Combination of a δ-opioid Receptor Agonist and Loperamide Produces Peripherally-mediated Analgesic Synergy in Mice.

abstract：BACKGROUND:Whether anesthetic agents administered during gamete intrafallopian transfer (GIFT) affect reproductive outcome is controversial. This multicenter pilot trial and survey had two purposes: to evaluate the effect of propofol, nitrous oxide, midazolam, and isoflurane on pregnancy outcome after GIFT, and to dete...

journal_title：Anesthesiology

authors： Beilin Y,Bodian CA,Mukherjee T,Andres LA,Vincent RD Jr,Hock DL,Sparks AE,Munson AK,Minnich ME,Steinkampf MP,Christman GM,McKay RS,Eisenkraft JB

更新日期：1999-01-01 00:00:00

abstract：:The effect of enflurane (2% and 4% inspired) on left ventricular (LV) function were examined in chronically instrumented dogs, both intact and after isolation of their hearts and lungs from the systemic circulation. Enflurane in the intact dogs increased heart rate (32 +/- 5% with 2% and 41 +/- 4% with 4%) and elicite...

journal_title：Anesthesiology

authors： Zimpfer M,Gilly H,Krösl P,Schlag G,Steinbereithner K

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:General anesthetics reduce neuronal death caused by focal cerebral ischemia in rodents and by in vitro ischemia in cultured neurons and brain slices. However, in intact animals, the protective effect may enhance neuronal survival for only several days after an ischemic injury, possibly because anesthetics pr...

journal_title：Anesthesiology

authors： Sullivan BL,Leu D,Taylor DM,Fahlman CS,Bickler PE

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) is a devastating condition with an estimated mortality exceeding 30%. There are data suggesting risk factors for ARDS development in high-risk populations, but few data are available in lower incidence populations. Using risk-matched analysis and a combination of cl...

journal_title：Anesthesiology

authors： Blum JM,Stentz MJ,Dechert R,Jewell E,Engoren M,Rosenberg AL,Park PK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Pulse oximeters have been reported to fail to record data in 1.12-2.50% of cases in which anesthesia records were handwritten. There is reason to believe that these may be underestimates. Computerized anesthesia records may provide insight into the true incidence of pulse oximetry data failures and factors t...

journal_title：Anesthesiology

authors： Reich DL,Timcenko A,Bodian CA,Kraidin J,Hofman J,DePerio M,Konstadt SN,Kurki T,Eisenkraft JB

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The minimum time interval between administration of oral midazolam and separation of children from their parents that ensures good anterograde amnesia has not been previously determined. This is of particular importance in a busy operating room setting where schedule delays secondary to midazolam administrat...

journal_title：Anesthesiology

authors： Kain ZN,Hofstadter MB,Mayes LC,Krivutza DM,Alexander G,Wang SM,Reznick JS

更新日期：2000-09-01 00:00:00

abstract：:To determine if continuous positive airway pressure (CPAP) or expiratory positive airway pressure (EPAP) is superior for achieving or maintaining effective lung volume in spontaneously breathing critically ill patients in acute respiratory failure, the authors measured functional residual capacity (FRC), airway and es...

journal_title：Anesthesiology

authors： Schlobohm RM,Falltrick RT,Quan SF,Katz JA

更新日期：1981-10-01 00:00:00

abstract：:Thirty-six halogenated Me Et ethers have been synthesized for evaluation as volatile anesthetics. Eleven of the ethers were too unstable to test, and, of the remaining 25, 13 had promising anesthetic properties in mice and are suitable for study in larger animals. Those ethers having one H with at least 2 halogens oth...

journal_title：Anesthesiology

authors： Terrell RC

更新日期：2008-03-01 00:00:00

abstract：:Distribution and elimination of lidocaine and mepivacaine were studies in 114 subjects after obstetric epidural anesthesia, Epinephrine significantly lowered the concentrations of lidocaine in the mothers' circulations by about 33 per cent, and the concentrations of mepivacaine by about 22 per cent. It also significan...

journal_title：Anesthesiology

authors： Brown WU,Bell GC,Lurie AO,Weiss B,Scanlon JW,Alper MH

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:Sevoflurane is a volatile general anesthetic that differs in chemical nature from the gaseous anesthetic nitrous oxide. In a controlled laboratory setting, the authors characterized the subjective, psychomotor, and analgesic effects of sevoflurane and nitrous oxide at two equal minimum alveolar subanesthetic...

