Sleep and breathing in Prader-Willi syndrome.

Abstract:

:Prader-Willi syndrome (PWS) is a genetic disorder, with hypotonia being the predominant feature in infancy, and developmental delay, obesity, and behavioral problems becoming more prominent in childhood and adolescence. Children with this disorder frequently suffer from excessive daytime sleepiness and have a primary abnormality of the circadian rhythm of rapid eye movement sleep. They also have primary abnormal ventilatory responses to hypoxia and hypercapnia, and these abnormalities may be exacerbated by obesity. Children with PWS are at risk of a variety of abnormalities of breathing during sleep, including obstructive sleep apnea and sleep-related alveolar hypoventilation. Clinical evaluation should include a careful history of sleep-related symptoms and assessment of the upper airway and lung function. Polysomnography should be considered for those with symptoms suggestive of sleep-disordered breathing. Treatment options depend on the underlying problem, but may include behavioral interventions, weight control, adenotonsillectomy, and nocturnal ventilation.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Nixon GM,Brouillette RT

doi

10.1002/ppul.10152

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

209-17

issue

3

eissn

8755-6863

issn

1099-0496

journal_volume

34

pub_type

杂志文章,评审
  • Alveolar data in healthy, awake neonates during spontaneous ventilation: a preliminary investigation.

    abstract::A computerized method for the measurement of alveolar ventilation (VA) and the mean alveolar partial pressures of CO2 and O2 is described and tested in healthy, awake fullterm (FT) newborns and preterm (PT) infants (postnatal age 40 days). This study emphasizes the technical pitfalls generally encountered when dealing...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950050409

    authors: Lagneaux D,Mossay C,Geubelle F,Christiaens G

    更新日期:1988-01-01 00:00:00

  • Apnea and periodic breathing in normal full-term infants during the first twelve months.

    abstract::The pediatric pneumogram is a frequently used tool in the diagnosis and management of apnea during infancy. We analyzed 287 pneumographic recordings from 123 full-term infants (63 males) obtained during the first 12 months of life to establish normative values for apnea, periodic breathing, and bradycardia. The result...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950010409

    authors: Kelly DH,Stellwagen LM,Kaitz E,Shannon DC

    更新日期:1985-07-01 00:00:00

  • Pulmonary manifestations of HIV infection in children.

    abstract::We retrospectively reviewed the spectrum, course, and outcome of pulmonary diseases in 66 children with AIDS, hospitalized between 1982 and 1988, prior to the use of zidovudine. Fifty-two of the 66 (79%) patients developed pulmonary problems. In fifty-two percent of all patients, a pulmonary problem was the first symp...

    journal_title:Pediatric pulmonology

    pub_type: 评论,杂志文章

    doi:10.1002/ppul.1950100402

    authors: Marolda J,Pace B,Bonforte RJ,Kotin NM,Rabinowitz J,Kattan M

    更新日期:1991-01-01 00:00:00

  • Compliance in cystic fibrosis: an examination of infection control guidelines.

    abstract::The goal of this research was to begin the process of evaluating acceptability of infection control (IC) recommendations to CF patients and their families, determine whether compliance with IC guidelines differs from compliance with traditional CF medical treatment with respect to the variables predictive of complianc...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20781

    authors: Masterson T,Wildman BG,Newberry B,Omlor G,Bryson E,Kukay A

    更新日期:2008-05-01 00:00:00

  • Ultrastructural ciliary defects in children with recurrent infections of the lower respiratory tract.

    abstract::One hundred fifty-four children with recurrent or chronic infections of the lower respiratory tract compatible with the diagnosis of primary ciliary dyskinesia (PCD) were evaluated for the presence of ultrastructural ciliary abnormalities. Studies were performed on multiple samples of respiratory mucosa obtained by na...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950100104

    authors: Barlocco EG,Valletta EA,Canciani M,Lungarella G,Gardi C,De Santi MM,Mastella G

    更新日期:1991-01-01 00:00:00

  • Longitudinal changes in lung function during the first three years of premature infants with moderate to severe bronchopulmonary dysplasia.

    abstract::Bronchopulmonary dysplasia (BPD) is a chronic obstructive pulmonary disease of prematurely born infants following prolonged mechanical ventilation and oxygen therapy. Developmental changes in pulmonary function of children with BPD during their early years have been difficult to study. We longitudinally studied maxima...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950110103

    authors: Mallory GB Jr,Chaney H,Mutich RL,Motoyama EK

    更新日期:1991-01-01 00:00:00

  • Passive smoking does not increase hydrogen peroxide (H2O2) levels in exhaled breath condensate in 9-year-old healthy children.

