Abstract:
BACKGROUND:Although extraordinary advances have been made in the management of advanced coronary artery disease, little progress has been made in its prevention. Traditional screening methods utilizing risk factor profiles and exercise treadmill tests have failed to identify populations who will subsequently have coronary events with a high degree of predictive accuracy. METHODS:We review the pathobiologic basis and clinical utility of electron beam computed tomography (EBCT) to detect coronary artery calcium as a screening tool for subclinical coronary artery disease. Because EBCT is able to perform subsecond imaging of the heart, it can detect and quantitate coronary artery calcium with a high degree of precision. Coronary artery calcium is a marker of complex atherosclerosis. RESULTS:Over 4,000 asymptomatic patients in several series have been studied with EBCT and followed prospectively for an average of 42 months (range 37-72 months). A positive scan is associated with a risk ratio for future coronary events of 8.7 (95% confidence interval 2.67 to 28.13). These data indicate that EBCT has the ability to detect subclinical coronary artery disease and predict future coronary events better than any previous existing method or technology. CONCLUSION:EBCT coronary artery screening may prove to be a valuable adjunct to the traditional methods for the detection of subclinical coronary artery disease and to identify those who would benefit from focused preventive therapies.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Rich S,McLaughlin VVdoi
10.1006/pmed.2000.0813subject
Has Abstractpub_date
2002-01-01 00:00:00pages
1-10issue
1eissn
0091-7435issn
1096-0260pii
S0091743500908132journal_volume
34pub_type
杂志文章,评审abstract::Although socioeconomic, behavioural, psychological, and biological factors have been individually linked to multimorbidity, data on the importance of these factors are limited. Our study aimed to determine the leading predictors for multimorbidity of chronic conditions in middle-aged Australian adults using machine le...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2020.106260
更新日期:2020-12-01 00:00:00
abstract::The goal of this study is to provide, for the United States, estimates for gun-owning and non-owning households in terms of firearm and non-firearm suicides and suicide attempts. To make these ballpark estimates I combine a half-dozen known "facts" about suicide (e.g., households with firearms are at approximately 3× ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2018.12.003
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Walking is a widely used approach to increase physical activity levels in obese patients. In this paper, we investigate the precision and accuracy of an ankle-worn dual-axis accelerometer (Stepwatch) and investigate its potential application as a predictor of energy expenditure. METHODS:Twenty healthy subje...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2005.07.006
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:We assessed the effectiveness of the Luoghi di Prevenzione-Prevention Grounds school-based smoking prevention programme. METHODS:We undertook a cluster randomized controlled trial of 989 students aged 14-15 years in 13 secondary schools located in Reggio Emilia, Italy. The intervention consisted of the "Smok...
journal_title:Preventive medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ypmed.2014.01.004
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:To investigate the effect of screening and five years of multi-factorial lifestyle intervention on changes in alcohol intake in a general population. METHODS:The study was a pre-randomized intervention study on lifestyle, Inter99 (1999-2006), Copenhagen, Denmark. Participants in the intervention group (n=6 091...
journal_title:Preventive medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ypmed.2009.06.007
更新日期:2009-08-01 00:00:00
abstract::Group Health Cooperative (GHC) of Puget Sound is a prepaid health plan with 285,000 enrollees and 340 physicians. In 1978 a "criterion analysis" approach was instituted to develop medical staff recommendations about preventive care. By 1979, two recommendations evolved discouraging the "routine" use of: (a) chest X ra...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(83)90247-5
更新日期:1983-05-01 00:00:00
abstract:BACKGROUND:Few studies have examined the long-term adherence to a yearlong exercise intervention among postmenopausal women. We examined the patterns of adherence to a yearlong exercise intervention and the influence of demographic, physiologic, and psychosocial variables on patterns of adherence among 173 sedentary, o...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ypmed.2004.04.017
更新日期:2004-12-01 00:00:00
abstract::The objective of this study was to determine whether attainment of clinical and lifestyle targets varied by race and sex among adults with diabetes onset in older adulthood. This study included 1420 black and white adults from the REGARDS study without diabetes at baseline (2003-07) but with diabetes onset at the foll...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2020.106217
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The relationship between physical activity (PA) and the development of hip/knee osteoarthritis (OA) has not been clearly defined. The purpose of this study was to develop a method to quantify PA-related joint stress and to assess its influence on the risk of hip/knee OA. METHODS:Participants in a large long...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/s0091-7435(03)00018-5
更新日期:2003-05-01 00:00:00
abstract::Black and Hispanic communities in the U.S. have endured a disproportionate burden of COVID-19-related morbidity and mortality. Racial and ethnic health disparities such as these are frequently aggravated by inequitable access to healthcare resources in disadvantaged communities. Yet, no known studies have investigated...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2020.106282
更新日期:2020-12-01 00:00:00
abstract::China's one-child policy (1979-2015) has affected Chinese parenting practices and children's health behaviors and also may have contributed to increased childhood obesity. However, very limited research has investigated the association between one-child policy and childhood obesity. We examined characteristics of sing...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.07.018
更新日期:2017-10-01 00:00:00
abstract::Physical activity guidelines for cancer survivors issued by the American Cancer Society and the American College of Sports Medicine emphasize the essential role of a health care provider (HCP) in counseling cancer survivors to achieve healthier lifestyles. However, research has not established whether HCP's recommenda...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.01.010
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to identify patterns of mammogram and Papanicolaou (Pap) screenings among Mexican American women ages 67 and over. METHODS:Data on 1,403 Mexican American women from the Hispanic Established Population for the Epidemiological Study of the Elderly, a cohort study of community-dwellin...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2001.0880
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVE:This paper assesses the potential benefits of increased walking and reduced obesity associated with taking public transit in terms of dollars of medical costs saved and disability avoided. METHODS:I conduct a new analysis of a nationally representative U.S. transportation survey to gauge the net increase in ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2007.10.004
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Obesity is associated with several chronic conditions, increased medical costs, and premature death. Proper assessment of changes in body weight is crucial to control the spread of obesity. We used data from the Behavioral Risk Factor Surveillance System to explore how adults in the United States recall their...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.04.019
更新日期:2012-08-01 00:00:00
abstract::Using participants (N = 1733) drawn from the nationally representative longitudinal Young Finns Study (YFS) we estimate the effect of education on depressive symptoms. In 2007, when the participants were between 30 and 45 years old, they reported their depressive symptoms using a revised version of Beck's Depression I...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2018.08.026
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of the Melbourne Infant Feeding, Activity and Nutrition Trial (InFANT) Program according to maternal education and age. METHODS:A cluster-randomised controlled trial involving 542 mother/infant pairs from 62 existing first-time parent groups was conducted in 2008 in Melbourne, Aus...
