Abstract：
BACKGROUND AND OBJECTIVES:To determine the true efficacy of the 308-nm excimer laser for the treatment of vitiligo, while taking into account confounding factors such as anatomic site of treatment, age, sex, skin type, MED, and duration of evolution of the vitiligo. STUDY DESIGN/MATERIALS AND METHODS:Thirty-five patients with vitiligo were included. Each lesion was treated twice a week by the 308-nm excimer laser for a maximum of 24 sessions. Efficacy was blindly evaluated by two independent physicians. RESULTS:Repigmentation was noted in 46 plaques/52 (88.5%). Repigmentation rate (75%) was obtained in 14 (26.9%). In "UV sensitive" areas (face, neck, trunk), 8/14 lesions (57.1%) had a repigmentation rate, 75% versus 6/38 (15.8%) in "UV resistant" areas (bony prominences and extremities) (P = 0.031). No relationship could be established between response to the treatment and the following variables: age, sex, skin type, MED, and duration of evolution of the vitiligo (respectively, P = 1, 0.666, 0.566, 0.628, 0.521). CONCLUSIONS:An aesthetically reasonable result is achieved essentially in "UV sensitive" areas, thus appearing to be the appropriate places of choice for this treatment.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Ostovari N,Passeron T,Zakaria W,Fontas E,Larouy JC,Blot JF,Lacour JP,Ortonne JPdoi
10.1002/lsm.20057subject
Has Abstractpub_date
2004-01-01 00:00:00pages
152-6issue
2eissn
0196-8092issn
1096-9101journal_volume
35pub_type
临床试验,杂志文章abstract：BACKGROUND AND OBJECTIVE:The current study (for which ethical approval was obtained) sought to assess the effect of low intensity monochromatic infrared therapy (LIMIRT) on experimentally induced delayed onset muscle soreness (DOMS). STUDY DESIGN/MATERIALS AND METHODS:Healthy volunteers were recruited (n = 24, 12M:12F...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1002/1096-9101(2001)28:1<33::AID-LSM1012>3.0.CO
更新日期：2001-01-01 00:00:00
abstract：:Previous reports of effects of CO2 laser energy on human fibrocartilage suggest thermal injury extends to a depth of approximately 70 microns from the target surface with power settings of 35 W and exposure times of 0.5 seconds. The present study was undertaken to look for more subtle evidence of thermal alteration of...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900070209
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Herein an overview is provided of the causes, consequences, and significance of photodynamic therapy (PDT)-mediated effects on tumor oxygenation and blood flow during illumination. STUDY DESIGN/MATERIALS AND METHODS:Techniques particularly valuable to this research have included tissue oxygen ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章,评审
doi：10.1002/lsm.20355
更新日期：2006-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:To test whether autofluorescence spectroscopy can be used for the diagnosis of oral neoplasia in a high-risk population, we characterized the in vivo autofluorescence spectra from oral submucous fibrosis (OSF) lesions and oral premalignant and malignant lesions in both OSF and non-OSF patients...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.10180
更新日期：2003-01-01 00:00:00
abstract：:Low power laser irradiation has been reported to cause biological effects due to the photochemical and/or photophysical action of the radiation. This study determined quantitatively if transcutaneous low power laser irradiation can affect the regeneration of the rat facial nerve. The facial nerve was crushed unilatera...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900130113
更新日期：1993-01-01 00:00:00
abstract：:A study was conducted to compare the compressive strength, diametral tensile strength, transverse flexural strength, and flexural modulus of a microfilled and a small particle composite resin restorative material following argon laser and conventional visible light polymerization techniques. All physical properties ex...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900090613
更新日期：1989-01-01 00:00:00
abstract：:The effects of picosecond laser-induced optical breakdown on tissue were investigated using high-intensity 40 ps Nd:YAG laser pulses at 1.06 microns. Tissue damage was evaluated using the corneal endothelium in vitro as a model system. Systematic studies were performed to determine the scaling of the tissue damage and...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章,评审
doi：10.1002/lsm.1900090302
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Laser soldering of tissues is based on the application of a biological solder on the approximated edges of a cut. Our goal was to use laser soldering for sealing cuts in skin under temperature feedback control and compare the results with ones obtained using standard sutures. STUDY DESIGN/MATE...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1118
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Hyperhidrosis is a condition that affects a large percentage of the population and has a significant impact on peoples' lives. This report presents a technical overview of a new noninvasive, microwave-based device for creating thermolysis of sweat glands. The fundamental principles of operatio...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.21142
更新日期：2012-01-01 00:00:00
abstract：:We report the first study of the application of excimer lasers in dentistry for the treatment of dental root canals. High-energy ultraviolet (UV) radiation emitted by an XeCl excimer laser (308 nm) and delivered through suitable optical fibers can be used to remove residual organic tissue from the canals. To this aim,...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900090407
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The risks of currently available invasive procedures in body contouring motivate a need for safer, non-invasive technologies for improving the appearance of body silhouette. A new device has been developed that uses focused therapeutic ultrasound to reduce adipose tissue non-invasively. The ai...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.20478
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Hereditary hemorrhagic telangiectasia (HHT) is a hereditary condition that is associated with arteriovenous malformations. A common site for these malformations is the nasal mucosa, which is associated with severe epistaxis and debilitation for affected patients. We evaluated the efficacy and ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.23289
更新日期：2020-06-23 00:00:00
abstract：BACKGROUND AND OBJECTIVES:In Holmium laser lithotripsy, usually, the surgeon is guided by a visible beam superimposing the infrared (IR) treatment radiation. It has been shown that a green aiming beam excites stone autofluorescence. This fluorescence signal can be used for calculi detection to check the correct fiber p...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.23154
