Abstract：
:The standard physical examination evaluation for a proprioception abnormality depends upon the patient's ability to follow directions and respond to the examiner, a skill not yet developed in toddlers. This study demonstrates a new proprioception examination method that may allow for better localization of lesions and determines whether healthy toddlers would cooperate with this test. By placing stickers on children's hands, covering their eyes, and then moving their hands, the examiner can see whether the children reach for where their hands and stickers were previously located or to their new location, which serves as an indicator of proprioception ability. When tested on 12- to 36-month-old children without known neurologic issues, we found that older children were more cooperative during the test but that the ability to successfully find the sticker did not depend on age. We have optimized the test for efficient usage in a clinic setting and propose that this is a useful test that can be applied in children, with no change in confidence based on age. No children with known deficits in proprioception were tested, so sensitivity could not be assessed.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Gray EM,Tomlison KG,Kileny S,Leber SMdoi
10.1177/0883073818812348subject
Has Abstractpub_date
2019-03-01 00:00:00pages
128-131issue
3eissn
0883-0738issn
1708-8283journal_volume
34pub_type
杂志文章abstract：:Clinical and subclinical seizures occur frequently among children with autistic spectrum disorders. Electrographic status epilepticus in sleep, or continuous spike-wave in slow-wave sleep, is a typical feature of acquired epileptic aphasia and Landau-Kleffner syndrome. Seizures and epilepsy are more common among child...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/088307380401900106
更新日期：2004-08-01 00:00:00
abstract：:Hypertensive encephalopathy is an uncommon but recognized complication of malignant hypertension in children. We reviewed the clinical course, laboratory studies, and outcomes of 12 patients with hypertensive encephalopathy seen at the University of Iowa Hospitals and Clinics between 1979 and 1994. The most common pre...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307389601100305
更新日期：1996-05-01 00:00:00
abstract：:High-functioning adolescents and young adults with mitochondrial disease are now attempting transitions to postsecondary environments. This pilot and case study explores factors that interfere with their successful transition through behavior-rating scales addressing academic skills and behavior. In the Behavior Asses...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073812442589
更新日期：2012-12-01 00:00:00
abstract：:Amyotrophic lateral sclerosis is a fatal neurodegenerative disease. Epidemiologic data suggest that malnutrition is a common feature in amyotrophic lateral sclerosis and being overweight or obese confers a survival advantage in this patient population. In amyotrophic lateral sclerosis mouse models, a high-fat diet has...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073813488669
更新日期：2013-08-01 00:00:00
abstract：:Pediatric headache patients often experience significant sleep disturbance, which may be a risk factor for poor physical, academic, and emotional functioning, including increased anxiety/fear. The current retrospective cohort study of a clinical sample of youth with persistent headache aimed to examine the impact of s...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073819887597
更新日期：2020-03-01 00:00:00
abstract：:Our current purpose is to evaluate the applicability of dynamic statistical parametric mapping, a novel method for localizing epileptiform activity recorded with magnetoencephalography in patients with epilepsy. We report four pediatric patients with focal epilepsies. Magnetoencephalographic data were collected with a...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738050200041601
更新日期：2005-04-01 00:00:00
abstract：:Cochlear implantation has altered the life-course of thousands of children who have significant hearing loss. Since the United States Food and Drug Administration approved multichannel cochlear implants for children in 1989, growing numbers of parents are choosing this option for their offspring and seeking opportunit...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073812442590
更新日期：2012-06-01 00:00:00
abstract：:A 2-year-old boy with an initial diagnosis of Hunter syndrome (mucopolysaccharidosis II) had a more severe phenotype than expected, which warranted further evaluation. The patient had severe infantile global neurodevelopmental delays, macrocephaly with a prominent forehead, coarse facial features with clear corneas, c...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073811425860
更新日期：2012-06-01 00:00:00
abstract：:Neurocysticercosis is a common parasitic infection of the central nervous system. Intraparenchymal giant cysticercosis has been described in literature, but this is a rare report of a thalamic giant cysticercosis in a young child where the diagnosis could be made on follow-up. A 1½-year-old male child presented with s...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073813513332
更新日期：2014-11-01 00:00:00
abstract：:The acquisition of reading is a complex neurobiologic process. Identifying the most effective instruction and remedial intervention methods for children at risk of developing reading problems and for those who are already struggling is equally complex. This article aims to provide the clinician with a review of more c...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/08830738040190100401
更新日期：2004-10-01 00:00:00
abstract：:Baclofen is widely used to control spasticity in children with cerebral palsy. Several publications described clinical adverse effects of baclofen oral treatment, but the effect of baclofen on seizure potentiation is still controversial. We describe a 10-year-old female patient with cerebral palsy, epilepsy, and menta...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073809357243
更新日期：2010-10-01 00:00:00
abstract：:Acute disseminated encephalomyelitis in children is not uncommon in developing countries, yet there is little systematic documentation of its clinical profile and follow-up. We studied the clinical and neuroradiologic features of acute disseminated encephalomyelitis in 52 consecutive children. Clinical details, magnet...
