Effects of intravenous or subarachnoid morphine on cerebral and spinal cord hemodynamics and antagonism with naloxone in dogs.

abstract：:The effects of subparalytic doses of succinylcholine and d-tubocurarine on epinephrine-induced cardiac arrhythmias during halothane anesthesia were evaluated in dogs. Succinylcholine markedly increased (P is less than .05) the arrhythmogenicity of epinephrine and d-tubocurarine slightly decreased (P is less than .05) ...

journal_title：Anesthesiology

authors： Tucker WK,Munson ES

更新日期：1975-01-01 00:00:00

abstract：:The treatment of venous air embolism by aspiration from central venous catheters is well established. However, some anesthesiologists prefer to use a pulmonary artery catheter to monitor patients undergoing a neurosurgical procedure in the sitting position. While offering certain advantages, pulmonary artery catheters...

journal_title：Anesthesiology

authors： Bowdle TA,Artru AA

更新日期：1988-01-01 00:00:00

abstract：:We recorded the frequency with which anesthesia personnel came in contact with patient body fluids in order to provide an empirical basis for the recommendation of relevant precautions. Anesthesia personnel completed a questionnaire when performing a range of standardized procedures. The rate of contact with blood was...

journal_title：Anesthesiology

authors： Kristensen MS,Sloth E,Jensen TK

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:The neural mechanisms underlying the modulation of pain perception by hypnosis remain obscure. In this study, we used positron emission tomography in 11 healthy volunteers to identify the brain areas in which hypnosis modulates cerebral responses to a noxious stimulus. METHODS:The protocol used a factorial ...

journal_title：Anesthesiology

authors： Faymonville ME,Laureys S,Degueldre C,DelFiore G,Luxen A,Franck G,Lamy M,Maquet P

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Xenon has been shown to be neuroprotective in several models of in vitro and in vivo neuronal injury. However, its putative neuroprotective properties have not been evaluated in focal cerebral ischemia. The purpose of this study was to determine if xenon offers neuroprotection in a mouse model of middle cere...

journal_title：Anesthesiology

authors： Homi HM,Yokoo N,Ma D,Warner DS,Franks NP,Maze M,Grocott HP

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Neuronal voltage-dependent potassium (K) currents are crucial for various cellular functions, such as the integration of temporal information in the central nervous system. Data for the effects of intravenous anesthetics on human neuronal K currents are limited. It was the authors' aim to evaluate the concen...

journal_title：Anesthesiology

authors： Friederich P,Urban BW

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:General anesthetics reduce neuronal death caused by focal cerebral ischemia in rodents and by in vitro ischemia in cultured neurons and brain slices. However, in intact animals, the protective effect may enhance neuronal survival for only several days after an ischemic injury, possibly because anesthetics pr...

journal_title：Anesthesiology

authors： Sullivan BL,Leu D,Taylor DM,Fahlman CS,Bickler PE

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Despite decreasing cardiac events, perioperative beta-blockade also increases perioperative stroke and mortality. Major bleeding and/or hypotension are independently associated with these outcomes. To investigate the hypothesis that beta-blockade limits the cardiac reserve to compensate for acute surgical an...

journal_title：Anesthesiology

authors： Beattie WS,Wijeysundera DN,Karkouti K,McCluskey S,Tait G,Mitsakakis N,Hare GM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A high proportion of patients having cardiac bypass surgery receive erythrocyte transfusions. Decisions about when to transfuse patients having surgery for coronary artery disease may impact on erythrocyte utilization and patient morbidity and mortality. There are no published data about the factors that inf...

journal_title：Anesthesiology

authors： Shehata N,Wilson K,Mazer CD,Tomlinson G,Streiner D,Hebert P,Naglie G

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Chronic pain models are commonly defined as either nerve-injury or inflammation models, but recent work suggests inflammatory processes are important in nerve injury-induced pain. METHODS:In the rat spinal nerve ligation model, the authors examined effects of systemic corticosteroid triamcinolone acetonide ...

journal_title：Anesthesiology

authors： Li H,Xie W,Strong JA,Zhang JM

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Days alive and out of hospital is a potentially useful patient-centered quality measure for perioperative care in adult surgical patients. However, there has been very limited prior validation of this endpoint with respect to its ability to capture differences in patient-level risk factor profiles and longer...

