Possible pathogenetic role of Helicobacter pylori infection in cardiac syndrome X.


:The diagnosis of cardiac syndrome X (CSX) is often a diagnosis of exclusion and hence requires a systematic and comprehensive assessment of each patient to rule out more common causes of chest discomfort. The definitive technique for the diagnosis of CSX is not currently available. Many patients with chest pain and normal coronary angiograms have neither metabolic nor hemodynamic evidence of myocardial ischemia. Causes of nonischemic chest pain such as esophageal dysfunction, pulmonary hypertension, and mitral valve prolapse, should also be considered and pursued. Although chronic inflammation induced by Helicobacter pylori infection might play a part in the pathophysiology of CSX, one can conclude that nonischemic chest pain resulting from gastrointestinal disease such as esophagitis, gastritis cannot be completely excluded in the patients with CSX. We believe future large scale prospective cohort studies will be needed to solve that dilemma.


Int J Cardiol


Celik T,Iyisoy A,Yuksel UC




Has Abstract


2010-07-09 00:00:00














  • Reduction and activation of circulating dendritic cells in patients with decompensated heart failure.

    abstract:BACKGROUND:Dendritic cells (DCs) are the most potent antigen-presenting cells and play a central role in initiating the primary immune response. Although increasing evidence supports immune-mediated inflammation plays an important role in the pathophysiology of heart failure, little is known regarding the source and me...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Sugi Y,Yasukawa H,Kai H,Fukui D,Futamata N,Mawatari K,Oba T,Nagata N,Kyougoku S,Koga M,Imaizumi T

    更新日期:2011-03-03 00:00:00

  • In vitro evaluation of vascular endothelial growth factor (VEGF)-eluting stents.

    abstract:BACKGROUND:Vascular endothelial growth factor (VEGF) is a specific endothelial cell mitogen. It promotes re-endothelialisation of the damaged vessel surface seen after stenting. Stent thrombosis and in-stent restenosis are partly related to endothelial denudation caused by stent implantation. We propose using hydrocarb...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Swanson N,Hogrefe K,Javed Q,Gershlick AH

    更新日期:2003-12-01 00:00:00

  • Clinical utility of circulating interleukin-6 concentrations in the detection of functionally relevant coronary artery disease.

    abstract:BACKGROUND:Inflammation plays a major role in the pathogenesis of coronary artery disease (CAD). METHODS:We hypothesized, that quantifying inflammation by measuring circulating interleukin-6 concentrations help in the diagnosis and/or prediction of functionally relevant CAD. Among consecutive patients with symptoms su...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Walter J,Tanglay Y,du Fay de Lavallaz J,Strebel I,Boeddinghaus J,Twerenbold R,Doerflinger S,Puelacher C,Nestelberger T,Wussler D,Amrein M,Badertscher P,Todd J,Rentsch K,Fahrni G,Jeger R,Kaiser C,Reichlin T,Mueller C

    更新日期:2019-01-15 00:00:00

  • Ablation of SIRT3 causes coronary microvascular dysfunction and impairs cardiac recovery post myocardial ischemia.

    abstract:RATIONALE:Sirtuin (SIRT3), a major nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase in mitochondria, declines with aging and its ablation is associated with accelerated development of cardiovascular diseases. However, the role of SIRT3 in coronary microvascular function and post-MI recovery has not been...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: He X,Zeng H,Chen JX

    更新日期:2016-07-15 00:00:00

  • Beta1-adrenergic receptor polymorphisms, QTc interval and occurrence of symptoms in type 1 of long QT syndrome.

    abstract:BACKGROUND:The most prevalent LQT1 form of inherited long QT syndrome is caused by mutations of the KCNQ1 gene resulting repolarizing I(Ks) potassium current to decrease and the QT interval to prolong. As abrupt sympathetic activation triggers ventricular arrhythmias that may cause syncopal attacks and sudden death in ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Paavonen KJ,Swan H,Piippo K,Laitinen P,Fodstad H,Sarna S,Toivonen L,Kontula K,Viitasalo M

    更新日期:2007-05-31 00:00:00

  • Role of stem cell homing in myocardial regeneration.

    abstract::Recent studies have demonstrated the potential for myocardial regeneration at the time of myocardial infarction. Our lab focuses on understanding how stem cells home to injured tissue. We believe that a detailed analysis of the biological responses to tissue injury not only gives us insight into how damage occurs, but...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Penn MS,Zhang M,Deglurkar I,Topol EJ

    更新日期:2004-06-01 00:00:00

  • Perioperative administration of enoximone and renal function after cardiac surgery: a propensity-matched analysis.

