Chronic headache: New advances in treatment strategies.

abstract：BACKGROUND:Tricyclic antidepressants (TCA) are often used in the treatment of painful polyneuropathy. Venlafaxine is a serotonin and weak noradrenaline reuptake inhibitor antidepressant with a different profile of other pharmacologic actions from those of TCA. OBJECTIVE:To test if venlafaxine would relieve painful pol...

journal_title：Neurology

authors： Sindrup SH,Bach FW,Madsen C,Gram LF,Jensen TS

更新日期：2003-04-22 00:00:00

abstract：OBJECTIVE:To examine the genetic relationships among epilepsies with different seizure types--myoclonic, absence, and generalized tonic-clonic--within the idiopathic generalized epilepsies (IGEs). BACKGROUND:Careful phenotype definition in the epilepsies may allow division into groups that share susceptibility genes. ...

journal_title：Neurology

authors： Winawer MR,Marini C,Grinton BE,Rabinowitz D,Berkovic SF,Scheffer IE,Ottman R

更新日期：2005-08-23 00:00:00

abstract：OBJECTIVES:This study examines the anatomical correlates of naming vs recognizing faces using a novel measure that utilizes culturally relevant and age-appropriate items, the Northwestern University Famous Faces (NUFFACE) Test, in primary progressive aphasia (PPA), a syndrome characterized by progressive language defic...

journal_title：Neurology

authors： Gefen T,Wieneke C,Martersteck A,Whitney K,Weintraub S,Mesulam MM,Rogalski E

更新日期：2013-08-13 00:00:00

abstract：:We studied a family with an extrapyramidal disorder characterized by childhood onset of lower-limb and axial dystonia, followed by parkinsonism. Dramatic response to levodopa therapy and minimal progression in adult life was seen. The family included five generations of affected members of both sexes in an autosomal d...

journal_title：Neurology

authors： Nygaard TG,Duvoisin RC

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:We determined whether Gram-negative bacterial molecules are associated with Alzheimer disease (AD) neuropathology given that previous studies demonstrate Gram-negative Escherichia coli bacteria can form extracellular amyloid and Gram-negative bacteria have been reported as the predominant bacteria found in no...

journal_title：Neurology

authors： Zhan X,Stamova B,Jin LW,DeCarli C,Phinney B,Sharp FR

更新日期：2016-11-29 00:00:00

abstract：OBJECTIVE:Myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) associated disorder (MOGAD) often manifests with recurrent CNS demyelinating attacks. The optimal treatment for reducing relapses is unknown. To help determine the efficacy of long-term immunotherapy in preventing relapse in patients with MOGAD, w...

journal_title：Neurology

authors： Chen JJ,Flanagan EP,Bhatti MT,Jitprapaikulsan J,Dubey D,Lopez Chiriboga ASS,Fryer JP,Weinshenker BG,McKeon A,Tillema JM,Lennon VA,Lucchinetti CF,Kunchok A,McClelland CM,Lee MS,Bennett JL,Pelak VS,Van Stavern G,Adesina

更新日期：2020-07-14 00:00:00

abstract：OBJECTIVE:To define the natural history of the C9orf72 amyotrophic lateral sclerosis (C9ALS) patient population, develop disease biomarkers, and characterize patient pathologies. METHODS:We prospectively collected clinical and demographic data from 116 symptomatic C9ALS and 12 non-amyotrophic lateral sclerosis (ALS) f...

journal_title：Neurology

authors： Cammack AJ,Atassi N,Hyman T,van den Berg LH,Harms M,Baloh RH,Brown RH,van Es MA,Veldink JH,de Vries BS,Rothstein JD,Drain C,Jockel-Balsarotti J,Malcolm A,Boodram S,Salter A,Wightman N,Yu H,Sherman AV,Esparza TJ,Mc

更新日期：2019-10-22 00:00:00

abstract：:The authors conducted a randomized, double-blind, placebo-controlled, twofold crossover study in 16 patients with MS who presented with severe spasticity to investigate safety, tolerability, and efficacy of oral Delta(9)-Tetrahydrocannabinol (THC) and Cannabis sativa plant extract. Both drugs were safe, but adverse ev...

journal_title：Neurology

authors： Killestein J,Hoogervorst EL,Reif M,Kalkers NF,Van Loenen AC,Staats PG,Gorter RW,Uitdehaag BM,Polman CH

更新日期：2002-05-14 00:00:00

abstract：:We analyzed our experience with cough, exertional, and vascular sexual headaches, evaluated the interrelationships among them, and examined the possible symptomatic cases. Seventy-two patients consulted us because of headaches precipitated by coughing (n = 30), physical exercise (n = 28), or sexual excitement (n = 14)...

