当前位置： SCI文献检索 > DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE期刊下所有文献 > Comparative in vitro activities of ertapenem against aerobic and facultative bacterial pathogens from patients with complicated skin and skin structure infections.

Comparative in vitro activities of ertapenem against aerobic and facultative bacterial pathogens from patients with complicated skin and skin structure infections.

Abstract：

:This study compared the in vitro activities of ertapenem (Merck & Co., Inc.), ceftriaxone, amoxicillin-clavulanate, and piperacillin-tazobactam against 518 aerobic and facultative bacterial pathogens isolated from 340 patients with complicated skin and skin structure infections. Ciprofloxacin was also tested against Gram-negative isolates. Gram-positive cocci accounted for 68.1% of the aerobic bacteria; Staphylococcus aureus was the most common isolate (45.6%). The ertapenem MIC was < or = 2 microg/ml for 80.9% of isolates and > or = 8 microg/ml for 16.2% (including isolates of enterococci, methicillin-resistant S. aureus, Pseudomonas aeruginosa, and other nonfermentative Gram-negative bacteria). Against methicillin-susceptible S. aureus, ertapenem had the most potent activity. Ertapenem was the most active drug against Enterobacteriaceae (100% susceptible), whereas amoxicillin-clavulanate was least active (66% susceptible). Piperacillin-tazobactam was the most active drug against P. aeruginosa (100% susceptible), followed by ciprofloxacin (87% susceptible). In summary, ertapenem was highly active in vitro against many aerobic and facultative bacterial pathogens commonly recovered from patients with complicated skin and skin structure infections.

journal_name

Diagn Microbiol Infect Dis

journal_title

Diagnostic microbiology and infectious disease

authors

Pelak BA,Bartizal K,Woods GL,Gesser RM,Motyl M

doi

10.1016/s0732-8893(02)00387-5

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

129-33

issue

2

eissn

0732-8893

issn

1879-0070

pii

S0732889302003875

journal_volume

43

pub_type

杂志文章

相关文献

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE文献大全
  • Diagnostic performance of a new automated heterophile antibody test in adults and children.

    abstract：:Epstein-Barr virus serologic profiles were obtained from 618 patients using an automated platform, including the new BioPlex heterophile assay. When compared with 2 IgM viral capsid antigen (VCA) assays and a predicate heterophile assay, the BioPlex heterophile assay was more likely to be associated with serologic pat...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2008.02.016

    authors： Klutts JS,Wu AH,Smith A,Yen-Lieberman B,Gronowski AM

    更新日期：2008-07-01 00:00:00

  • Emergence of metallo-β-lactamases in Enterobacteriaceae from Argentina.

    abstract：:Carbapenem susceptibility in Enterobacteriaceae (M9921, M9959) revealed the presence of MBLs bla(VIM-2) (M9959) and bla(IMP-8) (M9921), both as first cassettes of class-1-integrons. ESBL bla(PER-2) was detected in both strains and M9921 also harboured qnrB10, aac(6')-Ib and aac(6')-Ib-cr. This is the first report of M...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2010.08.025

    authors： Gomez S,Rapoport M,Togneri A,Viegas-Caetano J,Faccone D,Corso A,Petroni A,Pasteran F

    更新日期：2011-01-01 00:00:00

  • Evaluation of rapid culture centrifugation method for adenovirus detection in stools.

    abstract：:Routine laboratory testing for adenovirus (Adv) requires a procedure that is rapid and reliable, especially for samples from children and immunosuppressed patients, when diarrhea may signal the onset of severe gastrointestinal disorders. An improved culture technique for Adv isolation, using centrifugation step of 24-...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(95)00271-5

    authors： Durepaire N,Ranger-Rogez S,Denis F

    更新日期：1996-01-01 00:00:00

  • Characterization of novel VIM carbapenemase, VIM-38, and first detection of GES-5 carbapenem-hydrolyzing β-lactamases in Pseudomonas aeruginosa in Turkey.

