Alterations in spectral characteristics of heart rate variability as a correlate of cardiac autonomic dysfunction after esophagectomy or pulmonary resection.

abstract：BACKGROUND:Postoperative nausea and vomiting (PONV) is a commonly observed adverse effect of general anesthesia. Recently, ondansetron, a new serotonin3 (5-hydroxytryptamine3) receptor antagonist was shown to be effective in the prophylaxis and prevention of chemotherapy-induced nausea and vomiting in children and adul...

journal_title：Anesthesiology

authors： Ummenhofer W,Frei FJ,Urwyler A,Kern C,Drewe J

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Management of cardiovascular implantable electronic devices (CIEDs), including pacemakers and implantable cardioverter defibrillators, for surgical procedures is challenging due to the increasing number of patients with CIEDs and limited availability of trained providers. At the authors' institution, a small...

journal_title：Anesthesiology

authors： Rooke GA,Lombaard SA,Van Norman GA,Dziersk J,Natrajan KM,Larson LW,Poole JE

更新日期：2015-11-01 00:00:00

abstract：:Intravenous lidocaine has been shown to relieve acute postoperative pain and chronic neuropathic pain. It is not known whether analgesia produced by 2-10 micrograms/ml plasma concentrations of lidocaine is due to an effect on peripheral-pain-transducing nerves or to central nervous system effects. The current study ex...

journal_title：Anesthesiology

authors： Tanelian DL,MacIver MB

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Aprotinin has been reported to reduce blood loss and transfusion requirements in patients having major orthopedic operations. Data on whether epsilon amino-caproic acid (EACA) is effective in this population are sparse. METHODS:Sixty-nine adults with malignancy scheduled for either pelvic, extremity or spin...

journal_title：Anesthesiology

authors： Amar D,Grant FM,Zhang H,Boland PJ,Leung DH,Healey JA

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Isoflurane-anesthetized rats have better outcome from global cerebral ischemia than rats anesthetized with fentanyl and nitrous oxide. The authors wanted to determine whether circulating catecholamine concentrations depend on the anesthetic agent and whether sympathetic ganglionic blockade affects anesthetic...

journal_title：Anesthesiology

authors： Mackensen GB,Nellgård B,Miura Y,Chu CT,Dexter F,Pearlstein RD,Warner DS

更新日期：1999-03-01 00:00:00

abstract：:To determine if a relationship exists between perioperative myocardial ischemia (ST segment depression greater than or equal to 0.1 mV) and postoperative myocardial infarction (PMI), nonparticipating observers recorded all ECG, hemodynamic, and other events between arrival of patients in the operating room and onset o...

journal_title：Anesthesiology

authors： Slogoff S,Keats AS

更新日期：1985-02-01 00:00:00

abstract：:Recent reports have described resistance to pancuronium-induced neuromuscular blockade in patients chronically receiving anticonvulsants. This study examines the pharmacokinetics and pharmacodynamics of metocurine (MTC) in 12 patients undergoing craniotomy--six on chronic phenytoin therapy and six comparable controls....

journal_title：Anesthesiology

authors： Ornstein E,Matteo RS,Young WL,Diaz J

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:A new endotracheal tube (ETT) was fabricated and tested in sheep. It had no tracheal cuff; airway seal was achieved at the level of the glottis through a no-pressure seal made of "gills"; the laryngeal portion was oval-shaped; and the wall thickness was reduced to 0.2 mm. METHODS:Sheep were tracheally intub...

journal_title：Anesthesiology

authors： Reali-Forster C,Kolobow T,Giacomini M,Hayashi T,Horiba K,Ferrans VJ

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:In the partial CO(2) rebreathing method, monitored changes in CO(2) elimination and end-tidal CO(2) in response to a brief rebreathing period are used to estimate cardiac output. However, dynamic changes in CO(2) production during ischemia and reperfusion may affect the accuracy of these estimates. This stud...

journal_title：Anesthesiology

authors： Kotake Y,Moriyama K,Innami Y,Shimizu H,Ueda T,Morisaki H,Takeda J

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Serious complications related to regional anesthesia have previously been described primarily in case reports and retrospective surveys. The authors prospectively evaluated a multicenter series of regional anesthetics, using preplanned criteria to measure the incidence and characteristics of associated serio...

