Optical properties of native and coagulated human liver tissue and liver metastases in the near infrared range.

Abstract:

BACKGROUND AND OBJECTIVE:Knowledge about optical parameters and the resultant light distribution in laser-treated tissue is important for predicting the effects of laser-induced thermotherapy of liver metastases (LITT). MATERIALS AND METHODS:The absorption and scattering coefficients as well as the anisotropy factors and the optical penetration depths of human liver tissue and colorectal liver metastases were determined at 850, 980, and 1,064 nm under native and thermocoagulated conditions. RESULTS:Liver metastases had a lower anisotropy factor, absorption, and scattering coefficient than healthy liver (P < 0.01), resulting in a significantly higher optical penetration depth in metastatic tissue. Coagulation significantly changes the optical parameters by reducing the optical penetration depth in both tissue types (P < 0.01). CONCLUSIONS:A greater optical penetration depth in metastatic tissue is advantageous for LITT, since larger tumor volumes can be coagulated. At the same time, an adjustment of the application parameters during LITT is necessary to achieve optimal therapeutic success.

journal_name

Lasers Surg Med

authors

Germer CT,Roggan A,Ritz JP,Isbert C,Albrecht D,Müller G,Buhr HJ

doi

10.1002/(sici)1096-9101(1998)23:4<194::aid-lsm2>3.

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

194-203

issue

4

eissn

0196-8092

issn

1096-9101

pii

10.1002/(SICI)1096-9101(1998)23:4<194::AID-LSM2>3.

journal_volume

23

pub_type

杂志文章
  • High power-pulsed Nd:YAG laser as a new stimulus to induce BMP-2 expression in MC3T3-E1 osteoblasts.

    abstract:BACKGROUND AND OBJECTIVE:High-power laser has recently become a physical stimulus for bone regeneration. Little is known about how high-power laser irradiation affects osteoblast differentiation. This study investigated osteoblast responses to high-power laser and combined irradiation with BMP-2 treatment. STUDY DESIG...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20870

    authors: Kim IS,Cho TH,Kim K,Weber FE,Hwang SJ

    更新日期:2010-08-01 00:00:00

  • Pulmonary blast injury in mice: a novel model for studying blast injury in the laboratory using laser-induced stress waves.

    abstract:BACKGROUND AND OBJECTIVES:Primary blast injury is produced by shock waves. Blast injuries to lungs are extremely critical threats to survival, but their etiology is largely undefined. The majority of animal models for these injuries use explosive or complex experimental settings, limiting the laboratory study of blast ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20899

    authors: Satoh Y,Sato S,Saitoh D,Tokuno S,Hatano B,Shimokawaji T,Kobayashi H,Takishima K

    更新日期:2010-04-01 00:00:00

  • Comparison of non-ablative and ablative fractional laser treatments in a postoperative scar study.

    abstract:BACKGROUND AND OBJECTIVE:Postoperative scarring after thyroidectomy is a problem for both patients and clinicians. Recently, both non-ablative and ablative fractional laser (NFL and AFL) systems have attracted attention as potential therapies for the revision of thyroidectomy scars. The present split-scar study was des...

    journal_title:Lasers in surgery and medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/lsm.22297

    authors: Shin JU,Gantsetseg D,Jung JY,Jung I,Shin S,Lee JH

    更新日期:2014-12-01 00:00:00

  • Lasers in ophthalmology.

    abstract::This article reviews the principle uses of ophthalmic lasers, providing historical background with an emphasis on new applications and areas of investigation. Ophthalmic photocoagulation was the first medical laser application and has restored or maintained vision in millions of people. More recently, photodisruption ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,评审

    doi:10.1002/lsm.1900170203

    authors: Krauss JM,Puliafito CA

    更新日期:1995-01-01 00:00:00

  • Spot size reduction in coupling of laser to micromanipulator in laser microsurgery by fiberoptic link.

    abstract:BACKGROUND AND OBJECTIVE:In coupling laser with micromanipulator through fiberoptics, the resulting diameter of the spot is limited by the laws of geometrical optics, because of the high numerical aperture (N.A.) of fiberoptic radiation. A new method for the reduction of spot size diameter is suggested. STUDY DESIGN/M...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900170110

    authors: Logunov SL,Lemberg VG

    更新日期:1995-01-01 00:00:00

  • Determination of the dynamics of restored teeth by 3D electronic speckle pattern interferometry.

    abstract:BACKGROUND AND OBJECTIVES:The difficulties typically encountered in studying the effects of restorations on tooth reinforcement are often due to the 3-dimensional (3D) nature of deformation. Therefore, electronic 3D-Speckle-Interferometry (3D-ESPI) was used to assess the impact of different restorative materials on the...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20036

    authors: Lang H,Rampado M,Müllejans R,Raab WH

    更新日期:2004-01-01 00:00:00

  • Gross and microscopic changes in the viscera induced by photodynamic therapy applied to the lower abdomen of intact rats.