journal_title：Anesthesiology

authors： Jerath A,Austin PC,Wijeysundera DN

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Povidone iodine (PI) solution is used commonly for skin disinfection before epidural and spinal anesthesia. Although there have been reports indicating the presence of microbial contaminants in PI solution, none have evaluated the prevalence of PI contamination. The aims of this study were to assess the freq...

journal_title：Anesthesiology

authors： Birnbach DJ,Stein DJ,Murray O,Thys DM,Sordillo EM

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The impact of intraoperative ventilation on postoperative pulmonary complications is not defined. The authors aimed at determining the effectiveness of protective mechanical ventilation during open abdominal surgery on a modified Clinical Pulmonary Infection Score as primary outcome and postoperative pulmona...

journal_title：Anesthesiology

authors： Severgnini P,Selmo G,Lanza C,Chiesa A,Frigerio A,Bacuzzi A,Dionigi G,Novario R,Gregoretti C,de Abreu MG,Schultz MJ,Jaber S,Futier E,Chiaranda M,Pelosi P

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The authors' objective was to assess the role of protein kinase C (PKC) and nitric oxide synthase (NOS) in mediating the effects of propofol on diabetic cardiomyocyte contractility, intracellular free Ca2+ concentration ([Ca2+]i), and myofilament Ca2+ sensitivity. METHODS:Freshly isolated ventricular myocyt...

journal_title：Anesthesiology

authors： Wickley PJ,Shiga T,Murray PA,Damron DS

更新日期：2006-05-01 00:00:00

abstract：:In late 1846, following his successful public demonstrations of surgical anesthesia, Boston dentist William T. G. Morton selected Letheon as the commercial name for the ether-based "preparation" he had used to produce insensibility to pain. We have not identified a first-hand account of the coinage of Letheon. Althoug...

journal_title：Anesthesiology

authors： Haridas RP,Gionfriddo M,Bause GS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics such as isoflurane are widely used in clinical and research contexts. Concerns have been raised that the effects of these drugs on the central nervous system may result in long-term impairment after surgery or general anesthesia. Hence, this study aimed to detect how different isoflurane...

journal_title：Anesthesiology

authors： Valentim AM,Di Giminiani P,Ribeiro PO,Rodrigues P,Olsson IA,Antunes LM

更新日期：2010-11-01 00:00:00

abstract：:Complications after major surgery are a leading cause of morbidity and mortality. The etiology of postoperative complications is complex, but poor cardiorespiratory reserve appears to be a key factor. There is increasing interest in the use of central and mixed venous oxygen saturation to guide therapeutic interventio...

journal_title：Anesthesiology

authors： Shepherd SJ,Pearse RM

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The results of sevoflurane biotransformation (fluoromethyl-1,1,1,3,3,3,-hexafluoro-2-propyl ether) to inorganic fluoride have been examined. However, these investigations have lacked a simplified assay for determining the primary organic metabolite, hexafluoroisopropanol. Previous attempts have involved exte...

journal_title：Anesthesiology

authors： Morgan SE,Frink EJ,Gandolfi AJ

更新日期：1994-01-01 00:00:00

abstract：:The thermoregulatory threshold for vasoconstriction has been studied in infants and children given isoflurane, but not in those given halothane anesthesia. More importantly, the effect of vasoconstriction on central temperature in pediatric patients remains unknown. Also unknown is the effect of caudal analgesia on va...

journal_title：Anesthesiology

authors： Bissonnette B,Sessler DI

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:With percutaneous recordings of muscle nerve sympathetic activity (MSA), it is possible to study interactions between the autonomic nervous system and anesthetics. This study describes the effects of propofol infusion both before and during microlaryngoscopy. METHODS:Nine patients participated. MSA was reco...

journal_title：Anesthesiology

authors： Sellgren J,Ejnell H,Elam M,Pontén J,Wallin BG

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Chronic neck pain after whiplash injury is caused by cervical zygapophysial joints in 50% of patients. Diagnostic blocks of nerves supplying the joints are performed using fluoroscopy. The authors' hypothesis was that the third occipital nerve can be visualized and blocked with use of an ultrasound-guided te...

