Mycotoxins and fermentation--beer production.

Abstract:

:Along with food safety issues due to mycotoxins, the effects of Fusarium infections on malt and beer quality can be disastrous. While some of the Fusarium head blight mycotoxins, such as DON, present in infected barley may be lost during steeping, the Fusarium mold is still capable of growth and mycotoxin production during steeping, germination and kilning. Therefore, detoxification of grain before malting may not be practical unless further growth of the mold is also prevented. Methods for reducing the amount of mold growth during malting are needed. Physical, chemical and biological methods exist for inhibiting mold growth in grain. Irradiation is a promising means for preventing Fusarium growth during malting, but its effects on malt quality and mycotoxin production in surviving mold need to be evaluated in more detail. Chemical treatments such as ozonation, which do not leave chemical residues in beer, also appear to be promising. Although biological control methods may be desirable, the effects of these inhibitors on malt and beer quality require further investigation. In addition, storage studies are needed to determine the effect of biological control on Fusarium viability and malt quality. It may also be possible to incorporate detoxifying genes into fermentation yeasts, which would result in detoxification of mycotoxins present in wort. Development of these types of technological interventions should help improve the safety of products, such as beer, made from Fusarium infected grain.

journal_name

Adv Exp Med Biol

authors

Wolf-Hall CE,Schwarz PB

doi

10.1007/978-1-4615-0629-4_22

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

217-26

eissn

0065-2598

issn

2214-8019

journal_volume

504

pub_type

杂志文章,评审
  • Regulation of Interleukin-10 Expression.

    abstract::Interleukin (IL)-10 is an essential anti-inflammatory cytokine that plays important roles as a negative regulator of immune responses to microbial antigens. Loss of IL-10 results in the spontaneous development of inflammatory bowel disease as a consequence of an excessive immune response to the gut microbiota. IL-10 a...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-94-024-0921-5_5

    authors: Rutz S,Ouyang W

    更新日期:2016-01-01 00:00:00

  • Investigation of the Role of a Supplementation with Taurine on the Effects of Hypoglycemic-Hypotensive Therapy Against Diabetes-Induced Nephrotoxicity in Rats.

    abstract::This study has examined the role of supplementing a treatment of diabetic rats with captopril (CAP), metformin (MET) or CAP-MET with the antioxidant amino acid taurine (TAU) on biochemical indices of diabetes-induced metabolic changes, oxidative stress and nephropathy. To this end, groups of 6 male Sprague-Dawley rats...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-94-024-1079-2_32

    authors: Pandya K,Clark GJ,Lau-Cam CA

    更新日期:2017-01-01 00:00:00

  • Biologically variable respiration as a stochastic process in ventilation - a stochastic model study.

    abstract::Based on the fractal bronchial tree, we introduced a function of "asynchronous phasic contractions of lobular bronchiole", which would generate fluctuations in tidal volumes. Stochastic control theory was able to describe a genesis of biological variability in spontaneous respirations using a Schroedinger wave functio...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4419-5692-7_11

    authors: Min K,Hosoi K,Degami M,Kinoshita Y

    更新日期:2010-01-01 00:00:00

  • Toward a theory of multilevel evolution: long-term information integration shapes the mutational landscape and enhances evolvability.

    abstract::Most of evolutionary theory has abstracted away from how information is coded in the genome and how this information is transformed into traits on which selection takes place. While in the earliest stages of biological evolution, in the RNA world, the mapping from the genotype into function was largely predefined by t...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-3567-9_10

    authors: Hogeweg P

    更新日期:2012-01-01 00:00:00

  • Animal Models of Machado-Joseph Disease.

    abstract::Animal models are an important tool to study the pathophysiology of Machado-Joseph Disease (MJD). So far, animal models using simple organisms (like the round worm Caenorhabditis elegans or the fruit fly drosophila) but also mammalian models (mouse and even a non-human primate model) have been generated to study MJD. ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-71779-1_15

    authors: Schmidt J,Schmidt T

    更新日期:2018-01-01 00:00:00

  • Intracellular signaling in vascular smooth muscle.

