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Cardiomyopathy: a role for nitric oxide?

Abstract：

:The negative inotropism, myocardial dilatation and cytotoxicity in inflammatory heart disorders may be due to increased generation of nitric oxide (NO) by immunological induction of a high output NO pathway. This short review discusses the initial experiments which lead to this hypothesis, and evaluates data that this pathway exists in animal and human cardiomyopathic disorders. It is proposed that manipulation of this pathway may prove to be beneficial in patients with these disorders.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

de Belder A,Moncada S

doi

10.1016/0167-5273(95)02386-b

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

263-8

issue

3

eissn

0167-5273

issn

1874-1754

pii

016752739502386B

journal_volume

50

pub_type

杂志文章,评审

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