Abstract：
OBJECTIVE:To analyze whether left ventricular dyssynchrony (LVD) at baseline is predictive for long-term outcome in heart failure (CHF) patients with left ventricular (LV) dysfunction and conduction disturbances treated with cardiac resynchronization therapy (CRT). METHODS:In 535 consecutive individuals with CHF scheduled for implantation of a CRT device, LVD was assessed by tissue Doppler imaging (TDI), defined as an electromechanical delay (EMD) difference of ≥40 ms in 2 opposed left ventricular wall regions (septal vs. lateral, anterior vs. inferior). All-cause mortality, heart transplantation, or assist device implantation was defined as combined primary end point. Secondary end points were measures of reverse LV remodeling and of symptomatic improvement. RESULTS:Mean follow-up was 68 ± 36 [range: 4-150] months. LVD at baseline was present in 308 patients (61%). Of these, 24% reached the combined primary endpoint in contrast to 58% of patients without LVD (p < 0.001). Furthermore, patients with LVD showed pronounced improvement of all secondary end point parameters. In our cohort LVD was an independent predictor for outcome (hazard ratio [95% CI]: 0.30 [0.21-0.42], p < 0.001). CONCLUSIONS:LVD at baseline as assessed by TDI is associated with a more pronounced clinical improvement and is a predictor for transplant-free long-term survival in CRT recipients.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Prinz C,Felice CD,Lehmann R,Schwarz M,Prinz EM,Bitter T,Vogt J,Lamp B,Faber L,Horstkotte Ddoi
10.1016/j.ijcard.2013.06.060subject
Has Abstractpub_date
2013-10-09 00:00:00pages
3932-9issue
4eissn
0167-5273issn
1874-1754pii
S0167-5273(13)01114-5journal_volume
168pub_type
杂志文章abstract：:Patent ductus arteriosus (PDA) can occur as part of more congenital cardiac malformations or as an isolate finding. Spontaneous, transcatheter, surgical closure, and pharmacological treatment have been reported. We present a case of recurrent PDA after the initial course of a pharmacological treatment. Also this case ...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2009.02.017
更新日期：2011-05-05 00:00:00
abstract：:Blood flow velocities were recorded using Doppler ultrasound in 40 babies aged between 1 day and 4 weeks who had coarctation of the aorta or interruption of the aortic arch. High velocity jets of 3 m/sec or more in the descending aorta were detected in only 3 patients, two of whom had interruption of the aortic arch. ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(89)90333-1
更新日期：1989-04-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2005.03.028
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2019.12.051
更新日期：2020-05-15 00:00:00
abstract：BACKGROUND:Recently, stent fracture (SF) of sirolimus-eluting stents (SES) has been shown to be associated with an increased risk of in-stent restenosis. We sought to evaluate the incidence, predictors and clinical outcome of SF after SES implantation in comparable unselected lesions. METHODS:A total of 430 lesions of...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2007.12.067
更新日期：2009-04-17 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.04.131
更新日期：2016-08-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.03.136
更新日期：2018-07-15 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(99)00053-4
更新日期：1999-07-01 00:00:00
abstract：:The diagnosis of cardiac syndrome X (CSX) is often a diagnosis of exclusion and hence requires a systematic and comprehensive assessment of each patient to rule out more common causes of chest discomfort. The definitive technique for the diagnosis of CSX is not currently available. Many patients with chest pain and no...
journal_title：International journal of cardiology
pub_type： 评论,信件
doi：10.1016/j.ijcard.2008.11.110
更新日期：2010-07-09 00:00:00
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journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.11.056
更新日期：2008-11-12 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(01)00626-x
更新日期：2002-03-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
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更新日期：2017-01-15 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2016.02.122
更新日期：2016-03-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
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更新日期：2013-10-09 00:00:00
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journal_title：International journal of cardiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0167-5273(02)00250-4
更新日期：2003-02-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2012.05.044
更新日期：2012-11-29 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(90)90102-b
更新日期：1990-03-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(94)02263-i
更新日期：1995-03-24 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2015.12.015
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journal_title：International journal of cardiology
pub_type： 信件
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journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2006.04.009
更新日期：2006-11-10 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2015.03.065
更新日期：2015-04-15 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(85)90261-x
更新日期：1985-05-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.07.170
更新日期：2016-11-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2008.04.047
更新日期：2009-07-10 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2011.08.059
更新日期：2012-09-20 00:00:00
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journal_title：International journal of cardiology
pub_type： 评论,历史文章,信件
doi：10.1016/j.ijcard.2008.04.053
更新日期：2009-08-14 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2014.03.156
更新日期：2014-06-01 00:00:00
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journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.10.051
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:The involvement of iron in anthracycline cardiotoxicity is supported by extensive experimental data, and by the preventive efficacy of dexrazoxane, an iron chelator. However, no clinical evidence of anthracycline-induced cardiac iron accumulation is available and the influence of previous iron overload or of...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2010.09.046
更新日期：2012-02-09 00:00:00