    abstract::The two major modalities of pharmacomechanical coupling, inositol 1,4,5, trisphosphate induced Ca2+ release and modulation of Ca(2+)-sensitivity, are reviewed. Recent studies show that although changes in cytoplasmic Ca2+ play the major role in regulating smooth muscle contraction, agonists can also significantly affe...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-2946-0_4

    authors: Somlyo AV,Somlyo AP

    更新日期:1993-01-01 00:00:00

  • Exploitation of Non-mammalian Model Organisms in Epigenetic Research.

    abstract::Model organisms are widely used in research that is ultimately aimed at understanding the causes and consequences of human disease. It may seem counterintuitive to expect clinically useful information to be obtained from species as diverse as fishes and insects, but because fundamental biological mechanisms share evol...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-62414-3_9

    authors: Holt WV

    更新日期:2017-01-01 00:00:00

  • Circannual rhythms in progesterone receptor levels and functions.

    abstract::Studies in this laboratory on the nuclear binding sites (acceptors) for progesterone receptor in the developed chick oviduct have resulted in the detection of seasonal variations in the levels and functions of the receptor. Cytosol preparations obtained from the chick oviducts during the winter/spring period between J...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-6589-2_13

    authors: Spelsberg TC,Boyd PA,Halberg F

    更新日期:1979-01-01 00:00:00

  • The molecular biology and pathophysiology of hypertrophic cardiomyopathy due to mutations in the beta myosin heavy chains and the essential and regulatory light chains.

    abstract::Hypertrophic cardiomyopathy (HCM) is perhaps the most common cause of inherited sudden death in otherwise healthy young individuals. There are presently seven known genes in which mutations have been shown to cause the disease. The first identified disease gene was beta myosin heavy chain (BMHC). Our laboratory has id...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-6039-1_13

    authors: Epstein ND

    更新日期:1998-01-01 00:00:00

  • Computed conformational analysis of lipoxins and their ionic complexes.

    abstract::The possible molecular conformations of four structurally and biologically different lipoxins derivatives were predicted by a systematic structure tree theoretical analysis. This method takes into account the London-Van der Waals energy of interaction, the electrostatic interaction, the rotation energy of the torsiona...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-0937-7_8

    authors: Brasseur R,Serhan CN,Deleers M

    更新日期:1988-01-01 00:00:00

  • Effect of acute ethanol loading on parathyroid gland secretion in the rat.

    abstract::Acute ethanol loading in the rat induces hypocalcemia and hypermagnesemia. In addition, hypocalcemia is not corrected by exogenous PTH. In the rat the mechanism of these changes was investigated by measuring plasma immunoreactive parathyroid hormone (PTH). PTH was also measured in culture medium in which parathyroid g...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-9167-2_54

    authors: Chanard J,Lacour B,Drüeke T,Brunois JP,Ruiz JC

    更新日期:1980-01-01 00:00:00

  • Intramolecular ADP-ribose transfer reactions and calcium signalling. Potential role of 2'-phospho-cyclic ADP-ribose in oxidative stress.

    abstract::Intramolecular ADP-ribose transfer reactions result in the formation of cyclic ADP-ribose (cADPR) and 2'-phospho-cyclic ADP-ribose (P-cADPR) from NAD and NADP, respectively. The potent Ca2+ releasing activity of these cyclic nucleotides has led to the postulation that they function as second messengers of Ca2+ signall...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:

    authors: Vu CQ,Coyle DL,Tai HH,Jacobson EL,Jacobson MK

    更新日期:1997-01-01 00:00:00

  • Single-molecule studies of viral DNA packaging.

    abstract::Many double-stranded DNA bacteriophages and viruses use specialized ATP-driven molecular machines to package their genomes into tightly confined procapsid shells. Over the last decade, single-molecule approaches - and in particular, optical tweezers - have made key contributions to our understanding of this remarkable...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4614-0980-9_24

    authors: Chemla YR,Smith DE

    更新日期:2012-01-01 00:00:00

  • Introduction of new crosslinks into proteins.

    abstract::Analysis of the crosslinks epsilon-(gamma-glutamyl) lysine and epsilon- (beta-aspartyl) lysine present in treated wool has been improved by modifying the enzymic digestion. Treatment of wool with either monocarboxylic acid chlorides in dimethylsulfoxide or with 1-fluoro-2,4-dinitrobenzene in the presence of acetate co...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-3282-4_21

    authors: Ziegler K,Schmitz I,Zahn H

    更新日期:1977-01-01 00:00:00

  • Estrogens and Body Weight Regulation in Men.

