Intestinal expression of apolipoprotein A-IV and C-III is coordinately regulated by dietary lipid in newborn swine.

abstract：:ADAM17 is known to contribute to the immune system through its shedding of tumor necrosis factor alpha (TNFα). However, the role of ADAM17 in B cell biology is not well characterized. To determine whether B cell ADAM17 contributes to T cell-independent humoral immune responses, we crossed CD19 Cre transgenic mice with...

journal_title：Biochemical and biophysical research communications

authors： Lownik JC,Wimberly JL,Takahashi-Ruiz L,Martin RK

更新日期：2020-02-05 00:00:00

abstract：:The reaction of peroxynitrite anion (O=N-OO-) with CO2 results in the formation of an unstable nitrosoperoxycarbonate anion adduct, O=N-OOCO-2 (1). Adduct 1 can serve as a source for several reactive intermediates, including the nitrocarbonate anion (O2N-OCO-2), the carbonate radical ion/nitrogen dioxide radical pair,...

journal_title：Biochemical and biophysical research communications

authors： Uppu RM,Pryor WA

更新日期：1996-12-24 00:00:00

abstract：:Adult height (stature), as an important parameter of human physical development, has been studied in many populations. Recently, we reported a whole genome scan of height on a sample of 630 Caucasian subjects from 53 human pedigrees. Two chromosome regions, 6q24-25 and 7q31.3-36, achieved low linkage signals (multipoi...

journal_title：Biochemical and biophysical research communications

authors： Yang YJ,Liu YZ,Li MX,Lei SF,Chen XD,Sun X,Deng HW

更新日期：2005-10-07 00:00:00

abstract：:The isolation of human adrenal capillary endothelial (HACE) cells without resort to fluorescence activated cell sorting is described, together with their properties in culture. HACE cells were isolated by plating collagenase digests at high dilution in the presence of endothelial cell growth supplement, followed by cl...

journal_title：Biochemical and biophysical research communications

authors： Fawcett J,Harris AL,Bicknell R

更新日期：1991-01-31 00:00:00

abstract：:Clinical attention to gluten-related disorders, such as celiac disease and nonceliac gluten sensitivity, is on the rise. However, identifying the pathophysiological mechanisms of gluten-related disorders remains elusive. Gliadin, a component of gluten, is known to play a major role in gluten toxicity. Caenorhabditis e...

journal_title：Biochemical and biophysical research communications

authors： Lim SD,Min H,Youn E,Kawasaki I,Shim YH

更新日期：2018-09-10 00:00:00

abstract：:A 135kDa DNA polymerase alpha lacking primase activity has been purified to near homogeneity from Coprinus meiotic tissues. The activity of the DNA polymerase was sensitive to aphidicolin and N-ethylmaleimide, but was insensitive to dideoxythymidine triphosphate. DNA synthesis was proceeded with a low processivity. Ne...

journal_title：Biochemical and biophysical research communications

authors： Sawado T,Sakaguchi K

更新日期：1997-03-17 00:00:00

abstract：:Rbx1 and Rbx2 are essential components of Cullin-RING E3 Ligases. Vif is generally believed to preferentially recruit the Cul5-Rbx2 module to induce proteasomal degradation of antiretroviral enzyme APOBEC3G, although some investigators have found that the Cul5-Rbx1 module is recruited. Here, to investigate the functio...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Wang X,Wang W,Zhang J,Wang J,Wang C,Lv M,Zuo T,Liu D,Zhang H,Wu J,Yu B,Kong W,Wu H,Yu X

更新日期：2015-06-12 00:00:00

abstract：:Diphtheria toxin (DT) binds to a specific heparin-binding epidermal growth factor-like growth factor (HB-EGF) precursor that is expressed in DT-sensitive cells. DT binds to the cell-surface HB-EGF precursor with an apparent dissociation constant (KD) of approximately 1 x 10(-8) - 10(-9) M at 4 degreesC, a temperature ...

journal_title：Biochemical and biophysical research communications

authors： Brooke JS,Cha JH,Eidels L

更新日期：1998-07-20 00:00:00

abstract：:Pathogen-triggered generation of reactive oxidants, termed the oxidative burst, contributes to disease resistance in both plant and animal kingdoms. Since phospholipase D plays a key role in the neutrophil oxidative burst signaling cascade and is highly abundant in plants, we investigated its participation in the plan...

journal_title：Biochemical and biophysical research communications

authors： Schroeder Taylor AT,Low PS

更新日期：1997-08-08 00:00:00

abstract：:GALIG, an internal gene to the human galectin-3 gene, encodes two distinct proteins, Mitogaligin and Cytogaligin through translation of a unique mRNA in two overlapping alternative reading frames. When overexpressed GALIG induces apoptosis. In cultured cells, Mitogaligin destabilizes mitochondria membranes through int...

journal_title：Biochemical and biophysical research communications

authors： El Haddad S,Serrano A,Normand T,Robin C,Dubois M,Brulé-Morabito F,Mollet L,Charpentier S,Legrand A

