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Lyophilized aqueous based polymer matrices for transdermal delivery of captopril.

Abstract：

:Transdermal system(s) bearing captopril were developed using a low temperature casting method and aqueous based polymers viz., eudragit RL-100 and polyvinyl pyrrolidone (PVP). The developed system(s) were subjected to an in vitro characterization study. The results were compared with the transdermal systems of the same composition prepared at room temperature. The study revealed that the system(s) prepared using the low temperature casting method performed better in comparison to those prepared at room temperature. The developed system(s) followed zero order release kinetics.

journal_name

J Dermatol Sci

journal_title

Journal of dermatological science

authors

Dubey BK,Katare OP,Singh R,Jain SK

doi

10.1016/0923-1811(95)00403-f

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

191-5

issue

3

eissn

0923-1811

issn

1873-569X

pii

092318119500403F

journal_volume

10

pub_type

杂志文章

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