    abstract::Photodynamic therapy (PDT) is a promising approach to the treatment of cancer. Preferential retention of the photosensitizer by malignant tissue has been considered a hallmark of this treatment modality. However, photosensitivity can be observed in normal, non-neoplastic tissues, and the present study investigated the...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900110110

    authors: Chazen MD,Baggs RB,Gibson SL,Albert MS,Hilf R

    更新日期:1991-01-01 00:00:00

  • Is an anesthesiologist's presence justified during therapeutic laser endoscopy?

    abstract::Diagnostic endoscopy has generally been done under intravenous sedation. Diazepam and meperidine are the two most frequent drugs used. Even though these drugs produce sedation, analgesia, and amnesia, they do not provide a quiet field. Therapeutic laser endoscopy requires a quiet field. We conclude that an anesthesiol...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900070311

    authors: Lichtiger M,Russin DJ

    更新日期:1987-01-01 00:00:00

  • Tooth caries detection by curve fitting of laser-induced fluorescence emission: a comparative evaluation with reflectance spectroscopy.

    abstract:BACKGROUND AND OBJECTIVES:Nitrogen laser-induced fluorescence (LIF) spectra of sound tooth consists of two broad bands centered at 440 and 490 nm, with two apparent side bands on either side. In order to locate the exact peak position of these bands and to effectively utilize the LIF spectral signatures for detection o...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20229

    authors: Subhash N,Thomas SS,Mallia RJ,Jose M

    更新日期:2005-10-01 00:00:00

  • In vitro resistance of articular chondrocytes to 5-Aminolevulinic acid based photodynamic therapy.

    abstract:OBJECTIVE:5-Aminolevulinic acid based photodynamic therapy (5-ALA-PDT) has revealed promising results in the treatment of inflammatory joint diseases due to the sensitivity of inflamed synovial tissue. For 5-ALA-PDT to be safe and beneficial for intra-articular applications, resistance of chondrocytes is essential to p...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20625

    authors: Egli RJ,Di Criscio A,Hempfing A,Schoeniger R,Ganz R,Hofstetter W,Leunig M

    更新日期:2008-04-01 00:00:00

  • Parameters in fractional laser assisted delivery of topical anesthetics: Role of laser type and laser settings.

    abstract:BACKGROUND AND OBJECTIVES:Efficacy of topical anesthetics can be enhanced by pretreatment of the skin with ablative fractional lasers. However, little is known about the role of parameters such as laser modality and laser density settings in this technique. Aims of this study were to compare the efficacy of pretreatmen...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/lsm.22936

    authors: Meesters AA,Nieboer MJ,Kezic S,de Rie MA,Wolkerstorfer A

    更新日期:2018-10-01 00:00:00

  • Exploiting the aiming beam to increase the safety of laser lithotripsy: Experimental evaluation of light reflection and fluorescence.

    abstract:BACKGROUND AND OBJECTIVES:In Holmium laser lithotripsy, usually, the surgeon is guided by a visible beam superimposing the infrared (IR) treatment radiation. It has been shown that a green aiming beam excites stone autofluorescence. This fluorescence signal can be used for calculi detection to check the correct fiber p...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.23154

    authors: Lange B,Cordes J,Brinkmann R

    更新日期:2020-06-01 00:00:00

  • In vitro evaluation of ablation parameters of normal and fibrous aorta using smooth excimer laser coronary angioplasty.

    abstract::A modified excimer laser energy delivery system was used to irradiate 100 segments of normal and fibrous aorta in vitro. The laser beam was scanned into 8 fiber bundles consisting of 50 fibers each resulting in a reduction of the applied pulse energy. The total repetition rate was increased to 150 Hz in order to keep ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900130605

    authors: Xie DY,Hassenstein S,Oberhoff M,Hanke H,Baumbach A,Hohla K,Haase KK,Karsch KR

    更新日期:1993-01-01 00:00:00

  • Interstitial laser thermotherapy of a rat liver tumour: effect of hepatic inflow occlusion.

    abstract:BACKGROUND AND OBJECTIVE:Interstitial laser thermotherapy was used to treat rat liver tumours. The aim was to investigate the influence of temperature and temporary hepatic inflow occlusion on tumour growth and blood perfusion. STUDY DESIGN/MATERIALS AND METHODS:Liver tumours were treated at 44°C at the tumour border ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.21024

    authors: Sturesson C,Ivarsson K,Stenram U,Andersson-Engels S,Tranberg KG

    更新日期:2011-01-01 00:00:00

  • CO2 Laser Cordectomy Versus KTP Laser Tumor Ablation for Early Glottic Cancer: A Randomized Controlled Trial.