journal_title：Anesthesiology

authors： Auroy Y,Narchi P,Messiah A,Litt L,Rouvier B,Samii K

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:The general anesthetics, isoflurane and sevoflurane, cause developmental abnormalities in neonatal animal models via incompletely understood mechanisms. Despite many common molecular targets, isoflurane and sevoflurane exhibit substantial differences in their actions. The authors sought to determine whether ...

journal_title：Anesthesiology

authors： Seubert CN,Zhu W,Pavlinec C,Gravenstein N,Martynyuk AE

更新日期：2013-08-01 00:00:00

abstract：:No significant change in pseudocholinesterase levels was observed in random specimens of whole blood stored for as long as 30 days. Levels in plasma anticoagulated with heparin or ethylenediaminetetraacetic acid declined only slightly. Therefore, massive transfusions do not contraindicate succinylcholine administratio...

journal_title：Anesthesiology

authors： Lanks KW,Sklar GS

更新日期：1976-05-01 00:00:00

abstract：:Arterial tonometry is a technique used to measure arterial blood pressure noninvasively. The authors developed a new tonometer system containing an array of 15 piezoresistive pressure transducers, a mechanical positioning system, signal conditioning and multiplexing electronics, and a display and control console. The ...

journal_title：Anesthesiology

authors： Kemmotsu O,Ueda M,Otsuka H,Yamamura T,Winter DC,Eckerle JS

更新日期：1991-08-01 00:00:00

abstract：:The authors evaluated the systemic and cerebral hemodynamic and metabolic effects of 1 h of hypotension to a mean arterial pressure of either 50 mmHg or 40 mmHg induced by intravenous adenosine or ATP in dogs maintained on 70% nitrous oxide and 0.1% halothane. Following the hypotensive period, brain biopsy specimens w...

journal_title：Anesthesiology

authors： Newberg LA,Milde JH,Michenfelder JD

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:The current study was performed to determine whether volatile anesthetics may include as part of their action in the central nervous system the depression of presynaptic transmitter release by alteration in intrasynaptic [Ca2+] ([Ca2+]i). METHODS:Guinea pig cerebrocortical synaptosomes were studied at 37 de...

journal_title：Anesthesiology

authors： Miao N,Frazer MJ,Lynch C 3rd

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:QX-314 produces nociceptive blockade, facilitated by permeation through transient receptor potential vanilloid-1 (TRPV1) channels. TRPV1 channel can be activated by noxious heat and sensitized by volatile anesthetics. The authors hypothesized that emulsified isoflurane (EI) could enhance thermal TRPV1 channe...

journal_title：Anesthesiology

authors： Zhou C,Liang P,Liu J,Zhang W,Liao D,Chen Y,Chen X,Li T

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) is a serious postoperative complication with limited treatment options. A preoperative risk-prediction model would assist clinicians and scientists interested in ALI. The objective of this investigation was to develop a surgical lung injury prediction (SLIP) model to predict risk of p...

journal_title：Anesthesiology

authors： Kor DJ,Warner DO,Alsara A,Fernández-Pérez ER,Malinchoc M,Kashyap R,Li G,Gajic O

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Patients who are homozygous for the atypical mutation, compound heterozygous for atypical and silent mutations, or homozygous for silent mutations (SS) respond to mivacurium with extensively prolonged neuromuscular block. Although important, exact phenotyping of these patients is difficult. This article pres...

journal_title：Anesthesiology

authors： Gätke MR,Ostergaard D,Bundgaard JR,Varin F,Viby-Mogensen J

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Mask ventilation is an essential element of airway management that has rarely been studied as the primary outcome. The authors sought to determine the incidence and predictors of difficult and impossible mask ventilation. METHODS:A four-point scale to grade difficulty in performing mask ventilation (MV) is ...