    abstract::Our understanding of the metabolic roles of sex steroids in men has evolved substantially over recent decades. Whereas testosterone once was believed to contribute to metabolic risk in men, the importance of adequate androgen exposure for the maintenance of metabolic health has been demonstrated unequivocally. A growi...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-70178-3_14

    authors: Rubinow KB

    更新日期:2017-01-01 00:00:00

  • Antiendothelial cells antibodies in patients with systemic sclerosis in relation to pulmonary hypertension and lung fibrosis.

    abstract::Although scleroderma is generally considered a fibrosing disease, it is now recognized that the underlying vascular pathology is playing a fundamental role in its pathogenesis. The present study was aimed at testing the prevalence of anti-endothelial cell antibodies (AECA) in systemic scleroderma (SSc) patients with a...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-94-007-4549-0_19

    authors: Lewandowska K,Ciurzynski M,Gorska E,Bienias P,Irzyk K,Siwicka M,Zycinska K,Pruszczyk P,Demkow U

    更新日期:2013-01-01 00:00:00

  • Variation in virulence in the gnotobiotic pig model of O157:H7 Escherichia coli strains of bovine and human origin.

    abstract::Escherichia coli strains of serotype O157:H7 have been incriminated in outbreaks and sporadic cases of food-borne illness, including diarrhea, hemorrhagic colitis, hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Food-producing animals, particularly cattle, are believed to be reservoirs of the organi...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4899-1828-4_6

    authors: Baker DR,Moxley RA,Francis DH

    更新日期:1997-01-01 00:00:00

  • Blood-brain barrier drug targeting enables neuroprotection in brain ischemia following delayed intravenous administration of neurotrophins.

    abstract::The blood-brain barrier (BBB) is the rate-limiting step in the translation of neurotrophin neuroscience into clinically effective neurotherapeutics. Since neurotrophins do not cross the BBB, these proteins cannot be used for neuroprotection following intravenous administration, and it is not feasible to administer the...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-0123-7_15

    authors: Pardridge WM

    更新日期:2002-01-01 00:00:00

  • Translational medicine--a paradigm shift in modern drug discovery and development: the role of biomarkers.

    abstract::The success rate of novel medical entities that are submitted for registration by the regulatory agencies and followed successful marketing has been stagnating for the past decade. Failure in efficacy and safety continue to be the prime hurdles and causes of failure. Translational medicine is a new function within the...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4419-1132-2_1

    authors: Day M,Rutkowski JL,Feuerstein GZ

    更新日期:2009-01-01 00:00:00

  • Economic Burden of Clostridium difficile Infection in European Countries.

    abstract::Clostridium difficile infection (CDI) remains a considerable challenge to health care systems worldwide. Although CDI represents a significant burden on healthcare systems in Europe, few studies have attempted to estimate the consumption of resources associated with CDI in Europe. The reported extra costs attributable...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-72799-8_1

    authors: Reigadas Ramírez E,Bouza ES

    更新日期:2018-01-01 00:00:00

  • Biobanks and Their Clinical Application and Informatics Challenges.

    abstract::Biobanks are one of the most important biomedical research resources and contribute to the development of biomarker detection, molecular diagnosis, translational medicine, and multidisciplinary disease research, as well as studies of interactions between genetic and environmental or lifestyle factors. Aiming for the w...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-981-10-1503-8_10

    authors: Yang L,Chen Y,Yu C,Shen B

    更新日期:2016-01-01 00:00:00

  • Role of Neuroinflammation in Opioid Tolerance: Translational Evidence from Human-to-Rodent Studies.

    abstract::Opioid analgesics remain the most effective and widely used analgesics for the management of moderate to severe pain, including cancer pain and chronic non-cancer pain. However, the efficacy of long-term opioid analgesics is attenuated by tolerance and/or hyperalgesia after long-term use, preventing adequate pain reli...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-981-13-1756-9_11

    authors: Lin CP,Lu DH

    更新日期:2018-01-01 00:00:00

  • The role of glyoxalase system in renal hypoxia.