    abstract：:Pseudomonas aeruginosa isolates were collected form a Turkish hospital. Antimicrobial susceptibility was performed using the Vitek 2 Compact system, and 24 isolates were categorized as multidrug resistant (n = 18), extensively-drug resistant (n = 5), or pan-drug resistant (n = 1). PCR and DNA sequence analysis reveale...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2013.12.003

    authors： Iraz M,Duzgun AO,Cicek AC,Bonnin RA,Ceylan A,Saral A,Nordmann P,Sandalli C

    更新日期：2014-03-01 00:00:00

  • Salmonella prosthetic valve endocarditis.

    abstract：:Four cases of Salmonella prosthetic valve endocarditis have been reported previously in the English medical literature (Fraser et al. 1967; Yamamoto et al., 1974; Shanson et al., 1977; Bassa et al., 1989). This report describes a fifth case in a 62-year-old woman who developed tricuspid valve endocarditis after an epi...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章,评审

    doi：10.1016/0732-8893(92)90124-c

    authors： Choo PW,Gantz NM,Anderson C,Maguire JH

    更新日期：1992-03-01 00:00:00

  • The effect of fecal turbidity on norovirus detection by reverse transcriptase polymerase chain reaction.

    abstract：:A 10-min fecal preparation results in greater specimen turbidity than a 45-min protocol, but reverse transcriptase polymerase chain reaction (RT-PCR) norovirus test sensitivity is essentially the same. Feces processed so that particle size does not exceed approximately 560 nm do not display greater norovirus RT-PCR in...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2008.08.006

    authors： Witlox KJ,Karapanagiotidis T,Bruggink LD,Marshall JA

    更新日期：2010-02-01 00:00:00

  • In vitro activity of cefoperazone/sulbactam and other antimicrobials against anaerobic bacteria.

    abstract：:Sulbactam inhibits the hydrolytic activity of several, clinically important beta-lactamases including those produced by anaerobic bacteria. This study was undertaken to determine the effect of sulbactam on the activity of cefoperazone against 250 anaerobic bacteria including 174 isolates belonging to the Bacteroides f...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(90)90054-y

    authors： D'Amato RF,Hochstein L,Frankel H

    更新日期：1990-01-01 00:00:00

  • Thermosensitive transfer of antimicrobial resistances and citrate utilization and cotransfer of hydrogen sulfide production from an Escherichia coli isolate.

    abstract：:A hydrogen-sulfide producing, citrate-positive strain of Escherichia coli isolated from urinary tract infection was found to be resistant to chloramphenicol (Cm), tetracycline (Tc), streptomycin (Sm), trimethoprim (Tmp), sulfamethoxazole (Smx), and cotrimoxazole (Tmp/Smx). The strain contained 7 plasmids of molecular ...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(96)00027-2

    authors： Harnett N,Mangan L,Brown S,Krishnan C

    更新日期：1996-04-01 00:00:00

  • Epidemiology and outcome of multiple-species candidemia at a tertiary care center between 2004 and 2007.

    abstract：:The incidence of multiple-species candidemia (MSC) among cases of candidemia ranges between 2.8% and 8.0%. We sought to study the epidemiology and outcome of MSC at a tertiary care center. A retrospective analysis of MSC episodes occurring between 2004 and 2007 was performed. MSC was defined as > or =2 different Candi...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2009.03.010

    authors： Nace HL,Horn D,Neofytos D

    更新日期：2009-07-01 00:00:00

  • Differentiation of mycobacteria in sputa by duplex polymerase chain reaction for mycobacterial hsp65 gene.

    abstract：:Early differentiation of mycobacteria in sputa is crucial. This study was set to evaluate the usefulness of a newly developed duplex polymerase chain reaction (PCR) for hsp65 gene-based method in differentiating mycobacteria in sputum with a positive acid-fast bacilli (AFB) smear before culturing. One hundred forty-se...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2008.05.013

    authors： Kim BJ,Park JH,Lee SA,Kim H,Cha CY,Kook YH,Kim EC,Joo SI,Lee JS,Yim JJ

    更新日期：2008-10-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus carrying the new mecC gene--a meta-analysis.