journal_title：Neurology

authors： Pascual J,Iglesias F,Oterino A,Vázquez-Barquero A,Berciano J

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:To survey brain death criteria throughout the world. BACKGROUND:The clinical diagnosis of brain death allows organ donation or withdrawal of support. Declaration of brain death follows a certain set of examinations. The code of practice throughout the world has not been systematically investigated. METHODS:...

journal_title：Neurology

authors： Wijdicks EF

更新日期：2002-01-08 00:00:00

abstract：:The behavioral and anatomic correlates of pure alexia were analyzed in 16 patients. Right homonymous hemianopia failed to appear in three patients, who had right achromatopsia instead. Color anomia and unilateral optic ataxia were seen in six patients. Memory defects were found in two patients. Visual agnosia was note...

journal_title：Neurology

authors： Damasio AR,Damasio H

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Few population-based studies with long-term follow-up have compared risk of recurrent stroke and cardiac events after first ischemic stroke. The relative risk of these two outcomes may inform treatment decisions. METHODS:In the population-based Northern Manhattan Study, first ischemic stroke patients age 40...

journal_title：Neurology

authors： Dhamoon MS,Sciacca RR,Rundek T,Sacco RL,Elkind MS

更新日期：2006-03-14 00:00:00

abstract：:MRI and CSF investigations revealed meningeal involvement in a 29-year-old patient with biopsy-confirmed Wegener's granulomatosis. The intracranial manifestation of Wegener's granulomatosis was supported by the detection of pathologic circulating antineutrophil cytoplasm (c-ANCA) in the CSF. We monitored disease activ...

journal_title：Neurology

authors： Spranger M,Schwab S,Meinck HM,Tischendorf M,Sis J,Breitbart A,Andrassy K

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the effect of intensive care unit continuous EEG (cEEG) monitoring on inpatient mortality, hospital charges, and length of stay. METHODS:A retrospective cross-sectional study was conducted using the Nationwide Inpatient Sample, a dataset representing 20% of inpatient discharges in nonfederal US ...

journal_title：Neurology

authors： Ney JP,van der Goes DN,Nuwer MR,Nelson L,Eccher MA

更新日期：2013-12-03 00:00:00

abstract：BACKGROUND:Only a small percentage of patients with acute stroke are treated with recombinant tissue plasminogen activator (rt-PA). OBJECTIVE:To investigate why patients with right-hemisphere strokes seem at high risk of not receiving rt-PA. METHODS:This study includes two phases. Phase 1: the authors compared demogr...

journal_title：Neurology

authors： Di Legge S,Fang J,Saposnik G,Hachinski V

更新日期：2005-07-12 00:00:00

abstract：:Cognitive impairment is a frequent manifestation of advanced human immunodeficiency virus (HIV) infection. The response to antiretroviral medication is often partial and poorly sustained. Recent studies suggest that free radical production within the CNS and neuronal apoptosis may play important roles in the pathogene...

journal_title：Neurology

authors：

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:The gradual development of cutaneous allodynia during the course of a migraine attack is commonly detected by quantitative sensory testing (QST) in migraineurs seeking secondary and tertiary medical help. In this study, the authors developed a questionnaire that tested the recollection of the patients on thei...

journal_title：Neurology

authors： Jakubowski M,Silberstein S,Ashkenazi A,Burstein R

更新日期：2005-11-08 00:00:00

abstract：:We tested three serotonin antagonists--lysergic acid diethylamide (LSD), 2-bromolysergic acid diethylamide (BOL), and cinanserin--for effects on experimental spinal cord ischemia in the rabbit. Blood flow to spinal cord was obstructed. Drugs were administered before or after initiation of occlusion, and flow was later...

journal_title：Neurology

authors： Zivin JA,Venditto JA

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVE:To address the role of cell death regulatory genes of the bcl-2 and caspase families in the neuropathology of human epilepsy using tissue extracted from patients undergoing temporal lobectomy for intractable seizures. METHODS:Using Western blotting and immunohistochemistry, the authors investigated the expre...

journal_title：Neurology

authors： Henshall DC,Clark RS,Adelson PD,Chen M,Watkins SC,Simon RP

更新日期：2000-07-25 00:00:00

abstract：:Although motor fibers in the sural nerve were already described in three individuals, this nerve is considered purely sensory. We investigated the occurrence of motor fibers in 331 sural nerves of 207 individuals. We found motor fibers in 15 nerves (4.5%) or in 13 individuals (6.2%). The identification of motor fibers...

journal_title：Neurology

authors： Amoiridis G,Schöls L,Ameridis N,Przuntek H

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To study the safety of off-label IV thrombolysis in patients with very severe stroke (NIH Stroke Scale [NIHSS] scores >25) compared with severe stroke (NIHSS scores 15-25), where treatment is within European regulations. METHODS:Data were analyzed from 57,247 patients with acute ischemic stroke receiving IV ...