    abstract::Environmental tobacco smoke, also called passive smoking, was shown to have adverse effects on the health of children. Hydrogen peroxide (H2O2) is proposed as a sensitive marker of oxidative injury and inflammatory processes in the airways, being increased in adult active cigarette smokers. We tested whether passive s...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章

    doi:10.1002/ppul.20129

    authors: Doniec Z,Nowak D,Tomalak W,Pisiewicz K,Kurzawa R

    更新日期:2005-01-01 00:00:00

  • Repeatability of bronchial responsiveness to mannitol dry powder in children with asthma.

    abstract::Our objective was to determine the repeatability of bronchial responsiveness to mannitol dry powder (MDP) as an objective marker of asthma in children. MDP challenge was performed in children with stable asthma at the same time of the day on two separate occasions within a week. The test was terminated after a 15% fal...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章

    doi:10.1002/ppul.10378

    authors: Barben J,Roberts M,Chew N,Carlin JB,Robertson CF

    更新日期:2003-12-01 00:00:00

  • Trial of an intervention to reduce passive smoking in infancy.

    abstract::We tested a health education intervention program to reduce passive smoking in infancy. The aim was to develop an instrument for study of tobacco smoke exposure and childhood respiratory illness. One hundred and eighty-four women who had smoked during pregnancy were allocated by month of delivery to an intervention gr...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950030311

    authors: Woodward A,Owen N,Grgurinovich N,Griffith F,Linke H

    更新日期:1987-05-01 00:00:00

  • Acid steatocrit determination is not helpful in cystic fibrosis patients without or with mild steatorrhea.

    abstract:BACKGROUND:Most methods used for the assessment of severe steatorrhea in cystic fibrosis (CF) are sensitive. In fact, the tests show their usefulness in a borderline zone of the results. Yet, the existing data related to acid steatocrit (AS) are still contradictory. Therefore, in the present study we have aimed to asse...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21149

    authors: Walkowiak J,Lisowska A,Blask-Osipa A,Drzymała-Czyz S,Sobkowiak P,Cichy W,Breborowicz A,Herzig KH,Radzikowski A

    更新日期:2010-03-01 00:00:00

  • Prenatal exposure to VOCs and NOx and lung function in preschoolers.

    abstract:BACKGROUND:Several studies have shown that exposure to air pollutants affects lung growth and development and can result in poor respiratory health in early life. METHODS:We included a subsample of 772 Mexican preschoolers whose mothers participated in a Prenatal Omega-3 fatty acid Supplements, GRowth, And Development...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24889

    authors: Gutiérrez-Delgado RI,Barraza-Villarreal A,Escamilla-Núñez MC,Hernández-Cadena L,Cortez-Lugo M,Sly P,Romieu I

    更新日期:2020-08-01 00:00:00

  • Surfactant administration via a thin endotracheal catheter during spontaneous breathing in preterm infants.

    abstract::To systematically review the clinical outcomes of surfactant administration via a thin endotracheal catheter during spontaneous breathing compared with conventional administration involving tracheal intubation, mechanical ventilation (MV), and tracheal extubation, in preterm infants. PubMed, EMBASE, and the Cochrane L...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,评审

    doi:10.1002/ppul.23651

    authors: Wu W,Shi Y,Li F,Wen Z,Liu H

    更新日期:2017-06-01 00:00:00

  • Quantitative chest computerized tomography and FEV1 equally identify pulmonary exacerbation risk in children with cystic fibrosis.

    abstract:BACKGROUND:Chest computerized tomography (CT) scores are associated with the frequency of future pulmonary exacerbations in people with cystic fibrosis (CF). However, cut-off values to identify children with mild lung disease with different risks for frequent future pulmonary exacerbations have not been identified. ME...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/ppul.24144

    authors: Sanders DB,Li Z,Parker-McGill K,Farrell P,Brody AS

    更新日期:2018-10-01 00:00:00

  • Diffuse panbronchiolitis in a 10-year-old boy.

    abstract::Diffuse panbronchiolitis is a progressive fatal respiratory disease of unknown cause seen predominantly in Southeast Asian adults. We report this condition in a 10-year-old child of Korean birth because of the uncommon presentation at this age and the favorable outcome associated with early diagnosis. Our objective wa...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23176

    authors: Weinberger M,Fischer A,Kao S

    更新日期:2015-09-01 00:00:00

  • Reference values of sniff nasal inspiratory pressure in healthy children.

