Antifibrinolytic therapy and perioperative blood loss in cancer patients undergoing major orthopedic surgery.

abstract：:The present study was designed to determine changes in hepatic oxygen supply in guinea pigs during halothane or isoflurane anesthesia. Twenty-seven guinea pigs were randomly divided into three equal groups: control (no anesthesia) group, and animals anesthetized with halothane or isoflurane to decrease mean arterial p...

journal_title：Anesthesiology

authors： Hursh D,Gelman S,Bradley EL Jr

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:The value of exercise electrocardiography in the prediction of perioperative cardiac risk has yet to be defined. This study was performed to determine the predictive value of exercise electrocardiography as compared with clinical parameters and resting electrocardiography. METHODS:A total of 204 patients at...

journal_title：Anesthesiology

authors： Gauss A,Röhm HJ,Schäuffelen A,Vogel T,Mohl U,Straehle A,Meierhenrich R,Georgieff M,Steinbach G,Schütz W

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In 2001, the Centers for Medicare and Medicaid Services issued a rule allowing U.S. states to "opt out" of the regulations requiring physician supervision of nurse anesthetists in an effort to increase access to anesthesia care. Whether "opt out" has successfully achieved this goal remains unknown. METHODS:...

journal_title：Anesthesiology

authors： Sun EC,Dexter F,Miller TR,Baker LC

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Insufficient data exist on the production of compound A during closed-system sevoflurane administration with newer carbon dioxide absorbents. METHODS:A modified PhysioFlex apparatus (Dräger, Lübeck, Germany) was connected to an artificial test lung (inflow at the top of the bellow approximately/= 160 ml/min...

journal_title：Anesthesiology

authors： Versichelen LF,Bouche MP,Rolly G,Van Bocxlaer JF,Struys MM,De Leenheer AP,Mortier EP

更新日期：2001-09-01 00:00:00

abstract：:This study was performed to determine the potency of succinylcholine using the single-dose technique, and to test the ability of the cumulative dose technique for generating dose-response data. Thirty-eight adult patients received single doses (n = 18), cumulative doses (n = 10), or cumulative doses of succinylcholine...

journal_title：Anesthesiology

authors： Smith CE,Donati F,Bevan DR

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:The long-term use of opioids for analgesia carries significant risk for tolerance, addiction, and diversion. These adverse effects are largely mediated by μ-opioid receptors in the central nervous system. Based on the authors' previous observation that morphine and δ-opioid receptor agonists synergize in spi...

journal_title：Anesthesiology

authors： Bruce DJ,Peterson CD,Kitto KF,Akgün E,Lazzaroni S,Portoghese PS,Fairbanks CA,Wilcox GL

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Factors determining renal function at organ recovery in deceased kidney donors are not well established. METHODS:The authors studied the prevalence and risk factors associated with elevated prerecovery creatinine and calculated glomerular filtration rate in 458 deceased organ donors identified through the C...

journal_title：Anesthesiology

authors： Blasi-Ibanez A,Hirose R,Feiner J,Freise C,Stock PG,Roberts JP,Niemann CU

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Anesthetic drugs administered to immature animals may cause neurohistopathologic changes and alterations in behavior. The authors studied association between anesthetic exposure before age 4 yr and the development of reading, written language, and math learning disabilities (LD). METHODS:This was a populati...

journal_title：Anesthesiology

authors： Wilder RT,Flick RP,Sprung J,Katusic SK,Barbaresi WJ,Mickelson C,Gleich SJ,Schroeder DR,Weaver AL,Warner DO

更新日期：2009-04-01 00:00:00

abstract：:Critically ill patients must often breathe spontaneously through an endotracheal tube that acts as a fixed inspiratory and expiratory tubular airway resistor. Although this practice is common, its effect on the pattern of breathing is not known. The mean breathing patterns of seven normal, healthy male subjects and ei...

journal_title：Anesthesiology

authors： Weissman C,Askanazi J,Rosenbaum SH,Damask MC,Hyman AI,Kinney JM

更新日期：1986-03-01 00:00:00

abstract：:Assessment of competency in traditional graduate medical education has been based on observation of clinical care and classroom teaching. In anesthesiology, this has been relatively easy because of the high volume of care provided by residents under the direct observation of faculty in the operating room. With the mov...

