Abstract：
:Increased lipid oxidative stress has been recently implicated in the pathogenesis of coronary artery spasm. Small, dense LDL with high susceptibility to oxidation may be linked to the genesis of coronary vasospasm. The relative migratory distance of the predominant densitometric peak of LDL from that of VLDL to that of HDL in a 3% polyacrylamide gel electrophoresis was determined as a measure of LDL particle size in 49 patients with coronary spastic angina (CSA), in 56 patients with stable effort angina and a significant coronary artery stenosis (SEA) and also in 40 control subjects without coronary artery disease (Control). The incidence of detection of small, dense LDL (particle diameter <25.5 nm) or a relative migratory distance above 0.36 was significantly higher in CSA (57%) and also in SEA (39%) than in Control (20%). In SEA, a significantly higher serum level of triglyceride was noted in the subgroup with the small, dense LDL as compared with the subgroup without. In contrast, in CSA, the serum level of triglyceride was not significantly different between the subgroups with and without the small, dense LDL, although significantly lower serum levels of both HDL-cholesterol and alpha-tocopherol were noted in the former. In 16 patients of CSA, the detection of the small, dense LDL was significantly decreased after a >6-month angina-free period (69-->31%). We conclude that patients with coronary spastic angina had smaller LDL particles, associated not with hypertriglyceridemia but low serum levels of both HDL-cholesterol and vitamin E. Dyslipidemia with small, dense LDL may be related to the genesis of coronary vasospasm.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Miwa Kdoi
10.1016/s0167-5273(02)00250-4subject
Has Abstractpub_date
2003-02-01 00:00:00pages
193-201issue
2-3eissn
0167-5273issn
1874-1754pii
S0167527302002504journal_volume
87pub_type
临床试验,杂志文章abstract：BACKGROUND:Aortic stenosis (AS) poses a perioperative management dilemma to physicians looking after patients who require non-cardiac surgery. The objective of this review is to investigate mortality and adverse cardiovascular events in patients with and without AS who underwent non-cardiac surgery. METHODS:We searche...
journal_title：International journal of cardiology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ijcard.2017.04.037
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Several intervention studies have investigated the relation between potassium intake and blood-pressure, particularly in hypertensive subjects. However, uncertainties still exist about the existence and the amount of such an effect, and about the role of some potential effect-modifiers, including the baselin...
journal_title：International journal of cardiology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ijcard.2016.12.048
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Intravascular ultrasound (IVUS) has been used for assessment of the coronary arteries. However, few IVUS studies have been reported on the aorta. MATERIALS AND METHODS:To assess the presence of atherosclerotic disease in the aorta by the use of IVUS, 29 patients with heart disease (24 men and 5 women; mean ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2006.12.012
更新日期：2008-01-24 00:00:00
abstract：:In conclusion, the data shows that in excellent quality studies such as those obtained in vitro, 3D echocardiography is as accurate in describing the volume of the left ventricle as is angiography. When excellent quality images are obtained, the endocardial wall motion, wall thickening and thinning are better describe...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(85)90180-9
更新日期：1985-01-01 00:00:00
abstract：:This report presents a 60-year-old female who had acute anteroseptal myocardial infarction and a grade 3/6 pansystolic murmur at left lower sternal border. Color Doppler echocardiographic examination revealed the presence of a ventricular septal defect which was later confirmed by contrast left ventriculography and at...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(91)90276-u
更新日期：1991-04-01 00:00:00
abstract：PURPOSE:In chronic obstructive pulmonary disease (COPD), cardiovascular system is involved but less is known about role of specific cardiac biomarkers. We aimed to investigate associations between N-terminal pro B-type natriuretic peptide (NT-proBNP) and troponin T during hospitalisation with 6-month outcome. METHODS:...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2012.05.044
更新日期：2012-11-29 00:00:00
abstract：BACKGROUND:There is considerable research interest about the platelet GPIIb/IIIa receptor polymorphisms in CAD. METHODS:We investigated differences in the frequency of the polymorphism in the GPIIb subunit of the receptor HPA-3 (a and b allele) between patients with more extensive coronary thrombosis such as patients ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2007.04.039