    abstract：:In 2011, a new mecA gene homolog, named mecC gene, was found in isolates from both humans and animals. The discovery of methicillin-resistant Staphylococcus aureus (MRSA) carrying the mecC gene has caused speculations about the origin, epidemiology, and impact of these isolates. The objective of this work is to perfor...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.diagmicrobio.2015.10.014

    authors： Diaz R,Ramalheira E,Afreixo V,Gago B

    更新日期：2016-02-01 00:00:00

  • Role of quantitative CSF microscopy to predict culture status and outcome in HIV-associated cryptococcal meningitis in a Brazilian cohort.

    abstract：:This retrospective study aimed to evaluate the clinical, laboratory, and quantitative cerebrospinal fluid (CSF) cryptococcal cell counts for associations with in-hospital outcomes of HIV-infected patients with cryptococcal meningitis. Ninety-eight HIV-infected adult patients with CSF culture-proven cryptococcal mening...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2012.01.014

    authors： Vidal JE,Gerhardt J,Peixoto de Miranda EJ,Dauar RF,Oliveira Filho GS,Penalva de Oliveira AC,Boulware DR

    更新日期：2012-05-01 00:00:00

  • Influenza B false-positive results by rapid molecular tests Alere™ i Influenza A&B 2 in France.

    abstract：:The Alere-i™ Influenza A&B (Abbott), a nicking endonuclease amplification reaction test, has recently been improved in order to deliver results in a few minutes. Our field observation highlights two problems with this new version: improper interpretation of a test as valid despite improper reagent hydration and falsel...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2019.03.002

    authors： Otto MP,Toyer AL,Poggi C,Janvier F

    更新日期：2019-08-01 00:00:00

  • Multicenter evaluation of the Verigene Gram-negative blood culture nucleic acid test for rapid detection of bacteria and resistance determinants in positive blood cultures.

    abstract：:The Verigene Gram-Negative Blood Culture Nucleic Acid Test (BC-GN) is a microarray-based assay that enables rapid detection of 9 common Gram-negative bacteria and 6 resistance determinants directly from positive blood cultures. We compared the performance of BC-GN with currently used automated systems, testing 141 cli...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.diagmicrobio.2015.08.004

    authors： Uno N,Suzuki H,Yamakawa H,Yamada M,Yaguchi Y,Notake S,Tamai K,Yanagisawa H,Misawa S,Yanagihara K

    更新日期：2015-12-01 00:00:00

  • In vitro susceptibility and synergy studies of Aspergillus species to conventional and new agents.

    abstract：:In vitro susceptibility data using a macrodilution broth method on greater than 100 isolates of Aspergillus spp. are presented. For amphotericin B (Amp B) (n = 105), 67% had minimum inhibitory concentrations (MICs) less than or equal to 2 micrograms/ml, and 90% had MICs less than or equal to 4 micrograms/ml; for 5-flu...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(92)90053-v

    authors： Denning DW,Hanson LH,Perlman AM,Stevens DA

    更新日期：1992-01-01 00:00:00

  • Identification of Staphylococcus spp. and detection of mecA by an oligonucleotide array.

    abstract：:Phenotypic identification of coagulase-negative staphylococci (CoNS) is difficult and many staphylococcal species carry mecA. This study developed an array that was able to detect mecA and identify 30 staphylococcal species by targeting the internal transcribed spacer regions. A total of 129 target reference strains (...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2016.06.003

    authors： Han HW,Chang HC,Chang TC

    更新日期：2016-09-01 00:00:00

  • Rapid detection of high-risk Enterococcus faecium clones by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

    abstract：:We aimed to explore the potential of matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for early identification of dominant Enterococcus faecium (Efm) clones involved in human infections. Well-characterized Efm isolates (n=77), analyzed by pulsed-field gel electrophoresis and ...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2016.12.007

    authors： Freitas AR,Sousa C,Novais C,Silva L,Ramos H,Coque TM,Lopes J,Peixe L

    更新日期：2017-04-01 00:00:00

  • Evaluation of a rapid antigen detection point-of-care test for respiratory syncytial virus and influenza in a pediatric hospitalized population in the Netherlands.