journal_title：Anesthesiology

authors： Kheterpal S,Han R,Tremper KK,Shanks A,Tait AR,O'Reilly M,Ludwig TA

更新日期：2006-11-01 00:00:00

abstract：:We performed a prospective randomized controlled trial to assess the efficacy of a chlorhexidine dressing in reducing the microbial flora at the insertion site of epidural catheters. These catheters were used for acute pain management and were dressed either by a standardized method or with a CHX/urethane sponge compo...

journal_title：Anesthesiology

authors： Shapiro JM,Bond EL,Garman JK

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:The discrepancy between predicted effect-site concentration and measured bispectral index is problematic during intravenous anesthesia with target-controlled infusion of propofol and remifentanil. We hypothesized that bispectral index during total intravenous anesthesia would be more accurately predicted by ...

journal_title：Anesthesiology

authors： Lee HC,Ryu HG,Chung EJ,Jung CW

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Perioperative thoracic epidural analgesia reduces stress response and pain scores and may improve outcome after cardiac surgery. This prospective, randomized trial was designed to compare the effectiveness of patient-controlled thoracic epidural analgesia with patient-controlled analgesia with intravenous mo...

journal_title：Anesthesiology

authors： Hansdottir V,Philip J,Olsen MF,Eduard C,Houltz E,Ricksten SE

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Ca2+-permeable non-N-methyl-D-aspartate receptors are found in the spinal dorsal horn and represent a presumptive target for glutamatergic transmission in nociceptive processing. This study characterized the analgesic profile associated with the blockade of these spinal receptors by intrathecally delivered a...

journal_title：Anesthesiology

authors： Sorkin LS,Yaksh TL,Doom CM

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:A relatively small number of inhibitory interneurons can control the excitability and synchronization of large numbers of pyramidal cells in hippocampus and other cortical regions. Thus, anesthetic modulation of interneurons could play an important role for the maintenance of anesthesia. The aim of this stud...

journal_title：Anesthesiology

authors： Nishikawa K,MacIver MB

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Long-term neuroprotection by isoflurane has been questioned. The authors examined factors in experimental models potentially critical to definition of enduring isoflurane neuroprotection. METHODS:Rats were prepared for temporary middle cerebral artery occlusion (MCAO). Pericranial normothermia was maintaine...

journal_title：Anesthesiology

authors： Sakai H,Sheng H,Yates RB,Ishida K,Pearlstein RD,Warner DS

更新日期：2007-01-01 00:00:00

abstract：:Cognitive performance in postsurgical patients may be impaired by disturbances of normal circadian rhythm analogous to those produced by rapid transmeridian travel ("jet lag"). We therefore tested the hypothesis that isoflurane anesthesia alone produces a phase-delay in the human circadian temperature rhythm. We monit...

journal_title：Anesthesiology

authors： Sessler DI,Lee KA,McGuire J

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury and often leads to multiorgan dysfunction and systemic inflammation. Volatile anesthetics have potent antiinflammatory effects. We aimed to determine whether the representative volatile anesthetic isoflurane protects against acut...

journal_title：Anesthesiology

authors： Kim M,Park SW,Kim M,D'Agati VD,Lee HT

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Days alive and out of hospital is a potentially useful patient-centered quality measure for perioperative care in adult surgical patients. However, there has been very limited prior validation of this endpoint with respect to its ability to capture differences in patient-level risk factor profiles and longer...

journal_title：Anesthesiology

authors： Jerath A,Austin PC,Wijeysundera DN

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Enflurane and isoflurane are structural isomers with different anesthetic potencies and side effects. It is not clear whether these differences are produced by differing occupancy of common protein binding sites or by occupancy of different sites, but the very similar molecular properties make the latter pos...

journal_title：Anesthesiology

authors： Liu R,Eckenhoff RG

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Ketamine is often administered to patients in whom hemodynamic instability is suspected. This study was designed to investigate the effect and possible site of action of ketamine on baroreflex response in rats. The site focused upon was the N-methyl-D-aspartate (NMDA) receptor of the nucleus tractus solitari...

journal_title：Anesthesiology

authors： Ogawa A,Uemura M,Kataoka Y,Ol K,Inokuchi T

更新日期：1993-01-01 00:00:00