Stability of pseudocholinesterase in stored blood.

abstract：BACKGROUND:Intraoperative remifentanil infusions have been associated with postoperative opioid-induced hyperalgesia and tolerance. Using a previously identified subpopulation of spinal neurons that displays an augmentation in N-methyl-D-aspartate (NMDA) receptor current after chronic morphine, investigations were unde...

journal_title：Anesthesiology

authors： Zhao M,Joo DT

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The authors conducted a randomized controlled trial to determine whether parental presence during induction of anesthesia (PPIA) is associated with parental physiologic and behavioral manifestations of stress. METHODS:Children and their parents (N = 80) were randomly assigned to one of three groups: (1) PPI...

journal_title：Anesthesiology

authors： Kain ZN,Caldwell-Andrews AA,Mayes LC,Wang SM,Krivutza DM,LoDolce ME

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Mechanical ventilation (MV) is a life-saving intervention in patients with acute respiratory failure. However, prolonged MV results in ventilator-induced diaphragm dysfunction (VIDD), a condition characterized by both diaphragm fiber atrophy and contractile dysfunction. Previous work has shown that calpain, ...

journal_title：Anesthesiology

authors： Smuder AJ,Nelson WB,Hudson MB,Kavazis AN,Powers SK

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Surgery causes changes in hemostasis, leading to a hypercoagulable state. This postoperative increase in hemostatic function is attenuated in patients receiving regional anesthesia compared with those receiving general anesthesia. Regional anesthesia also decreases the neuroendocrine response to surgery comp...

journal_title：Anesthesiology

authors： Rosenfeld BA,Faraday N,Campbell D,Dise K,Bell W,Goldschmidt P

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Protein kinase C (PKC) is a family of serine/threonine kinases that contains more than 10 isozymes. Evidence suggests that PKC may play important roles in pain modulation, but the isozyme-specific effects of PKC on different aspects of pain modulation are not fully understood. We hypothesize that different P...

journal_title：Anesthesiology

authors： Zhao C,Leitges M,Gereau RW 4th

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Only limited data exist comparing differences in sensory function and responses to neural blockade in infant and adult rats. Therefore, the authors sought (1) to compare baseline thermal, proprioceptive, and postural responses in infant, adolescent, and adult rats; and (2) to compare the effects of sciatic n...

journal_title：Anesthesiology

authors： Hu D,Hu R,Berde CB

更新日期：1997-04-01 00:00:00

abstract：:This study examined whether pain or stress can enhance the analgesic effects of spinally administered opiates. The experiments determined the effects of mechanically produced pain and of the stress of being restrained on the analgesic effects of 0.63 microgram of epidural sufentanil in rats using a tail-withdrawal pro...

journal_title：Anesthesiology

authors： Van den Hoogen RH,Bervoets K,Colpaert FC

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Neosaxitoxin (NeoSTX) is a site-1 sodium channel blocker that produces prolonged local anesthesia in animals and humans. Under a Food and Drug Administration-approved phase 1 Investigational New Drug trial, the authors evaluated safety and efficacy of NeoSTX alone and combined with 0.2% bupivacaine (Bup) wit...

journal_title：Anesthesiology

authors： Lobo K,Donado C,Cornelissen L,Kim J,Ortiz R,Peake RW,Kellogg M,Alexander ME,Zurakowski D,Kurgansky KE,Peyton J,Bilge A,Boretsky K,McCann ME,Berde CB,Cravero J

更新日期：2015-10-01 00:00:00

abstract：:There is controversy about whether N2O increases cerebral blood flow and cortical oxygen consumption (CMRO2) in rats. Cortical and subcortical blood flow and CMRO2 were measured in awake, unrestrained rats while awake and during 70% N2O administration using radioactive microspheres. In the awake state, cortical and su...

journal_title：Anesthesiology

authors： Baughman VL,Hoffman WE,Miletich DJ,Albrecht RF

更新日期：1990-08-01 00:00:00

abstract：:The pharmacokinetics and protein binding of propofol were studied in ten patients with cirrhosis and in ten control patients undergoing elective surgery. All patients received 2.5 mg.kg-1 propofol as an intravenous bolus injection for the induction of anesthesia. Whole blood propofol concentrations were measured at in...