    abstract：:This pilot study evaluates the diagnostic performance of Sofia RSV Fluorescent Immunoassay Analyzer (FIA) and Sofia Influenza A + B FIA for rapid detection of respiratory syncytial virus and influenza A and B. Sofia had a lower-than-expected sensitivity for all viruses and a high rate of false-positive results for inf...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2014.08.010

    authors： Bruning AH,van Dijk K,van Eijk HW,Koen G,van Woensel JB,Kruisinga FH,Pajkrt D,Wolthers KC

    更新日期：2014-12-01 00:00:00

  • Low-level resistance to glycopeptides amongst staphylococcus species: surveillance in a university hospital and evaluation of a vancomycin screening agar.

    abstract：:The prevalence of low-level resistance to glycopeptides (teicoplanin MIC > or = 8 microg/mL and vancomycin MIC > or = 4 microg/mL) among staphylococci was investigated over a 15 month period. A total of 2,279 isolates (1,519 S. aureus, 760 coagulase-negative staphylococcus (CNS)) were screened using inoculum of 10(6) ...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/s0732-8893(01)00302-9

    authors： Park YJ,Jun Park J,Lee SO,Oh EJ,Kee Kim B

    更新日期：2001-11-01 00:00:00

  • Evaluation of three Copan viral transport systems for the recovery of cultivatable, clinical virus isolates.

    abstract：:Three Copan viral transport media (VTM) were compared to the BBL Viral Culturette and Micro Test M4 systems for their ability to maintain the viability of clinical strains of enterovirus, herpes simplex virus, adenovirus and parainfluenza virus. VTM were inoculated, incubated up to 72 h at both 4 degrees C and 22 degr...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/s0732-8893(02)00541-2

    authors： Dunn JJ,Billetdeaux E,Skodack-Jones L,Carroll KC

    更新日期：2003-03-01 00:00:00

  • Clinical, immunological and microbiological predictors of poor outcome in Clostridium difficile infection.

    abstract：BACKGROUND:Clostridium difficile infection (CDI) causes increased morbidity and mortality. Clinical data cannot clearly predict poor CDI outcome. Data on the value of microbiological predictors is scarce. OBJECTIVE:To identify early predictors of poor outcome of CDI. METHODS:We prospectively included patients with CD...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2017.05.005

    authors： Reigadas E,Alcalá L,Marín M,Martín A,Bouza E

    更新日期：2017-08-01 00:00:00

  • Antimicrobial activities of doripenem and other carbapenems against Pseudomonas aeruginosa, other nonfermentative bacilli, and Aeromonas spp.

    abstract：:The in vitro activity of doripenem against prevalent nonfermentative Gram-negative bacilli and Aeromonas spp. was evaluated. The collection comprised 14979 nonduplicate clinical isolates submitted during a global Doripenem Surveillance Program conducted from 2003 through 2007. Susceptibility tests were performed using...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2009.01.026

    authors： Castanheira M,Jones RN,Livermore DM

    更新日期：2009-04-01 00:00:00

  • Vibrio parahaemolyticus (Kanagawa-negative) wound infection in a hospital dietary employee.

    abstract：:Vibrio parahaemolyticus is an estuarine bacterium that is a major cause of gastroenteritis worldwide. Occasionally, this organism has also been shown to be the causative agent of wound infections. In almost all cases of gastrointestinal disease only strains that produce hemolysin ("Kanagawa-positive") are implicated. ...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(88)90059-4

    authors： Sautter RL,Taylor JS,Oliver JD,O'Donnell C

    更新日期：1988-01-01 00:00:00

  • Frequency of occurrence and antimicrobial susceptibility of bacteria isolated from patients hospitalized with bloodstream infections in United States medical centers (2015-2017).

    abstract：:The frequency and antimicrobial susceptibility of organisms causing bloodstream infections in the United States were evaluated by consecutively collecting (1/patient) 9210 bacterial isolates from 33 US medical centers in 2015-2017. Isolates were susceptibility tested by reference broth microdilution methods. Whole gen...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.diagmicrobio.2019.06.002

    authors： Sader HS,Castanheira M,Streit JM,Flamm RK

    更新日期：2019-11-01 00:00:00

  • Partial comparison of the NxTAG Respiratory Pathogen Panel Assay with the Luminex xTAG Respiratory Panel Fast Assay V2 and singleplex real-time polymerase chain reaction for detection of respiratory pathogens.