更新日期：2018-01-01 00:00:00

abstract：:A phosphate buffer containing a mixture of glucose oxidase, acrylic acid derivatives, N,N'-1,2 dihydroxy-ethylene-bis(acrylamide), N,N'-(methylene)-bisacrylamide and surface-modified silica was radically polymerized with (NH4)2S2O8. The polymer formed a thin layer around the silica beads. After sieving of these polyme...

journal_title：Biochemical and biophysical research communications

authors： Burow M,Minoura N

更新日期：1996-10-14 00:00:00

abstract：:Cellular uptake of succinylated catalase (Suc-CAT; Mw 227 kDa), bovine serum albumin (Suc-BSA; Mw 70 kDa), superoxide dismutase (Suc-SOD; Mw 34 kDa) and soybean trypsin inhibitor (Suc-STI; Mw 21 kDa) was studied using primary cultures of bovine brain microvessel endothelial cells (BMECs) developed as an in vitro model...

journal_title：Biochemical and biophysical research communications

authors： Tokuda H,Masuda S,Takakura Y,Sezaki H,Hashida M

更新日期：1993-10-15 00:00:00

abstract：:BRAF25 is an alternatively spliced protein of BRAF35 (see associated paper). We have mapped the BRAF25 gene to chromosome sub-band 19p13.3, a region where loss of chromosomal heterozygosity has been reported in about 50% of ovarian cancers. Because of the high incidence of genetic links of prostate cancer to breast an...

journal_title：Biochemical and biophysical research communications

authors： Wang C,McCarty IM,Balazs L,Li Y,Steiner MS

更新日期：2002-07-05 00:00:00

abstract：:The peroxidative activation of the antitumor drugs, etoposide (VP-16) and teniposide (VM-26), has been studied in vitro. Both of these drugs, in the presence of horseradish peroxidase or prostaglandin synthetase, formed phenoxy radical intermediates. Furthermore, this activation also resulted in the formation of two m...

journal_title：Biochemical and biophysical research communications

authors： Haim N,Roman J,Nemec J,Sinha BK

更新日期：1986-02-26 00:00:00

abstract：:Despite the fact that the phosphorylation-mediated regulation of L-type Ca channels is viewed as a model of ion channel regulation, much remains to be learned about the protein phosphorylation and dephosphorylation reactions that underlie the regulation of the channels. The channel isoform most well studied biochemica...

journal_title：Biochemical and biophysical research communications

authors： Zhao XL,Gutierrez LM,Chang CF,Hosey MM

更新日期：1994-01-14 00:00:00

abstract：:We have screened genomic DNA for the identification of D4 dopamine receptor polymorphisms. We show that the D4 dopamine receptor genotype in 72 severely affected chronic alcoholics is heterogeneous, with individuals homozygous and heterozygous for the various D4 receptor alleles. Alcoholics demonstrated a greater prev...

journal_title：Biochemical and biophysical research communications

authors： George SR,Cheng R,Nguyen T,Israel Y,O'Dowd BF

更新日期：1993-10-15 00:00:00

abstract：:Our objective was to determine whether hydroxylamine is a possible intermediate in the oxidative conversion of L-arginine to nitric oxide. Vasorelaxation by hydroxylamine is known to be mediated by nitric oxide. The vasorelaxant properties of hydroxylamine were examined using rat aortic rings and an isolated rat lung ...

journal_title：Biochemical and biophysical research communications

authors： DeMaster EG,Raij L,Archer SL,Weir EK

更新日期：1989-08-30 00:00:00

abstract：:Application of delta-aminolevulinic acid (ALA) results in the endogenous accumulation of protoporphyrin IX and is a useful approach in the photodynamic therapy (PDT) of cancers. To investigate the role of nitric oxide (NO) in the specific accumulation of protoporphyrin and ALA-induced PDT of cancerous cells, we transf...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto F,Ohgari Y,Yamaki N,Kitajima S,Shimokawa O,Matsui H,Taketani S

更新日期：2007-02-16 00:00:00

abstract：:Lysophosphatidic acid (LPA), an extracellular lipid mediator, exerts various cellular effects through activation of LPA receptors, LPA1-LPA6, in many types of cells including cancer cells. We recently found several missense mutations of Lpar1 in rat cancer tissues. One of these mutations is located at the extracellula...

journal_title：Biochemical and biophysical research communications

authors： Ishii S,Tsujiuchi T,Fukushima N

更新日期：2017-05-06 00:00:00

abstract：:The chaperonin containing t-complex polypeptide 1 (CCT) is a heterooligomeric molecular chaperone that assists in the folding of actin, tubulin, and other cytosolic proteins. We show here that degradation of CCT in mammalian cells is inhibited by a proteasome-specific inhibitor, lactacystin. When CCT synthesis was inh...

journal_title：Biochemical and biophysical research communications

authors： Yokota S,Kayano T,Ohta T,Kurimoto M,Yanagi H,Yura T,Kubota H

更新日期：2000-12-20 00:00:00

abstract：:Astrocytic glycogen metabolism sustains neuronal activity but its impact on basal glutamatergic synaptic transmission is not clear. To address this issue, we have compared the effect of glycogen breakdown inhibition on miniature excitatory postsynaptic currents (mEPSCs) in rat hippocampal pure neuronal culture (PNC) a...