journal_title：Anesthesiology

authors： Servin F,Desmonts JM,Haberer JP,Cockshott ID,Plummer GF,Farinotti R

更新日期：1988-12-01 00:00:00

abstract：:Hemodynamic changes during four anesthetic techniques were studied in 80 preterm neonates. Atropine, 0.02 mg/kg, and pancuronium, 0.1 mg/kg, were given intravenously to all patients, who were ventilated with oxygen and air. Each group of 20 patients then received 0.75% isoflurane, 0.5% halothane, 20 micrograms/kg fent...

journal_title：Anesthesiology

authors： Friesen RH,Henry DB

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Epidural morphine yields postoperative pain relief and hemodynamic stability. However, the effects of epidural morphine on sympathetic tone are unclear. This study was designed to elucidate the effects of epidural morphine on cardiac (CSNA) and renal (RSNA) sympathetic nerve activity by direct measurement in...

journal_title：Anesthesiology

authors： Mori T,Nishikawa K,Terai T,Yukioka H,Asada A

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:The effects of triiodothyronine (T3) on systemic hemodynamics, myocardial contractility (preload recruitable stroke work slope; Mw), and left ventricular (LV) isovolumic relaxation (time constant; tau) were examined before and after the development of pacing-induced cardiomyopathy in conscious dogs. METHODS...

journal_title：Anesthesiology

authors： Jamall IN,Pagel PS,Hettrick DA,Lowe D,Kersten JR,Tessmer JP,Warltier DC

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Patients undergoing cardiac surgery employing cardiopulmonary bypass frequently require transfusion of homologous blood products and, therefore, are exposed to the risk of transfusions. Autologous platelet-rich plasma administration may reduce homologous transfusion and attendant risks. METHODS:In a blinded...

journal_title：Anesthesiology

authors： Ereth MH,Oliver WC Jr,Beynen FM,Mullany CJ,Orszulak TA,Santrach PJ,Ilstrup DM,Weaver AL,Williamson KR

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Nonimmobilizers are agents that lack anesthetic properties, although their chemical structure is very similar to known anesthetics. The primary action site of both agents, whether at the membrane or target protein level, is still a matter of debate. However, increasing evidence points to the distinct modific...

journal_title：Anesthesiology

authors： Koubi L,Tarek M,Bandyopadhyay S,Klein ML,Scharf D

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:While persistent opioid use after surgery has been the subject of a large number of studies, it is unknown how much variability in the definition of persistent use impacts the reported incidence across studies. The objective was to evaluate the incidence of persistent use estimated with different definitions...

journal_title：Anesthesiology

authors： Jivraj NK,Raghavji F,Bethell J,Wijeysundera DN,Ladha KS,Bateman BT,Neuman MD,Wunsch H

更新日期：2020-06-01 00:00:00

abstract：:The effects of continuous positive airway pressure (CPAP) on cardiovascular dynamics and pulmonary shunt (QS/QT) were investigated in 12 dogs before and during sodium nitroprusside infusion that decreased mean arterial blood pressure 40-50 per cent. Before nitroprusside infusion, 5 cm H2O CPAP significantly, P less th...

journal_title：Anesthesiology

authors： Hodges MR,Stanley TH,Johansen RK

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Available treatments for neuropathic pain have modest efficacy and significant adverse effects, including abuse potential. Because oxidative stress is a key mechanistic node for neuropathic pain, the authors focused on the master regulator of the antioxidant response-nuclear factor erythroid 2-related factor...

journal_title：Anesthesiology

authors： Li J,Ma J,Lacagnina MJ,Lorca S,Odem MA,Walters ET,Kavelaars A,Grace PM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether combination of 1-5 microg intrathecal neostigmine would enhance analgesia from a fixed intrathecal dose of morphine. METHODS:A total of 60 patients undergoing gynecologic surgery were randomized to one of five groups. Patients received 15 mg bupivacaine plu...

journal_title：Anesthesiology

authors： Almeida RA,Lauretti GR,Mattos AL

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Management of cardiovascular implantable electronic devices (CIEDs), including pacemakers and implantable cardioverter defibrillators, for surgical procedures is challenging due to the increasing number of patients with CIEDs and limited availability of trained providers. At the authors' institution, a small...