更新日期：2008-06-23 00:00:00
abstract：BACKGROUND:The role of programmed ventricular stimulation (PVS) in patients with idiopathic dilated cardiomyopathy (DCM) and syncope receiving implantable cardioverter-defibrillators (ICD) remains controversial. METHODS AND RESULTS:Between 1994 and July 2002, 20 patients with DCM and syncope underwent PVS and ICD impl...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究,评审
doi：10.1016/j.ijcard.2003.12.012
更新日期：2005-02-28 00:00:00
abstract：PURPOSE:The purpose of this study is to explore the periodical patterns of events and deaths related to cardiovascular disease (CVD), acute myocardial infarction (AMI) and stroke in Swiss adults (≥ 18 years). METHODS:Mortality data for period 1969-2007 (N=869,863 CVD events) and hospitalization data for period 1997-20...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2013.01.224
更新日期：2013-10-03 00:00:00
abstract：:The hearts of human embryos, ranging from 3.6 to 25 mM crown-rump length, have been studied in view of the problem of the possible contribution of the atrioventricular endocardial cushions to septation. Serial sections and graphic reconstructions were used. It is concluded that the cushions do not materially contribut...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(85)90261-x
更新日期：1985-05-01 00:00:00
abstract：BACKGROUND:Individuals who experience paroxysmal atrial fibrillation (PAF) are at risk of serious sequelae, including stroke. PAF episodes usually occur in out-of-hospital settings, and patients seek emergency services for differential diagnosis and treatment. METHODS:Medical records of all subscribers to a telemedica...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2010.12.014
更新日期：2012-05-17 00:00:00
abstract：:The recent death of a popular politician in India was followed by a spate of sudden deaths. In this letter, we analyze the deaths as reported in newspapers, and try to arrive at a reason for this strange phenomenon. ...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2009.09.475
更新日期：2010-11-19 00:00:00
abstract：:There is controversy about the influence of QT dispersion on the incidence of early ventricular arrhythmias in patients with acute myocardial infarction (AMI). The QT and QTc dispersion (QTd, QTcd) between two groups of patients with AMI were compared: 39 patients with early sustained ventricular tachycardia or ventri...
journal_title：International journal of cardiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0167-5273(97)00226-x
更新日期：1997-12-19 00:00:00
abstract：:This study examined the risk of cellular phone ringing interference with implantable loop recorders (ILR). The technical manual of ILR warns of potential interference by cellular phone in close proximity to the implanted device, corrupting the data stored in memory or causing inappropriate device operation. The ringin...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2006.04.044
更新日期：2007-03-02 00:00:00
abstract：BACKGROUND/INTRODUCTION:Outcome after ST segment elevation myocardial infarction (STEMI), has improved but patients with high Killip class still have a poor prognosis, and those ≥II need a closer monitoring in a specialized cardiac care unit. PURPOSE:We aimed to determine the predictors of Killip class in a group of p...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2017.07.038
更新日期：2017-12-01 00:00:00
abstract：:We compared the basal coronary artery tone and the constrictive responses to acetylcholine (Ach) and ergonovine (Erg) among three groups of patients: 31 patients (group 1) with variant angina in whom spasm was provoked by low doses of acetylcholine (intracoronary 20 micrograms) or ergonovine (intravenous 50 micrograms...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：
更新日期：1996-07-26 00:00:00
abstract：BACKGROUND:Patent foramen ovale (PFO) closure after a cryptogenic cerebral ischemic event is a routinely procedure. The most used device is Amplatzer™ PFO Occluder 25 mm, but PFOs with complex anatomy require larger device for closure. We compared Amplatzer™ Septal Occluder (ASO) device versus Amplatzer™ PFO Occluder 3...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.10.053
更新日期：2019-03-15 00:00:00
abstract：:The aim of this study was to evaluate differences in the electrophysiological features of atrioventricular reentrant tachycardia (AVRT) in patients with Wolf-Parkinson-White syndrome (WPW) associated with or without atrial fibrillation (AF). We included 119 patients with WPW and orthodromic AVRT during electrophysiolo...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2008.11.114
更新日期：2010-07-09 00:00:00
abstract：:Over a period of 12 years, two cases of pulmonary arterial aneurysms were encountered in our autopsy data of 13 cases of congenital heart defects with right-sided infective endocarditis. Pulmonary arterial aneurysms are rare lesions and may be categorized as central or peripheral. Although early reports implicated tub...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(92)90247-z
