Diagnostic difficulty in infants and children.

Abstract:

:Making an accurate diagnosis is the first and most critical step in the treatment of pediatric epilepsy, but it can be a daunting challenge for clinicians. Seizure types and syndromes in infants and very young children do not present with the same clarity and consistency as in adults. Work is currently being done to revise traditional International League Against Epilepsy classifications to make it easier for physicians to accurately diagnose and effectively treat epilepsy in infants and young children. A simplified approach can be formed by combining some of the International League Against Epilepsy recommendations with new findings on the clinical manifestations of pediatric seizures. Refinements in the new system will occur as knowledge of the pathophysiology of epilepsy and genetic susceptibilities expands, but even in its early stages the new classification system has much to offer, resulting in improved patient care and more effective management of the disease.

journal_name

J Child Neurol

authors

Nordli DR Jr

doi

10.1177/08830738020170010401

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

S28-35

eissn

0883-0738

issn

1708-8283

journal_volume

17 Suppl 1

pub_type

杂志文章,评审
  • Acute disseminated encephalomyelitis in North Indian children: clinical profile and follow-up.

    abstract::Acute disseminated encephalomyelitis in children is not uncommon in developing countries, yet there is little systematic documentation of its clinical profile and follow-up. We studied the clinical and neuroradiologic features of acute disseminated encephalomyelitis in 52 consecutive children. Clinical details, magnet...

    journal_title:Journal of child neurology

    pub_type: 临床试验,杂志文章

    doi:10.1177/08830738060210100201

    authors: Singhi PD,Ray M,Singhi S,Kumar Khandelwal N

    更新日期:2006-10-01 00:00:00

  • The fetal cerebellum: development and common malformations.

    abstract::The cerebellum undergoes a protracted development, making it particularly vulnerable to a broad spectrum of developmental events. Acquired destructive and hemorrhagic insults may also occur. The main steps of cerebellar development are reviewed. The normal imaging patterns of the cerebellum in prenatal ultrasound and ...

    journal_title:Journal of child neurology

    pub_type: 杂志文章,评审

    doi:10.1177/0883073811420148

    authors: Garel C,Fallet-Bianco C,Guibaud L

    更新日期:2011-12-01 00:00:00

  • The 14 & 6-associated clinical complex: a rejected hypothesis revisited.

    abstract::The 14 & 6 Hz positive spike phenomenon is generally considered a normal variant finding. Our experience prompted this re-evaluation, which consisted of three parts: In children referred for sleep electroencephalograms (EEGs), 100 children with normal EEG and 100 with 14 & 6--the 14 & 6 correlated with behavior disord...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307388700200207

    authors: DeLong GR,Rosenberger PB,Hildreth S,Silver I

    更新日期:1987-04-01 00:00:00

  • Kindergarten readiness skills in children with sickle cell disease: evidence of early neurocognitive damage?

    abstract::Young children with sickle cell disease are at risk of brain damage, including stroke. We tested the hypothesis that such patients are also at risk of cognitive impairment. We characterized the cognitive ability of kindergarten children to minimize the effect of disease-related school absence. The Memphis City Schools...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307380201700204

    authors: Steen RG,Hu XJ,Elliott VE,Miles MA,Jones S,Wang WC

    更新日期:2002-02-01 00:00:00

  • Trihexyphenidyl improves motor function in children with dystonic cerebral palsy: a retrospective analysis.

    abstract::There are conflicting reports regarding the efficacy of trihexyphenidyl, an anticholinergic drug, for treatment of dystonia in cerebral palsy. The author hypothesized that trihexyphenidyl may be more effective in specific subgroups and performed a retrospective analysis of 31 children (8.2 ± 5.8 years) with dystonia f...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073810392582

    authors: Ben-Pazi H

    更新日期:2011-07-01 00:00:00

  • Balo concentric sclerosis in children: a case series.

    abstract::Baló concentric sclerosis is a unique and rare phenomenon in demyelinating disease. Typically thought of as a subtype of multiple sclerosis, Baló concentric sclerosis is characterized pathologically by striking rings of demyelination alternating with areas of preserved myelination. Its exact prevalence in adult and es...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073813517294

    authors: Linnoila J,Chitnis T

    更新日期:2014-05-01 00:00:00

  • Schilder's disease: case study with serial neuroimaging.