journal_title：Anesthesiology

authors： Rooke GA,Lombaard SA,Van Norman GA,Dziersk J,Natrajan KM,Larson LW,Poole JE

更新日期：2015-11-01 00:00:00

abstract：:Evidence of developmental toxicity of clinically used nondepolarizing muscle relaxants was sought in rat embryos grown in culture. Embryos were explanted at 8 AM on day 9 of gestation (presomite stage, plug day = day 0), and were cultured in rotating bottles with medium containing various concentrations of d-tubocurar...

journal_title：Anesthesiology

authors： Fujinaga M,Baden JM,Mazze RI

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:We examined the effects of different anesthetics on cerebral oxygenation and systemic hemodynamics in patients undergoing surgery in beach chair position (BCP). Jugular venous bulb oxygen saturation (SjvO2) and regional cerebral tissue oxygen saturation (SctO2) were determined while patients were placed from...

journal_title：Anesthesiology

authors： Jeong H,Jeong S,Lim HJ,Lee J,Yoo KY

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Some patients develop recrudescence after a malignant hyperthermia (MH) reaction, but it is not clear which patients are at risk. The authors analyzed clinical variables associated with recrudescence after a clinical MH episode. METHODS:Data were obtained from Adverse Metabolic Reaction to Anesthesia report...

journal_title：Anesthesiology

authors： Burkman JM,Posner KL,Domino KB

更新日期：2007-05-01 00:00:00

abstract：:In view of evidence suggesting possible participation of cobalamin in cyanide metabolism, the effects of sodium nitroprusside (SNP) infusion on blood cyanide and plasma thiocyanate levels and serum vitamin B12 levels were examined in ten patients undergoing major orthopedic procedures. Whole blood cyanide concentratio...

journal_title：Anesthesiology

authors： Fahmy NR

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Preoperative anemia is frequent in patients undergoing orthopedic surgery. The purpose of this study was to assess the preoperative increase of hemoglobin in iron deficiency anemia patients treated with intravenous iron. METHODS:After obtaining written informed consent, 20 patients with iron deficiency anem...

journal_title：Anesthesiology

authors： Theusinger OM,Leyvraz PF,Schanz U,Seifert B,Spahn DR

更新日期：2007-12-01 00:00:00

abstract：:This study was performed to determine the potency of succinylcholine using the single-dose technique, and to test the ability of the cumulative dose technique for generating dose-response data. Thirty-eight adult patients received single doses (n = 18), cumulative doses (n = 10), or cumulative doses of succinylcholine...

journal_title：Anesthesiology

authors： Smith CE,Donati F,Bevan DR

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Forced-air warming is sometimes unable to maintain perioperative normothermia. Therefore, the authors compared heat transfer, regional heat distribution, and core rewarming of forced-air warming with a novel circulating-water garment. METHODS:Nine volunteers were each evaluated on two randomly ordered study...

journal_title：Anesthesiology

authors： Taguchi A,Ratnaraj J,Kabon B,Sharma N,Lenhardt R,Sessler DI,Kurz A

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Perfluorocarbon (PFC) liquids are known to improve gas exchange and pulmonary function in various models of acute respiratory failure. Vaporization has been recently reported as a new method of delivering PFC to the lung. Our aim was to study the effect of PFC vapor on the ventilation/perfusion (VA/Q) matchi...

journal_title：Anesthesiology

authors： Hübler M,Souders JE,Shade ED,Polissar NL,Schimmel C,Hlastala MP

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:A recent model of acute incisional pain has been characterized that strongly parallels the postoperative period in patients experiencing evoked pain. In that setting, abundant literature has revealed antihypersensitive effects produced by intrathecally administered alpha2-adrenergic receptor agonists, such a...

journal_title：Anesthesiology

authors： Duflo F,Boselli E,Ryvlin P,Chassard D

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The authors sought to understand neural correlates of anesthetic-induced unconsciousness. Cortical gamma oscillations have been associated with neural processes supporting conscious perception, but the effect of general anesthesia on these oscillations is controversial. In this study, the authors examined th...

journal_title：Anesthesiology

authors： Imas OA,Ropella KM,Ward BD,Wood JD,Hudetz AG

更新日期：2005-05-01 00:00:00