Prophylactic antibiotics in cystic fibrosis: a conviction without evidence?

abstract：AIM:The aim of this study was to investigate the status and effects of vitamin D supplement as adjuvant therapy in the management of respiratory distress syndrome (RDS) in preterm infants. PATIENT AND METHODS:Vitamin D was prospectively studied in 196 preterm neonates, 96 of them developed RDS, which further subdivide...

journal_title：Pediatric pulmonology

authors： Al-Beltagi M,Rowiesha M,Elmashad A,Elrifaey SM,Elhorany H,Koura HG

更新日期：2020-01-01 00:00:00

abstract：SUMMARY:Ataxia-telangiectasia (A-T) is a rare autosomal recessive disorder caused by mutations in the ATM gene, resulting in faulty repair of breakages in double-stranded DNA. The clinical phenotype is complex and is characterized by neurologic abnormalities, immunodeficiencies, susceptibility to malignancies, recurren...

journal_title：Pediatric pulmonology

authors： McGrath-Morrow SA,Gower WA,Rothblum-Oviatt C,Brody AS,Langston C,Fan LL,Lefton-Greif MA,Crawford TO,Troche M,Sandlund JT,Auwaerter PG,Easley B,Loughlin GM,Carroll JL,Lederman HM

更新日期：2010-09-01 00:00:00

abstract：:A variety of postnatal therapies have been and will be evaluated for prevention or treatment of neonatal chronic lung disease (CLD). A simple method for early selection of the highest risk infants would optimize intervention trials. Our study compared a clinical scoring system for predicting neonatal CLD (defined at 3...

journal_title：Pediatric pulmonology

authors： Yoder BA,Anwar MU,Clark RH

更新日期：1999-06-01 00:00:00

abstract：:Bronchial reactivity was assessed in 66 children with bronchial asthma (aged 8-15 years) by provocation with histamine-HCl during a symptom-free period. A significant bronchial reaction to histamine was defined as a 50% increase in the resistance of the respiratory system (Rrs) determined by the forced oscillation tec...

journal_title：Pediatric pulmonology

authors： Holmgren D,Engström I,Bjure J,Sixt R,Aberg N

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Cystic fibrosis (CF) genotyping has garnered increased attention since the discovery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in 1989 led to the identification of over 1700 mutations on chromosome 7. Yet, little is known about the genetic profile of CF patients in Turkey. This s...

journal_title：Pediatric pulmonology

authors： Atag E,Bas Ikizoglu N,Ergenekon AP,Gokdemir Y,Eralp EE,Ata P,Ersu R,Karakoc F,Karadag B

更新日期：2019-06-01 00:00:00

abstract：:Angiogenesis is an important mechanism of airway remodeling in lung disease. We previously demonstrated that serum vascular endothelial growth factor (VEGF) is elevated in cystic fibrosis (CF) patients and declines with therapy for pulmonary exacerbation. We hypothesized that VEGF is elevated early in the course of CF...

journal_title：Pediatric pulmonology

authors： Watts KD,McColley SA

更新日期：2011-07-01 00:00:00

abstract：:Tracheoesophageal fistula (TEF) with esophageal atresia (EA) is a common congenital anomaly that is associated with significant respiratory morbidity throughout life. The objective of this document is to provide a framework for the diagnosis and management of the respiratory complications that are associated with the ...

journal_title：Pediatric pulmonology

authors： Koumbourlis AC,Belessis Y,Cataletto M,Cutrera R,DeBoer E,Kazachkov M,Laberge S,Popler J,Porcaro F,Kovesi T

更新日期：2020-10-01 00:00:00

abstract：:Childhood interstitial lung disease (chILD) comprises a wide heterogeneous group of rare parenchymal lung disorders associated with substantial morbidity and mortality. Pulmonary hypertension is a common comorbidity in adults with interstitial lung disease (ILD) and associated with poor survival. We aimed to systemati...

journal_title：Pediatric pulmonology

authors： Bromley S,Vizcaya D

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:The present pilot study was performed to evaluate the HPA axis and ANS activity by measuring salivary cortisol and α-amylase diurnal trajectory and production, respectively, in mild or moderate-to-severe (MS) OSA-affected, but otherwise healthy, children. Moreover, a correlative analysis was performed betwee...

journal_title：Pediatric pulmonology

authors： Patacchioli FR,Tabarrini A,Ghiciuc CM,Dima-Cozma LC,Prete A,Bianchini C,Nicoletti F,Gozal D,Villa MP