journal_title：Journal of child neurology
pub_type： 临床试验,杂志文章
doi：10.1177/08830738060210100201
更新日期：2006-10-01 00:00:00
abstract：:Cortical dysplasia is now recognized as one of the major etiologies causing intractable epilepsy in childhood. Dysplastic cortex displays cortical dyslamination, which is often associated with dysmorphic large neurons and less frequently with balloon cells. The dysmorphic large neurons are commonly located in the subc...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/08830738050200040601
更新日期：2005-04-01 00:00:00
abstract：:We report 10 years' follow-up of the previously described family with a novel mutation of the KCNA1 gene. The family consisted of 3 affected boys (first seen at ages 3, 11, and 12) and their affected mother and asymptomatic father and sister. They clinically presented with diffuse myokymia, muscle cramps, and lower li...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073812457461
更新日期：2013-11-01 00:00:00
abstract：:Acute focal neurologic deficits are a rare but known presentation of ornithine transcarbamylase deficiency, particularly in females. We describe here a 6-year-old girl with newly diagnosed ornithine transcarbamylase deficiency who presents with an episode of acute cortical blindness lasting for 72 hours in the absence...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073814535490
更新日期：2015-05-01 00:00:00
abstract：:Girls with Rett syndrome display signs of neuronal dysfunction including mental retardation, seizures, stereotyped movements, and abnormal breathing and autonomic control. Decelerating head growth during infancy might reflect a disorder in production or pruning of neuronal synapses or both. Recent immunocytochemical s...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/08830738030180100501
更新日期：2003-10-01 00:00:00
abstract：:The sphenoid sinus is often referred to as the "neglected sinus." Isolated sphenoid sinusitis is a rare disease with potentially devastating complications. It occurs at an incidence of about 2.7% of all sinus infections. Although headache is the most common presenting symptom, there is no typical headache pattern. Thr...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307380101601203
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:The objectives were to investigate the relationship between ketogenic diet therapy and neutropenia in children with epilepsy. METHODS:A retrospective chart review of children who initiated ketogenic diet at the Hospital for Sick Children between January 1, 2000, and May 1, 2018 was performed. Factors associ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073820984067
更新日期：2021-01-04 00:00:00
abstract：:In this article, we describe a 14-year-old boy with a confirmed diagnosis of Friedreich ataxia who underwent cardiac transplantation for left ventricular failure secondary to dilated cardiomyopathy with restrictive physiology. His neurological status prior to transplantation reflected early signs of neurological disea...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/0883073812448229
更新日期：2012-09-01 00:00:00
abstract：INTRODUCTION:Since its creation, patients on ketogenic diet are told to avoid liquid medications due to theoretical concerns of "hidden" carbohydrates. However, switching from liquid to tablet formulations can be problematic, especially for infants and young children. We theorized that increasing the daily ketogenic ra...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073819831179
更新日期：2019-06-01 00:00:00
abstract：:Metachromatic leukodystrophy is a rare disorder of myelin metabolism. This degenerative disorder results from the accumulation of cerebroside sulfatide within the myelin sheath of central and peripheral nervous system, due to deficiency of aryl sulfatase A enzyme. We report a 5-year-old male child, who presented with ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073814542948
更新日期：2015-03-01 00:00:00
abstract：:The relationship between somatic growth and neurocognitive outcome was studied in a cohort of 136 children with intrauterine growth retardation. The children were followed up from birth to 9 to 10 years of age by annual measurements of growth parameters, neurodevelopmental evaluations, and IQ. The rate of catch-up for...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073808331082
更新日期：2009-07-01 00:00:00
abstract：:Solitary tumefactive demyelination is rare in children, and the diagnosis is often conferred after brain biopsy. The authors report 3 children with solitary tumefactive demyelination and provide clinical and paraclinical clues to aid the clinician in reaching a diagnosis using a noninvasive approach. ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073811401402
更新日期：2011-08-01 00:00:00
abstract：:In industrialized nations with widespread immunization programs, Guillain-Barré syndrome is the most common cause of acute paralytic illness in children and adults. The incidence of the disease has been estimated to range from 0.5 to 1.5 in 100,000 in individuals less than 18 years of age. Approximately 15% of childre...
journal_title：Journal of child neurology
pub_type：
doi：
更新日期：2004-03-01 00:00:00
abstract：:It was recently postulated that because increased genetic load and increased parental age are both purportedly associated with the risk to develop an autism spectrum disorder, there must be a linkage between increasing genetic load and increasing parental age in autism spectrum disorder pathogenesis. The present study...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073814541478
更新日期：2014-08-27 00:00:00
abstract：BACKGROUND:The classic phenotype of CLN2 disease (neuronal ceroid lipofuscinosis type 2) typically manifests between ages 2 and 4 years with a predictable clinical course marked by epilepsy, language developmental delay, and rapid psychomotor decline. Atypical phenotypes exhibit variable time of onset, symptomatology, ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073820977997
更新日期：2020-12-23 00:00:00
abstract：:Development of acylcarnitine and amino acid profiling using tandem mass spectrometry, and its application for use with dried blood specimens collected on filter-paper cards, has introduced an innovative new technology for detecting inborn errors of fatty acid, organic acid, and amino acid metabolism. From November 1, ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073899014001021
更新日期：1999-11-01 00:00:00
abstract：:Five children presented in the first months of life with progressive megalencephaly and leukodystrophy characterized by diffuse swelling of the white matter, cystic cavitations in frontal and temporal lobes, and a slow progressive course contrasting with the intensity of the leukodystrophic process. Four had epilepsy....
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307389601100604
更新日期：1996-11-01 00:00:00
abstract：AIM:We characterize the pediatric postural orthostatic tachycardia syndrome (POTS) population seen at a single tertiary care referral center. METHOD:Retrospective chart review of all pediatric POTS patients seen in our center between 2015 and 2017. Pediatric POTS was defined as chronic, at least 3 months, symptoms of ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073820916260
更新日期：2020-07-01 00:00:00
abstract：:This investigation correlated incidence and degree of autonomic dysfunction with the degree of motor impairment in children hospitalized with Guillain-Barré syndrome. Motor weakness varies, as does the effect on autonomic function including heart rate, vasomotor stability, sweating, continence, and blood pressure. Aft...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073811420872
更新日期：2012-05-01 00:00:00