    abstract:OBJECTIVE:To determine reference values of sniff nasal inspiratory pressure (SNIP) in healthy children. METHODS:This cross-sectional observational study included healthy children aged 6 to 11 years of both sexes. The volunteers underwent a pulmonary function test to rule out respiratory disorders. Respiratory muscle s...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24591

    authors: Marcelino AA,Fregonezi GA,Lira MGA,de Oliveira LM,Araújo PRS,Parreira VF,de Andrade AD,Resqueti V

    更新日期:2020-02-01 00:00:00

  • Non invasive positive pressure ventilation in infants with respiratory failure.

    abstract:OBJECTIVE:To determine whether non-invasive positive pressure ventilation (NIPPV) delivered via nasal prongs can alleviate the need for tracheal intubation and invasive ventilation in infants admitted to the pediatric intensive care unit (PICU) with impending respiratory failure, and to find predictive factors for succ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22561

    authors: Cavari Y,Sofer S,Rozovski U,Lazar I

    更新日期:2012-10-01 00:00:00

  • Daily inhaled corticosteroids or montelukast for preschoolers with asthma or recurrent wheezing: A systematic review.

    abstract:BACKGROUND:Most international asthma guidelines recommend that children ≤5 years with asthma or recurrent wheezing be treated with daily low- moderate dose inhaled corticosteroids (ICS) as the preferred controller and leukotriene receptor antagonists (LTRA) as alternative therapy. There is no systematic review comparin...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24176

    authors: Castro-Rodriguez JA,Rodriguez-Martinez CE,Ducharme FM

    更新日期:2018-12-01 00:00:00

  • Asphyxiating tracheal bronchogenic cyst.

    abstract::We report on a 7-month old infant with severe respiratory distress secondary to a paratracheal bronchogenic cyst. Respiratory relief was achieved by transtracheal puncture of the cyst. Surgical removal of the cyst was performed 1 week later because of radiological evidence of reaccumulation of fluid. ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.10408

    authors: De Baets F,Van Daele S,Schelstraete P,Haerynck F,Vermassen F,Broers C

    更新日期:2004-12-01 00:00:00

  • Long-term pulmonary function in esophageal atresia-A case-control study.

    abstract:BACKGROUND:Esophageal atresia (EA) is a congenital anomaly associated with substantial pulmonary morbidity throughout childhood. AIM:The aim of this study was to evaluate pulmonary complications among 59 five to 15-year-old children and adolescents with surgically corrected congenital EA. METHODS:Participants underwe...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23477

    authors: Pedersen RN,Markøw S,Kruse-Andersen S,Qvist N,Gerke O,Husby S,Agertoft L

    更新日期:2017-01-01 00:00:00

  • The bronchodilator effect of a fixed-combination metered aerosol (fenoterol and ipratropium bromide).

    abstract::The fixed-combination metered aerosol lK6 (fenoterol 0.05 mg/puff, ipratropium bromide 0.02 mg/puff--Berodual, Boehringer-Ingelheim Ltd., Ridgefield, Conn.) was administered to 12 children (8 boys, 4 girls) aged 3 1/2 to 6 2/12 years who had extrinsic bronchial asthma. Three forms of administration, each with a differ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950010605

    authors: Berdel D,Kellersmann U

    更新日期:1985-11-01 00:00:00

  • Longitudinal measures of lung function in infants with bronchopulmonary dysplasia.

    abstract::We previously demonstrated that infants with a history of bronchopulmonary dysplasia (BPD) exhibit airflow obstruction and air trapping. The purpose of this study was to assess longitudinal changes in pulmonary function in infants with a history of BPD over the first 3 years of life, and the relationship to somatic gr...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21378

    authors: Filbrun AG,Popova AP,Linn MJ,McIntosh NA,Hershenson MB

    更新日期:2011-04-01 00:00:00

  • Are lower airway or throat cultures predictive of sinus bacteriology in cystic fibrosis?

    abstract::The choice of antibiotics for sinusitis in children with cystic fibrosis (CF) is empirical or based on lower airway cultures, because sinus cultures are difficult to obtain. The aim of this study was to identify the main organisms cultured from CF children with chronic sinusitis, and to evaluate the concordance of con...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20396

    authors: Muhlebach MS,Miller MB,Moore C,Wedd JP,Drake AF,Leigh MW

    更新日期:2006-05-01 00:00:00

  • Elevated vascular endothelial growth factor is correlated with elevated erythropoietin in stable, young cystic fibrosis patients.