journal_title：Neurology

authors： Mazya MV,Lees KR,Collas D,Rand VM,Mikulik R,Toni D,Wahlgren N,Ahmed N

更新日期：2015-12-15 00:00:00

abstract：:The authors examined the neural function of a postmeningitic deaf-blind patient who regained his hearing with a multichannel cochlear implant. Auditory stimuli activated the temporal cortices of both sides in a manner similar to that of controls, reflecting the successful recruitment of the auditory cortex after impla...

journal_title：Neurology

authors： Osaki Y,Takasawa M,Doi K,Nishimura H,Iwaki T,Imaizumi M,Oku N,Hatazawa J,Kubo T

更新日期：2006-09-12 00:00:00

abstract：:The authors describe two novel mutations of the acid alpha-glucosidase gene, P361L and R437C, which define the juvenile-onset glycogen storage disease type II (GSDII) in a 16-year-old Chinese patient. The asymptomatic 13-year-old brother of the proband is also a compound heterozygote of the two mutations. These result...

journal_title：Neurology

authors： Lam CW,Yuen YP,Chan KY,Tong SF,Lai CK,Chow TC,Lee KC,Chan YW,Martiniuk F

更新日期：2003-02-25 00:00:00

abstract：OBJECTIVES:To test the hypothesis that neuropsychiatric symptomatology is predictive of the success of seizure control in patients newly treated with antiepileptic drugs (AEDs), and that this predictive value adds to that provided by other clinical, imaging, and genomic factors in a multivariate model. METHODS:One hun...

journal_title：Neurology

authors： Petrovski S,Szoeke CE,Jones NC,Salzberg MR,Sheffield LJ,Huggins RM,O'Brien TJ

更新日期：2010-09-14 00:00:00

abstract：:A 51-year-old man had a 4-month history of progressive headache and gradual onset of somnolence. MRI suggested spontaneous intracranial hypotension (SIH) with diencephalic compression, but he did not improve after three epidural blood patches. He became alert following intrathecal saline infusion that normalized his C...

journal_title：Neurology

authors： Pleasure SJ,Abosch A,Friedman J,Ko NU,Barbaro N,Dillon W,Fishman RA,Poncelet AN

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:We aimed to perform an observational study of age at loss of independent ambulation (LoA) and side-effect profiles associated with different glucocorticoid corticosteroid (GC) regimens in Duchenne muscular dystrophy (DMD). METHODS:We studied 340 participants in the Cooperative International Neuromuscular Res...

journal_title：Neurology

authors： Bello L,Gordish-Dressman H,Morgenroth LP,Henricson EK,Duong T,Hoffman EP,Cnaan A,McDonald CM,CINRG Investigators.

更新日期：2015-09-22 00:00:00

abstract：:Thirty-one individuals awaiting trial or sentencing for murder or undergoing an appeal process requested a neurologic examination through legal counsel. We attempted in each instance to obtain EEG, MRI or CT, and neuropsychological testing. Neurologic examination revealed evidence of "frontal" dysfunction in 20 (64.5%...

journal_title：Neurology

authors： Blake PY,Pincus JH,Buckner C

更新日期：1995-09-01 00:00:00

abstract：:Arm-diaphragm synkinesis may occur after injury to the proximal portion of the brachial plexus or cervical nerve roots. Regenerating axons of phrenic motor neurons are misdirected to supply limb muscles. Electrodiagnostic investigations of three patients with symptoms referable to upper brachial plexus or cervical roo...

journal_title：Neurology

authors： Swift TR,Leshner RT,Gross JA

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:There is no generally accepted instrument for measuring quality of life (QOL) in patients with ALS. Current instruments are either too heavily weighted toward strength and physical function or useful for the evaluation of individuals but of less utility in assessing large samples. OBJECTIVE:To develop and e...

journal_title：Neurology

authors： Simmons Z,Felgoise SH,Bremer BA,Walsh SM,Hufford DJ,Bromberg MB,David W,Forshew DA,Heiman-Patterson TD,Lai EC,McCluskey L

更新日期：2006-11-14 00:00:00

abstract：:In this double-blind, placebo-controlled trial, we investigated the effect of the catechol-O-methyltransferase inhibitor tolcapone 100 or 200 mg three times daily on activities of daily living and motor function in 298 patients with parkinsonism receiving levodopa but without motor fluctuations. At 6 months, both dosa...

journal_title：Neurology

authors： Waters CH,Kurth M,Bailey P,Shulman LM,LeWitt P,Dorflinger E,Deptula D,Pedder S

更新日期：1997-09-01 00:00:00