Is it time to change how we think about incomplete coronary revascularization?

Abstract:

:The optimal degree of revascularization for patients with chronic multivessel coronary artery disease remains an unsolved issue. Intuitively, complete revascularization decreases cardiovascular events and improves outcomes compared to incomplete procedures, but in recent years the concept of incomplete revascularization moved from a sub-optimal or a defective treatment towards the most appropriate revascularization technique in some categories of patients. A reasonable level of incomplete anatomic revascularization has been shown to be safe and achievable with both percutaneous (PCI) and surgical procedures (CABG), despite with different long-term outcomes. What are the mechanisms underlying the clinical benefits of an incomplete revascularization and what are the factors explaining the discrepancy in the long-term clinical outcomes between the two modes of revascularization PCI and CABG? The biological consequences of coronary reperfusion might provide valuable hints in this context and at the same time cast new light on the way we think about incomplete revascularization.

journal_name

Int J Cardiol

authors

Spadaccio C,Nappi F,Nenna A,Beattie G,Chello M,Sutherland FW

doi

10.1016/j.ijcard.2016.09.055

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

295-298

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(16)32311-7

journal_volume

224

pub_type

社论
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