    abstract::Angiogenesis is an important mechanism of airway remodeling in lung disease. We previously demonstrated that serum vascular endothelial growth factor (VEGF) is elevated in cystic fibrosis (CF) patients and declines with therapy for pulmonary exacerbation. We hypothesized that VEGF is elevated early in the course of CF...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21428

    authors: Watts KD,McColley SA

    更新日期:2011-07-01 00:00:00

  • The ontogeny of human pulmonary angiotensin-converting enzyme and its aberrant expression may contribute to the pathobiology of bronchopulmonary dysplasia (BPD).

    abstract:INTRODUCTION:The mammalian lung possesses the highest level of angiotensin converting enzyme (ACE) amongst all the organs. ACE is known to generate angiotensin (AT)-II from AT-I and to regulate serum bradykinin level, thereby controlling blood pressure. Recent data, however, indicate a role for ACE derived AT-II in ang...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22911

    authors: Castro EC,Parks WT,Galambos C

    更新日期:2014-10-01 00:00:00

  • Prophylactic antibiotics in cystic fibrosis: a conviction without evidence?

    abstract::Pulmonary infection with Staphylococcus aureus occurs in young children with cystic fibrosis, and may contribute to the cycle of infection, inflammation, and destruction of lung tissue which leads to bronchiectasis. Practice guidelines in North America and the UK differ greatly with regard to the advice given on presc...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,评审

    doi:10.1002/ppul.20305

    authors: Smyth A

    更新日期:2005-12-01 00:00:00

  • A novel combined treatment for plasminogen deficiency with lung involvement.

    abstract::Plasminogen deficiency is characterized by fibrin-rich pseudomembrane formation on all mucosal surfaces, particularly the conjunctiva. Respiratory system involvement is common; fibrin often obstructs the upper or lower respiratory tract, causing death. Although many treatments have been applied, no definitive treatmen...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24563

    authors: Kilinc AA,Tarcin G,Kurugoglu S,Schuster V,Cokugras H,Celkan T

    更新日期:2020-01-01 00:00:00

  • Effect of night symptoms and disease severity on subjective sleep quality in children with non-cystic-fibrosis bronchiectasis.

    abstract:BACKGROUND:Night-time symptoms and hypoxemia during sleep may affect sleep quality in children with chronic lung disease such as bronchiectasis. Poor sleep quality may impair growth, learning, and emotional development of children. Our aim was to assess the sleep quality and associated factors in children with non-cyst...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21454

    authors: Erdem E,Ersu R,Karadag B,Karakoc F,Gokdemir Y,Ay P,Akpinar IN,Dagli E

    更新日期:2011-09-01 00:00:00

  • Horseshoe lung with pseudo-ring-sling complex.

    abstract::We report on a 1-month-old boy who presented with a "horseshoe" lung, complete "O" rings of the trachea, and an unusual course of the left pulmonary artery mimicking a left pulmonary artery sling. Computed tomography, cardiac catheterization, and bronchoscopy were performed to confirm the rare coexistence of these ano...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.10172

    authors: Hwang HK,Chen MR,Chen SJ,Kao HA,Lee KS,Shih SL

    更新日期:2002-11-01 00:00:00

  • Continuous positive airway pressure by nasal prongs in bronchiolitis.

    abstract::Ten infants with evidence of impending respiratory failure from severe bronchiolitis were successfully treated with continuous positive airway pressure (NCPAP) with double nasal prongs. Their mean (SD) age was 6.7 (3.8) months and mean (SD) body weight was 7.1 (2.1) kg. Respiratory assessments were made immediately be...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章

    doi:10.1002/ppul.1950160305

    authors: Soong WJ,Hwang B,Tang RB

    更新日期:1993-09-01 00:00:00

  • Development of the pulmonary airways in the fetal rat and its relation to the prenatal environment.

    abstract::We studied the left lung using multi-focus microphotography in 378 rat fetuses, assessing airway branching from day 13 to day 19 of gestation, and lung growth variables from day 13 to day 21. Longitudinal growth, and monopodial and dichotomous branching brought about a consistent airway pattern with variations within ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1099-0496(199604)21:4<219::AID-PPUL3

    authors: Rotschild A,Massoud EA,Solimano A,Puterman ML,Sekhon HS,Thurlbeck WM

    更新日期:1996-04-01 00:00:00