    abstract:BACKGROUND AND OBJECTIVES:CO2 laser cordectomy has been the workhorse of laser surgery for early glottic squamous cell carcinoma (GSCC) since the early 1970s. During the last decades, potassium titanyl phosphate (KTP) laser surgery for early GSCC gained popularity, introducing the tumor ablation technique. Yet, there a...

    journal_title:Lasers in surgery and medicine

    pub_type:

    doi:10.1002/lsm.23202

    authors: Lahav Y,Cohen O,Shapira-Galitz Y,Halperin D,Shoffel-Havakuk H

    更新日期:2020-09-01 00:00:00

  • Intraoperative Raman spectroscopy of soft tissue sarcomas.

    abstract:BACKGROUND AND OBJECTIVE:Soft tissue sarcomas (STS) are a rare and heterogeneous group of malignant tumors that are often treated through surgical resection. Current intraoperative margin assessment methods are limited and highlight the need for an improved approach with respect to time and specificity. Here we investi...

    journal_title:Lasers in surgery and medicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/lsm.22564

    authors: Nguyen JQ,Gowani ZS,O'Connor M,Pence IJ,Nguyen TQ,Holt GE,Schwartz HS,Halpern JL,Mahadevan-Jansen A

    更新日期:2016-10-01 00:00:00

  • Acute response of the arterial wall to pulsed laser irradiation.

    abstract::This study was designed to examine the acute response of normal arterial wall to pulsed laser irradiation. Irradiation with an Excimer or a Holmium YAG laser was performed in 15 normal iliac sites of 8 male New Zealand white rabbits. The excimer laser was operated at 308 nm, 25 Hz, 50 mJ/mm2/pulse, and 135 nsec/pulse ...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900130404

    authors: Nakamura F,Kvasnicka J,Levame M,Lange F,Bousbaa H,Geschwind HJ

    更新日期:1993-01-01 00:00:00

  • Tissue ablation and gas formation of two excimer laser systems: an in vitro evaluation on porcine aorta.

    abstract:BACKGROUND AND OBJECTIVE:The relationship between tissue ablation volume and the formation of insoluble gas of the currently available excimer laser systems is unknown. This aspect was evaluated in two excimer laser systems. STUDY DESIGN/MATERIALS AND METHODS:We measured tissue ablation volume and gas production of tw...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9101(1996)18:2<197::AID-LSM11>3

    authors: Appelman YE,Piek JJ,Verhoofstad GG,Gijsbers GH,Van Gemert MJ

    更新日期:1996-01-01 00:00:00

  • Pilot clinical study of a novel minimally invasive bipolar microneedle radiofrequency device.

    abstract:BACKGROUND AND OBJECTIVES:Noninvasive bipolar and monopolar radiofrequency (RF) deep dermal heating devices have previously been described. A novel minimally invasive RF device employing a bipolar microneedle electrode system is introduced and its resultant thermal effects on human skin in vivo were characterized for t...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20687

    authors: Hantash BM,Renton B,Berkowitz RL,Stridde BC,Newman J

    更新日期:2009-02-01 00:00:00

  • A split-face study of intense pulsed light on photoaging skin in Chinese population.

    abstract:BACKGROUND AND OBJECTIVES:Intense pulsed light (IPL) is regarded as the gold standard of nonablative photo-rejuvenation. Yet there is still a need to observe its efficacy and safety on dark skin using a split-face module. STUDY DESIGN/MATERIALS AND METHODS:Twenty-four Chinese women with photoaging were enrolled in thi...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/lsm.20889

    authors: Li YH,Wu Y,Chen JZ,Zhu X,Xu YY,Chen J,Dong GH,Gao XH,Chen HD

    更新日期:2010-02-01 00:00:00

  • Evaluation of changes in oxygen tension as indicators of RIF-1 tumor response to Nd:YAG laser heating.

    abstract::Heat-induced oxygen tension changes in RIF-1 tumors in C3H male mice were analyzed in an attempt to correlate these changes with tumor response to Nd:YAG laser heating. A low power, microprocessor-controlled Nd:YAG laser was used to superficially heat 250-300 mm3 tumors to base temperatures of 44, 45, 46, or 48 degree...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900130308

    authors: Fahy AK,Waldow SM

    更新日期:1993-01-01 00:00:00

  • Laser oncology in Italy: experimental research and clinical applications at the National Cancer Institute, Milan.

    abstract::CO2, Nd:YAG, and argon lasers have been used for 5 years for experimental and clinical procedures at the National Cancer Institute of Milan under the auspices of the National Research Council. Experimental data regarding tumor cell spread through lymphatic and hematic channels and cell viability in the fumes after CO2...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900020409

    authors: Emanuelli H,Bandieramonte G,Marchesini R,Fava G,Rodari A,Colombo MP,Costa A,Spinelli P,Zunino F,Chiesa F,Cascinelli N,Andreola S,Pariente R,Canti GF