    abstract::Schilder's myelinoclastic diffuse sclerosis is a rare sporadic demyelinating disease that usually affects children between 5 and 14 years old. The disease often mimics intracranial neoplasm or abscess. We report a 9-year-old girl with Schilder's disease who presented with left hemiparesis. Cranial computed tomography ...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/08830738030180011301

    authors: Kurul S,Cakmakçi H,Dirik E,Kovanlikaya A

    更新日期:2003-01-01 00:00:00

  • Neurologic presentations of mitochondrial disorders.

    abstract::This article describes the neurologic presentations of children with mitochondrial disorders. The charts of 42 children with highly suspect mitochondrial disorders were reviewed. Thirty-seven children were diagnosed as having definite mitochondrial disorders based on a suggestive clinical presentation and at least one...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307380001500110

    authors: Nissenkorn A,Zeharia A,Lev D,Watemberg N,Fattal-Valevski A,Barash V,Gutman A,Harel S,Lerman-Sagie T

    更新日期:2000-01-01 00:00:00

  • Joint Position Sense Testing in Young Children.

    abstract::The standard physical examination evaluation for a proprioception abnormality depends upon the patient's ability to follow directions and respond to the examiner, a skill not yet developed in toddlers. This study demonstrates a new proprioception examination method that may allow for better localization of lesions and...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073818812348

    authors: Gray EM,Tomlison KG,Kileny S,Leber SM

    更新日期:2019-03-01 00:00:00

  • Long-term Cognitive Outcome of Children With Parenchymal Neurocysticercosis: A Prospective Observation Study.

    abstract::To study the cognitive profile and scholastic performance of children with parenchymal neurocysticercosis. A total of 500 children with a diagnosis of neurocysticercosis and epilepsy registered in our pediatric neurocysticercosis clinic between January 1996 and December 2002 were enrolled. Patients were evaluated for ...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073818766985

    authors: Singhi P,Malhi P,Suthar R,Deo B,Khandelwal NK

    更新日期:2018-06-01 00:00:00

  • Children with developmental disabilities in India: age of initial concern and referral for rehabilitation services, and reasons for delay in referral.

    abstract::This study aimed to identify the age at first concern and age at referral for rehabilitation services in children with developmental disabilities in India. Two hundred fifty-nine children were included and data were collected from the parents. In children with developmental disabilities (excluding autism spectrum diso...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073812447685

    authors: Jain R,Juneja M,Sairam S

    更新日期:2013-04-01 00:00:00

  • Leukoencephalopathy, megalencephaly, and mild clinical course. A recently individualized familial leukodystrophy. Report on five new cases.

    abstract::Five children presented in the first months of life with progressive megalencephaly and leukodystrophy characterized by diffuse swelling of the white matter, cystic cavitations in frontal and temporal lobes, and a slow progressive course contrasting with the intensity of the leukodystrophic process. Four had epilepsy....

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307389601100604

    authors: Goutières F,Boulloche J,Bourgeois M,Aicardi J

    更新日期:1996-11-01 00:00:00

  • Neonate with spinal hypoplasia on T12 and a localized vertebral malformation on L4.

    abstract::We report a case of a neonate with sectional narrowing of the spinal cord on the level of T12 to L2 and a deformed vertebral body on a different level, L4. In previously described cases of sectional spinal dysgenesis, the vertebral and spinal cord malformations are usually found on the same level. Our case may represe...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307380101600819

    authors: Weber A,Maier RF,Felderhoff-Mueser U,Lehmann R,Stöver B,Obladen M

    更新日期:2001-08-01 00:00:00

  • Intravenous immunoglobulin as adjunctive therapy for juvenile spasms.

    abstract::Intravenous immunoglobulin has been reported to be an effective treatment for infantile spasms. Juvenile spasms are electrically and clinically similar to infantile spasms but occur in a later age group. We retrospectively reviewed the charts of five children (aged 4.5-11.5 years) at our institution. Their primary sei...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/08830738030180061001

    authors: Bingel U,Pinter JD,Sotero de Menezes M,Rho JM

    更新日期:2003-06-01 00:00:00

  • Use of corticosteroids in a population-based cohort of boys with duchenne and becker muscular dystrophy.

    abstract::The use of corticosteroids for treatment of Duchenne and Becker muscular dystrophy in clinical practice from 1991 through 2005 was reviewed in a large population-based cohort (MD STARnet) of boys in 4 regional sites and 6 clinics of the United States. Corticosteroid use increased from 20% (11 of 56 individuals) in 199...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073810362762

    authors: Matthews DJ,James KA,Miller LA,Pandya S,Campbell KA,Ciafaloni E,Mathews KD,Miller TM,Cunniff C,Meaney FJ,Druschel CM,Romitti PA,Fox DJ,MD STARnet.

