Preoperative and intraoperative predictors of postoperative acute respiratory distress syndrome in a general surgical population.

abstract：BACKGROUND:Intrathecal methylprednisolone acetate (MPA) has been used in patients with chronic pain syndromes. Its safety has been debated after reports of adverse events. No systematic preclinical evaluation of MPA has been reported. In the current study, the acute and long-term effects of intrathecal MPA on dog spina...

journal_title：Anesthesiology

authors： Rijsdijk M,van Wijck AJ,Kalkman CJ,Meulenhoff PC,Grafe MR,Steinauer J,Yaksh TL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The long-lasting high-affinity opioid buprenorphine has complex pharmacology, including ceiling effects with respect to analgesia and respiratory depression. Plasma concentrations of the major buprenorphine metabolites norbuprenorphine, buprenorphine-3-glucuronide, and norbuprenorphine-3-glucuronide approxim...

journal_title：Anesthesiology

authors： Brown SM,Holtzman M,Kim T,Kharasch ED

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Mice lacking calsequestrin-1 (CASQ1-null), a Ca-binding protein that modulates the activity of Ca release in the skeletal muscle, exhibit lethal hypermetabolic episodes that resemble malignant hyperthermia in humans when exposed to halothane or heat stress. METHODS:Because oxidative species may play a criti...

journal_title：Anesthesiology

authors： Michelucci A,Paolini C,Canato M,Wei-Lapierre L,Pietrangelo L,De Marco A,Reggiani C,Dirksen RT,Protasi F

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Hyperkalemic cardiac arrest after the administration of succinylcholine (SCh) to critically ill intensive care patients has been attributed to changes in the acetylcholine receptors (AChRs) at the muscle membrane. The current study attempts to characterize the contributory roles of chronic administration of ...

journal_title：Anesthesiology

authors： Yanez P,Martyn JA

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Resiniferatoxin is a potent capsaicin analog. Intrathecal administration leads to selective, prolonged opening of the transient receptor potential V1 ion channel, which is localized mainly to C-fiber primary afferent nociceptive sensory neurons. Following work in laboratory animals, the authors explored the ...

journal_title：Anesthesiology

authors： Brown DC,Iadarola MJ,Perkowski SZ,Erin H,Shofer F,Laszlo KJ,Olah Z,Mannes AJ

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Postoperative visual loss after prone spine surgery is increasingly reported in association with ischemic optic neuropathy, but its etiology is unknown. METHODS:To describe the clinical characteristics of these patients, the authors analyzed a retrospectively collected series of 93 spine surgery cases volun...

journal_title：Anesthesiology

authors： Lee LA,Roth S,Posner KL,Cheney FW,Caplan RA,Newman NJ,Domino KB

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Studies have shown that long-term increase in the excitability of single wide dynamic range neurones in the spinal dorsal horn of rats may be induced after tetanic stimulation to the sciatic nerve. This sensory event is possibly an in vivo counterpart of long-term potentiation, described in the brain. This s...

journal_title：Anesthesiology

authors： Rygh LJ,Green M,Athauda N,Tjølsen A,Dickenson AH

更新日期：2000-01-01 00:00:00

abstract：WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Ketamine is an N-methyl-D-aspartate receptor antagonist that reduces temporal summation of pain and modulates antinociception. Ketamine infusions can produce significant relief of neuropathic pain, but the treatment is resource i...

journal_title：Anesthesiology

authors： Bosma RL,Cheng JC,Rogachov A,Kim JA,Hemington KS,Osborne NR,Venkat Raghavan L,Bhatia A,Davis KD

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Xenon has been shown to be neuroprotective in several models of in vitro and in vivo neuronal injury. However, its putative neuroprotective properties have not been evaluated in focal cerebral ischemia. The purpose of this study was to determine if xenon offers neuroprotection in a mouse model of middle cere...

journal_title：Anesthesiology

authors： Homi HM,Yokoo N,Ma D,Warner DS,Franks NP,Maze M,Grocott HP

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Ca is the dominant second messenger in primary sensory neurons. In addition, disrupted Ca signaling is a prominent feature in pain models involving peripheral nerve injury. Standard cytoplasmic Ca recording techniques use high K or field stimulation and dissociated neurons. To compare findings in intact dors...

journal_title：Anesthesiology

authors： Gemes G,Rigaud M,Koopmeiners AS,Poroli MJ,Zoga V,Hogan QH

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The mechanism of the protective actions of volatile anesthetics in ischemic myocardium has not been clearly elucidated. The role of myocardial adenosine triphosphate-regulated potassium (KATP) channels in isoflurane-induced enhancement of recovery of regional contractile function after multiple brief occlusi...