    更新日期:1983-01-01 00:00:00

  • CO2 laser annular thermokeratoplasty: a preliminary study.

    abstract::Since most techniques of refractive surgery currently in use or being developed have the potential for significant side effects, there is a need for investigating alternative procedures. We herein report on the use of a pulsed CO2 laser beam delivered through a pair of complementary axicons to produce a ring of stroma...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900120305

    authors: Chandonnet A,Bazin R,Sirois C,Bélanger PA

    更新日期:1992-01-01 00:00:00

  • Laser-assisted end-to-end BioWeld anastomosis in an ovine model.

    abstract::The BioWeld tube, an albumin-based exovascular stent, has been used for microsurgical anastomoses and compared to conventional sutures. The study presented investigated the potential of the BioWeld tube for vascular anastomosis in larger vessels. Laser-assisted BioWeld anastomoses were compared to conventional-sutured...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20541

    authors: Wright B,Vicaretti M,Schwaiger N,Wu J,Trickett R,Morrissey L,Rohanizadeh R,Fletcher J,Maitz P,Harris M

    更新日期:2007-09-01 00:00:00

  • The anti-inflammatory mechanism of 635 nm light-emitting-diode irradiation compared with existing COX inhibitors.

    abstract:BACKGROUND AND OBJECTIVES:Inhibition of cyclooxygenase (COX) and prostaglandin E(2) (PGE(2)) protects cells against cell injury in specific pathophysiological situations: inflammation and oxidative stress. Although the anti-inflammatory effects have been reported in clinical fields for specific wavelength irradiation d...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.20533

    authors: Lim W,Lee S,Kim I,Chung M,Kim M,Lim H,Park J,Kim O,Choi H

    更新日期:2007-08-01 00:00:00

  • A Prospective Study in the Treatment of Lentigines in Asian Skin Using 532 nm Picosecond Nd:YAG Laser.

    abstract:BACKGROUND AND OBJECTIVE:To evaluate safety and efficacy of treatment with the picosecond Nd:YAG 532 nm for lentigines in Asian skin. STUDY DESIGN/MATERIALS AND METHODS:This was a prospective, open-label cohort study, using a novel picosecond 532-nm laser for the treatment of facial lentigines. Subjects received up to...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.23103

    authors: Chan MWM,Shek SY,Yeung CK,Chan HH

    更新日期:2019-11-01 00:00:00

  • Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent.

    abstract:OBJECTIVE:A relatively low level of lysosomal photodamage has been shown capable of promoting the efficacy of photodamage simultaneously or subsequently directed to mitochondrial/ER sites. The procedure has hitherto involved the use of two photosensitizing agents that require irradiation at two different wavelengths an...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.22813

    authors: Rizvi I,Obaid G,Bano S,Hasan T,Kessel D

    更新日期:2018-07-01 00:00:00

  • Double pass 595 nm pulsed dye laser at a 6 minute interval for the treatment of port-wine stains is not more effective than single pass.

    abstract:BACKGROUND:Pulsed dye laser (PDL) is the first choice for treatment of port wine stains (PWS). However, outcome is highly variable and only a few patients achieve complete clearance. The objective of the study was to compare efficacy and safety of single pass PDL with double pass PDL at a 6 minute interval. METHODS:We...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/lsm.22011

    authors: Peters MA,van Drooge AM,Wolkerstorfer A,van Gemert MJ,van der Veen JP,Bos JD,Beek JF

    更新日期:2012-03-01 00:00:00

  • Human albumin solders for clinical application during laser tissue welding.

    abstract:BACKGROUND AND OBJECTIVE:Fifty percent human albumin solder significantly improves weld strength when compared to lower concentrations [Wright et al., ASLMS meeting, April, 1995]. We developed a method for preparing 50% human albumin that may be considered compatible for clinical applications. STUDY DESIGN/MATERIALS A...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9101(1996)19:1<2::AID-LSM1>3.0.

    authors: Poppas DP,Wright EJ,Guthrie PD,Shlahet LT,Retik AB

    更新日期:1996-01-01 00:00:00

  • Electron microscopy of CO2-laser-induced effects in human fibrocartilage.

    abstract::Previous reports of effects of CO2 laser energy on human fibrocartilage suggest thermal injury extends to a depth of approximately 70 microns from the target surface with power settings of 35 W and exposure times of 0.5 seconds. The present study was undertaken to look for more subtle evidence of thermal alteration of...

    journal_title:Lasers in surgery and medicine

    pub_type: 杂志文章

    doi:10.1002/lsm.1900070209

    authors: Whipple TL,Marotta JJ,May TC,Caspari RB,Meyers JF

    更新日期:1987-01-01 00:00:00