    更新日期:2010-11-01 00:00:00

  • Athletic participation after acute ischemic childhood stroke: a survey of pediatric stroke experts.

    abstract::Minimal evidence exists about the risk of recurrent childhood acute ischemic stroke in patients subjected to a subsequent head or neck injury. Recurrent or multiple dissections have been demonstrated in select cases. Minor head trauma has also been associated with acute ischemic stroke. The objective of this study was...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073807306271

    authors: Bernard TJ,deVeber GA,Benke TA

    更新日期:2007-08-01 00:00:00

  • Central nervous system Sjögren's syndrome in a child: case report and review of the literature.

    abstract::We describe a case of pediatric Sjögren's syndrome with progressive neurologic involvement. At age 4 years, she had been diagnosed with Melkersson-Rosenthal syndrome. After being stable with facial diplegia and swelling for 5 years, she acutely presented with diplopia, vertigo, and ataxia. Cranial magnetic resonance i...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307380101600911

    authors: Gottfried JA,Finkel TH,Hunter JV,Carpentieri DF,Finkel RS

    更新日期:2001-09-01 00:00:00

  • Pyridoxine-dependent seizures caused by alpha amino adipic semialdehyde dehydrogenase deficiency: the first polish case with confirmed biochemical and molecular pathology.

    abstract::Pyridoxine-dependent seizures are a rare condition recognized when numerous seizures respond to pyridoxine treatment and recur on pyridoxine withdrawal. For decades the diagnosis was confirmed only with pyridoxine treatment withdrawal trial. Recently described biochemical and molecular pathology improved the diagnosti...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073808318543

    authors: Kaczorowska M,Kmiec T,Jakobs C,Kacinski M,Kroczka S,Salomons GS,Struys EA,Jozwiak S

    更新日期:2008-12-01 00:00:00

  • Neuro-Behçet disease presenting with acute psychosis in an adolescent.

    abstract::Behçet disease is a systemic vasculitis of unknown etiology that can affect the neurologic system. Neuro-Behçet disease is not well defined in children and adolescents, and the diagnosis is difficult to make in this population as they often present with insufficient symptoms to meet diagnostic criteria. Psychiatric sy...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073813504137

    authors: Patel P,Steinschneider M,Boneparth A,Lantos G

    更新日期:2014-09-01 00:00:00

  • Epidemiology of childhood Guillain-Barré syndrome as a cause of acute flaccid paralysis in Honduras: 1989-1999.

    abstract::The objective of this study was to investigate the incidence of acute flaccid paralysis in the pediatric population of Honduras over an 11-year period, determine what percentage of acute flaccid paralysis was Guillain-Barré syndrome, and identify the epidemiologic features of Guillain-Barré syndrome. There were 546 ch...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/08830738030180110801

    authors: Molinero MR,Varon D,Holden KR,Sladky JT,Molina IB,Cleaves F

    更新日期:2003-11-01 00:00:00

  • Are the pupils of premature infants affected by intraventricular hemorrhage?

    abstract::The size and reactivity to light of the pupil in infants with intraventricular hemorrhage has been variously described in the literature. These descriptions have included miosis, reactivity to light, nonreactivity to light, and anisocoria. We studied the size and light reactivity of 20 infants with intraventricular he...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307389400900423

    authors: Isenberg SJ,Vazquez M

    更新日期:1994-10-01 00:00:00

  • Mumps virus-associated acute encephalopathy: case report and review of the literature.

    abstract::We describe a fatal case of mumps virus-associated acute encephalopathy. In terms of the clinical course and cytokine as well as chemokine profiles, the pathogenesis in our case was different from that of mumps meningoencephalitis but was similar to that of influenza virus-associated acute encephalopathy. ...

    journal_title:Journal of child neurology

    pub_type: 杂志文章,评审

    doi:10.1177/0883073812441060

    authors: Watanabe M,Suyama K,Hashimoto K,Sato M,Ohara S,Abe Y,Kawasaki Y,Yamaguchi S,Saijo M,Hosoya M