    abstract::Methylglyoxal (MG), a highly reactive alpha-oxoaldehyde generated by oxidation of carbohydrate and glycolysis, binds to proteins and forms advanced glycation end products (AGE). MG and MG adducts have been implicated in oxidative stress-related diseases, therefore, MG detoxifying system such as the glyoxalase system (...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4419-1241-1_6

    authors: Inagi R,Kumagai T,Fujita T,Nangaku M

    更新日期:2010-01-01 00:00:00

  • A Monte Carlo analysis of peritoneal antimicrobial pharmacokinetics.

    abstract::Peritoneal dialysis-associated peritonitis (PDAP) can be treated using very different regimens of antimicrobial administration, regimens that result in different pharmacokinetic outcomes and systemic exposure levels. Currently, there is no population-level pharmacokinetic framework germane to the treatment of PDAP. We...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4419-7046-6_40

    authors: Hota S,Crooke P,Hotchkiss J

    更新日期:2011-01-01 00:00:00

  • Studies of human natural killer cytotoxic factor (NKCF): characterization and analysis of its mode of action.

    abstract::Soluble natural killer cytotoxic factors (NKCF) have been detected in the supernatant of normal mouse, rat, and human lymphocytes stimulated in vitro for 1 to 3 days in serum-free medium. Stimulation of large granular lymphocytes (LGL) with NK-sensitive targets or mitogens has resulted in high levels of NKCF productio...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-8326-0_14

    authors: Ortaldo JR,Blanca I,Herberman RB

    更新日期:1985-01-01 00:00:00

  • Regulation of proteinase inhibitor genes in food plants.

    abstract::Proteinase inhibitor proteins in the families Solanaceae, Leguminosae and Graminae are stored in seeds and tubers and are also found to accumulate in leaves in response to pest attacks. The isolation of the proteinase Inhibitor I cDNA and its gene from tomato has provided information concerning proteinase inhibitor sy...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-0022-0_17

    authors: Brown WE,Graham JS,Lee JS,Ryan CA

    更新日期:1986-01-01 00:00:00

  • Corticospinal transmission after voluntary contractions.

    abstract::Transmastoid stimulation in human subjects evokes a single descending volley in corticospinal axons. Electromyographic (EMG) responses to transmastoid stimuli measured in the relaxed elbow flexor muscles after a maximal voluntary contraction (MVC) are depressed by approximately 50% compared to prior to the MVC. The de...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-0713-0_49

    authors: Taylor JL,Petersen NT,Butler JE,Gandevia S

    更新日期:2002-01-01 00:00:00

  • A method to study induction of autoimmunity in vitro: co-culture of lacrimal cells and autologous immune system cells.

    abstract::Co-culturing autologous lacrimal gland cells and immune system cells can lead to spleen cell proliferation with a time course similar to that for proliferation in a typical heterologous MLR. Although these results are consistent with the hypothesis that lacrimal acinar cells are a source of antigen, and may or may not...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-5359-5_82

    authors: Kaslow HR,Guo Z,Warren DW,Wood RL,Mircheff AK

    更新日期:1998-01-01 00:00:00

  • Oxygen delivery to and use by primary porcine hepatocytes in the HepatAssist 2000 system for extracorporeal treatment of patients in end-stage liver failure.

    abstract::A system for the extracorporeal treatment of end-stage liver failure patients has been developed and is now in clinical studies. This HepatAssist 2000 system consists of perfusing the plasma of the patient through a hollow-fiber bioreactor containing primary porcine hepatocytes. The goal of the system is to assist the...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-4863-8_31

    authors: Custer L,Mullon CJ

    更新日期:1998-01-01 00:00:00

  • Differential response to heat of metastatic and non-metastatic rat mammary tumors.

    abstract::Metastasizing and non-metastasizing transplantable mammary tumors were implanted into female W/Fu rats. A pair of tumors were employed, the SMT-2A and MT-W9B. When these tumors were exposed to water bath heating at 43.5 degrees C for 60 minutes, a significantly longer tumor-free growth delay was obtained in the metast...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-4388-2_15

    authors: Yatvin MB,Vorpahl J,Kim U

    更新日期:1982-01-01 00:00:00