Anesthesia Technique and Mortality after Total Hip or Knee Arthroplasty: A Retrospective, Propensity Score-matched Cohort Study.

abstract：BACKGROUND:Anesthetic drugs administered to immature animals may cause neurohistopathologic changes and alterations in behavior. The authors studied association between anesthetic exposure before age 4 yr and the development of reading, written language, and math learning disabilities (LD). METHODS:This was a populati...

journal_title：Anesthesiology

authors： Wilder RT,Flick RP,Sprung J,Katusic SK,Barbaresi WJ,Mickelson C,Gleich SJ,Schroeder DR,Weaver AL,Warner DO

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Preservation of gut integrity has become a therapeutic goal to obviate bacterial translocation in the critically ill. The authors examined whether olprinone, a phosphodiesterase III inhibitor, protected functional and structural integrity of gut mucosa against acute progressive hypoxia. METHODS:Thirty-two a...

journal_title：Anesthesiology

authors： Satoh T,Morisaki H,Ai K,Kosugi S,Yamamoto M,Serita R,Kotake Y,Takeda J

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Given the current practice environment, it is important to determine the anesthetic technique with the highest patient acceptance and lowest associated costs. The authors compared three commonly used anesthetic techniques for anorectal procedures in the ambulatory setting. METHODS:Ninety-three consenting ad...

journal_title：Anesthesiology

authors： Li S,Coloma M,White PF,Watcha MF,Chiu JW,Li H,Huber PJ Jr

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Valdecoxib and its intravenous prodrug parecoxib are reported to increase thromboembolic risk after coronary artery bypass grafting. The authors conducted a randomized trial to examine their safety and analgesic efficacy in patients recovering from major noncardiac surgical procedures. METHODS:The trial was...

journal_title：Anesthesiology

authors： Nussmeier NA,Whelton AA,Brown MT,Joshi GP,Langford RM,Singla NK,Boye ME,Verburg KM

更新日期：2006-03-01 00:00:00

abstract：:To determine if a relationship exists between perioperative myocardial ischemia (ST segment depression greater than or equal to 0.1 mV) and postoperative myocardial infarction (PMI), nonparticipating observers recorded all ECG, hemodynamic, and other events between arrival of patients in the operating room and onset o...

journal_title：Anesthesiology

authors： Slogoff S,Keats AS

更新日期：1985-02-01 00:00:00

abstract：:This study was designed to evaluate a new drug delivery system. The authors undertook to determine if microdroplets prepared by encapsulating volatile anesthetics with a membrane of lecithin could be used for local anesthesia. Local anesthesia was determined by monitoring the response of the rat to tail clamping and e...

journal_title：Anesthesiology

authors： Haynes DH,Kirkpatrick AF

更新日期：1985-11-01 00:00:00

abstract：:Clonidine, an alpha 2-adrenergic agonist, can potentiate opioid-induced analgesia. In a double-blind placebo-controlled study in human volunteers, we sought to determine whether clonidine also potentiates opioid-induced respiratory depression. Hypercapnic ventilatory responses (minute ventilation, mean inspiratory flo...

journal_title：Anesthesiology

authors： Jarvis DA,Duncan SR,Segal IS,Maze M

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Isoflurane has been said to be more ventilatory depressant than halothane. However, data for comparing the respiratory effects of halothane and isoflurane in humans are insufficient at this time. The aim of this study was to extend our understanding of the nature of the central, as opposed to peripheral, ven...

journal_title：Anesthesiology

authors： Canet J,Sanchis J,Zegrí A,Llorente C,Navajas D,Casan P

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The minimum alveolar concentration (MAC) of volatile anesthetics is decreased during pregnancy, but MAC in the early postpartum period has not been reported. The aim of this study was to determine the MAC of isoflurane and to evaluate the relation between MAC and serum progesterone and beta-endorphin in pati...

journal_title：Anesthesiology

authors： Zhou HH,Norman P,DeLima LG,Mehta M,Bass D

更新日期：1995-06-01 00:00:00

abstract：:We recorded the frequency with which anesthesia personnel came in contact with patient body fluids in order to provide an empirical basis for the recommendation of relevant precautions. Anesthesia personnel completed a questionnaire when performing a range of standardized procedures. The rate of contact with blood was...

