Solid state ultraviolet laser (213 nm) ablation of the cornea and synthetic collagen lenticules.

Abstract:

:We used a Q-switched Nd:YAG laser with non-linear optical crystals to produce the 5th (213 nm) and the 4th (266 nm) harmonic frequencies. Using these two wavelengths, we ablated fresh porcine corneas and type I collagen synthetic epikeratoplasty lenticules. For the 213-nm ablation, radiant exposure was 1.3 J/cm2. The ablation rate was 0.23 micron per pulse for the epikeratoplasty lenticules. We examined all tissues with light microscopy, transmission electron microscopy, and scanning electron microscopy. Histology for the 213-nm ablation showed a clean ablation crater with minimal collagen lamellae disruption and a damage zone less than 1 micron. In comparison, the 266 nm radiation showed more charring at the edges with a damage zone approximately 25 microns deep with disruption of the stromal lamella. Our results show that this solid state UV laser is a potential alternative to the excimer laser for cornea surgery.

journal_name

Lasers Surg Med

authors

Gailitis RP,Ren QS,Thompson KP,Lin JT,Waring GO 3rd

doi

10.1002/lsm.1900110610

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

556-62

issue

6

eissn

0196-8092

issn

1096-9101

journal_volume

11

pub_type

杂志文章
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