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the utility of the Cystic Fibrosis Questionnaire-Revised (CFQ-R) with toddlers and preschool-aged children. Clinically relevant relations between health-related quality of life (HRQOL), stress, and mealtime behaviors have not been examined. It was hypothesized that p...

journal_title：Pediatric pulmonology

authors： Driscoll KA,Modi AC,Filigno SS,Brannon EE,Chamberlin LA,Stark LJ,Powers SW

更新日期：2015-06-01 00:00:00

abstract：:This study sought to determine if a clinical pathway developed and executed by specialists in pediatric asthma would reduce hospital costs and length of stay (LOS). The study design was a retrospective, nonrandomized, controlled trial. Subjects were children aged 2-18 years (N = 1,004) with a history of recurrent whee...

journal_title：Pediatric pulmonology

authors： Wazeka A,Valacer DJ,Cooper M,Caplan DW,DiMaio M

更新日期：2001-09-01 00:00:00

abstract：:We retrospectively reviewed the spectrum, course, and outcome of pulmonary diseases in 66 children with AIDS, hospitalized between 1982 and 1988, prior to the use of zidovudine. Fifty-two of the 66 (79%) patients developed pulmonary problems. In fifty-two percent of all patients, a pulmonary problem was the first symp...

journal_title：Pediatric pulmonology

authors： Marolda J,Pace B,Bonforte RJ,Kotin NM,Rabinowitz J,Kattan M

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Children with adenoid hypertrophy (AH) have impaired respiratory system defense mechanisms, such as mucociliary clearance. We hypothesized that AH negatively affects one of the most important aspects of mucociliary clearance-ciliary beat frequency (CBF) and that adenoidectomy could potentially restore this e...

journal_title：Pediatric pulmonology

authors： Marusiakova L,Durdik P,Jesenak M,Bugova G,Kvassayova J,Oppova D,Banovcin P

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:a: To evaluate the long-term outcome of parapneumonic effusions (PPE) in children regarding lung function and exercise tolerance, (b) to investigate the role of bronchial asthma in the outcome of PPE. METHODS:The design of the study included 51 children with PPE, at least 2 years after the initial infection...

journal_title：Pediatric pulmonology

authors： Kontouli K,Hatziagorou E,Kyrvasilis F,Roilides E,Emporiadou M,Tsanakas J

更新日期：2015-06-01 00:00:00

abstract：:To determine the natural history of lung vascular remodeling and cardiac changes in the rat model of persistent pulmonary hypertension syndrome (PPHN) of the newborn, we studied fetal rats subjected to maternal indomethacin administration initiated on day 19 of gestation and continued for 2, 3, or 4 days. Animals rece...

journal_title：Pediatric pulmonology

authors： Fabris VE,Pato MD,Belik J

更新日期：2001-05-01 00:00:00

abstract：:The cotton rat was evaluated as a model for anti-inflammatory and antiviral influenza therapy. Beginning 3 days after intranasal infection with 10(7) tissue culture infectious doses-50% (TCID)(50) of an H3N2 human influenza, animals were treated topically via intranasal lavage with a range of doses of triamcinolone ac...

journal_title：Pediatric pulmonology

authors： Ottolini M,Blanco J,Porter D,Peterson L,Curtis S,Prince G

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To determine the effect of changing electrode positions on vital signs and respiratory effort parameters measured with transcutaneous electromyography of the diaphragm (dEMG) in preterm infants. METHODS:In this observational study, simultaneous dEMG measurements were performed at the standard position and at...

journal_title：Pediatric pulmonology

authors： van Leuteren RW,Bekhuis RE,de Waal CG,de Jongh FH,van Kaam AH,Hutten GJ

更新日期：2020-02-01 00:00:00

abstract：:Lane-Hamilton syndrome refers to the uncommon co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co-existing non-diarrheal CD. Institution of gluten-free diet in each of the three children resulted in amelioration of th...

journal_title：Pediatric pulmonology

authors： Sethi GR,Singhal KK,Puri AS,Mantan M

更新日期：2011-03-01 00:00:00

abstract：:Although airway obstruction and chronic endobronchial infection have long been recognized as major factors in the pathogenesis of lung disease in cystic fibrosis (CF), only recently has it been recognized that the inflammatory process itself may be responsible in a major way for destroying the lungs. The most characte...

journal_title：Pediatric pulmonology

authors： Konstan MW,Berger M

更新日期：1997-08-01 00:00:00

abstract：:Sudden unexplained deaths have been reported in 13% [corrected] of Familial Dysautonomia (FD) subjects. To characterize cardiorespiratory dysregulation in children with FD that might contribute to potential sudden death, respiratory inductance plethysmography (chest/abdomen), ECG, hemoglobin saturation, and pulse wave...