journal_title：Anesthesiology

authors： Kristensen MS,Sloth E,Jensen TK

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Days alive and out of hospital is a potentially useful patient-centered quality measure for perioperative care in adult surgical patients. However, there has been very limited prior validation of this endpoint with respect to its ability to capture differences in patient-level risk factor profiles and longer...

journal_title：Anesthesiology

authors： Jerath A,Austin PC,Wijeysundera DN

更新日期：2019-07-01 00:00:00

abstract：:The authors studied the influence of locally administered isoflurane anesthesia on the pulmonary vascular response to regional alveolar hypoxia (hypoxic pulmonary vasoconstriction [HPV]) over a range of cardiac outputs (COs) in seven mechanically ventilated, closed-chest dogs. The right lung was ventilated with 100% O...

journal_title：Anesthesiology

authors： Domino KB,Borowec L,Alexander CM,Williams JJ,Chen L,Marshall C,Marshall BE

更新日期：1986-04-01 00:00:00

abstract：WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Traumatic brain injury induces cellular proliferation in the hippocampus, which generates new neurons and glial cells during recovery. This process is regulated by N-methyl-D-aspartate-type glutamate receptors, which are inhibite...

journal_title：Anesthesiology

authors： Peters AJ,Villasana LE,Schnell E

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Previous studies reported that thoracic epidural anesthesia (TEA) protected against a decrease in gastric intramucosal pH, suggesting that TEA increased gut mucosal perfusion. The current study examines the effects of TEA on ileal mucosa using intravital microscopy in anesthetized rats. METHODS:Nineteen rat...

journal_title：Anesthesiology

authors： Sielenkämper AW,Eicker K,Van Aken H

更新日期：2000-09-01 00:00:00

abstract：:Binding of thiopental to proteins in plasma from healthy, cirrhotic, and uremic subjects was studied using equilibrium dialysis. In plasma from healthy volunteers 28.0 plus or minus 0.9 per cent of thiopental was unbound. In plasma from patients with hepatic disease 53.0 plus or minus 2.1 per cent was unbound, while i...

journal_title：Anesthesiology

authors： Ghoneim MM,Pandya H

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Transient receptor potential vanilloid 1 channels integrate nociceptive stimuli and are predominantly expressed by unmyelinated C-fiber nociceptors, but not low-threshold mechanoreceptive sensory or motor fibers. A recent report showed that the transient receptor potential vanilloid 1 channel agonist capsaic...

journal_title：Anesthesiology

authors： Gerner P,Binshtok AM,Wang CF,Hevelone ND,Bean BP,Woolf CJ,Wang GK

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Adding sodium bicarbonate to lidocaine to enhance its efficacy during peripheral nerve block is controversial. The authors studied the effect of adding sodium bicarbonate to lidocaine with and without epinephrine versus equivalent alkalinization by sodium hydroxide (NaOH) on onset, degree, and duration of pe...

journal_title：Anesthesiology

authors： Sinnott CJ,Garfield JM,Thalhammer JG,Strichartz GR

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Rocuronium, like other steroidal nondepolarizing muscle relaxants, may in part be eliminated by the liver. To determine the influence of liver disease on its neuromuscular blocking effect, we studied the pharmacokinetics and pharmacodynamics of rocuronium in patients with cirrhosis. METHODS:Eighteen patient...

journal_title：Anesthesiology

authors： Khalil M,D'Honneur G,Duvaldestin P,Slavov V,De Hys C,Gomeni R

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Lactate has been shown to be a prognostic biomarker in trauma. Although lactate clearance has already been proposed as an intermediate endpoint in randomized trials, its precise role in trauma patients remains to be determined. METHODS:Blood lactate levels and lactate clearance (LC) were calculated at admis...

journal_title：Anesthesiology

authors： Régnier MA,Raux M,Le Manach Y,Asencio Y,Gaillard J,Devilliers C,Langeron O,Riou B

更新日期：2012-12-01 00:00:00

abstract：:Complications after major surgery are a leading cause of morbidity and mortality. The etiology of postoperative complications is complex, but poor cardiorespiratory reserve appears to be a key factor. There is increasing interest in the use of central and mixed venous oxygen saturation to guide therapeutic interventio...