journal_title：Anesthesiology

authors： Galinkin JL,Janiszewski D,Young CJ,Klafta JM,Klock PA,Coalson DW,Apfelbaum JL,Zacny JP

更新日期：1997-11-01 00:00:00

abstract：:In a recent editorial, Kapur described perioperative nausea and vomiting as "the big 'little problem' following ambulatory surgery."257 Although the actual morbidity associated with nausea is relatively low in health outpatients, it should not be considered an unavoidable part of the perioperative experience. The avai...

journal_title：Anesthesiology

authors： Watcha MF,White PF

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Isoflurane anesthesia produces cardiovascular and respiratory depression, although the specific mechanisms are not fully understood. Cranial visceral afferents, which innervate the heart and lungs, synapse centrally onto neurons within the medial portion of the nucleus tractus solitarius (NTS). Isoflurane mo...

journal_title：Anesthesiology

authors： Peters JH,McDougall SJ,Mendelowitz D,Koop DR,Andresen MC

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Hypoalbuminemia may increase the risk of acute kidney injury (AKI). The authors investigated whether the immediate preoperative administration of 20% albumin solution affects the incidence of AKI after off-pump coronary artery bypass surgery. METHODS:In this prospective, single-center, randomized, parallel-...

journal_title：Anesthesiology

authors： Lee EH,Kim WJ,Kim JY,Chin JH,Choi DK,Sim JY,Choo SJ,Chung CH,Lee JW,Choi IC

更新日期：2016-05-01 00:00:00

abstract：:The authors present a simple and clinically applicable method for the serial monitoring of pulmonary microvascular enzyme function in vivo. This method requires the intravenous injection of trace amounts of a radiolabelled substrate and the collection of a single arterial blood sample. Simultaneous measurement of pulm...

journal_title：Anesthesiology

authors： Toivonen HJ,Makari N,Catravas JD

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Pain and nausea are the most common challenges in postoperative recovery after mastectomy. Preventive measures include multimodal analgesia with preoperative glucocorticoid. The aim of this study was to investigate whether 24 mg of preoperative dexamethasone was superior to 8 mg on early recovery after maste...

journal_title：Anesthesiology

authors： Steinthorsdottir KJ,Awada HN,Abildstrøm H,Kroman N,Kehlet H,Kvanner Aasvang E

更新日期：2020-04-01 00:00:00

abstract：:Neurophysiologic studies indicate that local anesthetic-induced seizures are generated in subcortical brain structures. The authors utilized a quantitative autoradiographic technique to measure cerebral metabolism during lidocaine-induced seizure activity in rats anesthetized with nitrous oxide. Local cerebral metabol...

journal_title：Anesthesiology

authors： Ingvar M,Shapiro HM

更新日期：1981-01-01 00:00:00

abstract：:We sought to determine the percent delivery by metered-dose inhaler (MDI) of a preparation of salbutamol (albuterol) to the distal end of either pediatric-size tracheal tubes or a narrow-gauge catheter. A bench model consisting of a swivel actuator; 3.0-6.0-mm ID tracheal tubes all 16 cm in length or a 19-G (standard ...

journal_title：Anesthesiology

authors： Taylor RH,Lerman J

更新日期：1991-02-01 00:00:00

abstract：:Exposure of resting rat diaphragm for one hour in vitro to halothane (1-1.5, 2-2.5 and 4-4.5 per cent in oxygen) produced significant alterations of intracellular glucose disposition. Glycolysis (as measured by lactate production) increased, while glycogen formation was inhibited in a dose-related fashion. Net glucose...

journal_title：Anesthesiology

authors： Rosenberg H,Haugaard N,Haugaard ES

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Whether intraoperative use of hydroxyethyl starch impairs kidney function remains unknown. The authors thus tested the primary hypothesis that Hextend promotes renal injury in surgical patients. Secondarily, the authors evaluated the dose-outcome relationship, in-hospital and 90-day mortality, and whether th...

journal_title：Anesthesiology

authors： Kashy BK,Podolyak A,Makarova N,Dalton JE,Sessler DI,Kurz A

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The mechanism of the protective actions of volatile anesthetics in ischemic myocardium has not been clearly elucidated. The role of myocardial adenosine triphosphate-regulated potassium (KATP) channels in isoflurane-induced enhancement of recovery of regional contractile function after multiple brief occlusi...