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:The activation of NOD-like receptor (NLR) family, pyrin-domain containing 3 (NLRP3) inflammasome has now been proven to have a close connection with myocardial ischemia (MI) during acute phase, but the mechanisms are not completely clear. This study investigated the role of NLRP3 inflammasome in pathogenesis...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2015.05.152
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Several studies have indicated that treatment with angiotensin converting enzyme (ACE) inhibitors and angiotensin II type 1 receptor blockers (ARBs) may reduce the incidence of atrial fibrillation (AF) in hypertensive patients and patients with left ventricular dysfunction. However, there is limited data on ...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2006.08.086
更新日期：2007-08-09 00:00:00
abstract：:Isolated subvalvular pulmonary stenosis (ISPS) is a rare condition, and it is often accompanied by hypertrophic cardiomyopathy. However, diagnosis of ISPS is obscure because of difficulty in comprehension of three-dimensional cardiac anatomy. Whole-heart magnetic resonance imaging (MRI) is a new, totally non-invasive ...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.05.106
更新日期：2009-01-09 00:00:00
abstract：UNLABELLED:Increased QT dispersion, defined as the difference between the maximum and minimum QT interval on the standard 12-lead electrocardiogram is assumed to reflect regional inhomogeneity of ventricular repolarization and has been shown to be associated with an increased risk of arrhythmic events. The purpose of t...
journal_title：International journal of cardiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0167-5273(97)00073-9
更新日期：1997-08-08 00:00:00
abstract：:The aim of our study was to assess the independent relationships of urinary albumin excretion rate (AER), of creatinine clearance (CrCl) and of their interaction with aortic stiffness in hypertensive patients without overt renal insufficiency. We studied 222 untreated nondiabetic essential hypertensives. In patients w...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2010.02.047
更新日期：2010-11-19 00:00:00
abstract：:The optimal degree of revascularization for patients with chronic multivessel coronary artery disease remains an unsolved issue. Intuitively, complete revascularization decreases cardiovascular events and improves outcomes compared to incomplete procedures, but in recent years the concept of incomplete revascularizati...
journal_title：International journal of cardiology
pub_type： 社论
doi：10.1016/j.ijcard.2016.09.055
更新日期：2016-12-01 00:00:00
abstract：:Cardiac sequelae of stab chest wounds may be various and dramatic, and the right ventricle is the most commonly injured chamber. Correct diagnosis of cardiac damage may be done up to many years after the trauma. We describe a rare case of isolated, unexpected flail tricuspid valve detected by transthoracic echocardiog...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/s0167-5273(98)00142-9
更新日期：1998-09-01 00:00:00
abstract：:Abnormalities of diastolic function are common to virtually all forms of cardiac failure. However, the molecular events leading to diastolic dysfunction have not been fully elucidated. We performed a differential proteomic profiling study on diastolic dysfunction hearts induced by renovascular hypertension. Left ventr...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2007.07.003
更新日期：2008-07-04 00:00:00
abstract：BACKGROUND:Experimental studies demonstrate that higher intake of omega-3 fatty acids (n-3 FA) improves insulin sensitivity, however, we reported that n-3 FA 2g therapy, most commonly used dosage did not significantly improve insulin sensitivity despite reducing triglycerides by 21% in patients. Therefore, we investiga...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2014.07.075
更新日期：2014-10-20 00:00:00
abstract：BACKGROUND:Mechanical dyssynchrony (MD) is associated with poor outcomes in many different populations. However, the predictors for the development of MD after chronic right ventricular (RV) pacing are not well known. METHODS:Pacing QRS morphology and MD using echocardiography was analyzed in 175 consecutive patients ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2014.08.131
更新日期：2014-10-20 00:00:00
abstract：BACKGROUND:Myoglobin, cardiac troponin-T and creatine phosphokinase are biochemical indicators of acute coronary syndromes, however, the clinical significance in myocardial ischemia is not well established. Our aim was to elucidate their release kinetics in a well-defined short-lasting myocardial ischemia. METHODS:A c...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2003.12.010
更新日期：2005-02-15 00:00:00