    abstract:BACKGROUND:Perioperative administration of enoximone has been shown to improve hemodynamics, organ function, and inflammatory response. Aim of the present study is to evaluate the impact of enoximone on postoperative renal function after on-pump cardiac surgery. METHODS:A total of 3727 patients undergoing cardiac surg...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Angeloni E,Melina G,Roscitano A,Refice S,Capuano F,Comito C,Benedetto U,Sinatra R

    更新日期:2013-09-01 00:00:00

  • Accuracy of percussion of the left cardiac border.

    abstract:UNLABELLED:The purpose of this study was to determine the accuracy of percussion of the left cardiac border. Sixty-six adult patients were studied. The left cardiac border as determined by percussion and marked with a calibrated lead marker was compared with that obtained by a chest X-ray. The error in locating the lef...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Karnegis JN,Kadri N

    更新日期:1992-12-01 00:00:00

  • Preoperative and perioperative use of levosimendan in cardiac surgery: European expert opinion.

    abstract::In cardiac surgery, postoperative low cardiac output has been shown to correlate with increased rates of organ failure and mortality. Catecholamines have been the standard therapy for many years, although they carry substantial risk for adverse cardiac and systemic effects, and have been reported to be associated with...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Toller W,Heringlake M,Guarracino F,Algotsson L,Alvarez J,Argyriadou H,Ben-Gal T,Černý V,Cholley B,Eremenko A,Guerrero-Orriach JL,Järvelä K,Karanovic N,Kivikko M,Lahtinen P,Lomivorotov V,Mehta RH,Mušič Š,Pollesello P,

    更新日期:2015-04-01 00:00:00

  • Predictors of new onset atrial fibrillation in patients with heart failure.

    abstract:INTRODUCTION:Stroke associated with atrial fibrillation (AF) is more frequent in heart failure. It is unknown what variables predict future AF in these patients and how AF might evolve over time. We investigated this in patients with implantable cardiac defibrillators (ICD) where AF detection is optimal. METHODS:Singl...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Campbell NG,Cantor EJ,Sawhney V,Duncan ER,DeMartini C,Baker V,Diab IG,Dhinoja M,Earley MJ,Sporton S,Davies LC,Schilling RJ

    更新日期:2014-08-01 00:00:00

  • Coronary stent strut fracture after drug-eluting stent implantation: a newly recognized complication.

    abstract::Stent strut fracture (SSF) after drug-eluting stent (DES) implantation may be an important complication after DES implantation particularly in patients undergoing sirolimus eluting stent implantation. Since SSF is a highly relevant adverse event which can result in in-stent restenosis and thrombosis, we believe that D...

    journal_title:International journal of cardiology

    pub_type: 评论,信件


    authors: Celik T,Iyisoy A,Dogru MT,Isik E

    更新日期:2009-02-06 00:00:00

  • Wavelet transform for analysis of heart rate variability preceding ventricular arrhythmias in patients with ischemic heart disease.

    abstract:INTRODUCTION:Studies evaluating changes in HRV preceding the onset of ventricular arrhythmias using conventional techniques have shown inconsistent results. Time-frequency analysis of HRV is traditionally performed using short-term Fourier transform (STFT). Wavelet transform (WT) may however be better suited for analyz...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究


    authors: Burri H,Chevalier P,Arzi M,Rubel P,Kirkorian G,Touboul P

    更新日期:2006-04-28 00:00:00

  • Relationship between QT dispersion and the incidence of early ventricular arrhythmias in patients with acute myocardial infarction.

    abstract::There is controversy about the influence of QT dispersion on the incidence of early ventricular arrhythmias in patients with acute myocardial infarction (AMI). The QT and QTc dispersion (QTd, QTcd) between two groups of patients with AMI were compared: 39 patients with early sustained ventricular tachycardia or ventri...

    journal_title:International journal of cardiology

    pub_type: 临床试验,杂志文章


    authors: Zaputović L,Mavrić Z,Zaninović-Jurjević T,Matana A,Bradić N

    更新日期:1997-12-19 00:00:00

  • Preliminary results of the Multicenter Observational Study with Enoximone in Cardiac surgery (MOSEC).

    abstract:BACKGROUND:Perioperative administration of Enoximone has been shown to improve hemodynamics, organ function, and inflammatory response. Aim of the present study was to evaluate the effects of Enoximone after on-pump cardiac surgery. METHODS:A protocol for a multicenter observational study was reviewed and approved by ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究


    authors: Angeloni E,Melina G,Federici F,Pischedda F,Vignaroli W,Rocco M,Sinatra R,MOSEC Investigators.