journal_title：Anesthesiology

authors： Kersten JR,Schmeling TJ,Hettrick DA,Pagel PS,Gross GJ,Warltier DC

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Forced-air warming is sometimes unable to maintain perioperative normothermia. Therefore, the authors compared heat transfer, regional heat distribution, and core rewarming of forced-air warming with a novel circulating-water garment. METHODS:Nine volunteers were each evaluated on two randomly ordered study...

journal_title：Anesthesiology

authors： Taguchi A,Ratnaraj J,Kabon B,Sharma N,Lenhardt R,Sessler DI,Kurz A

更新日期：2004-05-01 00:00:00

abstract：:In late 1846, following his successful public demonstrations of surgical anesthesia, Boston dentist William T. G. Morton selected Letheon as the commercial name for the ether-based "preparation" he had used to produce insensibility to pain. We have not identified a first-hand account of the coinage of Letheon. Althoug...

journal_title：Anesthesiology

authors： Haridas RP,Gionfriddo M,Bause GS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Intrathecal administration of opioids may cause lower urinary tract dysfunction. In this study, the authors compared the effects of morphine and sufentanil administered intrathecally in a randomized double-blind fashion (two doses each) on lower urinary tract function in healthy male volunteers. METHODS:Uro...

journal_title：Anesthesiology

authors： Kuipers PW,Kamphuis ET,van Venrooij GE,van Roy JP,Ionescu TI,Knape JT,Kalkman CJ

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Preterm and ex-preterm infants are at risk for life-threatening apnea after general anesthesia. The authors attempted to define the postconceptual age beyond which apnea is less likely to occur and to identify the factors that predispose to postanesthetic apnea. METHODS:Ninety-one infants younger than 60 we...

journal_title：Anesthesiology

authors： Malviya S,Swartz J,Lerman J

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Because the nuclear factor-κB (NF-κB) coupled pathway is believed to amplify inflammation prevailing in sepsis, the authors tested the hypotheses that the insertion-deletion polymorphism (-94ins/delATTG) (1) alters nuclear translocation of nuclear factor-κB and activator protein-1 (NF-κB1) in monocytes after...

journal_title：Anesthesiology

authors： Adamzik M,Schäfer S,Frey UH,Becker A,Kreuzer M,Winning S,Frede S,Steinmann J,Fandrey J,Zacharowski K,Siffert W,Peters J,Hartmann M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The concept of the axillary "sheath" has been a central tenet of brachial plexus regional anesthesia for many years. Recent investigations have cast doubt on its nature and existence. This study further examines the issue. METHODS:Computerized axial tomographic dye studies were performed using continuous ca...

journal_title：Anesthesiology

authors： Cornish PB,Leaper C

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Propofol may produce amnesia by affecting encoding. The hypothesis that propofol weakens encoding was tested by measuring regional cerebral blood flow during verbal encoding. METHODS:Seventeen volunteer participants (12 men; aged 30.4 +/- 6.5 yr) had regional cerebral blood flow measured using H2O positron ...

journal_title：Anesthesiology

authors： Veselis RA,Pryor KO,Reinsel RA,Mehta M,Pan H,Johnson R Jr

更新日期：2008-08-01 00:00:00

abstract：:Patients with mitral valve disease can develop pulmonary artery hypertension that persists after mitral valve replacement. In 1987, nitric oxide (NO) was reported to be an important factor accounting for the biologic activity of endothelium-derived relaxing factor. Inhaled NO was subsequently reported to be a selectiv...

journal_title：Anesthesiology

authors： Girard C,Lehot JJ,Pannetier JC,Filley S,Ffrench P,Estanove S

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The authors hypothesized a difference in plasma-effect site equilibration, depicted by a first-order constant k(e0), depending on the injection rate of propofol. METHODS:Sixty-one patients received 2.5 mg/kg propofol given as a bolus or as a 1-, 2-, or 3-min infusion. The Bispectral Index was used to monito...

journal_title：Anesthesiology

authors： Struys MM,Coppens MJ,De Neve N,Mortier EP,Doufas AG,Van Bocxlaer JF,Shafer SL

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:In this open, randomized study, the pharmacokinetics, clinical efficacy, and safety of a 48-h continuous interscalene infusion of 2 mg/ml ropivacaine for postoperative pain relief were investigated in patients undergoing open major shoulder surgery. METHODS:An initial interscalene block with 30 ml ropivacai...