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In endodontics, a major diagnostic challenge is the accurate assessment of pulp status. In this study, we designed and characterized a fiber-based laser speckle imaging system to study pulsatile blood flow in the tooth. STUDY DESIGN/MATERIALS AND METHODS:To take transilluminated laser speckle ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22370
更新日期：2015-08-01 00:00:00
abstract：:The time constant model, as an approximation to the bio-heat equation, was tested for non-ablating, deep penetrating (argon) laser beams in absorbing tissue phantoms (polyacrylamide) in air. Temperature responses were measured with a thermal camera, both during laser irradiation as well as after the laser beam was swi...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900130615
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:This study was conducted to clarify the morphologic characteristics and subsequent repair process of coagulation necrosis produced by pulsed CO(2) laser irradiation with relatively low fluence, and thereby to evaluate the clinical efficacy of this irradiation mode. STUDY DESIGN/MATERIALS AND ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20712
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Acne scarring is a common complication of acne but no effective single treatment modality has been developed. To compare the efficacy of 1,550 nm Er:Glass fractional laser and chemical reconstruction of skin scar (CROSS) method in the treatment of acne scars. STUDY DESIGN/MATERIALS AND METHODS...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.20796
更新日期：2009-10-01 00:00:00
abstract：:The distribution of light in laser-irradiated biological medium is computed using four different procedures. Values computed with Beer's law of attenuation, Kubelka-Munk theory, the diffusion approximation, and a seven-flux model are compared. The proper conditions for using each model are discussed. ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900060603
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:Low-level laser therapy (LLLT) is a noninvasive treatment for a wide-assortment of medical ailments. A recent application is for noninvasive body slimming. A Level 1 clinical study was completed and recorded a significant reduction in circumferential measurements across waist, hips, and thighs compared to pl...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.22007
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Repair of peripheral nerve injuries remains a major challenge in restorative medicine. Effective therapies that can be used in conjunction with surgical nerve repair to improve nerve regeneration and functional recovery are being actively investigated. It has been demonstrated by a number of pe...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22212
更新日期：2014-01-01 00:00:00
abstract：:We describe our experience and the problems we encountered organizing an autonomous surgical unit in which the equipment and organization enable three lasers to be used in may different applications in medicine and surgery. The three lasers--CO2, Nd:YAG, and argon--may now be used by all the departments concerned with...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900030102
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Laser-induced photo thermal damage has been combined with photodynamic therapy (PDT) using a systemic photosensitiser to treat vascular lesions. The efficacy of PDT using systemic 5-aminolaevulinic acid (5-ALA) as the photosensitiser and pulsed dye laser (PDL) as the light source in port wine ...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1002/lsm.20151
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Laser-assisted tissue repair is often accompanied by a high dehiscence rate, which may be due to alterations in suture material after laser exposure. The goal of this study was to investigate the effect of CO2 laser irradiation on the tensile strength of microsurgical suture material. STUDY DE...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1997)20:1<64::aid-lsm10>3.
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Verteporfin is a new photosensitizer with short-term skin photosensitivity. The objective of this preclinical study was to find the light dose that effectively ablates canine esophageal mucosa when delivered 30 minutes after Verteporfin injection. STUDY DESIGN/MATERIALS AND METHODS:Verteporfin...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.10014
更新日期：2002-01-01 00:00:00
abstract：:We used a Q-switched Nd:YAG laser with non-linear optical crystals to produce the 5th (213 nm) and the 4th (266 nm) harmonic frequencies. Using these two wavelengths, we ablated fresh porcine corneas and type I collagen synthetic epikeratoplasty lenticules. For the 213-nm ablation, radiant exposure was 1.3 J/cm2. The ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900110610
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Primary cutaneous amyloidosis (PCA) comprises three main forms: macular, lichen, and nodular amyloidosis. The current available treatments are quite disappointing. OBJECTIVES:Assess and compare the clinical and histological changes induced by different modes of Fractional CO2 laser in treatment of PCA. PAT...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章,随机对照试验
doi：10.1002/lsm.22361
更新日期：2015-07-01 00:00:00
abstract：:Intestinal welding by means of low-power laser has been reported as an efficient method for intestinal anastomosis. We designed an experimental model in rats to investigate collagen and DNA concentrations in CO2 laser-welded anastomoses as compared with those in sutured anastomoses on the 4th, 7th, and 10th postoperat...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900140106
更新日期：1994-01-01 00:00:00
abstract：:partial ciliary processes argon laser photocoagulation (PCLP) in the management of glaucoma has been the subject of a carefully conducted, prospective 5+-year clinical trial in 22 eyes of 20 patients. The mean intraocular pressure (IOP) +/- SD was significantly lower (15.5 +/- 3.6 mm Hg) than before the procedure (29....
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.1900010109
更新日期：1980-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Despite laser applications targetted toward tonsillar tissue, there has been no characterization of underlying optical and thermal events during laser irradiation of tonsillar tissue. STUDY DESIGN/MATERIALS AND METHODS:The optical properties of canine and human tonsils were determined at 805 n...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1055
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The reactive oxygen mechanisms associated with cell damage after photodynamic therapy (PDT) may be exploited to enhance tumor destruction. Pharmacological reduction of glutathione (GSH), an inhibitor of reactive oxygen species, can be induced by administration of buthionine sulfoximine (BSO). ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1998)23:3<161::aid-lsm5>3.
更新日期：1998-01-01 00:00:00
