors for recurrence of vaginal intraepithelial neoplasia (VAIN) in the vaginal vault after laser vaporization. MATERIALS AND METHODS:Among 162 patients treated with laser vaporization in the vaginal vault after hysterectomy between March 1998 and August 2007, the clinical da...

journal_title：Lasers in surgery and medicine

authors： Kim HS,Park NH,Park IA,Park JH,Chung HH,Kim JW,Song YS,Kang SB

更新日期：2009-03-01 00:00:00

abstract：:A 1-J/cm2 dose of single laser-irradiation applied on primary human embryo fibroblast culture was not followed either by functional or micromorphological alterations of cell surfaces. This dose, however, applied four times with 24-hour intervals changed the functional conditions as well as surface charges of cell memb...

journal_title：Lasers in surgery and medicine

authors： Kubasova T,Kovács L,Somosy Z,Unk P,Kókai A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Fiber-assisted laser surgery has been employed as a minimally invasive method in various medical fields. In spite of multiple sweeping on tissue during laser treatments, the rate of tissue removal gradually decreases and eventually leads to longer irradiation times as well as deeper thermal inj...

journal_title：Lasers in surgery and medicine

authors： Oh J,Nam SY,Lee YW,Kang HW

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this clinical study was to evaluate the safety of local delivery of a photosensitizer followed by photodynamic therapy (PDT), to determine its effectiveness in reducing in-stent restenosis. STUDY DESIGN/PATIENTS AND METHODS:Porfimer sodium was administered via a local delivery cath...

journal_title：Lasers in surgery and medicine

authors： Usui M,Miyagi M,Fukasawa S,Hara T,Ueyama N,Nakajima H,Takata R,Sasame A,Tamura K,Naitou Y,Yamashina A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is an increasing interest in treating vascular lesions with a long-pulse Alexandrite laser. However, it is difficult to search information in the literature about infantile hemangiomas (IH) treated with long-pulse Alexandrite laser. This article aims to determine whether 755 nm long-pulse...

journal_title：Lasers in surgery and medicine

authors： Su W,Ke Y,Xue J

更新日期：2014-03-01 00:00:00

abstract：:Our experiments on transmitting high-power excimer laser pulses through optical fibers and our investigations on excimer laser ablation of hard tissue show the feasibility of using the excimer laser as an additional instrument in general and accident surgery involving minimal invasive surgery. By combining XeCl-excime...

journal_title：Lasers in surgery and medicine

authors： Dressel M,Jahn R,Neu W,Jungbluth KH

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The pulsed holmium laser is a promising tool for tissue ablation but possesses some limitations. For example, it is capable of producing significant mechanical damage in certain tissues in the form of fissures and fractures. Because longer pulse durations should reduce mechanical damage, this s...

journal_title：Lasers in surgery and medicine

authors： Domankevitz Y,McMillan K,Nishioka NS

更新日期：1996-01-01 00:00:00