journal_title:Preventive medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ypmed.2013.10.021
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Previous studies investigating predictors of influenza vaccine acceptance have focused on high-risk patients or health care workers. Few studies have examined flu shot acceptance among healthy adults in workplace settings, even though influenza vaccine is recommended for this group as well. METHODS:Two stud...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1999.0535
更新日期:1999-10-01 00:00:00
abstract::Several randomized trials have demonstrated that HPV-based cervical cancer screening is more effective than cytology-based screening. A pooled analysis of long-term follow-up data from these trials has shown reduced cervical cancer mortality in women screened with HPV compared to cytology. As a consequence, many healt...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.12.040
更新日期:2017-05-01 00:00:00
abstract:UNLABELLED:Red blood cell distribution width (RDW) is a novel biomarker indicative of cardiovascular disease. However, little research has examined the association of muscle strengthening activities (MSA) on RDW. OBJECTIVE:Examine the association between MSA and RDW among a national sample of U.S. adults. METHODS:Dat...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2015.01.011
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:We investigated the impact of mental health on the decline in higher activities of daily living (ADL) defined in terms of social role performance (SR, the highest ADL), intellectual activity (IA), and instrumental ADL (IADL), as well as the onset of basic ADL disability. METHODS:Six hundred older adults were...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2007.12.007
更新日期:2008-05-01 00:00:00
abstract::Skin cancer presents a significant public health burden in Australia. The present study aimed to supplement population-based estimates of sun protection behaviour by examining setting-specific trends in directly observed sun protection in public outdoor leisure settings. Repeated cross-sectional observational surveys ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2020.106230
更新日期:2020-10-01 00:00:00
abstract::This investigation examined the relationship between lifestyle, as defined by common health habits, and symptoms of depression in a general community sample. The study was conducted using data from a longitudinal survey involving four interviews of 1,003 Los Angeles County adults. The survey focused on the epidemiolog...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(88)90061-8
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:Residency training is an ideal time to prepare pediatricians to address tobacco, although few programs provide the necessary training. Barriers to training include competing priorities, lack of resources, and unavailability of expertise. Solutions for Smoking, a hybrid CD-ROM and web site training program fo...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ypmed.2004.02.008
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Smokers who identified smoking cessation as the primary activity they could undertake to improve their health were compared with smokers who did not identify smoking cessation. Examined factors included personal characteristics, health status, smoking attitudes and behaviors, and social factors. METHODS:Sub...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1995.1063
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Elevated total homocysteine (tHcy) levels (>/= 15 micromol/L), resulting from enzyme or vitamin deficiency, increase risk for cardiac, cerebral, and peripheral vascular disease. This study examines tHcy levels in an Israeli population and the relationship to vitamin status and disease. The need for screening...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2003.09.001
更新日期:2003-12-01 00:00:00
abstract::This report describes a systematic literature review of voucher and related monetary-based contingency management (CM) interventions for substance use disorders (SUDs) over 5.2years (November 2009 through December 2014). Reports were identified using the search engine PubMed, expert consultations, and published biblio...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ypmed.2016.08.008
更新日期:2016-11-01 00:00:00
abstract::The Framework Convention on Tobacco Control, a global health treaty ratified by over 175 countries, calls on countries to ensure that tobacco packages carry health warning labels (HWLs) describing the harmful effects of tobacco use. We assessed the extent of compliance with 14 countries' HWL requirements. Unique cigar...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2016.10.006
更新日期:2016-12-01 00:00:00
abstract::Only a small fraction of the health-care dollar is directed toward lifestyle changes that would reduce the social burden from cardiovascular diseases (CVD). Here we discuss the challenge, opportunity, methods, and potential for managed care to implement risk reduction strategies and preventive care. A systematic team ...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1006/pmed.1999.0563
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Adequate care for patients with cardiovascular risks requires an adequate practice organization. Educational outreach visits are a promising approach to modifying professional behavior. We aimed to assess whether the quality of cardiovascular preventive care in general practice can be improved through a comp...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1006/pmed.2002.1095
更新日期:2002-11-01 00:00:00