journal_title：Biochemical and biophysical research communications

authors： Mozrzymas J,Szczęsny T,Rakus D

更新日期：2011-01-14 00:00:00

abstract：:Expression of ALP in F9 teratocarcinoma cells is induced by all-trans retinoic acid (ATRA) (Gianni' et al., Biochem. J. 274: 673-678, 1991). The specific ligand for retinoic acid related receptors (RXRs), 9-cis retinoic acid (9-cis RA), and three synthetic analogs binding to the alpha, beta and gamma forms of the reti...

journal_title：Biochemical and biophysical research communications

authors： Gianni M,Zanotta S,Terao M,Garattini S,Garattini E

更新日期：1993-10-15 00:00:00

abstract：:Here we enhanced the stability and biophysical properties of mRFP1 through a combination of canonical and non-canonical amino acid mutagenesis. The global replacement of proline residue with (2S, 4R)-4-fluoroproline [(4R)-FP] into mRFP1 led to soluble protein but lost its fluorescence, whereas (2S, 4S)-4-fluoroproline...

journal_title：Biochemical and biophysical research communications

authors： Deepankumar K,Nadarajan SP,Ayyadurai N,Yun H

更新日期：2013-11-01 00:00:00

abstract：:Photoinactivation is a common phenomenon in bioluminescence ctenophore photoproteins (e.g mnemiopsin, berovin and BfosPP) with still unknown mechanism. The activity of coelenterate photoproteins (e.g aequorin), which has high structural similarity with ctenophore photoproteins, is not affected by light. Recently, we h...

journal_title：Biochemical and biophysical research communications

authors： Pashandi Z,Molakarimi M,Mohseni A,Sajedi RH,Taghdir M,Naderi-Manesh H

更新日期：2017-08-19 00:00:00

abstract：:Hemoglobin (Hb) isolated from the backswimmer Buenoa margaritacea has been analyzed spectroscopically. The met form at pH less than 6 shows a 30nm red shift in the Qv and Qo bands and a 5nm red shift in the Soret band compared to mammalian Hb, while only minor differences are seen in the spectra of the CO and O2 adduc...

journal_title：Biochemical and biophysical research communications

authors： Osmulski PA,Vossbrinck CR,Sampath V,Caughey WS,Debrunner PG

更新日期：1992-09-16 00:00:00

abstract：:Adiponectin, an adipocyte-derived hormone, attenuates the production of TNFalpha by activated human macrophages. In the present study, we used porcine blood-derived macrophages to test the hypothesis that the anti-inflammatory action of adiponectin includes suppression of IL6 and an induction of IL10. Adiponectin supp...

journal_title：Biochemical and biophysical research communications

authors： Wulster-Radcliffe MC,Ajuwon KM,Wang J,Christian JA,Spurlock ME

更新日期：2004-04-09 00:00:00

abstract：:To address the role of brain gangliosides in synaptic activity, the ceramide analogs, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP) and its enantiomer, L-PDMP, were used to inhibit and stimulate ganglioside biosynthesis in cultured cortical neurons. Prolonged treatment with both PDMP isomers exhibi...

journal_title：Biochemical and biophysical research communications

authors： Inokuchi J,Mizutani A,Jimbo M,Usuki S,Yamagishi K,Mochizuki H,Muramoto K,Kobayashi K,Kuroda Y,Iwasaki K,Ohgami Y,Fujiwara M

更新日期：1997-08-28 00:00:00

abstract：:Two common non-steroidal anti-inflammatory drugs (NSAIDs) and their nitric oxide (NO) adducts were evaluated for effects on stomach and thymus. Following 4-h duration (acute) oral dosing of fasted male Wistar rats, 1.33 x 10(-4)mol/kg of ibuprofen caused significant visual irritation score and microscopic thinning, al...

journal_title：Biochemical and biophysical research communications

authors： Downing JE,Madden JC,Ingram MJ,Rostron C

更新日期：2005-08-26 00:00:00

abstract：:Low molecular weight-PTP has been reported as a redox-sensitive protein during both platelet-derived growth factor and integrin signalling. In response to oxidation the phosphatase undergoes a reversible inactivation, which in turn leads to the increase in tyrosine phosphorylation of its substrates and the properly ex...

journal_title：Biochemical and biophysical research communications

authors： Giannoni E,Raugei G,Chiarugi P,Ramponi G

更新日期：2006-09-22 00:00:00

abstract：:We established two monoclonal antibodies (mAbs) which specifically recognize human 'functionally inactive' recombinant IL-18, and IL-18 protein polymorphism was examined using human monocytes and macrophages (M phi). In 6 day GM-CSF-treated M phi, an 'inactive' IL-18-recognizing mAb 21 detected the IL-18 proform (24 k...

journal_title：Biochemical and biophysical research communications

authors： Kikkawa S,Matsumoto M,Shida K,Fukumori Y,Toyoshima K,Seya T

更新日期：2001-02-23 00:00:00