    abstract：:In this study, 185 nasopharyngeal swabs were tested to compare the sensitivity and specificity of the Luminex NxTAG (NxTAG) Respiratory Pathogen Panel (RPP) Assay with those of the Luminex Respiratory Virus Panel (RVP) Fast Assay v2 and singleplex real-time polymerase chain reaction (PCR). The NxTAG Assay identified a...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2016.06.018

    authors： Esposito S,Scala A,Bianchini S,Presicce ML,Mori A,Sciarrabba CS,Fior G,Principi N

    更新日期：2016-09-01 00:00:00

  • Quantification and identification of polyomavirus DNA in blood and urine of renal transplant recipients.

    abstract：:A cohort of 201 kidney transplant recipients (KTR) including 7 patients with evidence of renal function deterioration (as defined by creatinine levels >20% over baseline values) was analyzed for polyomavirus DNA in blood and urine samples by a new quantitative polymerase chain reaction method. Of 201 patients, 14 (6.9...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2006.08.006

    authors： Baldanti F,Fogazzi GB,Furione M,Saglimbeni L,Rovida F,Gatti M,Paolucci S,Tarantino A,Gerna G

    更新日期：2007-03-01 00:00:00

  • A cocktail of affinity-purified antibodies reactive with diagnostically useful mycobacterial antigens ES-31, ES-43, and EST-6 for detecting the presence of Mycobacterium tuberculosis.

    abstract：:A cocktail of affinity-purified antibodies against diagnostically useful Mycobacterium tuberculosis H37Ra excretory-secretory protein antigens ES-31, ES-43, and EST-6 was explored for detection of circulating free and immune-complexed (IC) antigen in sera of patients with confirmed tuberculosis (TB) by sandwich enzyme...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2005.10.021

    authors： Harinath BC,Kumar S,Roy SS,Hirudkar S,Upadhye V,Shende N

    更新日期：2006-05-01 00:00:00

  • Change in the clinical antifungal sensitivity profile of Aspergillus flavus induced by azole and a benzimidazole fungicide exposure.

    abstract：:The study evaluated the change in the clinical antifungal sensitivity profile of A. flavus strains after exposure to azole and benzimidazole fungicide. Exposure to fungicide altered the sensitivity profile for the antifungal itraconazole, voriconazole and posaconazole. This change was characterized by an increase in t...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/j.diagmicrobio.2019.05.019

    authors： Meireles LM,de Araujo ML,Endringer DC,Fronza M,Scherer R

    更新日期：2019-10-01 00:00:00

  • Comparison of fluconazole minimum inhibitory concentrations in three different formulations of RPMI-1640.

    abstract：:This study aimed to compare the susceptibilities of fluconazole, obtained in two laboratories, using three RPMI-1640 formulations (manufacturers') and inhibition standards (80%). A total of 39 selected Candida species (in vitro susceptible and resistant) and Cryptococcus neoformans isolates were tested in each medium ...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(94)90097-3

    authors： Espinel-Ingroff A,Steele-Moore L

    更新日期：1994-10-01 00:00:00

  • Effect of treatment of shell vial cell cultures with dimethyl sulfoxide and dexamethasone and age of MRC-5 monolayers for detection of cytomegalovirus.

    abstract：:Pretreatment of MRC-5 cell monolayers in commercially prepared shell vials with 1% dimethyl sulfoxide (DMSO) and 10(-5) mol/L dexamethasone (DEX) was evaluated. Preliminary experiments indicated enhanced infectivity of AD-169 for pretreated MRC-5 cells in shell vials of ages 9 and 16 days. Compared with untreated shel...

    journal_title：Diagnostic microbiology and infectious disease

    pub_type： 杂志文章

    doi：10.1016/0732-8893(90)90052-w

    authors： Fedorko DP,Ilstrup DM,Smith TF

    更新日期：1990-01-01 00:00:00