Abstract：
BACKGROUND:Optical energy-based devices, including intense pulsed light (IPL) and potassium titanyl phosphate (KTP) lasers achieve reduction of pigmented and vascular lesions in a relatively similar number of treatments. This study aimed to evaluate the efficacy and safety of an IPL with a "KTP-like" filter emitting a wavelength of 525-585 nm for the treatment of solar lentigines on the hands and face. METHODS:This was a single center, prospective, open-label clinical trial including 16 healthy Caucasian subjects (15 females, mean age, 55 years; skin types II and III) with hand and facial solar lentigines. Subjects were treated with three IPL treatment sessions with a KTP-like filter conducted at monthly intervals. Follow-up evaluations were performed 1, 3, and 6 months after the last treatment session. Overall pigmentation improvement, pigmentation clearance per lesion, adverse events, and subject tolerability to treatment were evaluated. RESULTS:Significant improvements in facial and hand pigmentation were noted at all follow-up visits (P < 0.0001). One month after the last treatment session, good to excellent outcomes were noted in 74.6% of treated facial areas and 90% of treated hand regions. Although the effect of treatment gradually declined in both treatment regions over the 6-month follow-up period, over 60% of subjects demonstrated good to excellent results at the study end. Clinical effectiveness was further confirmed by the reduction in Melanin Index (MI) following each treatment as compared to baseline. Downtime and complications were minimal. CONCLUSIONS:IPL treatment with a KTP-like filter is a well-tolerated and effective method for reducing facial and hand pigmentation. Lasers Surg. Med. 51:500-508, 2019. © 2019 Wiley Periodicals, Inc.
journal_name
Lasers Surg Medjournal_title
Lasers in surgery and medicineauthors
Friedmann DP,Peterson JDdoi
10.1002/lsm.23056subject
Has Abstractpub_date
2019-08-01 00:00:00pages
500-508issue
6eissn
0196-8092issn
1096-9101journal_volume
51pub_type
临床试验,杂志文章abstract：BACKGROUND AND OBJECTIVES:The argon laser-assisted vascular anastomosis may solve the problems of conventional sutured anastomosis, such as vascular stenosis and arrest of growth owing to a foreign-body reaction to suture material. STUDY DESIGN/MATERIALS AND METHODS:Twelve argon laser-assisted vascular anastomoses, se...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900160105
更新日期：1995-01-01 00:00:00
abstract：:We report the first study of the application of excimer lasers in dentistry for the treatment of dental root canals. High-energy ultraviolet (UV) radiation emitted by an XeCl excimer laser (308 nm) and delivered through suitable optical fibers can be used to remove residual organic tissue from the canals. To this aim,...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900090407
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:We developed novel heat-conducting templates, and tested whether they could effectively remove damaging heat from the tissue during laser ablation. The reduction of lateral thermal damage during cutaneous incisional laser procedures should decrease the time in wound healing. In addition, we se...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.10022
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Despite laser applications targetted toward tonsillar tissue, there has been no characterization of underlying optical and thermal events during laser irradiation of tonsillar tissue. STUDY DESIGN/MATERIALS AND METHODS:The optical properties of canine and human tonsils were determined at 805 n...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1055
更新日期：2001-01-01 00:00:00
abstract：:A 63 year old male underwent 6,900 rads of external radiation for a squamous cell carcinoma of the left main bronchus. Recurrence of the tumor 8 months later was treated with 6,618 joules and patency of the left main bronchus was restored. Four months later, he developed complete atelectasis of the left lung requiring...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900120316
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:In order to improve selectivity of photodynamic therapy (PDT) to choroidal neovascularization (CNV) associated with age-related macular degeneration, a laser scanning technique was applied to perform focal laser irradiation to the retina, and the occlusion effects of a new device to the chorio...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.10056
更新日期：2002-01-01 00:00:00
abstract：:A low-energy Nd:YAG laser was used to irradiate extracted human teeth coated with a black energy-absorbent laser initiator in a study to determine the extent of the morphologic changes produced in the enamel surface. The laser initiator was applied to a cleaned enamel surface and irradiated at an energy output of 30 m...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900100510
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Lymphangioma circumscriptum (LC) is a rare, benign, vascular malformation of dilated superficial lymphatic channels. Treatment is typically undertaken for cosmetic reasons or complications such as fluid drainage, pain, and infection risk that can negatively impact quality of life. Management of LC remains ch...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22379
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Energy-based treatments have been found to be a promising treatment modality for improving stress urinary incontinence (SUI) symptoms. This prospective two-center study was designed to evaluate the efficacy of fractional-pixel CO2 laser for the treatment of SUI. STUDY DESIGN/MATERIALS AND MET...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.23319
更新日期：2020-09-08 00:00:00
abstract：:Intestinal welding by means of low-power laser has been reported as an efficient method for intestinal anastomosis. We designed an experimental model in rats to investigate collagen and DNA concentrations in CO2 laser-welded anastomoses as compared with those in sutured anastomoses on the 4th, 7th, and 10th postoperat...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900140106
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Understanding albumin solder denaturation is important for laser tissue soldering. Human (HSA), bovine (BSA), porcine (PSA), and canine (CSA) albumin both fatty acid containing (FAC) and fatty acid free (FAF) were evaluated by using differential scanning calorimetry (DSC). STUDY DESIGN/MATERIA...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/1096-9101(2000)27:5<465::AID-LSM1007>3.0.C
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:To produce controlled, spatially confined thermal effects in dermis. STUDY DESIGNS/MATERIALS AND METHODS:A 1 W, 1,500 nm fiber-coupled diode laser was focused with a high numerical aperture (NA) objective to achieve a tight optical focus within the upper dermis of skin held in contact with a ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20142
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The objective of this study was to quantitatively measure changes in the elastic moduli of rabbit nasal septal cartilage during laser heating. While the efficacy of laser cartilage reshaping has been established for use in nasal surgery, few studies have investigated the temperature-dependent ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.10176
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Optical coherence tomography (OCT) provides ultrahigh-resolution imaging of tissues within a depth of a few millimeters, whereas ultrasonography provides good imaging further below the surface. We aimed to develop a minimally invasive rabbit model of VX2 laryngeal cancer, suitable for these two...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22409
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:Owing to skin aging and the growing demand for skin rejuvenation, minimal invasive aesthetic treatments such as laser procedures are increasingly coming into focus. However, until now, little has been known about the objective effects of these procedures with respect to skin microcirculation or changes in ski...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.22710
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:This laboratory animal study is a comparison of Nd:YAG 1064 nm and diode 810 nm laser wavelengths in brain interstitial laser photocoagulation (ILP). Specific goals were to identify potential complications and physical characteristics of the thermal damage at both wavelengths prior to undertaki...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1997)21:1<50::aid-lsm8>3.0
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Although several studies on laser-assisted hair removal have been published, data on long-term follow-up are few. The present study investigated the long-term efficacy and safety of normal-mode ruby laser pulses on hair removal. STUDY DESIGN/MATERIALS AND METHODS:The normal-mode ruby laser (Ep...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(2000)26:2<177::aid-lsm8>3.