journal_title：Anesthesiology

authors： Kersten JR,Schmeling TJ,Hettrick DA,Pagel PS,Gross GJ,Warltier DC

更新日期：1996-10-01 00:00:00

abstract：:To determine the effects of cardiopulmonary bypass (CPB) and hypothermia on the neuromuscular blockade produced by pancuronium, this relaxant was infused intravenously into 10 anesthetized patients to produce and maintain 90% depression of the twitch tension of the adductor pollicis muscle following supramaximal ulnar...

journal_title：Anesthesiology

authors： d'Hollander AA,Duvaldestin P,Henzel D,Nevelsteen M,Bomblet JP

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:The authors' objective was to assess the role of protein kinase C (PKC) and nitric oxide synthase (NOS) in mediating the effects of propofol on diabetic cardiomyocyte contractility, intracellular free Ca2+ concentration ([Ca2+]i), and myofilament Ca2+ sensitivity. METHODS:Freshly isolated ventricular myocyt...

journal_title：Anesthesiology

authors： Wickley PJ,Shiga T,Murray PA,Damron DS

更新日期：2006-05-01 00:00:00

abstract：:The effects of continuous positive airway pressure (CPAP) on cardiovascular dynamics and pulmonary shunt (QS/QT) were investigated in 12 dogs before and during sodium nitroprusside infusion that decreased mean arterial blood pressure 40-50 per cent. Before nitroprusside infusion, 5 cm H2O CPAP significantly, P less th...

journal_title：Anesthesiology

authors： Hodges MR,Stanley TH,Johansen RK

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Buprenorphine, a partial μ-opioid receptor agonist and κ-opioid receptor antagonist, is an effective analgesic. The effects of buprenorphine on sleep have not been well characterized. This study tested the hypothesis that an antinociceptive dose of buprenorphine decreases sleep and decreases adenosine concen...

journal_title：Anesthesiology

authors： Gauthier EA,Guzick SE,Brummett CM,Baghdoyan HA,Lydic R

更新日期：2011-10-01 00:00:00

abstract：:Although Ernest Shackleton's Endurance Antarctic expedition of 1914 to 1916 is a famous epic of survival, the medical achievements of the two expedition doctors have received little formal examination. Marooned on Elephant Island after the expedition ship sank, Drs. Macklin and McIlroy administered a chloroform anesth...

journal_title：Anesthesiology

authors： Firth PG

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Preterm and ex-preterm infants are at risk for life-threatening apnea after general anesthesia. The authors attempted to define the postconceptual age beyond which apnea is less likely to occur and to identify the factors that predispose to postanesthetic apnea. METHODS:Ninety-one infants younger than 60 we...

journal_title：Anesthesiology

authors： Malviya S,Swartz J,Lerman J

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Hypotension induced by sodium nitroprusside can minimize intraoperative blood loss. The release of endogenous catecholamines can influence adrenoceptors of platelets and thus might change the ability of platelets to aggregate. METHODS:Forty patients undergoing nasal septum, tympanoplastic, or sphenoid sinus...

journal_title：Anesthesiology

authors： Dietrich GV,Heesen M,Boldt J,Hempelmann G

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:The noble gas xenon (Xe) has been used as an inhalational anesthetic agent in clinical trials with little or no physiologic side effects. Like nitrous oxide, Xe is believed to exert minimal unwanted cardiovascular effects, and like nitrous oxide, the vapor concentration to achieve 1 minimum alveolar concentr...

journal_title：Anesthesiology

authors： Stowe DF,Rehmert GC,Kwok WM,Weigt HU,Georgieff M,Bosnjak ZJ

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Myocardial contractility is regulated by intracellular concentration of free Ca2+ ([Ca2'],) and myofilament Ca2+ sensitivity. The objective of this study was to elucidate the direct effects of thiopental on cardiac excitation-contraction coupling using individual, field-stimulated ventricular myocytes. METH...

journal_title：Anesthesiology

authors： Kanaya N,Zakhary DR,Murray PA,Damron DS

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Previous studies reported that thoracic epidural anesthesia (TEA) protected against a decrease in gastric intramucosal pH, suggesting that TEA increased gut mucosal perfusion. The current study examines the effects of TEA on ileal mucosa using intravital microscopy in anesthetized rats. METHODS:Nineteen rat...

journal_title：Anesthesiology

authors： Sielenkämper AW,Eicker K,Van Aken H

更新日期：2000-09-01 00:00:00