    更新日期:2018-10-15 00:00:00

  • Catheter ablation of atrioventricular accessory pathways by radiofrequency current.

    abstract::Tachycardias mediated by atrioventricular accessory pathways, which are refractory to antiarrhythmic drug therapy have been treated both by surgery and by catheter ablation with high energy direct current shock. These procedures have variable success rates and substantial associated morbidity and mortality. Radiofrequ...

    journal_title:International journal of cardiology

    pub_type: 临床试验,杂志文章


    authors: Wang L,Hu D,Ding Y

    更新日期:1993-12-15 00:00:00

  • Left bundle branch block in dilated cardiomyopathy with intermediate left ventricular dysfunction: Clinical phenotyping and outcome correlates.

    abstract:BACKGROUND:Left bundle branch block (LBBB) negatively affects prognosis in heart failure patients with a reduced left ventricular ejection fraction (LVEF). Less is known about the prognostic role of LBBB in dilated cardiomyopathy (DCM) with intermediate LVEF (between 36% and 50%). We sought to assess the role of LBBB i...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Gentile P,Paldino A,Cannatà A,Artico J,Barbati G,Ramani F,Fabris E,Aleksova A,Stolfo D,Zecchin M,Merlo M,Sinagra G

    更新日期:2019-03-01 00:00:00

  • Right ventricular sugars and fats in chronic thromboembolic pulmonary hypertension.

    abstract:BACKGROUND/OBJECTIVES:Several studies have already shown the correlation between the right ventricle (RV) hemodynamic values and either glucose uptake or fatty acid uptake in the RV, respectively. However, there are few studies to compare the RV metabolic alteration before and after treatment for pulmonary hypertension...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Sakao S,Daimon M,Voelkel NF,Miyauchi H,Jujo T,Sugiura T,Ishida K,Tanabe N,Kobayashi Y,Tatsumi K

    更新日期:2016-09-15 00:00:00

  • Effects of bepridil on the resting electrocardiogram.

    abstract::We evaluated the effects of bepridil hydrochloride, a long-acting calcium antagonist, on the electrocardiogram of 13 men with exertional angina. The drug decreased sinus rate (P = 0.01), increased the QT (P less than 0.001) and QTc interval (P less than 0.001), and produced T-wave changes in each patient. ...

    journal_title:International journal of cardiology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Hill JA,Pepine CJ

    更新日期:1984-09-01 00:00:00

  • Interaction between uric acid and endothelial dysfunction predicts new onset of diabetes in hypertensive patients.

    abstract:BACKGROUND:Both uric acid and endothelial dysfunction are associated with new occurrence of type-2 diabetes but, at this moment, there is no evidence about a possible interaction between them. We tested, in untreated hypertensive patients, without clinical evidence of vascular damage, the hypothesis that serum uric aci...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Perticone F,Maio R,Tassone JE,Perticone M,Pascale A,Sciacqua A,Sesti G

    更新日期:2013-07-15 00:00:00

  • Beneficial cumulative role of both nitroglycerin and dobutamine on right ventricular systolic function in congestive heart failure patients awaiting heart transplantation.

    abstract::End-stage idiopathic dilated cardiomyopathy or ischemic heart disease usually present with very low cardiac output and severe ventricular dysfunction which may require pharmacological support before heart transplantation. Right ventricular ejection fraction might be an important factor of functional capacity and survi...

    journal_title:International journal of cardiology

    pub_type: 临床试验,杂志文章


    authors: Juillière Y,Feldmann L,Perrin O,Berder V,Danchin N,Cherrier F

    更新日期:1995-11-10 00:00:00

  • Outpatient volumes and medical staffing resources as predictors for continuity of follow-up care during transfer of adolescents with congenital heart disease.

    abstract:BACKGROUND:Providing continuous follow-up care to patients with congenital heart disease (CHD) remains a challenge in many settings. Previous studies highlight that patients with CHD experience discontinuation of follow-up care, but mainly describe a single-centre perspective, neglecting inter-institutional variations....