journal_title：Anesthesiology

authors： Ekatodramis G,Borgeat A,Huledal G,Jeppsson L,Westman L,Sjövall J

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The current study was designed to investigate the influence of pretreatment with the oxygen radical scavengers polyethylene glycol superoxide dismutase and catalase (SODCAT) on altered opioid-induced pial artery dilation after fluid percussion brain injury (FPI) in the newborn pig. It has been observed previ...

journal_title：Anesthesiology

authors： Thorogood MC,Armstead WM

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:A high proportion of patients having cardiac bypass surgery receive erythrocyte transfusions. Decisions about when to transfuse patients having surgery for coronary artery disease may impact on erythrocyte utilization and patient morbidity and mortality. There are no published data about the factors that inf...

journal_title：Anesthesiology

authors： Shehata N,Wilson K,Mazer CD,Tomlinson G,Streiner D,Hebert P,Naglie G

更新日期：2006-07-01 00:00:00

abstract：:ECG changes suggestive of myocardial ischemia are common during cesarean delivery under regional anesthesia. To determine the time course, duration, and significance of these ECG changes, we monitored 111 parturients with continuous ambulatory ECG (Holter) during and after cesarean delivery. Twenty-two parturients und...

journal_title：Anesthesiology

authors： Mathew JP,Fleisher LA,Rinehouse JA,Sevarino FB,Sinatra RS,Nelson AH,Prokop EK,Rosenbaum SH

更新日期：1992-10-01 00:00:00

abstract：:Fentanyl is used as an analgesic in small doses (1-2 micrograms X kg-1) and as an anesthetic in very large doses (greater than 150 micrograms X kg-1). It has been demonstrated that the effects of fentanyl correlate with its concentrations in plasma. It is important, therefore, to know whether or not the pharmacokineti...

journal_title：Anesthesiology

authors： Murphy MR,Hug CC Jr,McClain DA

更新日期：1983-12-01 00:00:00

abstract：WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Craniotomy for brain tumor displays significant morbidity and mortality, and no score is available to discriminate high-risk patients. Our objective was to validate a prediction score for postoperative neurosurgical complications...

journal_title：Anesthesiology

authors： Cinotti R,Bruder N,Srairi M,Paugam-Burtz C,Beloeil H,Pottecher J,Geeraerts T,Atthar V,Guéguen A,Triglia T,Josserand J,Vigouroux D,Viquesnel S,Lakhal K,Galliez M,Blanloeil Y,Le Thuaut A,Feuillet F,Rozec B,Asehnoune K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Crystalloid solutions are used to restore intravascular volume in septic patients, but each solution has limitations. The authors compared the effects of three crystalloid solutions on hemodynamics, organ function, microcirculation, and survival in a sepsis model. METHODS:Peritonitis was induced by injectio...

journal_title：Anesthesiology

authors： Orbegozo D,Su F,Santacruz C,He X,Hosokawa K,Creteur J,De Backer D,Vincent JL

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:In the event of trauma, emergency reversal of anticoagulation therapy may be required. However, no specific reversal agents are routinely available for the direct oral anticoagulants such as dabigatran. The authors investigated four-factor prothrombin complex concentrate (PCC) for treating dabigatran-induced...

journal_title：Anesthesiology

authors： Honickel M,Braunschweig T,van Ryn J,Ten Cate H,Spronk HM,Rossaint R,Grottke O

更新日期：2015-12-01 00:00:00

abstract：:Decreased urinary output (Vu ml/min) after institution of PEEP is attributed to a variety of mechanisms including decreased cardiac output and renal blood flow (RBF), activation of neurohormonal reflexes, increased catecholamines, plasma renin activity (PRA), and antidiuretic hormone (ADH) release. To evaluate these f...

journal_title：Anesthesiology

authors： Payen DM,Farge D,Beloucif S,Leviel F,De La Coussaye JE,Carli P,Wirquin V

更新日期：1987-01-01 00:00:00

abstract：:Critically ill patients often suffer from multiple organ failures involving lung, kidney, liver, or brain. Genomic, proteomic, and metabolomic approaches highlight common injury mechanisms leading to acute organ failure. This underlines the need to focus on therapeutic strategies affecting multiple injury pathways. Th...

journal_title：Anesthesiology

authors： Monsel A,Zhu YG,Gennai S,Hao Q,Liu J,Lee JW

更新日期：2014-11-01 00:00:00