    更新日期:2013-02-01 00:00:00

  • The Oklahoma City bombing: a personal account.

    abstract::On April 19, 1995, Oklahoma City (and the United States) lost its innocence. Almost all Oklahomans can relate exactly what they were doing either at 9:02 AM that day or when they first learned of the bombing. Of course, the whole world watched the events unfold through around-the-clock television coverage. One of the ...

    journal_title:Journal of child neurology

    pub_type: 传,历史文章,杂志文章

    doi:10.1177/088307389501000510

    authors: Spengler C

    更新日期:1995-09-01 00:00:00

  • Event-related potentials (P300) in primary headache in childhood and adolescence.

    abstract::There is strong evidence for a loss of habituation during cognitive processing in migraine as measured by P300 and contingent negative variation in adults. Event-related potentials evoked by an oddball paradigm have not yet been studied in children and adolescents suffering from different primary headache types. We re...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307389801300703

    authors: Evers S,Bauer B,Grotemeyer KH,Kurlemann G,Husstedt IW

    更新日期:1998-07-01 00:00:00

  • Experimental models of epilepsy in young animals.

    abstract::Seizures occur more frequently early in life. Some of these early seizures may eventually become epilepsy. Others are reactive seizures due to excessive environmental stimuli that, in any other age group, might not have elicited a similar response. To understand the developmental aspects of seizures and epilepsy in hu...

    journal_title:Journal of child neurology

    pub_type: 杂志文章,评审

    doi:10.1177/0883073894009001031

    authors: Kubová H,Moshé SL

    更新日期:1994-10-01 00:00:00

  • Juvenile dermatomyositis presenting with anasarca.

    abstract::Generalized edema can occur during the course of juvenile dermatomyositis. In this article, a 4-year-old boy with generalized nonpitting edema and proximal weakness is reported. Characteristic cutaneous lesions, laboratory tests, results of electromyography, and magnetic resonance imaging findings resulted in a diagno...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073808318544

    authors: Saygi S,Alehan F,Baskin E,Bayrakci US,Ulu EM,Ozbek N

    更新日期:2008-11-01 00:00:00

  • Brainstem cavernoma hemorrhage during pregnancy in a 15-year-old: description of a unique neurosurgical approach.

    abstract::Cavernous haemangiomas, or cavernous malformations, have been reported during pregnancy, most of which have been either supratentorial or spinal lesions. We encountered a 15-year old pregnant patient with a rapidly progressive and haemorrhagic brainstem cavernous haemangioma. The case presented here describes the hist...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/0883073812457459

    authors: Ranger AM,Chaudhary N,Avery M,Lownie S

    更新日期:2013-10-01 00:00:00

  • Factors predictive of outcome in childhood epilepsy.

    abstract::To identify early predictive factors of outcome in childhood epilepsy, the case records of all children with new-onset epilepsy presenting to a single neurology practice over a 10-year interval were reviewed. Only children with more than 2 years of follow-up were included. Cox regression analysis was used to identify ...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/08830738050200110701

    authors: Oskoui M,Webster RI,Zhang X,Shevell MI

    更新日期:2005-11-01 00:00:00

  • Olfactory Development, Part 1: Function, From Fetal Perception to Adult Wine-Tasting.

    abstract::Discrimination of odorous molecules in amniotic fluid occur after 30 weeks' gestation; fetuses exhibit differential responses to maternal diet. Olfactory reflexes enable reliable neonatal testing. Olfactory bulbs can be demonstrated reliably by MRI after 30 weeks' gestation, and their hypoplasia or aplasia also docume...

    journal_title:Journal of child neurology

    pub_type: 杂志文章,评审

    doi:10.1177/0883073817690867

    authors: Sarnat HB,Flores-Sarnat L,Wei XC

    更新日期:2017-05-01 00:00:00

  • Anencephaly in the United States, 1968-1987: the declining incidence among white infants.

    abstract::The ethical issues concerning the use of fetal tissue as a source for organ transplantation has focused interest on anencephaly. For reasons that are not entirely clear, the incidence of anencephaly has been declining. As anencephaly is easily recognized and invariably fatal, mortality figures provide an excellent ref...

    journal_title:Journal of child neurology

    pub_type: 杂志文章

    doi:10.1177/088307389100600403

    authors: Snyder RD,Fakadej AF,Riggs JE

    更新日期:1991-10-01 00:00:00