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Skogby S,Moons P,Johansson B,Sunnegårdh J,Christersson C,Nagy E,Winberg P,Hanséus K,Trzebiatowska-Krzynska A,Fadl S,Fernlund E,Kazamia K,Rydberg A,Zühlke L,Goossens E,Bratt EL

    更新日期:2020-07-01 00:00:00

  • Ultrafiltration for acute decompensated heart failure: a systematic review and meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Current clinical guidelines recommend ultrafiltration (UF) for patients with acute decompensated heart failure (ADHF) who are unresponsive or resistant to diuretics. We systematically reviewed the latest randomized evidence on the efficacy and safety of UF in ADHF. METHODS:MEDLINE, EMBASE and the Cochrane d...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,meta分析,评审


    authors: Kwong JS,Yu CM

    更新日期:2014-03-15 00:00:00

  • HIV-associated vascular diseases: structural and functional changes, clinical implications.

    abstract::After more than two decades of AIDS epidemic, the spectrum of HIV-associated vascular diseases has mainly evolved from infectious and inflammatory vasculitides to premature atherosclerosis, its related contributing conditions (metabolic syndrome, dyslipidemia, insulin resistance syndrome) and complications (acute coro...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Monsuez JJ,Charniot JC,Escaut L,Teicher E,Wyplosz B,Couzigou C,Vignat N,Vittecoq D

    更新日期:2009-04-17 00:00:00

  • Regulation of QT indices mediated by autonomic nervous function in patients with type 2 diabetes.

    abstract::Both the QT interval and QT dispersion in diabetic patients have been reported to increase with the progression of cardiac autonomic neuropathy and to have a prognostic value. We assessed the cardiac autonomic influences on QT indices using the measurements of baroreflex sensitivity, heart rate variability, and cardia...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Takahashi N,Nakagawa M,Saikawa T,Watanabe M,Ooie T,Yufu K,Shigematsu S,Hara M,Sakino H,Katsuragi I,Tanaka K,Yoshimatsu H

    更新日期:2004-09-01 00:00:00

  • Negative pressure pulmonary edema complicating an electrophysiological study.

    abstract::We report on a case of acute non-cardiogenic negative-pressure pulmonary edema developed during an ablation procedure of an accessory pathway in a patient with no structural heart disease. That potentially serious complication has not been previously reported during an interventional cardiology procedure. ...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Pachón M,Arias MA,Castellanos E,Puchol A,Rodríguez-Padial L

    更新日期:2009-11-12 00:00:00

  • Long term outcome of mechanical valve prosthesis in the pulmonary position.

    abstract:OBJECTIVES:Assessment of the long term outcome of mechanical valve prosthesis at pulmonary position in a population of grown-up congenital heart disease patients from a tertiary referral center. METHODS:From 1977 to 2007, 22 consecutive patients underwent a total of 25 pulmonary valve replacements with mechanical pros...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Dos L,Muñoz-Guijosa C,Mendez AB,Ginel A,Montiel J,Padro JM,Subirana MT

    更新日期:2011-07-15 00:00:00

  • High throughput bioassay for beta1-adrenoceptor autoantibody detection.

    abstract:BACKGROUND:While the involvement of adrenergic beta1-autoantibodies (beta1-AABs) in pathogenesis of cardiomyopathies is well established as are the benefits associated with autoantibody removal by immunoapheresis, the development of drugs neutralizing beta1-AABs in-vivo has been slowed due to a lack of high throughput ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Joshi-Barr S,Haberland A,Bartel S,Müller J,Choi T,Wallukat G

    更新日期:2016-09-15 00:00:00

  • The relevance of health related quality of life in paced patients.

    abstract::With the tremendous advances in cardiac pacing during the past four decades, cardiac pacemaker implantation is now a common clinical procedure. In recent years, the indications for permanent pacemakers have expanded. This increase in reasons for pacing and shift in mode of pacing have been caused by the evolution of p...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Stofmeel MA,van Stel HF,van Hemel NM,Grobbee DE

    更新日期:2005-07-20 00:00:00

  • Differences in inflammatory and thrombotic markers between unstable angina and acute myocardial infarction.

    abstract:BACKGROUND:Unstable coronary syndromes are characterised by increased inflammatory process and endothelial activation. However, the underlying mechanisms of the acute coronary syndromes are still obscure. We evaluated the differences of inflammatory and thrombotic markers, at the acute phase of unstable angina (UA) and...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Tousoulis D,Antoniades C,Bosinakou E,Kotsopoulou M,Tsoufis C,Marinou K,Charakida M,Stefanadi E,Vavuranakis M,Latsios G,Stefanadis C

    更新日期:2007-02-07 00:00:00

  • The specificity of exercise electrocardiography in women grouped by estrogen status.

    abstract::We compared the specificity of exercise electrocardiography in 1880 men and 1818 women with women grouped by menopausal and estrogen replacement status. Specificity for > or = 1 mm horizontal or downsloping ST-segment depression was determined using angiography in 781 patients and using two other nonangiography-based ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Morise AP,Beto R

    更新日期:1997-06-27 00:00:00