journal_title：Anesthesiology

authors： Tetzlaff JE

更新日期：2007-04-01 00:00:00

abstract：:To determine whether administration of nitrous oxide, 50% and 70%, could provide analgesia and anxiolysis during venous cannulation in pediatric patients, 165 ASA Physical Status 1 patients scheduled for elective surgery were studied. Children, 3 weeks to 18 yr of age, were randomly assigned either to receive nitrous ...

journal_title：Anesthesiology

authors： Henderson JM,Spence DG,Komocar LM,Bonn GE,Stenstrom RJ

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:The dorsal horn of the spinal cord is a pivotal point for transmission of neuronal pain. During spinal and epidural anesthesia, the neurons of the dorsal horn are exposed to local anesthetics. Unfortunately, little is known about the action of local anesthetics on the major ionic conductances in dorsal horn ...

journal_title：Anesthesiology

authors： Olschewski A,Hempelmann G,Vogel W,Safronov BV

更新日期：1998-01-01 00:00:00

abstract：:Although it generally is agreed that halothane is a pulmonary vasodilator, its effect on venous admixture and hypoxic pulmonary vasoconstriction are more controversial. The effects of 2.4% halothane on pulmonary vascular resistance and venous admixture were investigated in an isolated canine lobe made atelectatic. Hal...

journal_title：Anesthesiology

authors： Johnson D,Hurst T,Mayers I

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Combining a hypnotic and an analgesic to produce sedation, analgesia, and surgical immobility required for clinical anesthesia is more common than administration of a volatile anesthetic alone. The aim of this study was to apply response surface methods to characterize the interactions between remifentanil a...

journal_title：Anesthesiology

authors： Manyam SC,Gupta DK,Johnson KB,White JL,Pace NL,Westenskow DR,Egan TD

更新日期：2006-08-01 00:00:00

abstract：:In order to elucidate the possible mechanism(s) by which opiates may affect cerebral and spinal circulation, and cerebral metabolism, cerebral blood flow (CBF) and spinal cord blood flow (SCBF) were measured simultaneously following intravenous or subarachnoid administration of morphine in dogs lightly anesthetized wi...

journal_title：Anesthesiology

authors： Matsumiya N,Dohi S

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Compared to other perioperative complications, failure to rescue (i.e., death after suffering a complication) is highest after perioperative myocardial infarction (a myocardial infarction that occurs intraoperatively or within 30 days after surgery). The purpose of this study was to identify patient and surg...

journal_title：Anesthesiology

authors： Mazzarello S,McIsaac DI,Beattie WS,Fergusson DA,Lalu MM

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Animal studies have provided considerable evidence to support a role of histamine in the central nervous system in thermoregulation, and premedication with a histamine H2 receptor antagonist before general anesthesia is used to reduce the risk of acid aspiration. The authors investigated whether premedicatio...

journal_title：Anesthesiology

authors： Hirose M,Hara Y,Matsusaki M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:The noble gas xenon (Xe) has been used as an inhalational anesthetic agent in clinical trials with little or no physiologic side effects. Like nitrous oxide, Xe is believed to exert minimal unwanted cardiovascular effects, and like nitrous oxide, the vapor concentration to achieve 1 minimum alveolar concentr...

journal_title：Anesthesiology

authors： Stowe DF,Rehmert GC,Kwok WM,Weigt HU,Georgieff M,Bosnjak ZJ

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is only approved for use in humans as an intravenous medication. An oral formulation may broaden the use and benefits of dexmedetomidine to numerous care settings. The authors hypothesized that oral dexmedetomidine (300 mcg to 700 mcg) would result in plasma concentrations consistent with sed...

journal_title：Anesthesiology

authors： Chamadia S,Pedemonte JC,Hobbs LE,Deng H,Nguyen S,Cortinez LI,Akeju O

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Repetitive C-fiber stimulation induces a state of facilitated processing of sensory information in the dorsal horn, while chronic nerve compression gives rise to a hyperalgesic state, characterized by spontaneous neuronal activity generated by voltage-sensitive sodium channels, as well as spinal facilitation...