更新日期：2000-01-01 00:00:00
abstract：:The fourth harmonic wavelength (266 nm) of a neodymium YAG laser was used to cut precise grooves on the surface of the human cornea. Well-controlled cuts were made using the laser operating at 1.3 kHz. The width of the grooves was 2-3 micron. The depth could be controlled by varying the amount of laser exposure. ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900050405
更新日期：1985-01-01 00:00:00
abstract：:A synthetic contact sapphire endoprobe attached to the quartz fiber of a neodymium:yttrium aluminum garnet (Nd:YAG) laser had been used in the transurethral treatment of bladder tumors. A total of 68 operations have been carried out in 48 patients. The contact probe was placed directly into the tumor under direct visi...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900070616
更新日期：1987-01-01 00:00:00
abstract：:We describe our experience and the problems we encountered organizing an autonomous surgical unit in which the equipment and organization enable three lasers to be used in may different applications in medicine and surgery. The three lasers--CO2, Nd:YAG, and argon--may now be used by all the departments concerned with...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.1900030102
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Knowledge about optical parameters and the resultant light distribution in laser-treated tissue is important for predicting the effects of laser-induced thermotherapy of liver metastases (LITT). MATERIALS AND METHODS:The absorption and scattering coefficients as well as the anisotropy factors ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/(sici)1096-9101(1998)23:4<194::aid-lsm2>3.
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:CO2 laser cordectomy has been the workhorse of laser surgery for early glottic squamous cell carcinoma (GSCC) since the early 1970s. During the last decades, potassium titanyl phosphate (KTP) laser surgery for early GSCC gained popularity, introducing the tumor ablation technique. Yet, there a...
journal_title：Lasers in surgery and medicine
pub_type：
doi：10.1002/lsm.23202
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:This preliminary report describes a new laser-assisted treatment option for the emerging complication of bisphosphonate related osteonecrosis (BON) of the jaw. MATERIALS AND METHODS:In eight tumour patients (three women, five men) ten bony lesions in the maxilla and mandible in the course of ...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.20730
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:Photodynamic therapy is a proven therapeutic modality in the management of variety of pathologies involving the human body. Our aim in this clinical study is to prospectively evaluate the outcome following interstitial photodynamic therapy for patients with vascular anomalies. Patients' reports on quality ...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.21058
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Complete neurosurgical resection of intracranial meningiomas is essential to avoid residual tumor tissue and thus minimize the risk of tumor recurrence. However, local recurrence of meningiomas is not uncommon mainly due to insufficient intraoperative detection of residual tumor tissue within ...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.23294
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Inhibition of cyclooxygenase (COX) and prostaglandin E(2) (PGE(2)) protects cells against cell injury in specific pathophysiological situations: inflammation and oxidative stress. Although the anti-inflammatory effects have been reported in clinical fields for specific wavelength irradiation d...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.20533
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Port-wine stain (PWS) is a congenital, progressive vascular malformation of the dermis. The use of optical coherence tomography (OCT) for the characterization of blood vessels in PWS skin has been demonstrated by several groups. In the past few years, advances in OCT technology have greatly in...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22194
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Photo-aging in Chinese often presents with benign pigmentary lesions. Q-switched lasers for pigmentary lesions in Asians had reported a risk of post-inflammatory hyperpigmentation (PIH) up to 25%. Longer pulse widths in the millisecond domains were advocated with reduced risk of PIH. Recently,...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.22443
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:For Asian skin, recent "non-ablative" skin rejuvenation techniques have become the focus of attention for darker complected patients. In our earlier research, we have shown that intense pulsed light (IPL) technology can be applied to Asian skin with a high degree of safety and efficacy. In thi...
journal_title：Lasers in surgery and medicine
pub_type： 杂志文章
doi：10.1002/lsm.10036
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Postoperative scarring after thyroidectomy is a problem for both patients and clinicians. Recently, both non-ablative and ablative fractional laser (NFL and AFL) systems have attracted attention as potential therapies for the revision of thyroidectomy scars. The present split-scar study was des...
journal_title：Lasers in surgery and medicine
pub_type： 临床试验,杂志文章
doi：10.1002/lsm.22297
更新日期：2014-12-01 00:00:00