journal_title：Pediatric pulmonology

authors： Weese-Mayer DE,Kenny AS,Bennett HL,Ramirez JM,Leurgans SE

更新日期：2008-03-01 00:00:00

abstract：:We enrolled 30 infants (median age 3 months, range 1-12 months), hospitalized for bronchiolitis in a randomized double-blind trial, to examine the efficacy and safety of nebulized epinephrine compared to salbutamol. Once admitted, patients were treated with either nebulized 0.5 mg of an 0.1% epinephrine solution (0.5 ...

journal_title：Pediatric pulmonology

authors： Bertrand P,Araníbar H,Castro E,Sánchez I

更新日期：2001-04-01 00:00:00

abstract：:During the past five decades there has been increasing interest in the potential anti-inflammatory effects of macrolide antibiotics. Low-dose macrolide therapy has dramatically increased survival in patients with diffuse panbronchiolitis, a disease with many similarities to cystic fibrosis (CF). This has led to furthe...

journal_title：Pediatric pulmonology

authors： Jaffé A,Bush A

更新日期：2001-06-01 00:00:00

abstract：:C-reactive protein (CRP) concentrations were evaluated in 9 cystic fibrosis (CF) patients with acute pulmonary exacerbations and 14 patients with acute exacerbations of asthma without any symptoms of an acute infection. CRP concentrations were serially evaluated over the course of therapy in CF patients and compared w...

journal_title：Pediatric pulmonology

authors： Friesen CA,Wiens LA,Burry VF,Portnoy J,Roberts CC

更新日期：1995-10-01 00:00:00

abstract：:The consequences of poor quality and/or inadequate sleep in children and adolescents have become a major public health concern, and one in which pediatric health care professionals have become increasingly involved. In particular, insufficient and/or fragmented sleep resulting from primary sleep disorders such as obst...

journal_title：Pediatric pulmonology

authors： Owens JA

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:There is currently no evidence-based method for defining competency in pediatric flexible bronchoscopy (FB). Based on expert opinion, guidelines using numbers of procedures have been published in defining competency for pediatric FB. The purpose of this study was to formally survey the opinion of USA pediatri...

journal_title：Pediatric pulmonology

authors： Leong AB,Green CG,Kurland G,Wood RE

更新日期：2014-06-01 00:00:00

abstract：:Forced oscillatory respiratory resistance was measured in 138 healthy children aged 2- to 16-years-old using a commercial unit. Regression analysis was performed using the resistance measurements obtained at frequencies of 6 Hz and 26 Hz and averages of measurements obtained at frequencies of from 6-26 Hz, 6-10 Hz, an...

journal_title：Pediatric pulmonology

authors： Hordvik NL,König P,Morris DA,Kreutz C,Pimmel RL

更新日期：1985-05-01 00:00:00

abstract：:The jet nebulizer is a common device used for administering aerosol medication in young children. However, compared to a metered dose inhaler-spacer (MDI-spacer), it takes more time and personnel. This study aimed to compare the efficacy of salbutamol aerosol therapy given via these two devices in young wheezing child...

journal_title：Pediatric pulmonology

authors： Deerojanawong J,Manuyakorn W,Prapphal N,Harnruthakorn C,Sritippayawan S,Samransamruajkit R

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Severe inflammation plays a vital role in the pathogenesis of meconium aspiration syndrome (MAS). Intratracheal (IT) instillation of corticosteroids may be beneficial for MAS in optimizing local effect and reducing systemic adverse effects, but the optimum dosing course remains open to question. METHODS:Thi...

journal_title：Pediatric pulmonology

authors： Lin CH,Jeng MJ,Yang YC,Hsiao YH,Kou YR

更新日期：2017-07-01 00:00:00

abstract：AIM:Children with respiratory conditions benefit from care provided by pediatric pulmonologists. As these physicians are a small portion of the overall pediatric workforce, it is necessary to understand the practices and career plans of these specialists. METHODS:An internet survey was developed by the American Academ...

journal_title：Pediatric pulmonology

authors： Harris C,Katkin J,Cataletto M,Dorkin H,Laskosz L,Ruch-Ross H

更新日期：2019-04-01 00:00:00

abstract：:We recently reported that prenatal glucocorticoid therapy is less effective at promoting an improvement in lung function in male than in female sheep. This observation, and the higher incidence of respiratory distress syndrome in human males, suggests that the male fetal lung may be less responsive to glucocorticoids ...

journal_title：Pediatric pulmonology

authors： Kovar J,Waddell BJ,Sly PD,Willet KE

更新日期：2001-07-01 00:00:00