journal_title：Anesthesiology

authors： Abram SE,Yaksh TL

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:We describe the anesthetic management for a new surgical procedure: laser ablation of emphysematous bullae via thoracoscope. Although thoracoscopy is not new, this is the first description of a series of patients with bilateral, chronic lung disease who underwent long periods of one-lung ventilation (OLV) du...

journal_title：Anesthesiology

authors： Barker SJ,Clarke C,Trivedi N,Hyatt J,Fynes M,Roessler P

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:In animals, systemic and intrathecal administration of the alpha2 -adrenergic receptor agonist dexmedetomidine results in robust antinociceptive effects in models of heat pain. In humans, systemically administered dexmedetomidine is approved for sedating patients in the intensive care unit. However, whether ...

journal_title：Anesthesiology

authors： Angst MS,Ramaswamy B,Davies MF,Maze M

更新日期：2004-09-01 00:00:00

abstract：:Rats were given standardized injections of 3H-L-proline into the trigeminal ganglion and 14C-lidocaine hydrochloride at the infraorbital foramen. The 3H-L-proline was always injected 2.5 h before removal of the nerve. Lidocaine, 1, 2, and 4%, produced a concentration-related inhibition of entry of 3H-labeled rapid axo...

journal_title：Anesthesiology

authors： Fink BR,Kish SJ

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) 130/0.4 may impair blood coagulation less than other HES solutions and, thus, may be used at larger doses without increasing the risk of postoperative bleeding. This study tested the hypothesis that volume replacement with 6% HES 130/0.4 at a dose of up to 50 ml/kg does not increase...

journal_title：Anesthesiology

authors： Kasper SM,Meinert P,Kampe S,Görg C,Geisen C,Mehlhorn U,Diefenbach C

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The tuberomammillary histaminergic neurons are involved in the sedative component of anesthetic action. The nucleus basalis magnocellularis (NBM) in the basal forebrain receives dense excitatory innervation from the tuberomammillary nucleus and is recognized as an important site of sleep-wake regulation. Thi...

journal_title：Anesthesiology

authors： Luo T,Leung LS

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The Atenolol study of 1996 provided evidence that perioperative β-blockade reduced postsurgical mortality. In 1998, the indications for perioperative β-blockade were codified as the Perioperative Cardiac Risk Reduction protocol and implemented at the San Francisco Veterans Affairs Medical Center. The current...

journal_title：Anesthesiology

authors： Wallace AW,Au S,Cason BA

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:This propensity score-matched cohort study evaluates the effect of anesthetic technique on a 30-day mortality after total hip or knee arthroplasty. METHODS:All patients who had hip or knee arthroplasty between January 1, 2003, and December 31, 2014, were evaluated. The principal exposure was spinal versus g...

journal_title：Anesthesiology

authors： Perlas A,Chan VW,Beattie S

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Knowledge of normal front teeth-to-carina distance (FT-C) might prevent accidental bronchial intubation. The aim of the current study was to measure FT-C and to examine whether the Morgan formula for oral intubation depth, i.e., endotracheal tube (ETT) position at front teeth (cm) = 0.10 x height (cm) + 5, g...

journal_title：Anesthesiology

authors： Hunyady AI,Pieters B,Johnston TA,Jonmarker C

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:We have previously shown that intralipid (lipid emulsion) protects the heart against ischemia/reperfusion injury and bupivacaine-induced cardiotoxicity. However, the precise underlying mechanisms are not fully understood. Here we explored the hypothesis that free fatty acid receptor-1 or G-protein-coupled re...

journal_title：Anesthesiology

authors： Umar S,Li J,Hannabass K,Vaillancourt M,Cunningham CM,Moazeni S,Mahajan A,Eghbali M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Initial anesthetic-induced hypothermia results largely from core-to-peripheral redistribution of heat. Nifedipine administration may minimize hypothermia by inducing vasodilation well before induction of anesthesia. Although vasodilation would redistribute heat to peripheral tissues, thermoregulatory respons...

journal_title：Anesthesiology

authors： Vassilieff N,Rosencher N,Sessler DI,Conseiller C,Lienhart A

更新日期：1994-01-01 00:00:00