journal_title：Anesthesiology

authors： Eichenberger U,Greher M,Kapral S,Marhofer P,Wiest R,Remonda L,Bogduk N,Curatolo M

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Because the nuclear factor-κB (NF-κB) coupled pathway is believed to amplify inflammation prevailing in sepsis, the authors tested the hypotheses that the insertion-deletion polymorphism (-94ins/delATTG) (1) alters nuclear translocation of nuclear factor-κB and activator protein-1 (NF-κB1) in monocytes after...

journal_title：Anesthesiology

authors： Adamzik M,Schäfer S,Frey UH,Becker A,Kreuzer M,Winning S,Frede S,Steinmann J,Fandrey J,Zacharowski K,Siffert W,Peters J,Hartmann M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers improve cognitive function. The authors therefore tested the primary hypothesis that preoperative use of angiotensin inhibitors is associated with less delirium in critical care patients. Post hoc, the association between postoperativ...

journal_title：Anesthesiology

authors： Farag E,Liang C,Mascha EJ,Argalious MY,Ezell J,Maheshwari K,Esa WAS,Troianos CA,Sessler DI

更新日期：2020-07-01 00:00:00

abstract：:The effect of physostigmine on the loss of consciousness and respiratory depression induced in rabbits by flunitrazepam, 1 mg/kg, was studied to demonstrate whether the restoration of consciousness and respiration rate results from an increase in central cholinergic activity or from an interference by physostigmine wi...

journal_title：Anesthesiology

authors： Vatashsky E,Beilin B,Razin M,Weinstock M

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Acute pancreatitis has been linked to intestinal barrier dysfunction and systemic inflammatory response with high mortality. Thoracic epidural analgesia improves intestinal perfusion. The authors hypothesized that thoracic epidural analgesia influences microcirculation injury, inflammatory response, and outc...

journal_title：Anesthesiology

authors： Freise H,Lauer S,Anthonsen S,Hlouschek V,Minin E,Fischer LG,Lerch MM,Van Aken HK,Sielenkämper AW

更新日期：2006-08-01 00:00:00

abstract：:To study the cerebral protective effects of hypothermia in arterial hypoxia, anesthetized (70% N2O), mechanically ventilated rats were cooled to a body temperature of 27 C. Hypoxia was induced by decreasing the oxygen content in the inspired gas mixture either to 6-7 per cent or to 2.5-3 per cent. This reduced mean Pa...

journal_title：Anesthesiology

authors： Carlsson C,Hägerdal M,Siesjö BK

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Lamotrigine inhibits glutamate release through the preferential blockade of voltage-dependent Na+ channels. In contrast, morphine reduces release of excitatory amino acids through the activation of opioid receptors and also inhibits tetrodotoxin-resistant Na+ channels on peripheral afferent neurons. The curr...

journal_title：Anesthesiology

authors： Argüelles CF,Torres-López JE,Granados-Soto V

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The number of pregnancy-related deaths and severe maternal complications continues to rise in the United States, and the quality of obstetrical care across U.S. hospitals is uneven. Providing hospitals with performance feedback may help reduce the rates of severe complications in mothers and their newborns. ...

journal_title：Anesthesiology

authors： Glance LG,Hasley S,Glantz JC,Stevens TP,Faden E,Kreso MA,Pyne SG,Wissler RN,Fichter J,Gloff MS,Dick AW

更新日期：2019-08-01 00:00:00

abstract：:Dexmedetomidine (DMED) is a highly selective centrally acting alpha 2-adrenergic agonist thought to provide significant sedation without appreciable ventilatory effects. This double-blind, placebo-controlled experiment evaluated four dose levels of DMED (0.25, 0.5, 1.0, and 2.0 micrograms/kg intravenously over 2 min) ...

journal_title：Anesthesiology

authors： Belleville JP,Ward DS,Bloor BC,Maze M

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:The current study was designed to test the hypothesis that the fibromyalgia survey criteria would be directly associated with increased opioid consumption after hysterectomy even when accounting for other factors previously described as being predictive for acute postoperative pain. METHODS:Two hundred eigh...

journal_title：Anesthesiology

authors： Janda AM,As-Sanie S,Rajala B,Tsodikov A,Moser SE,Clauw DJ,Brummett CM

更新日期：2015-05-01 00:00:00