journal_title：Anesthesiology

authors： Shepherd SJ,Pearse RM

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to generate a score based on preoperative characteristics and predictive of the individual probability of allogeneic erythrocyte transfusion in patients undergoing elective thoracolumbar spine surgery. METHODS:Two hundred thirty consecutive patients were retrospectively included ov...

journal_title：Anesthesiology

authors： Lenoir B,Merckx P,Paugam-Burtz C,Dauzac C,Agostini MM,Guigui P,Mantz J

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Buprenorphine, a partial μ-opioid receptor agonist and κ-opioid receptor antagonist, is an effective analgesic. The effects of buprenorphine on sleep have not been well characterized. This study tested the hypothesis that an antinociceptive dose of buprenorphine decreases sleep and decreases adenosine concen...

journal_title：Anesthesiology

authors： Gauthier EA,Guzick SE,Brummett CM,Baghdoyan HA,Lydic R

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The authors explored the database of the first International Study of Postoperative Cognitive Dysfunction study to specify the domains of cognitive function that were most vulnerable and to determine the pattern of deterioration in patients with preoperative cognitive impairment. METHODS:One thousand two hu...

journal_title：Anesthesiology

authors： Silverstein JH,Steinmetz J,Reichenberg A,Harvey PD,Rasmussen LS

更新日期：2007-03-01 00:00:00

abstract：:Arterial tonometry is a technique used to measure arterial blood pressure noninvasively. The authors developed a new tonometer system containing an array of 15 piezoresistive pressure transducers, a mechanical positioning system, signal conditioning and multiplexing electronics, and a display and control console. The ...

journal_title：Anesthesiology

authors： Kemmotsu O,Ueda M,Otsuka H,Yamamura T,Winter DC,Eckerle JS

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Sevoflurane is commonly used for cervical cancer surgery, but its effect on cervical cancer cell biology remains unclear. This mechanistic study explores how sevoflurane affects the proliferation and metastatic potential of immortalized cervical cancer cell lines. METHODS:Cultured cervical cancer Caski and ...

journal_title：Anesthesiology

authors： Zhang W,Sheng B,Chen S,Zhao H,Wu L,Sun Y,Cui J,Zhu X,Ma D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The mechanisms that underlie the supraspinal central nervous system effects of systemic lidocaine are poorly understood and not solely explained by Na(+) channel blockade. Among other potential targets is the hyperpolarization-activated cation current, I(h), which is blocked by lidocaine in peripheral neuron...

journal_title：Anesthesiology

authors： Putrenko I,Schwarz SK

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury incidence remains the leading cause of posttransfusion mortality. The etiology may be related to leukocyte antibodies or biologically active compounds in transfused plasma, injuring susceptible recipient's lungs. The authors have hypothesized that transfusion could have ...

journal_title：Anesthesiology

authors： Feiner JR,Gropper MA,Toy P,Lieberman J,Twiford J,Weiskopf RB

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:During laparoscopic surgery utilizing carbon dioxide as the insufflating agent, nitrous oxide will diffuse into the peritoneal cavity if it is used as part of the anesthetic. Bowel perforation and the subsequent release of volatile bowel gas could create a explosion hazard. METHODS:Two related studies were ...

journal_title：Anesthesiology

authors： Neuman GG,Sidebotham G,Negoianu E,Bernstein J,Kopman AF,Hicks RG,West ST,Haring L

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Cardiac protection by volatile anesthetic-induced preconditioning and ischemic preconditioning have similar signaling pathways. Recently, it was reported that augmentation of protein modified with O-linked β-N-acetylglucosamine (O-GlcNAc) contributes to cardiac protection. This study investigated the role of...

journal_title：Anesthesiology

authors： Hirose K,Tsutsumi YM,Tsutsumi R,Shono M,Katayama E,Kinoshita M,Tanaka K,Oshita S

更新日期：2011-11-01 00:00:00

abstract：:Five healthy, nonpregnant volunteers were studied before and after induction of lumbar epidural anesthesia to determine the cause of central hypothermia during epidural anesthesia. Cutaneous heat loss was measured from 10 area-weighted sites using thermal flux transducers. Oxygen consumption was measured and converted...

journal_title：Anesthesiology

authors： Hynson JM,Sessler DI,Glosten B,McGuire J

更新日期：1991-04-01 00:00:00